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Volumn 32, Issue 3, 2007, Pages 323-332

Nefopam is more potent than carbamazepine for neuroprotection against veratridine in vitro and has anticonvulsant properties against both electrical and chemical stimulation

Author keywords

Behaviour; Carbamazepine; Cultured cerebellar neurons; Nefopam; Seizures

Indexed keywords

ANTICONVULSIVE AGENT; CALCIUM CHANNEL L TYPE; CARBAMAZEPINE; DIAZEPAM; GLUTAMIC ACID; ISONIAZID; NEFOPAM; NEUROPROTECTIVE AGENT; VERATRIDINE;

EID: 34147165503     PISSN: 09394451     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00726-006-0419-6     Document Type: Article
Times cited : (19)

References (52)
  • 1
    • 17044399816 scopus 로고    scopus 로고
    • Lamotrigine, carbamazepine and phenytoin differentially alter extracellular levels of 5-hydroxytryptamine, dopamine and amino acids
    • S Ahmad LJ Fowler PS Whitton 2005 Lamotrigine, carbamazepine and phenytoin differentially alter extracellular levels of 5-hydroxytryptamine, dopamine and amino acids Epilepsy Res 63 141 149
    • (2005) Epilepsy Res , vol.63 , pp. 141-149
    • Ahmad, S.1    Fowler, L.J.2    Whitton, P.S.3
  • 2
    • 0346102501 scopus 로고    scopus 로고
    • Nefopam, a nonsedative benzoxazocine analgesic, selectively reduces the shivering threshold in unanesthetized subjects
    • P Alfonsi F Adam A Passard B Guignard DI Sessler M Chauvin 2004 Nefopam, a nonsedative benzoxazocine analgesic, selectively reduces the shivering threshold in unanesthetized subjects Anesthesiology 100 37 43
    • (2004) Anesthesiology , vol.100 , pp. 37-43
    • Alfonsi, P.1    Adam, F.2    Passard, A.3    Guignard, B.4    Sessler, D.I.5    Chauvin, M.6
  • 5
    • 0026729753 scopus 로고
    • Effects of benzodiazepine receptor ligands with different intrinsic activities on seizures induced by inhibition of GAD
    • R Bernasconi P Martin AF Steulet C Portet T Leonhardt M Schmutz 1992 Effects of benzodiazepine receptor ligands with different intrinsic activities on seizures induced by inhibition of GAD Epilepsy Res Suppl 8 87 96
    • (1992) Epilepsy Res , vol.8 , pp. 87-96
    • Bernasconi, R.1    Martin, P.2    Steulet, A.F.3    Portet, C.4    Leonhardt, T.5    Schmutz, M.6
  • 6
    • 0038045088 scopus 로고    scopus 로고
    • Neuronal sensitization and its behavioral correlates in a rat model of neuropathy are prevented by a cyclic analog of orphenadrine
    • GE Biella A Groppetti A Novelli MT Fernández-Sánchez B Manfredi ML Sptgiu 2003 Neuronal sensitization and its behavioral correlates in a rat model of neuropathy are prevented by a cyclic analog of orphenadrine J Neurotrauma 20 593 601
    • (2003) J Neurotrauma , vol.20 , pp. 593-601
    • Biella, G.E.1    Groppetti, A.2    Novelli, A.3    Fernández-Sánchez, M.T.4    Manfredi, B.5    Sptgiu, M.L.6
  • 7
    • 0023574096 scopus 로고
    • + channels: Local anesthetics, antiarrythmics and anticonvulsants
    • + channels: local anesthetics, antiarrythmics and anticonvulsants Trends Pharmacol Sci 8 57 65
    • (1987) Trends Pharmacol Sci , vol.8 , pp. 57-65
    • Catterall, W.A.1
  • 8
    • 0026467138 scopus 로고
    • Effects of antiepileptic drugs, calcium channel blockers and other compounds on seizures induced by activation of voltage dependent L calcium channel in DBA/2 mice
