Scalable synthesis of a nonracemic α-arylpropionic acid via ketene desymmetrization for a glucokinase activator

Organic Process Research and Development

Volumn 18, Issue 3, 2014, Pages 437-445

  Yamagami, Takafumi ^a   Moriyama, Noriaki ^a   Kyuhara, Masahiro ^a   Moroda, Atsushi ^a   Uemura, Takeshi ^a   Matsumae, Hiroaki ^a   Moritani, Yasunori ^a   Inoue, Isao ^a  

^a MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMISTRY;

ARYLPROPIONIC ACIDS; CHIRAL AUXILIARIES; CHIRAL CARBOXYLIC ACIDS; DESYM-METRIZATION; ENANTIOSELECTIVE HYDROGENATION; RESEARCH AND DEVELOPMENT; SCALABLE SYNTHESIS; SYNTHETIC APPROACH;

CARBOXYLIC ACIDS;

EID: 84897015462     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op400354g     Document Type: Article

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