메뉴 건너뛰기




Volumn 18, Issue 2, 2006, Pages 355-363

Up-regulation of Fas expression by Pseudomonas aeruginosa-infected endothelial cells depends on modulation of iNOS and enhanced production of NO induced by bacterial type III secreted proteins

Author keywords

Apoptosis; Fas FasL system; Human umbilical vein endothelial cells; iNOS; NO; P. Aeruginosa; Type III secretion system

Indexed keywords

BACTERIAL PROTEIN; ENZYME INHIBITOR; FAS ANTIGEN; FAS LIGAND; INDUCIBLE NITRIC OXIDE SYNTHASE; N(G) METHYLARGININE; NITRIC OXIDE;

EID: 36048941441     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.18.2.355     Document Type: Article
Times cited : (9)

References (64)
  • 1
    • 0028605175 scopus 로고
    • Apoptosis in bacterial pathogenesis
    • Zychlinsky A and Sansonetti PL: Apoptosis in bacterial pathogenesis. Microb Pathog 17: 203-212, 1994.
    • (1994) Microb Pathog , vol.17 , pp. 203-212
    • Zychlinsky, A.1    Sansonetti, P.L.2
  • 2
    • 0029880871 scopus 로고
    • Differential induction of apoptosis in lymphoid tissues during sepsis; variation in onset, frequency, and the nature of the mediators
    • Ayala A, Hemdom C, Lehman D, Ayala CD and Chandry LH: Differential induction of apoptosis in lymphoid tissues during sepsis; variation in onset, frequency, and the nature of the mediators. Blood 87: 4261-4275, 1986.
    • (1986) Blood , vol.87 , pp. 4261-4275
    • Ayala, A.1    Hemdom, C.2    Lehman, D.3    Ayala, C.D.4    Chandry, L.H.5
  • 3
    • 0030739250 scopus 로고    scopus 로고
    • Apoptosis in lymphoid and parenchymal cells during sepsis: Findings in norm al and T- and B-cell deficient mice
    • Hotchkiss RS, Swanson PE, Cobb JP, Jacobson A, Buchman TG and Karl LA: Apoptosis in lymphoid and parenchymal cells during sepsis: findings in norm al and T- and B-cell deficient mice. Crit Care Med 25: 1298-1307, 1997.
    • (1997) Crit Care Med , vol.25 , pp. 1298-1307
    • Hotchkiss, R.S.1    Swanson, P.E.2    Cobb, J.P.3    Jacobson, A.4    Buchman, T.G.5    Karl, L.A.6
  • 5
    • 0031741285 scopus 로고    scopus 로고
    • Internalization of Staphylococcus aureus by endothelial cells induces apoptosis
    • Menzies BE and Kourteva L: Internalization of Staphylococcus aureus by endothelial cells induces apoptosis. Infect Immun 66: 431-439, 1998.
    • (1998) Infect Immun , vol.66 , pp. 431-439
    • Menzies, B.E.1    Kourteva, L.2
  • 8
    • 4344701680 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa-induced production of free radicals by IFNγ plus TNFα-activated endothelial cells: Mechanism of host defense or of bacterial pathogenesis?
    • Assis MC, Saliba AM, Vidipó LA, Salles J and Plotkowski MC: Pseudomonas aeruginosa-induced production of free radicals by IFNγ plus TNFα-activated endothelial cells: mechanism of host defense or of bacterial pathogenesis? Immunol Cell Biol 82: 383-392, 2004.
    • (2004) Immunol Cell Biol , vol.82 , pp. 383-392
    • Assis, M.C.1    Saliba, A.M.2    Vidipó, L.A.3    Salles, J.4    Plotkowski, M.C.5
  • 9
    • 0028176651 scopus 로고
    • Oxidative stress as a mediator of apoptosis
    • Buttke TM and Sandstrom PA: Oxidative stress as a mediator of apoptosis. Immunol Today 15: 7-10, 1994.
