Sulfur contamination due to quenching of halogenation reactions with sodium thiosulfate: Resolution of process problems via improved quench protocols

Organic Process Research and Development

Volumn 12, Issue 1, 2008, Pages 116-119

  Xiang, Yanqiao ^a   Caron, Pierre Yves ^a   Lillie, Brett M ^a   Vaidyanathan, Rajappa ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 38949187463     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op700227p     Document Type: Article

References (13)

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9. The product was isolated by concentrating the solution to dryness and not by crystallization. This was done in order to avoid any removal of sulfur by crystallization and to determine the true amount of sulfur in the sample.
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12. Unfortunately, experimental data on the solubility of elemental sulfur in these organic solvents was not readily available in the literature.
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