메뉴 건너뛰기




Volumn 7, Issue 1, 2014, Pages 45-52

Adult human mesenchymal stromal cells and the treatment of graft versus host disease

Author keywords

Acute; Chronic; Graft versus host disease; Mesenchymal stromal cells

Indexed keywords

CORTICOSTEROID; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2; IMMUNOSUPPRESSIVE AGENT;

EID: 84896896801     PISSN: None     EISSN: 11786957     Source Type: Journal    
DOI: 10.2147/SCCAA.S37506     Document Type: Review
Times cited : (30)

References (72)
  • 1
    • 56849132135 scopus 로고    scopus 로고
    • Transfusion-associated graft-versus-host disease
    • Ruhl H, Bein G, Sachs UJ. Transfusion-associated graft-versus-host disease. Transfus Med Rev. 2009;23:62-71.
    • (2009) Transfus Med Rev , vol.23 , pp. 62-71
    • Ruhl, H.1    Bein, G.2    Sachs, U.J.3
  • 2
    • 0004647768 scopus 로고
    • The effect of adult chick organ graft on the chick embryo
    • Murphy J. The effect of adult chick organ graft on the chick embryo. J Exp Med. 1916;24:1-6.
    • (1916) J Exp Med , vol.24 , pp. 1-6
    • Murphy, J.1
  • 3
    • 33644911678 scopus 로고
    • The impact on the developing embryo and newborn animal of adult homologous cells
    • Simonsen M. The impact on the developing embryo and newborn animal of adult homologous cells. Acta Pathol Microbiol Scand. 1957;40: 480-500.
    • (1957) Acta Pathol Microbiol Scand , vol.40 , pp. 480-500
    • Simonsen, M.1
  • 4
    • 0001426462 scopus 로고
    • Quantitative studies on tissue transplantation immunity. IV. Induction of tolerance in newborn mice and studies on the phenomenon of runt disease
    • Billingham RE, Brent L. Quantitative studies on tissue transplantation immunity. IV. Induction of tolerance in newborn mice and studies on the phenomenon of runt disease. Phil Trans R Soc B Biol Sci. 1959;242:439.
    • (1959) Phil Trans R Soc B Biol Sci , vol.242 , pp. 439
    • Billingham, R.E.1    Brent, L.2
  • 5
    • 0000970496 scopus 로고
    • Intravenous infusion of bone marrow in patients receiving radiation and chemotherapy
    • Thomas ED, Lochte HL Jr, Lu WC, Ferrebee JW. Intravenous infusion of bone marrow in patients receiving radiation and chemotherapy. N Engl J Med. 1957;257:491-496.
    • (1957) N Engl J Med , vol.257 , pp. 491-496
    • Thomas, E.D.1    Lochte Jr., H.L.2    Lu, W.C.3    Ferrebee, J.W.4
  • 6
    • 0014806577 scopus 로고
    • A compendium of reported human bone marrow transplants
    • Bortin MM. A compendium of reported human bone marrow transplants. Transplantation. 1970;9:571-587.
    • (1970) Transplantation , vol.9 , pp. 571-587
    • Bortin, M.M.1
  • 7
    • 38349035672 scopus 로고    scopus 로고
    • Eleven million donors in bone marrow donors worldwide! Time for reassessment?
    • van Rood JJ, Oudshoorn M. Eleven million donors in bone marrow donors worldwide! Time for reassessment? Bone Marrow Transplant. 2008;41:1-9.
    • (2008) Bone Marrow Transplant , vol.41 , pp. 1-9
    • van Rood, J.J.1    Oudshoorn, M.2
  • 8
    • 0013989358 scopus 로고
    • The biology of graft-versus-host reactions
    • Billingham RE. The biology of graft-versus-host reactions. Harvey Lect. 1966;62:21-78.
    • (1966) Harvey Lect , vol.62 , pp. 21-78
    • Billingham, R.E.1
  • 9
    • 29844440286 scopus 로고    scopus 로고
