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Volumn 15, Issue 63, 2013, Pages 83-90

Intratympanic treatment for tinnitus: A review

Author keywords

Cochlea; Hearing loss; Intratympanic injection; Round window; Tinnitus

Indexed keywords

CHOLINERGIC RECEPTOR STIMULATING AGENT; GLUCOCORTICOID; LOCAL ANESTHETIC AGENT;

EID: 84877284454     PISSN: 14631741     EISSN: 19984030     Source Type: Journal    
DOI: 10.4103/1463-1741.110285     Document Type: Review
Times cited : (15)

References (60)
  • 1
    • 5044221035 scopus 로고    scopus 로고
    • The history of intratympanic drug therapy in otology
    • Lustig LR. The history of intratympanic drug therapy in otology. Otolaryngol Clin North Am 2004;37: 1001-17.
    • (2004) Otolaryngol Clin North Am , vol.37 , pp. 1001-1017
    • Lustig, L.R.1
  • 2
    • 0030941426 scopus 로고    scopus 로고
    • Round window membrane. Structure function and permeability: A review
    • Goycoolea MV, Lundman L. Round window membrane. Structure function and permeability: A review. Microsc Res Tech 1997;36: 201-11.
    • (1997) Microsc Res Tech , vol.36 , pp. 201-211
    • Goycoolea, M.V.1    Lundman, L.2
  • 3
    • 0034927816 scopus 로고    scopus 로고
    • Clinical aspects of round window membrane permeability under normal and pathological conditions
    • Goycoolea MV. Clinical aspects of round window membrane permeability under normal and pathological conditions. Acta Otolaryngol 2001;121: 437-47.
    • (2001) Acta Otolaryngol , vol.121 , pp. 437-447
    • Goycoolea, M.V.1
  • 5
    • 0018871608 scopus 로고
    • The blood-perilymph barrier
    • Jahnke K. The blood-perilymph barrier. Arch Otorhinolaryngol 1980;228: 29-34.
    • (1980) Arch Otorhinolaryngol , vol.228 , pp. 29-34
    • Jahnke, K.1
  • 6
    • 0142156672 scopus 로고    scopus 로고
    • Cortisol levels in the human perilymph after intravenous administration of prednisolone
    • Niedermeyer HP, Zahneisen G, Luppa P, Busch R, Arnold W. Cortisol levels in the human perilymph after intravenous administration of prednisolone. Audiol Neurootol 2003;8: 316-21.
    • (2003) Audiol Neurootol , vol.8 , pp. 316-321
    • Niedermeyer, H.P.1    Zahneisen, G.2    Luppa, P.3    Busch, R.4    Arnold, W.5
  • 7
    • 36549014716 scopus 로고    scopus 로고
    • Intratympanic versus intravenous delivery of methylprednisolone to cochlear perilymph
    • Bird PA, Begg EJ, Zhang M, Keast AT, Murray DP, Balkany TJ. Intratympanic versus intravenous delivery of methylprednisolone to cochlear perilymph. Otol Neurotol 2007;28: 1124-30.
    • (2007) Otol Neurotol , vol.28 , pp. 1124-1130
    • Bird, P.A.1    Begg, E.J.2    Zhang, M.3    Keast, A.T.4    Murray, D.P.5    Balkany, T.J.6
  • 8
    • 33846099985 scopus 로고    scopus 로고
    • Intratympanic dexamethasone for sudden sensorineural hearing loss after failure of systemic therapy
    • Haynes DS, O'Malley M, Cohen S, Watford K, Labadie RF. Intratympanic dexamethasone for sudden sensorineural hearing loss after failure of systemic therapy. Laryngoscope 2007;117: 3-15.
