Caffeic acid reduces cutaneous tumor necrosis factor alpha (TNF-α), IL-6and IL-1 βlevels and ameliorates skin edema in acute and chronic model of cutaneous inflammation in mice

Biological and Pharmaceutical Bulletin

Volumn 37, Issue 3, 2014, Pages 347-354

  Zhang, Mengjun ^a   Zhou, Juan ^a   Wang, Li ^a   Li, Bin ^b   Guo, Jiawei ^a   Guan, Xiao ^a   Han, Qingjuan ^a   Zhang, Huijing ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b CHONGQING UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

12 O tetradecanoyl phorbol 13 acetate (TPA) induced ear edema model; 3,4 dihydroxycinnamic acid; Keratinocyte; Pro inflammatory cytokine

Indexed keywords

CAFFEIC ACID; DEXAMETHASONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; MYELOPEROXIDASE; PHORBOL 13 ACETATE 12 MYRISTATE; TUMOR NECROSIS FACTOR ALPHA;

ACUTE DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHRONIC DISEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DERMATITIS; DOSE RESPONSE; DRUG DOSE COMPARISON; ENZYME ACTIVITY; HISTOPATHOLOGY; IL 1BETA GENE; IL 6 GENE; IN VITRO STUDY; KERATINOCYTE; MOUSE; NEUTROPHIL; NONHUMAN; PROTEIN SYNTHESIS INHIBITION; RNA SYNTHESIS; SKIN EDEMA; TNF ALPHA GENE; TRANSCRIPTION INITIATION;

ADMINISTRATION, TOPICAL; ANIMALS; ANTI-INFLAMMATORY AGENTS; CAFFEIC ACIDS; DERMATITIS, CONTACT; DOSE-RESPONSE RELATIONSHIP, DRUG; EDEMA; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; INTERLEUKIN-6; KERATINOCYTES; MICE; MICE, INBRED BALB C; NEUTROPHILS; NF-KAPPA B; PEROXIDASE; PLANT EXTRACTS; RNA, MESSENGER; SKIN; TETRADECANOYLPHORBOL ACETATE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84897014608     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b13-00459     Document Type: Article

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