Crystal structure analysis of EstA from Arthrobacter sp. Rue61a - An insight into catalytic promiscuity

FEBS Letters

Volumn 588, Issue 7, 2014, Pages 1154-1160

  Wagner, Ulrike Gabriella ^a   Dimaio, Frank ^b   Kolkenbrock, Stephan ^c   Fetzner, Susanne ^c  

^a UNIVERSITY OF GRAZ   (Austria)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Catalytic promiscuity; Crystal structure; Esterase; Steric hindrance; Lactamase

Indexed keywords

BETA LACTAM; BETA LACTAMASE; CARBOXYLESTERASE; ESTA PROTEIN; ESTB PROTEIN; ESTERASE; ESTU1 PROTEIN; UNCLASSIFIED DRUG;

ARTHROBACTER; ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME STRUCTURE; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ALIGNMENT; STEREOSPECIFICITY;

ARTHROBACTER SP.;

CATALYTIC PROMISCUITY; CRYSTAL STRUCTURE; ESTERASE; STERIC HINDRANCE; Β-LACTAMASE;

AMINO ACID SEQUENCE; ARTHROBACTER; BACTERIAL PROTEINS; BETA-LACTAMASES; CARBOXYLIC ESTER HYDROLASES; CATALYTIC DOMAIN; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; MOLECULAR DOCKING SIMULATION; MOLECULAR SEQUENCE DATA; PENICILLINS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; STRUCTURAL HOMOLOGY, PROTEIN; SUBSTRATE SPECIFICITY;

EID: 84897064424     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2014.02.045     Document Type: Article

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