-
1
-
-
84863889195
-
Identifying mechanism-of-action targets for drugs and probes
-
Gregori-Puigjané E, Setola V, Hert J, Crews BA, Irwin JJ, Lounkine E, et al. Identifying mechanism-of-action targets for drugs and probes. Proc Natl Acad Sci U S A 2012; 109: 11178-11183.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 11178-11183
-
-
Gregori-Puigjané, E.1
Setola, V.2
Hert, J.3
Crews, B.A.4
Irwin, J.J.5
Lounkine, E.6
-
3
-
-
0346102501
-
Nefopam, a nonsedative benzoxazocine analgesic, selectively reduces the shivering threshold in unanesthetized subjects
-
Alfonsi P, Adam F, Passard A, Guignard B, Sessler DI, Chauvin M. Nefopam, a nonsedative benzoxazocine analgesic, selectively reduces the shivering threshold in unanesthetized subjects. Anesthesiology 2004; 100: 37-43.
-
(2004)
Anesthesiology
, vol.100
, pp. 37-43
-
-
Alfonsi, P.1
Adam, F.2
Passard, A.3
Guignard, B.4
Sessler, D.I.5
Chauvin, M.6
-
4
-
-
0019222051
-
Nefopam: a review of its pharmacological properties and therapeutic efficacy
-
Heel RC, Brogden RN, Pakes GE, Speight TM, Avery GS. Nefopam: a review of its pharmacological properties and therapeutic efficacy. Drugs 1980; 19: 249-67.
-
(1980)
Drugs
, vol.19
, pp. 249-267
-
-
Heel, R.C.1
Brogden, R.N.2
Pakes, G.E.3
Speight, T.M.4
Avery, G.S.5
-
5
-
-
84859851597
-
Compartmental pharmacokinetics of nefopam during mild hypothermia
-
Podranski T, Bouillon TW, Riva T, Kurz AM, Oehmke MJ. Compartmental pharmacokinetics of nefopam during mild hypothermia. Br J Anaesth 2012; 108: 784-91.
-
(2012)
Br J Anaesth
, vol.108
, pp. 784-791
-
-
Podranski, T.1
Bouillon, T.W.2
Riva, T.3
Kurz, A.M.4
Oehmke, M.J.5
-
6
-
-
0014578272
-
Studies on the peripheral pharmacology of fenazoxine, a potential antidepressant drug
-
Bassett JR, Cairncross KD, Hacket NB, Story M. Studies on the peripheral pharmacology of fenazoxine, a potential antidepressant drug. Br J Pharmacol 1969; 37: 69-78.
-
(1969)
Br J Pharmacol
, vol.37
, pp. 69-78
-
-
Bassett, J.R.1
Cairncross, K.D.2
Hacket, N.B.3
Story, M.4
-
7
-
-
0015335602
-
Nefopam hydrochloride: a novel muscle relaxant
-
Tobin WE, Gold RH. Nefopam hydrochloride: a novel muscle relaxant. J Clin Pharmacol New Drugs 1972; 12: 230-8.
-
(1972)
J Clin Pharmacol New Drugs
, vol.12
, pp. 230-238
-
-
Tobin, W.E.1
Gold, R.H.2
-
8
-
-
0016197948
-
Stereoselective demethylation of the enantiomers of nefopam, an experimental antidepressant and skeletal muscle relaxant
-
Bolt AG, Graham G, Wilson P. Stereoselective demethylation of the enantiomers of nefopam, an experimental antidepressant and skeletal muscle relaxant. Xenobiotica 1974; 4: 355-63.
-
(1974)
Xenobiotica
, vol.4
, pp. 355-363
-
-
Bolt, A.G.1
Graham, G.2
Wilson, P.3
-
9
-
-
0017043454
-
Molecular geometry of inhibitors of the uptake of catecholamines and serotonin in synaptosomal preparations of rat brain
-
Koe BK. Molecular geometry of inhibitors of the uptake of catecholamines and serotonin in synaptosomal preparations of rat brain. J Pharmacol Exp Ther 1976; 199: 649-61.