    • (1994) Immunol Today , vol.15 , pp. 7-10
    • Buttke, T.M.1    Sandstrom, P.A.2
  • 10
    • 0029873387 scopus 로고    scopus 로고
    • Reactive oxygen species and programmed cell death
    • DOI 10.1016/0968-0004(96)20008-8
    • Jacobson MD: Reactive oxygen species and programmed cell death. Trends Biochem Sci 21: 83-86, 1996. (Pubitemid 26088517)
    • (1996) Trends in Biochemical Sciences , vol.21 , Issue.3 , pp. 83-86
    • Jacobson, M.D.1
  • 11
    • 0028061554 scopus 로고
    • The Fas/APO-1 receptor and its deadly ligand
    • Schulze-Osthoff K: The Fas/APO-1 receptor and its deadly ligand. Trends Cell Biol 4: 421-426, 1994.
    • (1994) Trends Cell Biol , vol.4 , pp. 421-426
    • Schulze-Osthoff, K.1
  • 12
    • 16844381848 scopus 로고    scopus 로고
    • The extracellular domains of FasL and Fas are sufficient for the formation of supramolecular FasL-Fas clusters of high stability
    • DOI 10.1083/jcb.200501048
    • Henkler F, Behrle E, Dennehy KM, Wicovsky A, Peters N and Warnke C: The extracellular domains of FasL and Fas are sufficient for the formation of supramolecular FasL-Fas clusters of high stability. J Cell Biol 168: 1087-1098, 2005. (Pubitemid 40491178)
    • (2005) Journal of Cell Biology , vol.168 , Issue.7 , pp. 1087-1098
    • Henkler, F.1    Behrle, E.2    Dennehy, K.M.3    Wicovsky, A.4    Peters, N.5    Warnke, C.6    Pfizenmaier, K.7    Wajant, H.8
  • 13
    • 0033761316 scopus 로고    scopus 로고
    • Host defense to Pseudomonas aeruginosa requires CD95/CD95 ligand interactions on epithelial cells
    • Grassmé H, Kirschnek S, Riethmueller J, Riehle A, von Kurthy G and Lang F: Host defense to Pseudomonas aeruginosa requires CD95/CD95 ligand interactions on epithelial cells. Science 290: 527-530, 2000.
    • (2000) Science , vol.290 , pp. 527-530
    • Grassmé, H.1    Kirschnek, S.2    Riethmueller, J.3    Riehle, A.4    Von Kurthy, G.5    Lang, F.6
  • 14
    • 0035086284 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa-induced apoptosis involves mitochondria and stress-activated protein kinases
    • Jendrossek V, Grassmé H, Mueller I, Lang F and Gulbins E: Pseudomonas aeruginosa-induced apoptosis involves mitochondria and stress-activated protein kinases. Infect Immun 69: 2675-2683, 2001.
    • (2001) Infect Immun , vol.69 , pp. 2675-2683
    • Jendrossek, V.1    Grassmé, H.2    Mueller, I.3    Lang, F.4    Gulbins, E.5
  • 15
    • 0037408254 scopus 로고    scopus 로고
    • Apoptotic response of Chang cells to infection with Pseudomonas aeruginosa strains PAK and PAO-I: Molecular ordering of the apoptosis signaling cascade and role of type IV pili
    • Jendrossek V, Fillon S, Belka C, Muller I, Puttkamme B and Lang F: Apoptotic response of Chang cells to infection with Pseudomonas aeruginosa strains PAK and PAO-I: molecular ordering of the apoptosis signaling cascade and role of type IV pili. Infect Immun 71: 2665-2673, 2003.
    • (2003) Infect Immun , vol.71 , pp. 2665-2673
    • Jendrossek, V.1    Fillon, S.2    Belka, C.3    Muller, I.4    Puttkamme, B.5    Lang, F.6
  • 16
    • 0041701380 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa-induced apoptosis is defective in respiratory epithelial cells expressing mutant cystic fibrosis transmembrane conductance regulator
    • Cannon CL, Kowalski MP, Stopak KS and Pier GB: Pseudomonas aeruginosa-induced apoptosis is defective in respiratory epithelial cells expressing mutant cystic fibrosis transmembrane conductance regulator. Am J Respir Cell Mol Biol 29: 188-197, 2003.