    • (2007) Laryngoscope , vol.117 , pp. 3-15
    • Haynes, D.S.1    O'Malley, M.2    Cohen, S.3    Watford, K.4    Labadie, R.F.5
  • 9
    • 79960025373 scopus 로고    scopus 로고
    • Intratympanic dexamethasone/hyaluronic acid mix as an adjunct to intravenous steroid and vasoactive treatment in patients with severe idiopathic sudden sensorineural hearing loss
    • Gouveris H, Schuler-Schmidt W, Mewes T, Mann W. Intratympanic dexamethasone/hyaluronic acid mix as an adjunct to intravenous steroid and vasoactive treatment in patients with severe idiopathic sudden sensorineural hearing loss. Otol Neurotol 2011;32: 756-60.
    • (2011) Otol Neurotol , vol.32 , pp. 756-760
    • Gouveris, H.1    Schuler-Schmidt, W.2    Mewes, T.3    Mann, W.4
  • 11
    • 0024523306 scopus 로고
    • Computer-aided three-dimensional reconstruction and measurement of the round window niche
    • Takahashi H, Sando I, Takagi A. Computer-aided three-dimensional reconstruction and measurement of the round window niche. Laryngoscope 1989;99: 505-9.
    • (1989) Laryngoscope , vol.99 , pp. 505-509
    • Takahashi, H.1    Sando, I.2    Takagi, A.3
  • 12
    • 73349112869 scopus 로고    scopus 로고
    • Principles of local drug delivery to the inner ear
    • Salt AN, Plontke SK. Principles of local drug delivery to the inner ear. Audiol Neurootol 2009;14: 350-60.
    • (2009) Audiol Neurootol , vol.14 , pp. 350-360
    • Salt, A.N.1    Plontke, S.K.2
  • 13
    • 78651558187 scopus 로고    scopus 로고
    • Safety of intratympanic injection of AM-101 in patients with acute inner ear tinnitus
    • Muehlmeier G, Biesinger E, Maier H. Safety of intratympanic injection of AM-101 in patients with acute inner ear tinnitus. Audiol Neurootol 2011;16: 388-97.
    • (2011) Audiol Neurootol , vol.16 , pp. 388-397
    • Muehlmeier, G.1    Biesinger, E.2    Maier, H.3
  • 14
    • 79957486477 scopus 로고    scopus 로고
    • Oral vs intratympanic corticosteroid therapy for idiopathic sudden sensorineural hearing loss: A randomized trial
    • Rauch SD, Halpin CF, Antonelli PJ, Babu S, Carey JP, Gantz BJ, et al. Oral vs intratympanic corticosteroid therapy for idiopathic sudden sensorineural hearing loss: A randomized trial. JAMA 2011;305: 2071-9.
    • (2011) JAMA , vol.305 , pp. 2071-2079
    • Rauch, S.D.1    Halpin, C.F.2    Antonelli, P.J.3    Babu, S.4    Carey, J.P.5    Gantz, B.J.6
  • 15
    • 23744485714 scopus 로고    scopus 로고
    • Acoustics of the human middle-ear air space
    • Stepp CE, Voss SE. Acoustics of the human middle-ear air space. J Acoust Soc Am 2005;118: 861-71.
    • (2005) J Acoust Soc Am , vol.118 , pp. 861-871
    • Stepp, C.E.1    Voss, S.E.2
  • 16
    • 84877245069 scopus 로고
    • Injection of the tympanum for chronic conductive deafness and associated tinnitus aurium: A preliminary report on the use of ethylmorphine hydrochloride
    • Trowbridge BC. Injection of the tympanum for chronic conductive deafness and associated tinnitus aurium: A preliminary report on the use of ethylmorphine hydrochloride. Arch Otolaryngol 1944;39: 523.
    • (1944) Arch Otolaryngol , vol.39 , pp. 523
    • Trowbridge, B.C.1
  • 17
    • 84877248515 scopus 로고
    • Tympanosympathetic anesthesia for tinnitus aurium and secondary otalgia
    • Trowbridge BC. Tympanosympathetic anesthesia for tinnitus aurium and secondary otalgia. Arch Otolaryngol 1949;50: 200-15.