-
(1976)
J Pharmacol Exp Ther
, vol.199
, pp. 649-661
-
-
Koe, B.K.1
-
10
-
-
0015959188
-
Nefopam hydrochloride for pain relief
-
Cohen A. Nefopam hydrochloride for pain relief. Curr Ther Res Clin Exp 1974; 16: 184-93.
-
(1974)
Curr Ther Res Clin Exp
, vol.16
, pp. 184-193
-
-
Cohen, A.1
-
11
-
-
0016231112
-
Long-term safety of Nefopam hydrochloride (Acupan), a new analgesic formulation
-
Klotz AL. Long-term safety of Nefopam hydrochloride (Acupan), a new analgesic formulation. Curr Ther Res Clin Exp 1974; 16: 602-8.
-
(1974)
Curr Ther Res Clin Exp
, vol.16
, pp. 602-608
-
-
Klotz, A.L.1
-
12
-
-
0016255507
-
A clinical evaluation of nefopam hydrochloride (Acupan): a new analgesic
-
Workmon FC, Winter L Jr. A clinical evaluation of nefopam hydrochloride (Acupan): a new analgesic. Curr Ther Res Clin Exp 1974; 16: 609-16.
-
(1974)
Curr Ther Res Clin Exp
, vol.16
, pp. 609-616
-
-
Workmon, F.C.1
Winter Jr., L.2
-
13
-
-
0016695905
-
Further clinical evaluations of nefopam hydrochloride, a new analgesic
-
Kolodny AL, Winter L Jr. Further clinical evaluations of nefopam hydrochloride, a new analgesic. Curr Ther Res Clin Exp 1975; 17: 519-24.
-
(1975)
Curr Ther Res Clin Exp
, vol.17
, pp. 519-524
-
-
Kolodny, A.L.1
Winter Jr., L.2
-
15
-
-
0026213087
-
Action and effectiveness of nefopam chloride in the control of postoperative shivering
-
Izzo V, Mariconti P, Tiengo M. Action and effectiveness of nefopam chloride in the control of postoperative shivering. Minerva Anestesiol 1991; 57: 760-2.
-
(1991)
Minerva Anestesiol
, vol.57
, pp. 760-762
-
-
Izzo, V.1
Mariconti, P.2
Tiengo, M.3
-
16
-
-
84875757241
-
Comparison of meperidine and nefopam for prevention of shivering during spinal anesthesia
-
Kim YA, Kweon TD, Kim M, Lee HI, Lee YJ, Lee KY. Comparison of meperidine and nefopam for prevention of shivering during spinal anesthesia. Korean J Anesthesiol 2013; 64: 229-33.
-
(2013)
Korean J Anesthesiol
, vol.64
, pp. 229-233
-
-
Kim, Y.A.1
Kweon, T.D.2
Kim, M.3
Lee, H.I.4
Lee, Y.J.5
Lee, K.Y.6
-
17
-
-
84868253026
-
Efficacy spectrum of antishivering medications: meta-analysis of randomized controlled trials
-
Park SM, Mangat HS, Berger K, Rosengart AJ. Efficacy spectrum of antishivering medications: meta-analysis of randomized controlled trials. Crit Care Med 2012; 40: 3070-82.
-
(2012)
Crit Care Med
, vol.40
, pp. 3070-3082
-
-
Park, S.M.1
Mangat, H.S.2
Berger, K.3
Rosengart, A.J.4
-
18
-
-
0034727822
-
Nefopam for severe hiccups
-
Bilotta F, Rosa G. Nefopam for severe hiccups. N Engl J Med 2000; 343: 1973-4.
