Spleen serves as a reservoir of osteoclast precursors through vitamin D-induced IL-34 expression in osteopetrotic op/op mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 25, 2012, Pages 10006-10011

  Nakamichi, Yuko ^a   Mizoguchi, Toshihide ^a   Arai, Atsushi ^a   Kobayashi, Yasuhiro ^a   Sato, Masahiro ^b   Penninger, Josef M ^c   Yasuda, Hisataka ^d   Kato, Shigeaki ^e   DeLuca, Hector F ^f   Suda, Tatsuo ^g   Udagawa, Nobuyuki ^b   Takahashi, Naoyuki ^a  

^a Institute for Oral Science   (Japan)

^b MATSUMOTO DENTAL UNIVERSITY   (Japan)

^c ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

^d Oriental Yeast Co Ltd   (Japan)

^e UNIVERSITY OF TOKYO   (Japan)

^f UNIVERSITY OF WISCONSIN MADISON   (United States)

^g SAITAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

Blood stream; Osteoblasts; Platelet endothelial cell adhesion molecule 1 positive cells

Indexed keywords

COLONY STIMULATING FACTOR 1; CYTOKINE; INTERLEUKIN 34; MESSENGER RNA; OSTEOCLAST DIFFERENTIATION FACTOR; UNCLASSIFIED DRUG; VITAMIN D; VITAMIN D RECEPTOR;

AGED; ALBERS SCHOENBERG DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE EROSION; HYPERCALCEMIA; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NEWBORN; NONHUMAN; OSTEOCLAST; OSTEOCLASTOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN; UPREGULATION;

ANIMALS; IMMUNOHISTOCHEMISTRY; INTERLEUKINS; MICE; MICE, TRANSGENIC; OSTEOCLASTS; OSTEOPETROSIS; SPLEEN; VITAMIN D;

EID: 84862519710     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1207361109     Document Type: Article

References (40)

