Lipid core peptide targeting the cathepsin D hemoglobinase of Schistosoma mansoni as a component of a schistosomiasis vaccine

Human Vaccines and Immunotherapeutics

Volumn 10, Issue 2, 2014, Pages 399-409

  Dougall, Annette M ^a   Skwarczynski, Mariusz ^a,b   Khoshnejad, Makan ^b   Chandrudu, Saranya ^b   Daly, Norelle L ^a   Toth, Istvan ^a,b   Loukas, Alex ^a  

^a JAMES COOK UNIVERSITY   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Cathepsin D; Conformational epitope; Lipopeptide; Peptide antigen; Schistosomiasis; Self adjuvanting; Vaccine delivery

Indexed keywords

ANTISCHISTOSOMAL AGENT; ASPARTIC PROTEINASE; CATHEPSIN D HEMOGLOBINASE; CATHEPSIN D HEMOGLOBINASE LIPID CORE PEPTIDE 1; CATHEPSIN D HEMOGLOBINASE LIPID CORE PEPTIDE 2; EPITOPE; FREUND ADJUVANT; IMMUNOGLOBULIN G ANTIBODY; NEUTRALIZING ANTIBODY; SCHISTOSOMA VACCINE; UNCLASSIFIED DRUG; CATHEPSIN D; HELMINTH ANTIBODY; IMMUNOLOGICAL ADJUVANT; VACCINE;

ADULT; ALPHA HELIX; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; BIOENGINEERING; CARBOXY TERMINAL SEQUENCE; CELL STRAIN CACO 2; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG DELIVERY SYSTEM; DRUG SYNTHESIS; DRUG TARGETING; ENZYME ACTIVITY; IMMUNIZATION; IMMUNOHISTOCHEMISTRY; INFECTION CONTROL; MOLECULAR MODEL; MOUSE; NONHUMAN; PROTEIN CONFORMATION; SCHISTOSOMIASIS MANSONI; STRUCTURE ACTIVITY RELATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; BLOOD; CHEMICAL STRUCTURE; CHEMISTRY; DISEASE MODEL; ENZYMOLOGY; FEMALE; GENETICS; IMMUNOLOGY; MALE; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, HELMINTH; ANTIBODIES, NEUTRALIZING; CATHEPSIN D; DISEASE MODELS, ANIMAL; EPITOPES; FEMALE; MALE; MICE, INBRED BALB C; MODELS, MOLECULAR; PROTEIN CONFORMATION; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS; VACCINES;

EID: 84897017105     PISSN: 21645515     EISSN: 2164554X     Source Type: Journal    
DOI: 10.4161/hv.27057     Document Type: Article

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