The unique manuka effect: Why New Zealand manuka honey fails the AOAC 998.12 C-4 sugar method

Journal of Agricultural and Food Chemistry

Volumn 62, Issue 12, 2014, Pages 2615-2622

  Rogers, Karyne M ^a   Grainger, Megan ^b   Manley Harris, Merilyn ^b  

^a GNS SCIENCE   (New Zealand)

^b UNIVERSITY OF WAIKATO   (New Zealand)

Author keywords

5 hydroxymethylfurfural; adulteration; AOAC 998.12; apparent C 4 sugars; carbon isotope; dihydroxyacetone; honey; Leptospermum scoparium; manuka; methylglyoxal; New Zealand

Indexed keywords

ISOTOPES; PROTEINS; SUGARS;

5 HYDROXYMETHYL FURFURALS; ADULTERATION; AOAC 998.12; CARBON ISOTOPES; DIHYDROXYACETONE; HONEY; LEPTOSPERMUM SCOPARIUM; MANUKA; METHYLGLYOXAL; NEW ZEALAND;

FOOD PRODUCTS;

CARBOHYDRATE; CARBON; METHYLGLYOXAL;

ARTICLE; CLASSIFICATION; FOOD ANALYSIS; FOOD CONTAMINATION; FOOD STORAGE; HONEY; METHODOLOGY; NEW ZEALAND; STANDARD;

CARBOHYDRATES; CARBON ISOTOPES; FOOD ANALYSIS; FOOD CONTAMINATION; FOOD STORAGE; HONEY; NEW ZEALAND; PYRUVALDEHYDE;

LEPTOSPERMUM SCOPARIUM; TRIFOLIUM;

EID: 84896964966     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf404767b     Document Type: Article

References (24)

1. Allen, K. L.; Molan, P. C.; Reid, G. M. A survey of the antibacterial activity of some New Zealand honeys J. Pharm. Pharmacol. 1991, 43, 817-822
2. Adams, C. J.; Boult, C. H.; Deadman, B. J.; Farr, J. M.; Grainger, M. N. C.; Manley-Harris, M.; Snow, M. J. Isolation by HPLC and characterization of the bioactive fraction of New Zealand manuka (Leptospermum scoparium) honey Carbohydr. Res. 2008, 343, 651-659
3. Mavric, E.; Wittmann, S.; Barth, G.; Henle, T. Identification and quantification of methylglyoxal as the dominant antibacterial constituent of manuka (Leptospermum scoparium) honeys from New Zealand Mol. Nutr. Food Res. 2008, 52, 483-489
4. Adams, C. J.; Manley-Harris, M.; Molan, P. C. The origin of methylglyoxal in New Zealand manuka (Leptospermum scoparium) honey Carbohydr. Res. 2009, 344, 1050-1053
5. Fallico, B.; Zappalà, M.; Arena, E.; Verzera, A. Effects of conditioning on HMF content in unifloral honeys Food Chem. 2005, 85, 305-313
6. AOAC Official Method 998.12. C-4 plant sugars in honey. In Official Methods of Analysis of AOAC International, 16 th ed.; Cunniff, P., Ed.; AOAC International: Gaithersburg, MD, USA, 1999; Vol. 2, pp 27-30.
7. Rogers, K. M.; Stewart, S.; Pyne, R.; Douance, C.; Cooper, J.; Phillips, A.; Sim, M.; Rogers, P. Investigating AOAC 998.12 C-4 sugar fails in New Zealand honey J. Agric. Food Chem. 2014, 10.1021/jf40766f
8. Rogers, K. M.; Cook, J.; Krueger, D.; Beckmann, K. Report of an inter laboratory comparison exercise: modification of AOAC Official Method 998.12 to add filtration and/or centrifugation J. AOAC Int. 2013, 96, 607-614
9. 12C isotopic ratio Food Chem. 2003, 82, 633-636
10. Padovan, G. J.; Rodrigues, L. P.; Leme, I. A.; De Jong, D.; Marchini, J. S. Presence of C4 sugars in honey samples detected by the carbon isotope ratio measured by IRMS Eurasian J. Anal. Chem. 2007, 2, 134-141
11. 12C ratio: collaborative study J. Assoc. Off. Anal. Chem. 1978, 61, 746-750
12. 4 sugar tests on New Zealand manuka honey Rapid Commun. Mass Spectrom. 2010, 24, 2370-2374
13. White, J. W.; Winters, K. Honey protein as internal standard for stable carbon isotope ratio detection of adulteration honey J. Assoc. Off. Anal. Chem. 1989, 72, 907-911
14. Atrott, J.; Haberlau, S.; Henle, T. Studies on the formation of methylglyoxal from dihydroxyacetone in manuka (Leptospermum scoparium) honey Carbohydr. Res. 2012, 361, 7-11
15. Windsor, S.; Pappalardo, M.; Brooks, P.; Williams, S.; Manley-Harris, M. A Convenient new analysis of dihydroxyacetone and methylglyoxal applied to Australian Leptospermum honeys J. Pharmacogn. Phytother. 2012, 4, 6-11
16. Kawashima, K.; Itoh, H.; Chibata, I. Non-enzymatic browning reactions of dihydroxyacetone with amino acids or their esters Agric. Biol. Chem. 1998, 44, 1595-1599
17. De Genhardt, T. P.; Thorpe, S. R.; Baynes, J. W. Chemical modification of proteins by methylglyoxal Cell. Mol. Biol. 1991, 44, 1139-1145
18. Erbersdobler, H. Loss of lysine during manufacture and storage of milk powder Milchwissenschaft 1970, 25, 280-284
19. El, S. N.; Kavas, A. Available lysine in dried milk after processing Int. J. Food Sci. Nutr. 1997, 48, 109-111
20. Thomas, M. E. C.; Scher, J.; Desobry-Banon, S.; Desobry, S. Milk powders ageing: effect on physical and functional properties Crit. Rev. Food Sci. Nutr. 2004, 44, 297-322
21. 13C amino acids in plant proteins Rapid Commun. Mass Spectrom. 2011, 25, 2981-2988
22. Larsen, T.; Taylor, D. L.; Leigh, M. B.; O'Brien, D. M. Stable isotope fingerprinting: a novel method for identifying plant, fungal or bacterial origins of amino acids Ecology 2009, 90, 3526-3535
23. O'Brien, D. M.; Boggs, C. L.; Fogel, M. L. Pollen feeding in the butterfly Heliconius charitonia: isotopic evidence for essential amino acid transfer from pollen to eggs Proc. R. Soc. B 2003, 270, 2631-2636
24. Majtan, J.; Klaudiny, J.; Bohova, J.; Kohutova, L.; Dzurova, M.; Sediva, M.; Bartosova, M.; Majtan, V. Methylglyoxal-induced modifications of significant honeybee proteinous components in manuka honey: possible therapeutic implications Fitoterapia 2012, 83, 671-677