    • (2003) Am J Respir Cell Mol Biol , vol.29 , pp. 188-197
    • Cannon, C.L.1    Kowalski, M.P.2    Stopak, K.S.3    Pier, G.B.4
  • 17
    • 0031864184 scopus 로고    scopus 로고
    • Type III protein secretion systems in bacterial pathogens of animals and plants
    • Hueck CJ: Type III protein secretion systems in bacterial pathogens of animals and plants. Mol Biol Rev 62: 379-433, 1998. (Pubitemid 28270280)
    • (1998) Microbiology and Molecular Biology Reviews , vol.62 , Issue.2 , pp. 379-433
    • Hueck, C.J.1
  • 18
    • 0029162189 scopus 로고
    • Analyses of the DNA-binding and transcriptional activation properties of ExsA, the transcriptional activator of the Pseudomonas aeruginosa exoenzyme S regulon
    • Hovey AK and Frank DW: Analyses of the DNA-binding and transcriptional activation properties of ExsA, the transcriptional activator of the Pseudomonas aeruginosa exoenzyme S regulon. J Bacteriol 177: 4427-4436, 1995.
    • (1995) J Bacteriol , vol.177 , pp. 4427-4436
    • Hovey, A.K.1    Frank, D.W.2
  • 19
    • 0028050672 scopus 로고
    • Exoproduct secretions of P. aeruginosa strains influence severity of alveolar epithelial injury
    • Kudoh I, Wiener-Kronish JP, Hashimoto S, Pittet JF and Frank D: Exoproduct secretions of P. aeruginosa strains influence severity of alveolar epithelial injury. Am J Physiol 267: L551-L556, 1994.
    • (1994) Am J Physiol , vol.267
    • Kudoh, I.1    Wiener-Kronish, J.P.2    Hashimoto, S.3    Pittet, J.F.4    Frank, D.5
  • 20
    • 0031020233 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa-mediated cytotoxicity and invasion correlate with distinct genotypes at the loci encoding exoenzyme S
    • Fleiszig SMJ, Wiener-Kronish JP, Miyazaki H, Vallas V, Mostov KE and Kanada D: Pseudomonas aeruginosa-mediated cytotoxicity and invasion correlate with distinct genotypes at the loci encoding exoenzyme S. Infect Immun 65: 579-586, 1997.
    • (1997) Infect Immun , vol.65 , pp. 579-586
    • Fleiszig, S.M.J.1    Wiener-Kronish, J.P.2    Miyazaki, H.3    Vallas, V.4    Mostov, K.E.5    Kanada, D.6
  • 21
    • 0033031869 scopus 로고    scopus 로고
    • Macrophage and epithelial cells respond differently to the Pseudomonas aeruginosa type III secretion system
    • Coburn J and Frank DW: Macrophage and epithelial cells respond differently to the Pseudomonas aeruginosa type III secretion system. Infect Immun 67: 3151-3154, 1999.
    • (1999) Infect Immun , vol.67 , pp. 3151-3154
    • Coburn, J.1    Frank, D.W.2
  • 22
  • 25
    • 0022445670 scopus 로고
    • Rapid colorimetric assay for cell growth and survival. Modification of the tetrazolium dye procedure giving improved sensibility and reliability
    • Denizot S and Lange R: Rapid colorimetric assay for cell growth and survival. Modification of the tetrazolium dye procedure giving improved sensibility and reliability. J Immunol Methods 89: 271-277, 1986.
    • (1986) J Immunol Methods , vol.89 , pp. 271-277
    • Denizot, S.1    Lange, R.2
  • 27
    • 0027989808 scopus 로고
    • Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis
    • Koopman G, Reutelingsperger CPM, Kuijten GAM, Keehnen K, Pals ST and van Oers HS: Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood 84: 1415-1420, 1994. (Pubitemid 24273007)
    • (1994) Blood , vol.84 , Issue.5 , pp. 1415-1420
    • Koopman, G.1    Reutelingsperger, C.P.M.2    Kuijten, G.A.M.3    Keehnen, R.M.J.4    Pals, S.T.5    Van Oers, M.H.J.6
  • 28
  • 30
  • 31
    • 0023771786 scopus 로고    scopus 로고
    • Potencial for free radical-induced lipid peroxidation as a cause of endothelial cell injury in Rocky Moutain spotted fever
    • Silverman DJ and Santucci LA: Potencial for free radical-induced lipid peroxidation as a cause of endothelial cell injury in Rocky Moutain spotted fever. Infect Immun 56: 3110-3115, 1998.