    • (1949) Arch Otolaryngol , vol.50 , pp. 200-215
    • Trowbridge, B.C.1
  • 18
    • 76549224811 scopus 로고
    • Intratympanic injection for tinnitus aurium
    • Mitchell JF. Intratympanic injection for tinnitus aurium. J Laryngol Otol 1950;64: 576-9.
    • (1950) J Laryngol Otol , vol.64 , pp. 576-579
    • Mitchell, J.F.1
  • 19
    • 84907120762 scopus 로고
    • Die Beeinflussung des Ohrensausens durch iv injizierte Lokalanaesthetica
    • Bárány R. Die Beeinflussung des Ohrensausens durch iv injizierte Lokalanaesthetica. Acta Otolaryngol 1936: 23: 201-3.
    • (1936) Acta Otolaryngol , vol.23 , pp. 201-203
    • Bárány, R.1
  • 20
    • 0001593159 scopus 로고
    • Treatment of tinnitus aurium by the iv use of local anesthetic agents
    • Lewy RB. Treatment of tinnitus aurium by the iv use of local anesthetic agents. Arch Otolaryngol 1937;25: 178-83.
    • (1937) Arch Otolaryngol , vol.25 , pp. 178-183
    • Lewy, R.B.1
  • 22
    • 5044229682 scopus 로고    scopus 로고
    • Intratympanic perfusion for the treatment of tinnitus
    • Dodson KM, Sismanis A. Intratympanic perfusion for the treatment of tinnitus. Otolaryngol Clin North Am 2004;37: 991-1000.
    • (2004) Otolaryngol Clin North Am , vol.37 , pp. 991-1000
    • Dodson, K.M.1    Sismanis, A.2
  • 23
    • 0017052381 scopus 로고
    • Treatment of tinnitus by transtympanic infusion of lidocaine
    • Sakata E, Umeda Y. Treatment of tinnitus by transtympanic infusion of lidocaine. Auris Nasus Larynx 1976;3: 133-8.
    • (1976) Auris Nasus Larynx , vol.3 , pp. 133-138
    • Sakata, E.1    Umeda, Y.2
  • 24
    • 0035682089 scopus 로고    scopus 로고
    • Treatment of cochlear tinnitus with transtympanic infusion of 4% lidocaine into the tympanic cavity
    • Sakata H, Kojima Y, Koyama S, Furuya N, Sakata E. Treatment of cochlear tinnitus with transtympanic infusion of 4% lidocaine into the tympanic cavity. Int Tinnitus J 2001;7: 46-50.
    • (2001) Int Tinnitus J , vol.7 , pp. 46-50
    • Sakata, H.1    Kojima, Y.2    Koyama, S.3    Furuya, N.4    Sakata, E.5
  • 25
    • 0000162213 scopus 로고    scopus 로고
    • Clinical experiences of steroid targeting therapy to inner ear for control of tinnitus
    • Sakata E, Ito Y, Itoh A. Clinical experiences of steroid targeting therapy to inner ear for control of tinnitus. Int Tinnitus J 1997;3: 117-21.
    • (1997) Int Tinnitus J , vol.3 , pp. 117-121
    • Sakata, E.1    Ito, Y.2    Itoh, A.3
  • 26
    • 34250811386 scopus 로고    scopus 로고
    • Treatment of sudden sensorineural hearing loss: I. A systematic review
    • Conlin AE, Parnes LS. Treatment of sudden sensorineural hearing loss: I. A systematic review. Arch Otolaryngol Head Neck Surg 2007;133: 573-81.
    • (2007) Arch Otolaryngol Head Neck Surg , vol.133 , pp. 573-581
    • Conlin, A.E.1    Parnes, L.S.2
  • 27
    • 34250830874 scopus 로고    scopus 로고
    • Treatment of sudden sensorineural hearing loss: II. A Meta-analysis
    • Conlin AE, Parnes LS. Treatment of sudden sensorineural hearing loss: II. A Meta-analysis. Arch Otolaryngol Head Neck Surg 2007;133: 582-6.
