CSF-1 receptor-mediated differentiation of a new type of monocytic cell with B cell-stimulating activity: Its selective dependence on IL-34

Journal of Leukocyte Biology

Volumn 95, Issue 1, 2014, Pages 19-31

  Yamane, Fumihiro ^a   Nishikawa, Yumiko ^a,d   Matsui, Kazue ^a   Asakura, Miki ^a   Iwasaki, Eriko ^a   Watanabe, Koji ^a   Tanimoto, Hikaru ^a   Sano, Hiroki ^a   Fujiwara, Yuki ^a   Richard Stanley, E ^b   Kanayama, Naoki ^a   Mabbott, Neil A ^c   Magari, Masaki ^a   Ohmori, Hitoshi ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

CD11b; Follicular dendritic cells; Mouse spleen

Indexed keywords

CD11B ANTIGEN; CD40 ANTIGEN; COLONY STIMULATING FACTOR 1; CYTOKINE; INTERLEUKIN 13; INTERLEUKIN 15; INTERLEUKIN 2; INTERLEUKIN 21; INTERLEUKIN 34; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 7; MESSENGER RNA; MUCOSAL ADDRESSIN CELL ADHESION MOLECULE 1; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG; COLONY STIMULATING FACTOR RECEPTOR; INTERLEUKIN 34, MOUSE; INTERLEUKIN DERIVATIVE; INTERLEUKIN-34, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; B LYMPHOCYTE; BIOLOGICAL FUNCTIONS; CELL DIFFERENTIATION; CELL STRUCTURE; CONTROLLED STUDY; CULTURE MEDIUM; GENE EXPRESSION; GENE EXPRESSION PROFILING; MACROPHAGE; MONOCYTE; MONONUCLEAR CELL; MONONUCLEAR PHAGOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; WESTERN BLOTTING; ANIMAL; CD11B; CELL LINE; COCULTURE; CYTOLOGY; FOLLICULAR DENDRITIC CELLS; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETICS; IMMUNOLOGY; IMMUNOPHENOTYPING; KNOCKOUT MOUSE; MALE; METABOLISM; MOUSE SPLEEN; PHAGOCYTE; RNA INTERFERENCE; SPLEEN; STEM CELL;

CD11B; FOLLICULAR DENDRITIC CELLS; MOUSE SPLEEN;

ANIMALS; B-LYMPHOCYTES; CELL DIFFERENTIATION; CELL LINE; COCULTURE TECHNIQUES; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; IMMUNOPHENOTYPING; INTERLEUKINS; MALE; MICE; MICE, KNOCKOUT; MONOCYTES; PHAGOCYTES; RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR; RNA INTERFERENCE; SPLEEN; STEM CELLS;

EID: 84897018686     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.0613311     Document Type: Article

References (52)