    • (1998) Infect Immun , vol.56 , pp. 3110-3115
    • Silverman, D.J.1    Santucci, L.A.2
  • 32
    • 0032038643 scopus 로고    scopus 로고
    • Superoxide Dismutase-Dependent, Catalase-Sensitive Peroxides in Human Endothelial Cells Infected by Rickettsia rickettsii
    • Hong Y, Santucci LA, Tian X and Silverman DJ: Superoxide dismutase-dependent, catalase-sensitive peroxides in human endothelial cells infected by Rickettsia rickettsii. Infect Immun 66: 1293-1298, 1998. (Pubitemid 128471482)
    • (1998) Infection and Immunity , vol.66 , Issue.4 , pp. 1293-1298
    • Hong, J.E.1    Santucci, L.A.2    Tian, X.3    Silverman, D.J.4
  • 33
    • 0031948653 scopus 로고    scopus 로고
    • Nitric oxide is produced by Cowdria rumunantium infected bovine pulmonary endothelial cells in vitro and is stimulated by gama interferon
    • Mutunga M, Preston PM and Sumption K: Nitric oxide is produced by Cowdria rumunantium infected bovine pulmonary endothelial cells in vitro and is stimulated by gama interferon. Infect Immun 66: 2115-2121, 1998.
    • (1998) Infect Immun , vol.66 , pp. 2115-2121
    • Mutunga, M.1    Preston, P.M.2    Sumption, K.3
  • 34
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology and pharmacology
    • Moncada S, Palmer RM and Higgs EA: Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol Rev 43: 109-142, 1990.
    • (1990) Pharmacol Rev , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.2    Higgs, E.A.3
  • 35
    • 0034527469 scopus 로고    scopus 로고
    • Expression of inducible nitric oxide synthase and Fas/Fas ligand correlates with the incidence of apoptotic cell death in atheromatous plaques of human coronary arteries
    • DOI 10.1006/niox.2000.0311
    • Esaki T, Hayashim T, Mutuo E, Kano H, Kumar TN and Asai Y: Expression of iNOS and Fas/Fas ligand correlates with the incidence of apoptotic cell death in atheromatous plaques of human coronary arteries. Nitric Oxide Biol Chem 4: 561-571, 2000. (Pubitemid 32053267)
    • (2000) Nitric Oxide - Biology and Chemistry , vol.4 , Issue.6 , pp. 561-571
    • Esaki, T.1    Hayashi, T.2    Muto, E.3    Kano, H.4    Kumar, T.N.5    Asai, Y.6    Sumi, D.7    Iguchi, A.8
  • 36
    • 0036481660 scopus 로고    scopus 로고
    • Microencapsulated iNOS-expressing cells cause tumor suppression in mice
    • Xu W, Liu L and Charles IG: Microencapsulated iNOS-expressing cells cause tumor suppression in mice. FASEB J 16: 213-216, 2002.
    • (2002) FASEB J , vol.16 , pp. 213-216
    • Xu, W.1    Liu, L.2    Charles, I.G.3
  • 37
    • 0032879168 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa induces type-III-secretion-mediated apoptosis of macrophages and epithelial cells
    • Hauser AR and Engel JN: Pseudomonas aeruginosa induces type-III-secretion-mediated apoptosis of macrophages and epithelial cells. Infect Immun 67: 5530-5537, 1999.
    • (1999) Infect Immun , vol.67 , pp. 5530-5537
    • Hauser, A.R.1    Engel, J.N.2
  • 38
    • 0033839992 scopus 로고    scopus 로고
    • Exoenzyme S from Pseudomonas aeruginosa induces apoptosis in T lymphocytes
    • Bruno TF, Woods DE and Mody CH: Exoenzyme S from Pseudomonas aeruginosa induces apoptosis in T lymphocytes. J Leukoc Biol 67: 808-816, 2000.
    • (2000) J Leukoc Biol , vol.67 , pp. 808-816
    • Bruno, T.F.1    Woods, D.E.2    Mody, C.H.3
  • 39
    • 0033753988 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa mediated apoptosis requires the ADP-ribosylating activity of ExoS
    • Kaufman MR, Jinghwa J, Zeng L, Ha U, Chow M and Jin S: Pseudomonas aeruginosa mediated apoptosis requires the ADP-ribosylating activity of ExoS. Microbiol 146: 2531-2541, 2000.