-
(2000)
N Engl J Med
, vol.343
, pp. 1973-1974
-
-
Bilotta, F.1
Rosa, G.2
-
19
-
-
0034758821
-
Nefopam for refractory postoperative hiccups
-
Bilotta F, Pietropaoli P, Rosa G. Nefopam for refractory postoperative hiccups. Anesth Analg 2001; 93: 1358-60.
-
(2001)
Anesth Analg
, vol.93
, pp. 1358-1360
-
-
Bilotta, F.1
Pietropaoli, P.2
Rosa, G.3
-
20
-
-
38449086050
-
Hiccup during weaning from mechanical ventilation: the use of nefopam
-
Pajot S, Geeraerts T, Leblanc PE, Duranteau J, Benhamou D. Hiccup during weaning from mechanical ventilation: the use of nefopam. Br J Anaesth 2007; 99: 748-9.
-
(2007)
Br J Anaesth
, vol.99
, pp. 748-749
-
-
Pajot, S.1
Geeraerts, T.2
Leblanc, P.E.3
Duranteau, J.4
Benhamou, D.5
-
21
-
-
84860647699
-
Tests and models of nociception and pain in rodents
-
Barrot M. Tests and models of nociception and pain in rodents. Neuroscience 2012; 211: 39-50.
-
(2012)
Neuroscience
, vol.211
, pp. 39-50
-
-
Barrot, M.1
-
23
-
-
0023223448
-
The formalin test in mice: dissociation between inflammatory and non-inflammatory pain
-
Hunskaar S, Hole K. The formalin test in mice: dissociation between inflammatory and non-inflammatory pain. Pain 1987; 30: 103-14.
-
(1987)
Pain
, vol.30
, pp. 103-114
-
-
Hunskaar, S.1
Hole, K.2
-
24
-
-
84873540379
-
Antinociceptive effect of intrathecal nefopam and interaction with morphine in formalin-induced pain of rats
-
Cho SY, Park AR, Yoon MH, Lee HG, Kim WM, Choi JI. Antinociceptive effect of intrathecal nefopam and interaction with morphine in formalin-induced pain of rats. Korean J Pain 2013; 26: 14-20.
-
(2013)
Korean J Pain
, vol.26
, pp. 14-20
-
-
Cho, S.Y.1
Park, A.R.2
Yoon, M.H.3
Lee, H.G.4
Kim, W.M.5
Choi, J.I.6
-
25
-
-
0035659279
-
Nefopam reduces thermal hypersensitivity in acute and postoperative pain models in the rat
-
Girard P, Pansart Y, Coppe MC, Gillardin JM. Nefopam reduces thermal hypersensitivity in acute and postoperative pain models in the rat. Pharmacol Res 2001; 44: 541-5.
-
(2001)
Pharmacol Res
, vol.44
, pp. 541-545
-
-
Girard, P.1
Pansart, Y.2
Coppe, M.C.3
Gillardin, J.M.4
-
26
-
-
0037134286
-
Effects of nefopam on the spinal nociceptive processes: a c-Fos protein study in the rat
-
Buritova J, Besson JM. Effects of nefopam on the spinal nociceptive processes: a c-Fos protein study in the rat. Eur J Pharmacol 2002; 441: 67-74.
-
(2002)
Eur J Pharmacol
, vol.441
, pp. 67-74
-
-
Buritova, J.1
Besson, J.M.2
-
27
-
-
67849090632
-
Long-term pain vulnerability after surgery in rats: prevention by nefopam, an analgesic with antihyperalgesic properties
-
Laboureyras E, Chateauraynaud J, Richebé P, Simonnet G. Long-term pain vulnerability after surgery in rats: prevention by nefopam, an analgesic with antihyperalgesic properties. Anesth Analg 2009; 109: 623-31.