1. Vinuesa, C. G., Sanz, I., Cook, M. C. (2009) Dysregulation of germinal centres in autoimmune disease. Nat. Rev. Immunol. 9, 845-857.
2. Rajewsky, K. (1996) Clonal selection and learning in the antibody system. Nature 381, 751-758.
3. Liu, M., Schatz, D. G. (2009) Balancing AID and DNA repair during somatic hypermutation. Trends Immunol. 30, 173-181.
4. Allen, C. D., Cyster, J. G. (2008) Follicular dendritic cell networks of primary follicles and germinal centers: phenotype and function. Semin. Immunol. 20, 14-25.
5. Kosco-Vilbois, M. H. (2003) Are follicular dendritic cells really good for nothing? Nat. Rev. Immunol. 3, 764-769.
6. Klein, U., Dalla-Favera, R. (2008) Germinal centres: role in B-cell physiology and malignancy. Nat. Rev. Immunol. 8, 22-33.
7. Park, C. S., Choi, Y. S. (2005) How do follicular dendritic cells interact intimately with B cells in the germinal centre? Immunology 114, 2-10.
8. Nishikawa, Y., Hikida, M., Magari, M., Kanayama, N., Mori, M., Kitamura, H., Kurosaki, T., Ohmori, H. (2006) Establishment of lymphotoxin β receptor signaling-dependent cell lines with follicular dendritic cell phenotypes from mouse lymph nodes. J. Immunol. 177, 5204-5214.
9. Mabbott, N. A., Kenneth Baillie, J., Kobayashi, A., Donaldson, D. S., Ohmori, H., Yoon, S. O., Freedman, A. S., Freeman, T. C., Summers, K. M. (2011) Expression of mesenchyme-specific gene signatures by follicular dendritic cells: insights from the meta-analysis of microarray data from multiple mouse cell populations. Immunology 133, 482-498.
10. Mackay, F., Browning, J. L. (1998) Turning off follicular dendritic cells. Nature 395, 26-27.
11. Endres, R., Alimzhanov, M. B., Plitz, T., Futterer, A., Kosco-Vilbois, M. H., Nedospasov, S. A., Rajewsky, K., Pfeffer, K. (1999) Mature follicular dendritic cell networks depend on expression of lymphotoxin β receptor by radioresistant stromal cells and of lymphotoxin β and tumor necrosis factor by B cells. J. Exp. Med. 189, 159-168.
12. Magari, M., Nishikawa, Y., Fujii, Y., Nishio, Y., Watanabe, K., Fujiwara, M., Kanayama, N., Ohmori, H. (2011) IL-21-dependent B cell death driven by prostaglandin E2, a product secreted from follicular dendritic cells. J. Immunol. 187, 4210-4218.
13. Dai, X. M., Ryan, G. R., Hapel, A. J., Dominguez, M. G., Russell, R. G., Kapp, S., Sylvestre, V., Stanley, E. R. (2002) Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects. Blood 99, 111-120.
14. Lin, H., Lee, E., Hestir, K., Leo, C., Huang, M., Bosch, E., Halenbeck, R., Wu, G., Zhou, A., Behrens, D., Hollenbaugh, D., Linnemann, T., Qin, M., Wong, J., Chu, K., Doberstein, S. K., Williams, L. T. (2008) Discovery of a cytokine and its receptor by functional screening of the extracellular proteome. Science 320, 807-811.
15. Garceau, V., Smith, J., Paton, I. R., Davey, M., Fares, M. A., Sester, D. P., Burt, D. W., Hume, D. A. (2010) Pivotal Advance: Avian colony-stimulating factor 1 (CSF-1), interleukin-34 (IL-34), and CSF-1 receptor genes and gene products. J. Leukoc. Biol. 87, 753-764.
16. Hamilton, J. A., Achuthan, A. (2013) Colony stimulating factors and myeloid cell biology in health and disease. Trends Immunol. 34, 81-89.
17. Hume, D. A. (2008) Macrophages as APC and the dendritic cell myth. J. Immunol. 181, 5829-5835.
18. Wei, S., Nandi, S., Chitu, V., Yeung, Y. G., Yu, W., Huang, M., Williams, L. T., Lin, H., Stanley, E. R. (2010) Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells. J. Leukoc. Biol. 88, 495-505.
19. Zelante, T., Ricciardi-Castagnoli, P. (2012) The yin-yang nature of CSF1R-binding cytokines. Nat. Immunol. 13, 717-719.