    • (2000) Microbiol , vol.146 , pp. 2531-2541
    • Kaufman, M.R.1    Jinghwa, J.2    Zeng, L.3    Ha, U.4    Chow, M.5    Jin, S.6
  • 41
    • 0038781803 scopus 로고    scopus 로고
    • c-Jun NH2-terminal kinase-mediated signaling is essential for Pseudomonas aeruginosa ExoS-induced apoptosis
    • Jia J, Alaoui-El-Azher M, Chow M, Chambers TC, Baker H and Jin S: c-Jun NH2-terminal kinase-mediated signaling is essential for Pseudomonas aeruginosa ExoS-induced apoptosis. Infect Immun 71: 3361-3370, 2003.
    • (2003) Infect Immun , vol.71 , pp. 3361-3370
    • Jia, J.1    Alaoui-El-Azher, M.2    Chow, M.3    Chambers, T.C.4    Baker, H.5    Jin, S.6
  • 43
    • 0036893444 scopus 로고    scopus 로고
    • The bacterial redox protein azurin induces apoptosis in J774 macrophages through complex formation and stabilization of the tumor suppressor protein p53
    • Yamada T, Goto M, Punj V, Zaborina O, das Gupta TK, Kimbara K and Chakrabarty AM: The bacterial redox protein azurin induces apoptosis in J774 macrophages through complex formation and stabilization of the tumor suppressor protein p53. Infect Immun 70: 7054-7062, 2002.
    • (2002) Infect Immun , vol.70 , pp. 7054-7062
    • Yamada, T.1    Goto, M.2    Punj, V.3    Zaborina, O.4    Das Gupta, T.K.5    Kimbara, K.6    Chakrabarty, A.M.7
  • 44
    • 0037239225 scopus 로고    scopus 로고
    • Induction of apoptosis in macrophages by Pseudomonas aeruginosa azurin: Tumour-suppressor protein p53 and reactive oxygen species, but not redox activity, as critical elements in cytotoxicity
    • Goto M, Yamada T, Kimbara K, Horner J, Newcomb M, GuptaTK and Chakrabarty AM: Induction of apoptosis in macrophages by Pseudomonas aeruginosa azurin: tumour-suppressor protein p53 and reactive oxygen species, but not redox activity, as critical elements in cytotoxicity. Mol Microbiol 47: 549-559, 2003.
    • (2003) Mol Microbiol , vol.47 , pp. 549-559
    • Goto, M.1    Yamada, T.2    Kimbara, K.3    Horner, J.4    Newcomb, M.5    Gupta, T.K.6    Chakrabarty, A.M.7
  • 45
    • 0141739361 scopus 로고    scopus 로고
    • The multiple roles of Fas ligand in the pathogenesis of infectious diseases
    • DOI 10.1046/j.1469-0691.2003.00669.x
    • Dockrell DH: The multiple roles of Fas ligand in the pathogenesis of infectious diseases. Clin Microbiol Infect 9: 766-779, 2003. (Pubitemid 37121078)
    • (2003) Clinical Microbiology and Infection , vol.9 , Issue.8 , pp. 766-779
    • Dockrell, D.H.1
  • 46
    • 0037298345 scopus 로고    scopus 로고
    • Dual response to Fas ligation in human endothelial cells: Apoptosis and induction of chemokines, IL-8 and monocyte chemoattractant protein-1
    • Yamaoka-Tojo M, Yamaguchi S, Nitobe J, Abe S, Inoue S and Ozaki N: Dual response to Fas ligation in human endothelial cells: apoptosis and induction of chemokines, IL-8 and monocyte chemoattractant protein-1. Coron Artery Dis 14: 89-94, 2003.