-
(2009)
Anesth Analg
, vol.109
, pp. 623-631
-
-
Laboureyras, E.1
Chateauraynaud, J.2
Richebé, P.3
Simonnet, G.4
-
28
-
-
54249115419
-
Nefopam for the prevention of postoperative pain: quantitative systematic review
-
Evans MS, Lysakowski C, Tramèr MR. Nefopam for the prevention of postoperative pain: quantitative systematic review. Br J Anaesth 2008; 101: 610-7.
-
(2008)
Br J Anaesth
, vol.101
, pp. 610-617
-
-
Evans, M.S.1
Lysakowski, C.2
Tramèr, M.R.3
-
29
-
-
0018601327
-
Comparison of the analgesic dose-effect relationships of nefopam and oxycodone in postoperative pain
-
Tigerstedt I, Tammisto T, Leander P. Comparison of the analgesic dose-effect relationships of nefopam and oxycodone in postoperative pain. Acta Anaesthesiol Scand 1979; 23: 555-60.
-
(1979)
Acta Anaesthesiol Scand
, vol.23
, pp. 555-560
-
-
Tigerstedt, I.1
Tammisto, T.2
Leander, P.3
-
30
-
-
0028592707
-
Effect of ketorolac, ketoprofen and nefopam on platelet function
-
Dordoni PL, Della Ventura M, Stefanelli A, Iannace E, Paparella P, Rocca B, et al. Effect of ketorolac, ketoprofen and nefopam on platelet function. Anaesthesia 1994; 49: 1046-9.
-
(1994)
Anaesthesia
, vol.49
, pp. 1046-1049
-
-
Dordoni, P.L.1
Della Ventura, M.2
Stefanelli, A.3
Iannace, E.4
Paparella, P.5
Rocca, B.6
-
32
-
-
35048842029
-
Recent advances in the pharmacological management of pain
-
Guindon J, Walczak JS, Beaulieu P. Recent advances in the pharmacological management of pain. Drugs 2007; 67: 2121-33.
-
(2007)
Drugs
, vol.67
, pp. 2121-2133
-
-
Guindon, J.1
Walczak, J.S.2
Beaulieu, P.3
-
33
-
-
0037264650
-
Plasma membrane monoamine transporters: structure, regulation and function
-
Torres GE, Gainetdinov RR, Caron MG. Plasma membrane monoamine transporters: structure, regulation and function. Nat Rev Neurosci 2003; 4: 13-25.
-
(2003)
Nat Rev Neurosci
, vol.4
, pp. 13-25
-
-
Torres, G.E.1
Gainetdinov, R.R.2
Caron, M.G.3
-
34
-
-
0003032629
-
Antidepressants, muscle relaxants, and N-methyl-D-aspartate receptor antagonists
-
Bonica's management of pain. 3rd ed. Edited by Loeser JD, Bonica JJ. Philadelphia (PA), Lippincott Williams & Wilkins
-
Max MB, Gilron IH. Antidepressants, muscle relaxants, and N-methyl-D-aspartate receptor antagonists. In: Bonica's management of pain. 3rd ed. Edited by Loeser JD, Bonica JJ. Philadelphia (PA), Lippincott Williams & Wilkins. 2001, pp 1710-26.
-
(2001)
, pp. 1710-1726
-
-
Max, M.B.1
Gilron, I.H.2
-
35
-
-
17044425974
-
Nefopam inhibits calcium influx, cGMP formation, and NMDA receptor-dependent neurotoxicity following activation of voltage sensitive calcium channels
-
Novelli A, Díaz-Trelles R, Groppetti A, Fernández-Sánchez MT. Nefopam inhibits calcium influx, cGMP formation, and NMDA receptor-dependent neurotoxicity following activation of voltage sensitive calcium channels. Amino Acids 2005; 28: 183-91.
-
(2005)
Amino Acids
, vol.28
, pp. 183-191
-
-
Novelli, A.1
Díaz-Trelles, R.2
Groppetti, A.3
Fernández-Sánchez, M.T.4
-
36
-
-
2942613207
-
Nefopam blocks voltage-sensitive sodium channels and modulates glutamatergic transmission in rodents
-
Verleye M, André N, Heulard I, Gillardin JM. Nefopam blocks voltage-sensitive sodium channels and modulates glutamatergic transmission in rodents. Brain Res 2004; 1013: 249-55.