    • G De Sarro C Ascioti ED di Paola MJ Vidal A De Sarro 1992 Effects of antiepileptic drugs, calcium channel blockers and other compounds on seizures induced by activation of voltage dependent L calcium channel in DBA/2 mice Gen Pharmacol 23 1205 1216
    • (1992) Gen Pharmacol , vol.23 , pp. 1205-1216
    • De Sarro, G.1    Ascioti, C.2    Di Paola, E.D.3    Vidal, M.J.4    De Sarro, A.5
  • 9
    • 70449177837 scopus 로고
    • A note on a simple apparatus for detecting neurological deficit in rats and mice
    • NW Dunham TS Miya 1957 A note on a simple apparatus for detecting neurological deficit in rats and mice J Am Pharmaceut Assoc 46 208 209
    • (1957) J Am Pharmaceut Assoc , vol.46 , pp. 208-209
    • Dunham, N.W.1    Miya, T.S.2
  • 12
    • 0026079797 scopus 로고
    • The marine toxin okadaic acid is a potent neurotoxin for cultured cerebellar neurons
    • MT Fernández V Zitko S Gascón A Novelli 1991 The marine toxin okadaic acid is a potent neurotoxin for cultured cerebellar neurons Life Sci 49 PL157 PL162
    • (1991) Life Sci , vol.49
    • Fernández, M.T.1    Zitko, V.2    Gascón, S.3    Novelli, A.4
  • 16
    • 0027504611 scopus 로고
    • Evaluation of nefopam as a monoamine uptake inhibitor in vivo in mice
    • RW Fuller HD Snoddy 1993 Evaluation of nefopam as a monoamine uptake inhibitor in vivo in mice Neuropharmacology 32 995 999
    • (1993) Neuropharmacology , vol.32 , pp. 995-999
    • Fuller, R.W.1    Snoddy, H.D.2
  • 18
    • 0018591886 scopus 로고
    • Respiratory effect of nefopam
    • Suppl B 17
    • HU Gerbershagen E Schaffner 1979 Respiratory effect of nefopam Clin Ther 2 Suppl B 17 39 42
    • (1979) Clin Ther , vol.2 , pp. 39-42
    • Gerbershagen, H.U.1    Schaffner, E.2
  • 19
    • 0033065166 scopus 로고    scopus 로고
    • Nefopam strongly depresses the nociceptive flexion (R(III)) reflex in humans
    • F Guirimand X Dupont D Bouhassira L Brasseur M Chauvin 1999 Nefopam strongly depresses the nociceptive flexion (R(III)) reflex in humans Pain 80 399 404
    • (1999) Pain , vol.80 , pp. 399-404
    • Guirimand, F.1    Dupont, X.2    Bouhassira, D.3    Brasseur, L.4    Chauvin, M.5
  • 20
    • 0019222051 scopus 로고
    • Nefopam: A review of its pharmacological properties and therapeutic efficacy
    • RC Heel RN Brogden GE Pakes TM Speight GS Avery 1980 Nefopam: a review of its pharmacological properties and therapeutic efficacy Drugs 19 249 267
    • (1980) Drugs , vol.19 , pp. 249-267
    • Heel, R.C.1    Brogden, R.N.2    Pakes, G.E.3    Speight, T.M.4    Avery, G.S.5
  • 21
    • 0023221188 scopus 로고
    • Involvement of central serotonergic pathways in nefopam-induced antinoception
    • S Hunskaar OB Fasmer OJ Broch K Hole 1987 Involvement of central serotonergic pathways in nefopam-induced antinoception Eur J Pharmacol 138 77 82
    • (1987) Eur J Pharmacol , vol.138 , pp. 77-82
    • Hunskaar, S.1    Fasmer, O.B.2    Broch, O.J.3    Hole, K.4
  • 22
    • 0032881478 scopus 로고    scopus 로고
    • Valproate and carbamazepine increase prefrontal dopamine release by 5-HT1A receptor activation
    • J Ichikawa HY Meltzer 1999 Valproate and carbamazepine increase prefrontal dopamine release by 5-HT1A receptor activation Eur J Pharmacol 380 R1 R3
    • (1999) Eur J Pharmacol , vol.380