    • (2003) Coron Artery Dis , vol.14 , pp. 89-94
    • Yamaoka-Tojo, M.1    Yamaguchi, S.2    Nitobe, J.3    Abe, S.4    Inoue, S.5    Ozaki, N.6
  • 47
    • 0032550366 scopus 로고    scopus 로고
    • Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity
    • DOI 10.1084/jem.187.8.1205
    • Schneider P, Holler N, Bodmer JL, Hahne M, Frei K, Fontana A and Tschopp J: Conversion of membrane-bound Fas (CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity. J Exp Med 187: 1205-1213, 1998. (Pubitemid 28189110)
    • (1998) Journal of Experimental Medicine , vol.187 , Issue.8 , pp. 1205-1213
    • Schneider, P.1    Holler, N.2    Bodmer, J.-L.3    Hahne, M.4    Frei, K.5    Fontana, A.6    Tschopp, J.7
  • 48
    • 0031452949 scopus 로고    scopus 로고
    • Membrane Fas ligand kills human peripheral blood T lymphocytes, and soluble fas ligand blocks the killing
    • DOI 10.1084/jem.186.12.2045
    • Suda TH, Hashimoto M, Tanaka T, Ochi T and Nagata S: Membrane Fas ligand kills human peripheral blood T lymphocytes, and soluble Fas ligand blocks the killing. J Exp Med 186: 2045-2050, 1997. (Pubitemid 28013689)
    • (1997) Journal of Experimental Medicine , vol.186 , Issue.12 , pp. 2045-2050
    • Suda, T.1    Hashimoto, H.2    Tanaka, M.3    Ochi, T.4    Nagata, S.5
  • 49
    • 0035256309 scopus 로고    scopus 로고
    • Hypoxia stimulates release of the soluble form of Fas ligand that inhibits endothelial cell apoptosis
    • Mogi M, Fukuo K, Yang J, Suhara T and Ogihara T: Hypoxia stimulates release of the soluble form of Fas that inhibits endothelial cell apoptosis. Lab Invest 81: 177-184, 2001. (Pubitemid 32176381)
    • (2001) Laboratory Investigation , vol.81 , Issue.2 , pp. 177-184
    • Mogi, M.1    Fukuo, K.2    Yang, J.3    Suhara, T.4    Ogihara, T.5
  • 50
    • 0037315457 scopus 로고    scopus 로고
    • Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex
    • Holler N, Tardivel M, Kovacsovics-Bankowski S, Hertig O, Gaide F and Martinon A: Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex. Mol Cell Biol 23: 1428-1440, 2003.
    • (2003) Mol Cell Biol , vol.23 , pp. 1428-1440
    • Holler, N.1    Tardivel, M.2    Kovacsovics-Bankowski, S.3    Hertig, O.4    Gaide, F.5    Martinon, A.6
  • 51
    • 13244296902 scopus 로고    scopus 로고
    • Nitric oxide, cell signaling and cell death
    • DOI 10.1016/j.tox.2004.11.032, PII S0300483X04006717, Nitric Oxide, Cell Signalling and Death
    • Blaise GA, Gauvin D, Gangal M and Authier S: Nitric oxide, cell signaling and cell death. Toxicology 208: 177-192, 2005. (Pubitemid 40187330)
    • (2005) Toxicology , vol.208 , Issue.2 , pp. 177-192
    • Blaise, G.A.1    Gauvin, D.2    Gangal, M.3    Authier, S.4
  • 52
    • 2542455472 scopus 로고    scopus 로고
    • INOS-mediated nitric oxide production and its regulation
    • DOI 10.1016/j.lfs.2003.10.042, PII S0024320504002887
    • Aktan F: iNOS-mediated nitric oxide production and its regulation. Life Sci 75: 639-653, 2004. (Pubitemid 38686696)
    • (2004) Life Sciences , vol.75 , Issue.6 , pp. 639-653
    • Aktan, F.1
  • 53
    • 0041842728 scopus 로고    scopus 로고
    • Analysis of Pseudomonas aeruginosa corneal infection using an oligonucleotide microarray
    • Huang X and Hazlett LD: Analysis of Pseudomonas aeruginosa corneal infection using an oligonucleotide microarray. Invest Ophthalmol Vis Sci 44: 3409-3416, 2003.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 3409-3416
    • Huang, X.1    Hazlett, L.D.2
  • 54
    • 0033806481 scopus 로고    scopus 로고
    • Salmonella enterica serovar typhimurium-dependent regulation of inducible nitric oxide synthase expression in macrophages by invasins SipB, SipC, and SipD and effector SopE2
    • Cherayil BJ, McCormick BA and Bosley J: Salmonella enterica serovar typhimurium-dependent regulation of inducible nitric oxide synthase expression in macrophages by invasins SipB, SipC, and SipD and effector SopE2. Infect Immun 68: 5567-5574, 2000.
    • (2000) Infect Immun , vol.68 , pp. 5567-5574
    • Cherayil, B.J.1    McCormick, B.A.2    Bosley, J.3
  • 56
    • 0036087275 scopus 로고    scopus 로고
    • Microtubule-active agents modify nitric oxide production in pulmonary artery endothelial cells
    • Su Y, Zharikov SI and Block ER: Microtubule-active agents modify nitric oxide production in pulmonary artery endothelial cells. Am J Physiol Lung Cell Mol Physiol 282: L1183-L1189, 2002.