-
(2004)
Brain Res
, vol.1013
, pp. 249-255
-
-
Verleye, M.1
André, N.2
Heulard, I.3
Gillardin, J.M.4
-
37
-
-
0038045088
-
Neuronal sensitization and its behavioral correlates in a rat model of neuropathy are prevented by a cyclic analog of orphenadrine
-
Biella GE, Groppetti A, Novelli A, Fernández-Sánchez MT, Manfredi B, Sotgiu ML. Neuronal sensitization and its behavioral correlates in a rat model of neuropathy are prevented by a cyclic analog of orphenadrine. J Neurotrauma 2003; 20: 593-601.
-
(2003)
J Neurotrauma
, vol.20
, pp. 593-601
-
-
Biella, G.E.1
Groppetti, A.2
Novelli, A.3
Fernández-Sánchez, M.T.4
Manfredi, B.5
Sotgiu, M.L.6
-
38
-
-
34147165503
-
Nefopam is more potent than carbamazepine for neuroprotection against veratridine in vitro and has anticonvulsant properties against both electrical and chemical stimulation
-
Novelli A, Groppetti A, Rossoni G, Manfredi B, Ferrero- Gutiérrez A, Pérez-Gómez A, et al. Nefopam is more potent than carbamazepine for neuroprotection against veratridine in vitro and has anticonvulsant properties against both electrical and chemical stimulation. Amino Acids 2007; 32: 323-32.
-
(2007)
Amino Acids
, vol.32
, pp. 323-332
-
-
Novelli, A.1
Groppetti, A.2
Rossoni, G.3
Manfredi, B.4
Ferrero-Gutiérrez, A.5
Pérez-Gómez, A.6
-
39
-
-
80051536301
-
Nefopam enhances the protective activity of antiepileptics against maximal electroshock-induced convulsions in mice
-
Czuczwar M, Czuczwar K, Cieszczyk J, Kis J, Saran T, Luszczki JJ, et al. Nefopam enhances the protective activity of antiepileptics against maximal electroshock-induced convulsions in mice. Pharmacol Rep 2011; 63: 690-6.
-
(2011)
Pharmacol Rep
, vol.63
, pp. 690-696
-
-
Czuczwar, M.1
Czuczwar, K.2
Cieszczyk, J.3
Kis, J.4
Saran, T.5
Luszczki, J.J.6
-
40
-
-
33646911656
-
New Horizons in the development of antiepileptic drugs: innovative strategies
-
Löscher W, Schmidt D. New Horizons in the development of antiepileptic drugs: innovative strategies. Epilepsy Res 2006; 69: 183-272.
-
(2006)
Epilepsy Res
, vol.69
, pp. 183-272
-
-
Löscher, W.1
Schmidt, D.2
-
41
-
-
0024951451
-
Microdialysis studies of brain norepinephrine, serotonin, and dopamine release during ingestive behavior. Theoretical and clinical implications
-
Hoebel BG, Hernandez L, Schwartz DH, Mark GP, Hunter GA. Microdialysis studies of brain norepinephrine, serotonin, and dopamine release during ingestive behavior. Theoretical and clinical implications. Ann N Y Acad Sci 1989; 575: 171-91.
-
(1989)
Ann N Y Acad Sci
, vol.575
, pp. 171-191
-
-
Hoebel, B.G.1
Hernandez, L.2
Schwartz, D.H.3
Mark, G.P.4
Hunter, G.A.5
-
42
-
-
0028183017
-
International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin)
-
Hoyer D, Clarke DE, Fozard JR, Hartig PR, Martin GR, Mylecharane EJ, et al. International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin). Pharmacol Rev 1994; 46: 157-203.