    • A revision of Billingham's tenets: The central role of lymphocyte migration in acute graft-versus-host disease
    • Sackstein R. A revision of Billingham's tenets: the central role of lymphocyte migration in acute graft-versus-host disease. Biol Blood Marrow Transplant. 2006;12(1 Suppl 1):2-8.
    • (2006) Biol Blood Marrow Transplant , vol.12 , Issue.1 SUPPL. 1 , pp. 2-8
    • Sackstein, R.1
  • 10
    • 30344487601 scopus 로고    scopus 로고
    • The clinical spectrum of acute graft-versus-host disease
    • Deeg HJ, Antin JH. The clinical spectrum of acute graft-versus-host disease. Semin Hematol. 2006;43:24-31.
    • (2006) Semin Hematol , vol.43 , pp. 24-31
    • Deeg, H.J.1    Antin, J.H.2
  • 12
    • 84873044177 scopus 로고    scopus 로고
    • Discovery and validation of graft-versus-host disease biomarkers
    • Paczesny S. Discovery and validation of graft-versus-host disease biomarkers. Blood. 2013;121:585-594.
    • (2013) Blood , vol.121 , pp. 585-594
    • Paczesny, S.1
  • 13
    • 0036048349 scopus 로고    scopus 로고
    • Response of 443 patients to steroids as primary therapy for acute graft-versus-host disease: Comparison of grading systems
    • MacMillan ML, Weisdorf DJ, Wagner JE, et al. Response of 443 patients to steroids as primary therapy for acute graft-versus-host disease: comparison of grading systems. Biol Blood Marrow Transplant. 2002;8: 387-394.
    • (2002) Biol Blood Marrow Transplant , vol.8 , pp. 387-394
    • Macmillan, M.L.1    Weisdorf, D.J.2    Wagner, J.E.3
  • 14
    • 34248356010 scopus 로고    scopus 로고
    • How I treat refractory acute GVHD
    • Deeg HJ. How I treat refractory acute GVHD. Blood. 2007;109: 4119-4126.
    • (2007) Blood , vol.109 , pp. 4119-4126
    • Deeg, H.J.1
  • 16
    • 84862137300 scopus 로고    scopus 로고
    • First- and second-line systemic treatment of acute graft-versus-host disease: Recommendations of the American Society of Blood and Marrow Transplantation
    • Martin PJ, Rizzo JD, Wingard JR, et al. First- and second-line systemic treatment of acute graft-versus-host disease: recommendations of the American Society of Blood and Marrow Transplantation. Biol Blood Marrow Transplant. 2012;18:1150-1163.
    • (2012) Biol Blood Marrow Transplant , vol.18 , pp. 1150-1163
    • Martin, P.J.1    Rizzo, J.D.2    Wingard, J.R.3
  • 17
    • 0018764352 scopus 로고
    • Antileukemic effect of graft-versus-host disease in human recipients of allogeneic-marrow grafts
    • Weiden PL, Flournoy N, Thomas ED, et al. Antileukemic effect of graft-versus-host disease in human recipients of allogeneic-marrow grafts. N Engl J Med. 1979;300:1068-1073.
    • (1979) N Engl J Med , vol.300 , pp. 1068-1073
    • Weiden, P.L.1    Flournoy, N.2    Thomas, E.D.3
  • 18
    • 3543051151 scopus 로고    scopus 로고
    • The Mortimer M. Bortin Lecture: To destroy by the reaction of immunity: The search for separation of graft-versus-leukemia and graft-versus-host
    • Truitt RL. The Mortimer M. Bortin Lecture: to destroy by the reaction of immunity: the search for separation of graft-versus-leukemia and graft-versus-host. Biol Blood Marrow Transplant. 2004;10:505-523.
    • (2004) Biol Blood Marrow Transplant , vol.10 , pp. 505-523
    • Truitt, R.L.1
  • 19
    • 44049086872 scopus 로고    scopus 로고
    • GVHD pathophysiology: Is acute different from chronic?