    • (2002) Am J Physiol Lung Cell Mol Physiol , vol.282
    • Su, Y.1    Zharikov, S.I.2    Block, E.R.3
  • 57
    • 0034823919 scopus 로고    scopus 로고
    • Disruption of the actin cytoskeleton regulates cytokine-induced iNOS expression
    • Zeng C and Morrison AR: Disruption of the actin cytoskeleton regulates cytokine-induced iNOS expression. Am J Physiol Cell Physiol 281: C932-C940, 2001.
    • (2001) Am J Physiol Cell Physiol , vol.281
    • Zeng, C.1    Morrison, A.R.2
  • 58
    • 1642540972 scopus 로고    scopus 로고
    • Disruption of the actin cytoskeleton upregulates iNOS expression in vascular smooth muscle cells
    • Hattori Y and Kasai K: Disruption of the actin cytoskeleton upregulates iNOS expression in vascular smooth muscle cells. J Cardiovasc Pharmacol 43: 209-213, 2004.
    • (2004) J Cardiovasc Pharmacol , vol.43 , pp. 209-213
    • Hattori, Y.1    Kasai, K.2
  • 59
    • 0030922964 scopus 로고    scopus 로고
    • Intracellular targeting of exoenzyme S of Pseudomonas aeruginosa via type III-dependent translocation induces phagocytosis resistance, cytotoxicity and disruption of actin microfilaments
    • Frithz-Lindsten E, Du Y, Rosqvist R and Forsberg A: Intracellular targeting of exoenzyme S of Pseudomonas aeruginosa via type III-dependent translocation induces phagocytosis resistance, cytotoxicity and disruption of actin microfilaments. Mol Microbiol 25: 1125-1139, 1997.
    • (1997) Mol Microbiol , vol.25 , pp. 1125-1139
    • Frithz-Lindsten, E.1    Du, Y.2    Rosqvist, R.3    Forsberg, A.4
  • 60
    • 0032931551 scopus 로고    scopus 로고
    • The amino-terminal domain of Pseudomonas aeruginosa ExoS disrupts actin filaments via small-molecular-weight GTP-binding proteins
    • Pederson KJ, Vallis AJ, Aktories K, Frank DW and Barbieri JT: The amino-terminal domain of Pseudomonas aeruginosa ExoS disrupts actin filaments via small-molecular-weight GTP-binding proteins. Mol Microbiol 32: 393-401, 1999.
    • (1999) Mol Microbiol , vol.32 , pp. 393-401
    • Pederson, K.J.1    Vallis, A.J.2    Aktories, K.3    Frank, D.W.4    Barbieri, J.T.5
  • 61
    • 0033796738 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa ExoT is a Rho GTPasee-activating protein
    • Krall R, Schmidt G, Aktories K and Barbieri JT: Pseudomonas aeruginosa ExoT is a Rho GTPasee-activating protein. Infect Immun 68: 6066-6068, 2000.
    • (2000) Infect Immun , vol.68 , pp. 6066-6068
    • Krall, R.1    Schmidt, G.2    Aktories, K.3    Barbieri, J.T.4
  • 62
    • 0037370212 scopus 로고    scopus 로고
    • Mice lacking inducible nitric oxide synthase show strong resistance to anti- Fas antibody-induces fulminant hepatitis
    • Chang B, Nishikawa M, Sato E and Inoue M: Mice lacking inducible nitric oxide synthase show strong resistance to anti- Fas antibody-induces fulminant hepatitis. Arch Biochem Biphys 411: 63-72, 2003.
    • (2003) Arch Biochem Biphys , vol.411 , pp. 63-72
    • Chang, B.1    Nishikawa, M.2    Sato, E.3    Inoue, M.4
  • 64
    • 0029883785 scopus 로고    scopus 로고
    • Nitric oxide induces upregulation of Fas and apoptosis in vascular smooth muscle
    • Fukuo K, Hata S, Suhara T, Nakahashi T, Shinto Y and Tsujimoto Y: Nitric oxide induces upregulation of Fas and apoptosis in vascular smooth muscle. Hypertension 27: 823-831, 1996.
    • (1996) Hypertension , vol.27 , pp. 823-831
    • Fukuo, K.1    Hata, S.2    Suhara, T.3    Nakahashi, T.4    Shinto, Y.5    Tsujimoto, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.