    • Ichikawa, J.1    Meltzer, H.Y.2
  • 23
    • 23044483242 scopus 로고    scopus 로고
    • Lithium differs from anticonvulsant mood stabilizers in prefrontal cortical and accumbal dopamine release: Role of 5-HT(1A) receptor agonism
    • J Ichikawa J Dai HY Meltzer 2005 Lithium differs from anticonvulsant mood stabilizers in prefrontal cortical and accumbal dopamine release: role of 5-HT(1A) receptor agonism Brain Res 1049 182 190
    • (2005) Brain Res , vol.1049 , pp. 182-190
    • Ichikawa, J.1    Dai, J.2    Meltzer, H.Y.3
  • 24
    • 0023145317 scopus 로고
    • A comparative assay of nefopam, morphine and d-amphetamine
    • DR Jasinski KL Preston 1987 A comparative assay of nefopam, morphine and d-amphetamine Psychopharmacology 91 273 278
    • (1987) Psychopharmacology , vol.91 , pp. 273-278
    • Jasinski, D.R.1    Preston, K.L.2
  • 25
    • 0024391789 scopus 로고
    • Photochemically generated cytosolic calcium pulses and their detection by Fluo-3
    • JPY Kao AT Harootunian RY Tsien 1989 Photochemically generated cytosolic calcium pulses and their detection by Fluo-3 J Biol Chem 264 8179 8184
    • (1989) J Biol Chem , vol.264 , pp. 8179-8184
    • Kao, J.P.Y.1    Harootunian, A.T.2    Tsien, R.Y.3
  • 26
    • 0028241312 scopus 로고
    • Antiepileptic drugs - Calcium current interaction in cultured human neuroblastoma cells
    • M Kito M Maehara K Watanabe 1994 Antiepileptic drugs - calcium current interaction in cultured human neuroblastoma cells Seizure 3 141 149
    • (1994) Seizure , vol.3 , pp. 141-149
    • Kito, M.1    Maehara, M.2    Watanabe, K.3
  • 27
    • 0036388405 scopus 로고    scopus 로고
    • Spike-and-wave complexes and seizure exacerbation caused by carbamazepine
    • S Kochen B Giagante S Oddo 2002 Spike-and-wave complexes and seizure exacerbation caused by carbamazepine Eur J Neurol 9 41 47
    • (2002) Eur J Neurol , vol.9 , pp. 41-47
    • Kochen, S.1    Giagante, B.2    Oddo, S.3
  • 28
    • 0017043454 scopus 로고
    • Molecular geometry of inhibitors of the uptake of catecholamines and serotonin in synaptosomal preparations of rat brain
    • BK Koe 1976 Molecular geometry of inhibitors of the uptake of catecholamines and serotonin in synaptosomal preparations of rat brain J Pharmacol Exp Ther 199 649 661
    • (1976) J Pharmacol Exp Ther , vol.199 , pp. 649-661
    • Koe, B.K.1
  • 29
    • 0029417266 scopus 로고
    • Orphenadrine is an uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist: Binding and patch clamp studies
    • J Kornhuber CG Parsons S Hartmann W Retz S Kamolz J Thome P Riederer 1995 Orphenadrine is an uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist: binding and patch clamp studies J Neural Transm 102 237 246
    • (1995) J Neural Transm , vol.102 , pp. 237-246
    • Kornhuber, J.1    Parsons, C.G.2    Hartmann, S.3    Retz, W.4    Kamolz, S.5    Thome, J.6    Riederer, P.7
  • 30
    • 0034053004 scopus 로고    scopus 로고
    • Nefopam enantiomers: Preclinical pharmacology/toxicology and pharmacokinetic characteristics in healthy subjects after intravenous administration
    • GG Mather R Labroo ME Le Guern F Lepage JM Gillardin RH Levy 2000 Nefopam enantiomers: preclinical pharmacology/toxicology and pharmacokinetic characteristics in healthy subjects after intravenous administration Chirality 12 153 159