-
(1994)
Pharmacol Rev
, vol.46
, pp. 157-203
-
-
Hoyer, D.1
Clarke, D.E.2
Fozard, J.R.3
Hartig, P.R.4
Martin, G.R.5
Mylecharane, E.J.6
-
43
-
-
37549064027
-
5-HT receptor regulation of neurotransmitter release
-
Fink KB, Göthert M. 5-HT receptor regulation of neurotransmitter release. Pharmacol Rev 2007; 59: 360-417.
-
(2007)
Pharmacol Rev
, vol.59
, pp. 360-417
-
-
Fink, K.B.1
Göthert, M.2
-
44
-
-
0032970989
-
A review of central 5-HT receptors and their function
-
Barnes NM, Sharp T. A review of central 5-HT receptors and their function. Neuropharmacology 1999; 38: 1083-152.
-
(1999)
Neuropharmacology
, vol.38
, pp. 1083-1152
-
-
Barnes, N.M.1
Sharp, T.2
-
45
-
-
70349440715
-
Preclinical and early clinical investigations related to monoaminergic pain modulation
-
Bannister K, Bee LA, Dickenson AH. Preclinical and early clinical investigations related to monoaminergic pain modulation. Neurotherapeutics 2009; 6: 703-12.
-
(2009)
Neurotherapeutics
, vol.6
, pp. 703-712
-
-
Bannister, K.1
Bee, L.A.2
Dickenson, A.H.3
-
46
-
-
84855841418
-
Protein-protein interactions at the adrenergic receptors
-
Cotecchia S, Stanasila L, Diviani D. Protein-protein interactions at the adrenergic receptors. Curr Drug Targets 2012; 13: 15-27.
-
(2012)
Curr Drug Targets
, vol.13
, pp. 15-27
-
-
Cotecchia, S.1
Stanasila, L.2
Diviani, D.3
-
47
-
-
2442467014
-
The neurobiology of dopamine signaling
-
Girault JA, Greengard P. The neurobiology of dopamine signaling. Arch Neurol 2004; 61: 641-4.
-
(2004)
Arch Neurol
, vol.61
, pp. 641-644
-
-
Girault, J.A.1
Greengard, P.2
-
48
-
-
33644833445
-
The neuropathic pain scales
-
Benzon HT. The neuropathic pain scales. Reg Anesth Pain Med 2005; 30: 417-21.
-
(2005)
Reg Anesth Pain Med
, vol.30
, pp. 417-421
-
-
Benzon, H.T.1
-
49
-
-
0034053004
-
Nefopam enantiomers: preclinical pharmacology/ toxicology and pharmacokinetic characteristics in healthy subjects after intravenous administration
-
Mather GG, Labroo R, Le Guern ME, Lepage F, Gillardin JM, Levy RH. Nefopam enantiomers: preclinical pharmacology/ toxicology and pharmacokinetic characteristics in healthy subjects after intravenous administration. Chirality 2000; 12: 153-9.
-
(2000)
Chirality
, vol.12
, pp. 153-159
-
-
Mather, G.G.1
Labroo, R.2
Le Guern, M.E.3
Lepage, F.4
Gillardin, J.M.5
Levy, R.H.6
-
50
-
-
34548658623
-
French Network of Pharmacovigilance Centers. Overview of adverse reactions to nefopam: an analysis of the French Pharmacovigilance database
-
Durrieu G, Olivier P, Bagheri H, Montastruc JL; French Network of Pharmacovigilance Centers. Overview of adverse reactions to nefopam: an analysis of the French Pharmacovigilance database. Fundam Clin Pharmacol 2007; 21: 555-8.
-
(2007)
Fundam Clin Pharmacol
, vol.21
, pp. 555-558
-
-
Durrieu, G.1
Olivier, P.2
Bagheri, H.3
Montastruc, J.L.4
|