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Volumn 9, Issue 1, 2014, Pages

Promoter methylation of MLH1, PMS2, MSH2 and p16 is a phenomenon of advanced-stage HCCs

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; MISMATCH REPAIR PROTEIN PMS2; PROTEIN MLH1; PROTEIN MSH2;

EID: 84897005802     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0084453     Document Type: Article
Times cited : (31)

References (28)
  • 3
    • 0033661030 scopus 로고    scopus 로고
    • Molecular aspects of hepatocellular carcinoma
    • Moradpour D, Blum HE (2000) [Molecular aspects of hepatocellular carcinoma]. Zentralbl Chir 125: 592-596.
    • (2000) Zentralbl Chir , vol.125 , pp. 592-596
    • Moradpour, D.1    Blum, H.E.2
  • 4
    • 33745477343 scopus 로고    scopus 로고
    • Parallel epigenetic and genetic changes in the pathogenesis of hepatitis virus-associated hepatocellular carcinoma
    • DOI 10.1016/j.canlet.2005.07.009, PII S0304383505006683
    • Feitelson MA (2006) Parallel epigenetic and genetic changes in the pathogenesis of hepatitis virus-associated hepatocellular carcinoma. Cancer Lett 239: 10-20. (Pubitemid 43949592)
    • (2006) Cancer Letters , vol.239 , Issue.1 , pp. 10-20
    • Feitelson, M.A.1
  • 5
    • 0035377410 scopus 로고    scopus 로고
    • Genetic and epigenetic events in human hepatocarcinogenesis
    • Kondoh N, Wakatsuki T, Hada A, Shuda M, Tanaka K, et al. (2001) Genetic and epigenetic events in human hepatocarcinogenesis. Int J Oncol 18: 1271-1278.
    • (2001) Int J Oncol , vol.18 , pp. 1271-1278
    • Kondoh, N.1    Wakatsuki, T.2    Hada, A.3    Shuda, M.4    Tanaka, K.5
  • 6
    • 40949161396 scopus 로고    scopus 로고
    • Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma
    • DOI 10.1002/hep.22110
    • Nishida N, Nagasaka T, Nishimura T, Ikai I, Boland CR, et al. (2008) Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma. Hepatology 47: 908-918. (Pubitemid 351449682)
    • (2008) Hepatology , vol.47 , Issue.3 , pp. 908-918
    • Nishida, N.1    Nagasaka, T.2    Nishimura, T.3    Ikai, I.4    Boland, C.R.5    Goel, A.6
  • 7
    • 77950628676 scopus 로고    scopus 로고
    • DNA methylation changes in normal liver tissues and hepatocellular carcinoma with different viral infection
    • Feng Q, Stern JE, Hawes SE, Lu H, Jiang M, et al. (2010) DNA methylation changes in normal liver tissues and hepatocellular carcinoma with different viral infection. Exp Mol Pathol 88: 287-292.
    • (2010) Exp Mol Pathol , vol.88 , pp. 287-292
    • Feng, Q.1    Stern, J.E.2    Hawes, S.E.3    Lu, H.4    Jiang, M.5
  • 9
    • 36248987090 scopus 로고    scopus 로고
    • Mismatch Repair and Multi-Drug Resistance Genes Expression in Relation to HCV-Associated Hepatocellular Carcinoma
    • Abdel-Rahman N, Zekri AAB, Abdalah S, Saleh M, El-Sherif GM, et al. (2001) Mismatch Repair and Multi-Drug Resistance Genes Expression in Relation to HCV-Associated Hepatocellular Carcinoma. Journal of Egyptian Nat Cancer Inst 13: 129-138.
    • (2001) Journal of Egyptian Nat Cancer Inst , vol.13 , pp. 129-138
    • Abdel-Rahman, N.1    Zekri, A.A.B.2    Abdalah, S.3    Saleh, M.4    El-Sherif, G.M.5
  • 10
    • 84862799636 scopus 로고    scopus 로고
    • Hepatitis C virus Core protein overcomes stress-induced premature senescence by down-regulating p16 expression via DNA methylation
    • Lim JS, Park SH, Jang KL (2012) Hepatitis C virus Core protein overcomes stress-induced premature senescence by down-regulating p16 expression via DNA methylation. Cancer Lett 321: 154-161.
    • (2012) Cancer Lett , vol.321 , pp. 154-161
    • Lim, J.S.1    Park, S.H.2    Jang, K.L.3
  • 11
    • 84868201629 scopus 로고    scopus 로고
    • Methylome analysis and integrative profiling of human HCCs identify novel protumorigenic factors
    • Neumann O, Kesselmeier M, Geffers R, Pellegrino R, Radlwimmer B, et al. (2012) Methylome analysis and integrative profiling of human HCCs identify novel protumorigenic factors. Hepatology 56: 1817-1827.
    • (2012) Hepatology , vol.56 , pp. 1817-1827
    • Neumann, O.1    Kesselmeier, M.2    Geffers, R.3    Pellegrino, R.4    Radlwimmer, B.5
  • 12
    • 77954168986 scopus 로고    scopus 로고
    • Identification of genes preferentially methylated in hepatitis C virus-related hepatocellular carcinoma
    • Deng YB, Nagae G, Midorikawa Y, Yagi K, Tsutsumi S, et al. (2010) Identification of genes preferentially methylated in hepatitis C virus-related hepatocellular carcinoma. Cancer Sci 101: 1501-1510.
    • (2010) Cancer Sci , vol.101 , pp. 1501-1510