20. Droin, N., Solary, E. (2010) Editorial: CSF1R, CSF-1, and IL-34, a "menage a trois" conserved across vertebrates. J. Leukoc. Biol. 87, 745-747.
21. Wang, Y., Szretter, K. J., Vermi, W., Gilfillan, S., Rossini, C., Cella, M., Barrow, A. D., Diamond, M. S., Colonna, M. (2012) IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia. Nat. Immunol. 13, 753-760.
22. Greter, M., Lelios, I., Pelczar, P., Hoeffel, G., Price, J., Leboeuf, M., Kundig, T. M., Frei, K., Ginhoux, F., Merad, M., Becher, B. (2012) Stroma-derived interleukin-34 controls the development and maintenance of Langerhans cells and the maintenance of microglia. Immunity 37, 1050-1060.
23. Ginhoux, F., Tacke, F., Angeli, V., Bogunovic, M., Loubeau, M., Dai, X. M., Stanley, E. R., Randolph, G. J., Merad, M. (2006) Langerhans cells arise from monocytes in vivo. Nat. Immunol. 7, 265-273.
24. Witmer-Pack, M. D., Hughes, D. A., Schuler, G., Lawson, L., McWilliam, A., Inaba, K., Steinman, R. M., Gordon, S. (1993) Identification of macrophages and dendritic cells in the osteopetrotic (op/op) mouse. J. Cell Sci. 104, 1021-1029.
25. Gabrilovich, D. I., Nagaraj, S. (2009) Myeloid-derived suppressor cells as regulators of the immune system. Nat. Rev. Immunol. 9, 162-174.
26. Freeman, T. C., Goldovsky, L., Brosch, M., van Dongen, S., Maziere, P., Grocock, R. J., Freilich, S., Thornton, J., Enright, A. J. (2007) Construction, visualisation, and clustering of transcription networks from microarray expression data. PLoS Comput. Biol. 3, 2032-2042.
27. Mabbott, N. A., Kenneth Baillie, J., Hume, D. A., Freeman, T. C. (2010) Meta-analysis of lineage-specific gene expression signatures in mouse leukocyte populations. Immunobiology 215, 724-736.
28. Hume, D. A., Summers, K. M., Raza, S., Baillie, J. K., Freeman, T. C. (2010) Functional clustering and lineage markers: insights into cellular differentiation and gene function from large-scale microarray studies of purified primary cell populations. Genomics 95, 328-338.
29. Labeur, M. S., Roters, B., Pers, B., Mehling, A., Luger, T. A., Schwarz, T., Grabbe, S. (1999) Generation of tumor immunity by bone marrowderived dendritic cells correlates with dendritic cell maturation stage. J. Immunol. 162, 168-175.
30. Geissmann, F., Manz, M. G., Jung, S., Sieweke, M. H., Merad, M., Ley, K. (2010) Development of monocytes, macrophages, and dendritic cells. Science 327, 656-661.
31. Geissmann, F., Jung, S., Littman, D. R. (2003) Blood monocytes consist of two principal subsets with distinct migratory properties. Immunity 19, 71-82.
32. Bronte, V., Apolloni, E., Cabrelle, A., Ronca, R., Serafini, P., Zamboni, P., Restifo, N. P., Zanovello, P. (2000) Identification of a CD11b(+)/Gr-1(+)/CD31(+) myeloid progenitor capable of activating or suppressing CD8(+) T cells. Blood 96, 3838-3846.
33. Hume, D. A., Mabbott, N., Raza, S., Freeman, T. C. (2013) Can DCs be distinguished from macrophages by molecular signatures? Nat. Immunol. 14, 187-189.
34. Nandi, S., Akhter, M. P., Seifert, M. F., Dai, X. M., Stanley, E. R. (2006) Developmental and functional significance of the CSF-1 proteoglycan chondroitin sulfate chain. Blood 107, 786-795.
35. Pixley, F. J., Stanley, E. R. (2004) CSF-1 regulation of the wandering macrophage: complexity in action. Trends Cell Biol. 14, 628-638.
36. Stein, J., Borzillo, G. V., Rettenmier, C. W. (1990) Direct stimulation of cells expressing receptors for macrophage colony-stimulating factor (CSF-1) by a plasma membrane-bound precursor of human CSF-1. Blood 76, 1308-1314.