    • (2007) Arch Otolaryngol Head Neck Surg , vol.133 , pp. 582-586
    • Conlin, A.E.1    Parnes, L.S.2
  • 28
    • 0031925186 scopus 로고    scopus 로고
    • Dexamethasone inner ear perfusion for the treatment of Meniere's disease: A prospective, randomized, double-blind, crossover trial
    • Silverstein H, Isaacson JE, Olds MJ, Rowan PT, Rosenberg S. Dexamethasone inner ear perfusion for the treatment of Meniere's disease: A prospective, randomized, double-blind, crossover trial. Am J Otol 1998;19: 196-201.
    • (1998) Am J Otol , vol.19 , pp. 196-201
    • Silverstein, H.1    Isaacson, J.E.2    Olds, M.J.3    Rowan, P.T.4    Rosenberg, S.5
  • 29
    • 13444263613 scopus 로고    scopus 로고
    • Intratympanic dexamethasone injections as a treatment for severe, disabling tinnitus: Does it work?
    • Araújo MF, Oliveira CA, Bahmad FM Jr. Intratympanic dexamethasone injections as a treatment for severe, disabling tinnitus: Does it work? Arch Otolaryngol Head Neck Surg 2005;131: 113-7.
    • (2005) Arch Otolaryngol Head Neck Surg , vol.131 , pp. 113-117
    • Araújo, M.F.1    Oliveira, C.A.2    Bahmad Jr., F.M.3
  • 30
    • 66749129819 scopus 로고    scopus 로고
    • Treatment of subjective tinnitus: A comparative clinical study of intratympanic steroid injection versus oral carbamazepine
    • She W, Dai Y, Du X, Chen F, Ding X, Cui X. Treatment of subjective tinnitus: A comparative clinical study of intratympanic steroid injection versus oral carbamazepine. Med Sci Monit 2009;15:PI35-9.
    • (2009) Med Sci Monit , vol.15
    • She, W.1    Dai, Y.2    Du, X.3    Chen, F.4    Ding, X.5    Cui, X.6
  • 31
    • 0030667713 scopus 로고    scopus 로고
    • Caroverine in tinnitus treatment. A placebo-controlled blind study
    • Denk DM, Heinzl H, Franz P, Ehrenberger K. Caroverine in tinnitus treatment. A placebo-controlled blind study. Acta Otolaryngol 1997;117: 825-30.
    • (1997) Acta Otolaryngol , vol.117 , pp. 825-830
    • Denk, D.M.1    Heinzl, H.2    Franz, P.3    Ehrenberger, K.4
  • 33
    • 21444447469 scopus 로고    scopus 로고
    • Topical administration of Caroverine in somatic tinnitus treatment: Proof-of-concept study
    • Ehrenberger K. Topical administration of Caroverine in somatic tinnitus treatment: Proof-of-concept study. Int Tinnitus J 2005;11: 34-7.
    • (2005) Int Tinnitus J , vol.11 , pp. 34-37
    • Ehrenberger, K.1
  • 34
    • 0033838296 scopus 로고    scopus 로고
    • Transtympanic pilocarpine in tinnitus
    • De Lucchi E. Transtympanic pilocarpine in tinnitus. Int Tinnitus J 2000;6: 37-40.
    • (2000) Int Tinnitus J , vol.6 , pp. 37-40
    • De Lucchi, E.1
  • 35
    • 0033956063 scopus 로고    scopus 로고
    • Extraneous round window membranes and plugs: Possible effect on intratympanic therapy
    • Alzamil KS, Linthicum FH Jr. Extraneous round window membranes and plugs: Possible effect on intratympanic therapy. Ann Otol Rhinol Laryngol 2000;109: 30-2.
