Toll-like receptor 9 deficiency protects mice against Pseudomonas aeruginosa lung infection

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  BenMohamed, Fatima ^a,b   Medina, Mathieu ^a,b   Wu, Yong Zheng ^a,b   Maschalidi, Sophia ^b   Jouvion, Gregory ^a   Guillemot, Laurent ^a,b   Chignard, Michel ^a,b   Manoury, Bénédicte ^b   Touqui, Lhousseine ^a,b  

^a INSTITUT PASTEUR   (France)

^b INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE ENDOPEPTIDASE; BACTERIAL DNA; INTERLEUKIN 1BETA; INTERLEUKIN 6; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROTEINASE; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CPG-OLIGONUCLEOTIDE; CYTOKINE; INDUCIBLE NITRIC OXIDE SYNTHASE; OLIGODEOXYRIBONUCLEOTIDE; TLR4 PROTEIN, MOUSE; TLR9 PROTEIN, MOUSE; TOLL LIKE RECEPTOR 4;

ACIDIFICATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL CLEARANCE; BACTERICIDAL ACTIVITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENDOSOME; FEMALE; HOST RESISTANCE; INFECTION RESISTANCE; LETHALITY; LUNG ALVEOLUS MACROPHAGE; LUNG INFECTION; MOUSE; NONHUMAN; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL SEPARATION; DEFICIENCY; DRUG EFFECTS; IMMUNOLOGY; INNATE IMMUNITY; LUNG; MALE; METABOLISM; MICROBIAL VIABILITY; MICROBIOLOGY; PATHOLOGY; PH; PHYSIOLOGY; PNEUMONIA; PSEUDOMONAS INFECTIONS; SIGNAL TRANSDUCTION; SURVIVAL;

ANIMALS; CELL SEPARATION; CYTOKINES; DNA, BACTERIAL; ENDOSOMES; FEMALE; HYDROGEN-ION CONCENTRATION; IMMUNITY, INNATE; LUNG; MACROPHAGES, ALVEOLAR; MALE; MICE, INBRED C57BL; MICROBIAL VIABILITY; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OLIGODEOXYRIBONUCLEOTIDES; PNEUMONIA; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTOR 9;

EID: 84897072750     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0090466     Document Type: Article

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