    • Deng, Y.B.1    Nagae, G.2    Midorikawa, Y.3    Yagi, K.4    Tsutsumi, S.5
  • 13
    • 84862499187 scopus 로고    scopus 로고
    • Promoter hypermethylation of DNA damage response genes in hepatocellular carcinoma
    • Li Z, Zhang H, Yang J, Hao T, Li S (2012) Promoter hypermethylation of DNA damage response genes in hepatocellular carcinoma. Cell Biol Int 36: 427-432.
    • (2012) Cell Biol Int , vol.36 , pp. 427-432
    • Li, Z.1    Zhang, H.2    Yang, J.3    Hao, T.4    Li, S.5
  • 15
    • 77956978819 scopus 로고    scopus 로고
    • Detection of aberrant p16INK4A methylation in sera of patients with HCV-related liver diseases: An Egyptian study
    • Ahmed R, Salama H, Fouad A, Sabry D, AbdAlah el S, et al. (2010) Detection of aberrant p16INK4A methylation in sera of patients with HCV-related liver diseases: An Egyptian study. Med Sci Monit 16: CR410-415.
    • (2010) Med Sci Monit , vol.16
    • Ahmed, R.1    Salama, H.2    Fouad, A.3    Sabry, D.4    AbdAlah El, S.5
  • 18
    • 0028785603 scopus 로고
    • Microsatellite instability and mutations of the transforming growth factor beta type II receptor gene in colorectal cancer
    • Parsons R, Myeroff LL, Liu B, Willson JK, Markowitz SD, et al. (1995) Microsatellite instability and mutations of the transforming growth factor beta type II receptor gene in colorectal cancer. Cancer Res 55: 5548-5550.
    • (1995) Cancer Res , vol.55 , pp. 5548-5550
    • Parsons, R.1    Myeroff, L.L.2    Liu, B.3    Willson, J.K.4    Markowitz, S.D.5
  • 21
    • 33644967934 scopus 로고    scopus 로고
    • Methylation of mismatch repair gene (MMR) in primary hepatocellular carcinoma
    • Zhang CJ, Li HM, Yau LM, Suen KW, Zhou GY, et al. (2004) [Methylation of mismatch repair gene (MMR) in primary hepatocellular carcinoma]. Zhonghua Bing Li Xue Za Zhi 33: 433-436.
    • (2004) Zhonghua Bing Li Xue Za Zhi , vol.33 , pp. 433-436
    • Zhang, C.J.1    Li, H.M.2    Yau, L.M.3    Suen, K.W.4    Zhou, G.Y.5
  • 22
    • 78649499912 scopus 로고    scopus 로고
    • Immunohistochemical expression of mismatch repair genes (hMSH2 and hMLH1) in hepatocellular carcinoma in Egypt
    • Helal TE, Khamis NS, El-Sharkawy TM, Nada OH, Radwan NA (2010) Immunohistochemical expression of mismatch repair genes (hMSH2 and hMLH1) in hepatocellular carcinoma in Egypt. APMIS 118: 934-940.
    • (2010) APMIS , vol.118 , pp. 934-940
    • Helal, T.E.1    Khamis, N.S.2    El-Sharkawy, T.M.3    Nada, O.H.4    Radwan, N.A.5
  • 23
    • 0035319593 scopus 로고    scopus 로고
    • Reduced expression of hMLH1 and hMSH2 gene products in high-grade hepatocellular carcinoma
    • Wani Y, Notohara K, Tsukayama C, Okada S (2001) Reduced expression of hMLH1 and hMSH2 gene products in high-grade hepatocellular carcinoma. Acta Med Okayama 55: 65-71. (Pubitemid 33605240)
    • (2001) Acta Medica Okayama , vol.55 , Issue.2 , pp. 65-71
    • Wani, Y.1    Notohara, K.2    Tsukayama, C.3    Okada, S.4
  • 25
    • 39249084744 scopus 로고    scopus 로고
    • Hepatitis C virus core protein downregulates E-cadherin expression via activation of DNA methyltransferase 1 and 3b
    • Arora P, Kim EO, Jung JK, Jang KL (2008) Hepatitis C virus core protein downregulates E-cadherin expression via activation of DNA methyltransferase 1 and 3b. Cancer Lett 261: 244-252.
    • (2008) Cancer Lett , vol.261 , pp. 244-252
    • Arora, P.1    Kim, E.O.2    Jung, J.K.3    Jang, K.L.4
  • 26
    • 84864284903 scopus 로고    scopus 로고
    • DNA methyltransferases 1 and 3b expression in Huh-7 cells expressing HCV core protein of different genotypes
    • Benegiamo G, Vinciguerra M, Mazzoccoli G, Piepoli A, Andriulli A, et al. (2012) DNA methyltransferases 1 and 3b expression in Huh-7 cells expressing HCV core protein of different genotypes. Dig Dis Sci 57: 1598-1603.
    • (2012) Dig Dis Sci , vol.57 , pp. 1598-1603
    • Benegiamo, G.1    Vinciguerra, M.2    Mazzoccoli, G.3    Piepoli, A.4    Andriulli, A.5
  • 27
    • 32244444440 scopus 로고    scopus 로고
    • Regulation of hMSH2 and hMLH1 expression in the human colon cancer cell line SW1116 by DNA methyltransferase 1
    • DOI 10.1016/j.canlet.2005.03.005, PII S0304383505002302
    • Fang JY, Lu R, Mikovits JA, Cheng ZH, Zhu HY, et al. (2006) Regulation of hMSH2 and hMLH1 expression in the human colon cancer cell line SW1116 by DNA methyltransferase 1. Cancer Lett 233: 124-130. (Pubitemid 43214570)
    • (2006) Cancer Letters , vol.233 , Issue.1 , pp. 124-130
    • Fang, J.Y.1    Lu, R.2    Mikovits, J.A.3    Cheng, Z.H.4    Zhu, H.Y.5    Chen, Y.X.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.