    • (2000) Ann Otol Rhinol Laryngol , vol.109 , pp. 30-32
    • Alzamil, K.S.1    Linthicum Jr., F.H.2
  • 36
    • 21444434894 scopus 로고    scopus 로고
    • Round-window anatomical considerations in intratympanic drug therapy for inner-ear diseases
    • Penha R, Escada P. Round-window anatomical considerations in intratympanic drug therapy for inner-ear diseases. Int Tinnitus J 2005;11: 31-3.
    • (2005) Int Tinnitus J , vol.11 , pp. 31-33
    • Penha, R.1    Escada, P.2
  • 39
    • 68849124401 scopus 로고    scopus 로고
    • Individual differences in the permeability of the round window: Evaluating the movement of intratympanic gadolinium into the inner ear
    • Yoshioka M, Naganawa S, Sone M, Nakata S, Teranishi M, Nakashima T. Individual differences in the permeability of the round window: Evaluating the movement of intratympanic gadolinium into the inner ear. Otol Neurotol 2009;30: 645-8.
    • (2009) Otol Neurotol , vol.30 , pp. 645-648
    • Yoshioka, M.1    Naganawa, S.2    Sone, M.3    Nakata, S.4    Teranishi, M.5    Nakashima, T.6
  • 40
    • 0036835089 scopus 로고    scopus 로고
    • Analysis of gentamicin kinetics in fluids of the inner ear with round window administration
    • Plontke SK, Wood AW, Salt AN. Analysis of gentamicin kinetics in fluids of the inner ear with round window administration. Otol Neurotol 2002;23: 967-74.
    • (2002) Otol Neurotol , vol.23 , pp. 967-974
    • Plontke, S.K.1    Wood, A.W.2    Salt, A.N.3
  • 41
    • 5044231880 scopus 로고    scopus 로고
    • The biology of intratympanic drug administration and pharmacodynamics of round window drug absorption
    • Banerjee A, Parnes LS. The biology of intratympanic drug administration and pharmacodynamics of round window drug absorption. Otolaryngol Clin North Am 2004;37: 1035-51.
    • (2004) Otolaryngol Clin North Am , vol.37 , pp. 1035-1051
    • Banerjee, A.1    Parnes, L.S.2
  • 42
    • 80051736576 scopus 로고    scopus 로고
    • Intratympanic versus intravenous delivery of dexamethasone and dexamethasone sodium phosphate to cochlear perilymph
    • Bird PA, Murray DP, Zhang M, Begg EJ. Intratympanic versus intravenous delivery of dexamethasone and dexamethasone sodium phosphate to cochlear perilymph. Otol Neurotol 2011;32: 933-6.
    • (2011) Otol Neurotol , vol.32 , pp. 933-936
    • Bird, P.A.1    Murray, D.P.2    Zhang, M.3    Begg, E.J.4
  • 44
    • 41349085428 scopus 로고    scopus 로고
    • Dexamethasone concentration gradients along scala tympani after application to the round window membrane
    • Plontke SK, Biegner T, Kammerer B, Delabar U, Salt AN. Dexamethasone concentration gradients along scala tympani after application to the round window membrane. Otol Neurotol 2008;29: 401-6.
    • (2008) Otol Neurotol , vol.29 , pp. 401-406
    • Plontke, S.K.1    Biegner, T.2    Kammerer, B.3    Delabar, U.4    Salt, A.N.5
  • 45
    • 58149354604 scopus 로고    scopus 로고
    • State-of-the-art mechanisms of intracochlear drug delivery
    • Borkholder DA. State-of-the-art mechanisms of intracochlear drug delivery. Curr Opin Otolaryngol Head Neck Surg 2008;16: 472-7.