1. Boyle WJ, Simonet WS, Lacey DL (2003) Osteoclast differentiation and activation. Nature 423:337-342.
2. Suda T, et al. (1999) Modulation of osteoclast differentiation and function by the new membersof the tumor necrosis factor receptor and ligand families. Endocr Rev 20:345-357.
3. Stanley ER, Berg KL, Einstein DB, Lee PS, Yeung YG (1994) The biology and action of colony stimulating factor-1. Stem Cells 12(Suppl 1):15-24, discussion 25.
4. Yoshida H, et al. (1990) The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene. Nature 345:442-444.
5. Wiktor-Jedrzejczak WW, Ahmed A, Szczylik C, Skelly RR (1982) Hematological characterization of congenital osteopetrosis in op/op mouse. Possible mechanism for abnormal macrophage differentiation. J Exp Med 156:1516-1527.
6. Kodama H, et al. (1991) Congenital osteoclast deficiency in osteopetrotic (op/op) mice is cured by injections of macrophage colony-stimulating factor. J Exp Med 173:269-272.
7. Begg SK, et al. (1993) Delayed hematopoietic development in osteopetrotic (op/op) mice. J Exp Med 177:237-242.
8. Dai XM, et al. (2002) Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects. Blood 99:111-120.
9. Cecchini MG, et al. (1994) Role of colony stimulating factor-1 in the establishment and regulation of tissue macrophages during postnatal development of the mouse. Development 120:1357-1372.
10. Yamamoto T, et al. (2008) Macrophage colony-stimulating factor is indispensable for repopulation and differentiation of Kupffer cells but not for splenic red pulp macrophages in osteopetrotic (op/op) mice after macrophage depletion. Cell Tissue Res 332:245-256.
11. Niida S, et al. (1999) Vascular endothelial growth factor can substitute for macrophage colony-stimulating factor in the support of osteoclastic bone resorption. J Exp Med 190:293-298.
12. Niida S, et al. (2005) VEGF receptor 1 signaling is essential for osteoclast development and bone marrow formation in colony-stimulating factor 1-deficient mice. Proc Natl Acad Sci USA 102:14016-14021.
13. Lean JM, Fuller K, Chambers TJ (2001) FLT3 ligand can substitute for macrophage colony-stimulating factor in support of osteoclast differentiation and function. Blood 98:2707-2713.
14. Lin H, et al. (2008) Discovery of a cytokine and its receptor by functional screening of the extracellular proteome. Science 320:807-811.
15. Wei S, et al. (2010) Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells. J Leukoc Biol 88:495-505.
16. Chen Z, Buki K, Vääräniemi J, Gu G, Väänä nen HK (2011) The critical role of IL-34 in osteoclastogenesis. PLoS ONE 6:e18689.
17. Baud'huin M, et al. (2010) Interleukin-34 is expressed by giant cell tumours of bone and plays a key role in RANKL-induced osteoclastogenesis. J Pathol 221:77-86.
18. Mizoguchi T, et al. (2009) Identification of cell cycle-arrested quiescent osteoclast precursors in vivo. J Cell Biol 184:541-554.
19. DeLuca HF (2004) Overview of general physiologic features and functions of vitamin D. Am J Clin Nutr 80(6 Suppl):1689S-1696S.
20. Shevde NK, et al. (2002) A potent analog of 1alpha,25-dihydroxyvitamin D3 selectively induces bone formation. Proc Natl Acad Sci USA 99:13487-13491.
21. Sato M, et al. (2007) New 19-nor-(20S)-1alpha,25-dihydroxyvitamin D3 analogs strongly stimulate osteoclast formation both in vivo and in vitro. Bone 40:293-304.
22. Wong MS, Delansorne R, Man RY, Vanhoutte PM (2008) Vitamin D derivatives acutely reduce endothelium-dependent contractions in the aorta of the spontaneously hypertensive rat. Am J Physiol Heart Circ Physiol 295:H289-H296.
23. Mantell DJ, Owens PE, Bundred NJ, Mawer EB, Canfield AE (2000) 1 α,25-dihydroxyvitamin D(3) inhibits angiogenesis in vitro and in vivo. Circ Res 87:214-220.
24. Hisa T, et al. (1996) Vitamin D inhibits endothelial cell migration. Arch Dermatol Res 288:262-263.
25. Broermann A, et al. (2011) Dissociation of VE-PTP from VE-cadherin is required for leukocyte extravasation and for VEGF-induced vascular permeability in vivo. J Exp Med 208:2393-2401.
26. Muto A, et al. (2011) Lineage-committed osteoclast precursors circulate in blood and settle down into bone. J Bone Miner Res 26:2978-2990.
27. Ishii M, et al. (2009) Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis. Nature 458:524-528.
28. Grunewald M, et al. (2006) VEGF-induced adult neovascularization: Recruitment, retention, and role of accessory cells. Cell 124:175-189.
29. Bergmann CE, et al. (2006) Arteriogenesis depends on circulating monocytes and macrophage accumulation and is severely depressed in op/op mice. J Leukoc Biol 80:59-65.
30. Lobov IB, et al. (2005) WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature. Nature 437:417-421.
31. Kubota Y, et al. (2009) M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis. J Exp Med 206:1089-1102.
32. Garceau V, et al. (2010) Pivotal Advance: Avian colony-stimulating factor 1 (CSF-1), interleukin-34 (IL-34), and CSF-1 receptor genes and gene products. J Leukoc Biol 87:753-764.
33. Chemel M, et al. (2012) Interleukin 34 expression is associated with synovitis severity in rheumatoid arthritis patients. Ann Rheum Dis 71:150-154.
34. Hwang SJ, et al. (2012) Interleukin-34 produced by human fibroblast-like synovial cells in rheumatoid arthritis supports osteoclastogenesis. Arthritis Res Ther 14:R14.
35. Tanaka S, et al. (1993) Macrophage colony-stimulating factor is indispensable for both proliferation and differentiation of osteoclast progenitors. J Clin Invest 91:257-263.
36. Miyamoto K, et al. (2011) Osteoclasts are dispensable for hematopoietic stem cell maintenance and mobilization. J Exp Med 208:2175-2181.
37. Swirski FK, et al. (2009) Identification of splenic reservoir monocytes and their deployment to inflammatory sites. Science 325:612-616.
38. Tagliani E, et al. (2011) Coordinate regulation of tissue macrophage and dendritic cell population dynamics by CSF-1. J Exp Med 208:1901-1916.
39. Kong YY, et al. (1999) OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 397:315-323.
40. Li M, et al. (2006) Topical vitamin D3 and low-calcemic analogs induce thymic stromal lymphopoietin in mouse keratinocytes and trigger an atopic dermatitis. Proc Natl Acad Sci USA 103:11736-11741.