    • (2000) Chirality , vol.12 , pp. 153-159
    • Mather, G.G.1    Labroo, R.2    Le Guern, M.E.3    Lepage, F.4    Gillardin, J.M.5    Levy, R.H.6
  • 32
    • 0034774938 scopus 로고    scopus 로고
    • Determination of effects of antiepileptic drugs on SNAREsmediated hippocampal monoamine release using in vivo microdialysis
    • T Murakami M Okada Y Kawata G Zhu A Kamata S Kaneko 2001 Determination of effects of antiepileptic drugs on SNAREsmediated hippocampal monoamine release using in vivo microdialysis Br J Pharmacol 134 507 520
    • (2001) Br J Pharmacol , vol.134 , pp. 507-520
    • Murakami, T.1    Okada, M.2    Kawata, Y.3    Zhu, G.4    Kamata, A.5    Kaneko, S.6
  • 33
    • 0023895734 scopus 로고
    • Glutamate becomes neurotoxic via the NMDA receptor when intracellular energy levels are reduced
    • A Novelli JA Reilly PG Lypsko RC Henneberry 1988 Glutamate becomes neurotoxic via the NMDA receptor when intracellular energy levels are reduced Brain Res 451 205 212
    • (1988) Brain Res , vol.451 , pp. 205-212
    • Novelli, A.1    Reilly, J.A.2    Lypsko, P.G.3    Henneberry, R.C.4
  • 34
    • 17044425974 scopus 로고    scopus 로고
    • Nefopam inhibits calcium influx, cGMP formation, and NMDA receptor-dependent neurotoxicity following activation of voltage sensitive calcium channels
    • A Novelli R Díaz-Trelles A Groppetti MT Fernández- Sánchez 2006 Nefopam inhibits calcium influx, cGMP formation, and NMDA receptor-dependent neurotoxicity following activation of voltage sensitive calcium channels Amino Acids 30 183 191
    • (2006) Amino Acids , vol.30 , pp. 183-191
    • Novelli, A.1    Díaz-Trelles, R.2    Groppetti, A.3    Fernández- Sánchez, M.T.4
  • 35
    • 0028826528 scopus 로고
    • Adverse reactions associated with nefopam
    • PI Pillans DJ Woods 1995 Adverse reactions associated with nefopam NZ Med J 108 382 384
    • (1995) NZ Med J , vol.108 , pp. 382-384
    • Pillans, P.I.1    Woods, D.J.2
  • 38
    • 0025183507 scopus 로고
    • The effect of nefopam and its enantiomers on the uptake of 5-hydroxytryptamine, noradrenaline and dopamine in crude rat brain synaptosomal preparations
    • JH Rosland K Hole 1990 The effect of nefopam and its enantiomers on the uptake of 5-hydroxytryptamine, noradrenaline and dopamine in crude rat brain synaptosomal preparations J Pharm Pharmacol 42 437 438
    • (1990) J Pharm Pharmacol , vol.42 , pp. 437-438
    • Rosland, J.H.1    Hole, K.2
  • 39
    • 0027234636 scopus 로고
    • Effects of carbamazepine on action potentials and calcium currents in rat spinal ganglion cells in vitro
    • K Schirrmacher A Mayer J Walden R Dusing D Bingmann 1993 Effects of carbamazepine on action potentials and calcium currents in rat spinal ganglion cells in vitro Neuropsychobiology 27 176 179
    • (1993) Neuropsychobiology , vol.27 , pp. 176-179
    • Schirrmacher, K.1    Mayer, A.2    Walden, J.3    Dusing, R.4    Bingmann, D.5
  • 40
    • 0031946435 scopus 로고    scopus 로고
    • Effects of phenytoin, carbamazepine, and gabapentin on calcium channels in hippocampal granule cells from patients with temporal lobe epilepsy
    • TB Schumacher H Beck C Steinhauser J Schramm CE Elger 1998 Effects of phenytoin, carbamazepine, and gabapentin on calcium channels in hippocampal granule cells from patients with temporal lobe epilepsy Epilepsia 39 355 363