    • (2008) Curr Opin Otolaryngol Head Neck Surg , vol.16 , pp. 472-477
    • Borkholder, D.A.1
  • 47
    • 33645955238 scopus 로고    scopus 로고
    • Cochlear protection by local insulin-like growth factor-1 application using biodegradable hydrogel
    • Iwai K, Nakagawa T, Endo T, Matsuoka Y, Kita T, Kim TS, et al. Cochlear protection by local insulin-like growth factor-1 application using biodegradable hydrogel. Laryngoscope 2006;116: 529-33.
    • (2006) Laryngoscope , vol.116 , pp. 529-533
    • Iwai, K.1    Nakagawa, T.2    Endo, T.3    Matsuoka, Y.4    Kita, T.5    Kim, T.S.6
  • 49
    • 9644260483 scopus 로고    scopus 로고
    • Direct round window application of gentamicin with varying delivery vehicles: A comparison of ototoxicity
    • Sheppard WM, Wanamaker HH, Pack A, Yamamoto S, Slepecky N. Direct round window application of gentamicin with varying delivery vehicles: A comparison of ototoxicity. Otolaryngol Head Neck Surg 2004;131: 890-6.
    • (2004) Otolaryngol Head Neck Surg , vol.131 , pp. 890-896
    • Sheppard, W.M.1    Wanamaker, H.H.2    Pack, A.3    Yamamoto, S.4    Slepecky, N.5
  • 51
    • 78650238229 scopus 로고    scopus 로고
    • Distribution of dexamethasone and preservation of inner ear function following intratympanic delivery of a gel-based formulation
    • Salt AN, Hartsock J, Plontke S, Le Bel C, Piu F. Distribution of dexamethasone and preservation of inner ear function following intratympanic delivery of a gel-based formulation. Audiol Neurootol 2011;16: 323-35.
    • (2011) Audiol Neurootol , vol.16 , pp. 323-335
    • Salt, A.N.1    Hartsock, J.2    Plontke, S.3    Le Bel, C.4    Piu, F.5
  • 54
    • 59849084412 scopus 로고    scopus 로고
    • Permeability of the round window membrane is influenced by the composition of applied drug solutions and by common surgical procedures
    • Mikulec AA, Hartsock JJ, Salt AN. Permeability of the round window membrane is influenced by the composition of applied drug solutions and by common surgical procedures. Otol Neurotol 2008;29: 1020-6.
    • (2008) Otol Neurotol , vol.29 , pp. 1020-1026
    • Mikulec, A.A.1    Hartsock, J.J.2    Salt, A.N.3
  • 55
    • 38649097198 scopus 로고    scopus 로고
    • Cytotoxic effects of dimethyl sulphoxide (DMSO) on cochlear organotypic cultures
    • Qi W, Ding D, Salvi RJ. Cytotoxic effects of dimethyl sulphoxide (DMSO) on cochlear organotypic cultures. Hear Res 2008;236: 52-60.
    • (2008) Hear Res , vol.236 , pp. 52-60
    • Qi, W.1    Ding, D.2    Salvi, R.J.3
  • 56
    • 84871331685 scopus 로고    scopus 로고
    • Pain assessment of the intratympanic injections: A prospective comparative study
    • Belhassen S, Saliba I. Pain assessment of the intratympanic injections: A prospective comparative study. Eur Arch Otorhinolaryngol 2012;269: 2467-73.
    • (2012) Eur Arch Otorhinolaryngol , vol.269 , pp. 2467-2473
    • Belhassen, S.1    Saliba, I.2
  • 57
    • 0037340974 scopus 로고    scopus 로고
    • Morphologic changes in round window membrane after topical hydrocortisone and dexamethasone treatment
    • Nordang L, Linder B, Anniko M. Morphologic changes in round window membrane after topical hydrocortisone and dexamethasone treatment. Otol Neurotol 2003;24: 339-43.
    • (2003) Otol Neurotol , vol.24 , pp. 339-343
    • Nordang, L.1    Linder, B.2    Anniko, M.3


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