37. Youn, J. I., Nagaraj, S., Collazo, M., Gabrilovich, D. I. (2008) Subsets of myeloid-derived suppressor cells in tumor-bearing mice. J. Immunol. 181, 5791-5802.
38. Watanabe, S., Deguchi, K., Zheng, R., Tamai, H., Wang, L. X., Cohen, P. A., Shu, S. (2008) Tumor-induced CD11b+Gr-1+ myeloid cells suppress T cell sensitization in tumor-draining lymph nodes. J. Immunol. 181, 3291-3300.
39. Zhang, M., Tang, H., Guo, Z., An, H., Zhu, X., Song, W., Guo, J., Huang, X., Chen, T., Wang, J., Cao, X. (2004) Splenic stroma drives mature dendritic cells to differentiate into regulatory dendritic cells. Nat. Immunol. 5, 1124-1133.
40. Svensson, M., Maroof, A., Ato, M., Kaye, P. M. (2004) Stromal cells direct local differentiation of regulatory dendritic cells. Immunity 21, 805-816.
41. Zhu, B., Bando, Y., Xiao, S., Yang, K., Anderson, A. C., Kuchroo, V. K., Khoury, S. J. (2007) CD11b+Ly-6C(hi) suppressive monocytes in experimental autoimmune encephalomyelitis. J. Immunol. 179, 5228-5237.
42. Dunay, I. R., Damatta, R. A., Fux, B., Presti, R., Greco, S., Colonna, M., Sibley, L. D. (2008) Gr1(+) inflammatory monocytes are required for mucosal resistance to the pathogen Toxoplasma gondii. Immunity 29, 306-317.
43. Delano, M. J., Scumpia, P. O., Weinstein, J. S., Coco, D., Nagaraj, S., Kelly-Scumpia, K. M., O'Malley, K. A., Wynn, J. L., Antonenko, S., Al-Quran, S. Z., Swan, R., Chung, C. S., Atkinson, M. A., Ramphal, R., Gabrilovich, D. I., Reeves, W. H., Ayala, A., Phillips, J., Laface, D., Heyworth, P. G., Clare-Salzler, M., Moldawer, L. L. (2007) MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis. J. Exp. Med. 204, 1463-1474.
44. Jordan, M. B., Mills, D. M., Kappler, J., Marrack, P., Cambier, J. C. (2004) Promotion of B cell immune responses via an alum-induced myeloid cell population. Science 304, 1808-1810.
45. Sisson, T. H., Nguyen, M. H., Yu, B., Novak, M. L., Simon, R. H., Koh, T. J. (2009) Urokinase-type plasminogen activator increases hepatocyte growth factor activity required for skeletal muscle regeneration. Blood 114, 5052-5061.
46. Smith, H. W., Marshall, C. J. (2010) Regulation of cell signalling by uPAR. Nat. Rev. Mol. Cell. Biol. 11, 23-36.
47. Chitu, V., Stanley, E. R. (2006) Colony-stimulating factor-1 in immunity and inflammation. Curr. Opin. Immunol. 18, 39-48.
48. Nakamichi, Y., Mizoguchi, T., Arai, A., Kobayashi, Y., Sato, M., Penninger, J. M., Yasuda, H., Kato, S., DeLuca, H. F., Suda, T., Udagawa, N., Takahashi, N. (2012) Spleen serves as a reservoir of osteoclast precursors through vitamin D-induced IL-34 expression in osteopetrotic op/op mice. Proc. Natl. Acad. Sci. USA 109, 10006-10011.
49. Nandi, S., Gokhan, S., Dai, X. M., Wei, S., Enikolopov, G., Lin, H., Mehler, M. F., Stanley, E. R. (2012) The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturation. Dev. Biol. 367, 100-113.
50. Ginhoux, F., Greter, M., Leboeuf, M., Nandi, S., See, P., Gokhan, S., Mehler, M. F., Conway, S. J., Ng, L. G., Stanley, E. R., Samokhvalov, I. M., Merad, M. (2010) Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science 330, 841-845.
51. Chihara, T., Suzu, S., Hassan, R., Chutiwitoonchai, N., Hiyoshi, M., Motoyoshi, K., Kimura, F., Okada, S. (2010) IL-34 and M-CSF share the receptor Fms but are not identical in biological activity and signal activation. Cell Death Differ. 17, 1917-1927.
52. Liu, H., Leo, C., Chen, X., Wong, B. R., Williams, L. T., Lin, H., He, X. (2012) The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1. Biochim. Biophys. Acta 1824, 938-945.