    • (1998) Epilepsia , vol.39 , pp. 355-363
    • Schumacher, T.B.1    Beck, H.2    Steinhauser, C.3    Schramm, J.4    Elger, C.E.5
  • 41
    • 0026562113 scopus 로고
    • i in cultured rat hippocampal neurons following exposure to N-methyl-D-aspartate
    • i in cultured rat hippocampal neurons following exposure to N-methyl-D-aspartate J Physiol 448 655 676
    • (1992) J Physiol , vol.448 , pp. 655-676
    • Segal, M.1    Manor, D.2
  • 42
    • 0027004985 scopus 로고
    • Pharmacology of gamma-aminobutyric acid. a receptor complex after the in vivo administration of the anxioselective and anticonvulsant beta-carboline derivative abecarnil
    • M Serra MC Foddi CA Ghiani MA Melis C Motzo A Concas E Sanna G Biggio 1992 Pharmacology of gamma-aminobutyric acid. A receptor complex after the in vivo administration of the anxioselective and anticonvulsant beta-carboline derivative abecarnil J Pharmacol Exp Ther 263 1360 1368
    • (1992) J Pharmacol Exp Ther , vol.263 , pp. 1360-1368
    • Serra, M.1    Foddi, M.C.2    Ghiani, C.A.3    Melis, M.A.4    Motzo, C.5    Concas, A.6    Sanna, E.7    Biggio, G.8
  • 43
    • 0030848858 scopus 로고    scopus 로고
    • Voltage-activated calcium channels: Targets of antiepileptic drug therapy?
    • A Stefani F Spadoni G Bernardi 1997 Voltage-activated calcium channels: targets of antiepileptic drug therapy? Epilepsia 38 959 965
    • (1997) Epilepsia , vol.38 , pp. 959-965
    • Stefani, A.1    Spadoni, F.2    Bernardi, G.3
  • 45
    • 0000013415 scopus 로고
    • Some neurophysiological and neuropharmacological characteristics of audiogenic seizure susceptible mice
    • EA Swinyard AN Castellion GB Fink LS Goodman 1963 Some neurophysiological and neuropharmacological characteristics of audiogenic seizure susceptible mice J Pharmacol Exp Ther 140 375 384
    • (1963) J Pharmacol Exp Ther , vol.140 , pp. 375-384
    • Swinyard, E.A.1    Castellion, A.N.2    Fink, G.B.3    Goodman, L.S.4
  • 46
    • 0015335602 scopus 로고
    • Nefopam hydrochloride: A novel muscle relaxant
    • WE Tobin RH Gold 1972 Nefopam hydrochloride: a novel muscle relaxant J Clin Pharmacol New Drugs 12 230 238
    • (1972) J Clin Pharmacol New Drugs , vol.12 , pp. 230-238
    • Tobin, W.E.1    Gold, R.H.2
  • 48
    • 2942613207 scopus 로고    scopus 로고
    • Nefopam blocks voltage-sensitive sodium channels and modulates glutamatergic transmission in rodents
    • M Verleye N André I Heulard J-M Gillardin 2004 Nefopam blocks voltage-sensitive sodium channels and modulates glutamatergic transmission in rodents Brain Res 1013 249 255
    • (2004) Brain Res , vol.1013 , pp. 249-255
    • Verleye, M.1    André, N.2    Heulard, I.3    Gillardin, J.-M.4
  • 51
    • 0020334077 scopus 로고
    • Inhibition of binding of [3H] batrachotoxinin a 20-a-benzoate to sodium channels by the anticonvulsant drugs dyphenylhydantoin and carbamazepine
    • M Willow WA Catterall 1982 Inhibition of binding of [3H] batrachotoxinin A 20-a-benzoate to sodium channels by the anticonvulsant drugs dyphenylhydantoin and carbamazepine Mol Pharmacol 22 627 635
    • (1982) Mol Pharmacol , vol.22 , pp. 627-635
    • Willow, M.1    Catterall, W.A.2


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