    • Toubai T, Sun Y, Reddy P. GVHD pathophysiology: is acute different from chronic? Best Pract Res Clin Haematol. 2008;21:101-117.
    • (2008) Best Pract Res Clin Haematol , vol.21 , pp. 101-117
    • Toubai, T.1    Sun, Y.2    Reddy, P.3
  • 20
    • 33846910425 scopus 로고    scopus 로고
    • Donor-derived thymic-dependent T cells cause chronic graft-versus-host disease
    • Sakoda Y, Hashimoto D, Asakura S, et al. Donor-derived thymic-dependent T cells cause chronic graft-versus-host disease. Blood. 2007;109:1756-1764.
    • (2007) Blood , vol.109 , pp. 1756-1764
    • Sakoda, Y.1    Hashimoto, D.2    Asakura, S.3
  • 21
    • 28744444180 scopus 로고    scopus 로고
    • National Institutes of Health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: I. Diagnosis and staging working group report
    • Filipovich AH, Weisdorf D, Pavletic S, et al. National Institutes of Health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: I. Diagnosis and staging working group report. Biol Blood Marrow Transplant. 2005;11:945-956.
    • (2005) Biol Blood Marrow Transplant , vol.11 , pp. 945-956
    • Filipovich, A.H.1    Weisdorf, D.2    Pavletic, S.3
  • 22
    • 77953057590 scopus 로고    scopus 로고
    • Current challenges in chronic graft-versus-host disease
    • Socie G, Ritz J, Martin PJ. Current challenges in chronic graft-versus-host disease. Biol Blood Marrow Transplant. 2010; 16(Suppl 1):S146-S151.
    • (2010) Biol Blood Marrow Transplant , vol.16 , Issue.SUPPL. 1
    • Socie, G.1    Ritz, J.2    Martin, P.J.3
  • 23
    • 84867167966 scopus 로고    scopus 로고
    • Oral chronic graft-vs-host disease characterization using the NIH scale
    • Fassil H, Bassim CW, Mays J, et al. Oral chronic graft-vs-host disease characterization using the NIH scale. J Dent Res. 2012; 91(Suppl 7):45S-51S.
    • (2012) J Dent Res , vol.91 , Issue.SUPPL. 7
    • Fassil, H.1    Bassim, C.W.2    Mays, J.3
  • 24
    • 44049106681 scopus 로고    scopus 로고
    • Diagnosis and manifestations of chronic graft-versus-host disease
    • Filipovich AH. Diagnosis and manifestations of chronic graft-versus-host disease. Best Pract Res Clin Haematol. 2008;21:251-257.
    • (2008) Best Pract Res Clin Haematol , vol.21 , pp. 251-257
    • Filipovich, A.H.1
  • 25
    • 33747713246 scopus 로고    scopus 로고
    • Minimal criteria for defning multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement
    • Dominici M, Le Blanc K, Mueller I, et al. Minimal criteria for defning multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy. 2006;8:315-317.
    • (2006) Cytotherapy , vol.8 , pp. 315-317
    • Dominici, M.1    Le Blanc, K.2    Mueller, I.3
  • 26
    • 0141484485 scopus 로고    scopus 로고
    • HLA expression and immunologic properties of differentiated and undif-ferentiated mesenchymal stem cells
    • Le Blanc K, Tammik C, Rosendahl K, Zetterberg E, Ringden O. HLA expression and immunologic properties of differentiated and undif-ferentiated mesenchymal stem cells. Exp Hematol. 2003;31:890-896.
    • (2003) Exp Hematol , vol.31 , pp. 890-896
    • Le Blanc, K.1    Tammik, C.2    Rosendahl, K.3    Zetterberg, E.4    Ringden, O.5
  • 27
    • 33847386693 scopus 로고    scopus 로고
    • Bone marrow mesenchy-mal stromal cells (BM-MSCs) from healthy donors and auto-immune disease patients reduce the proliferation of autologous- and allogeneic-stimulated lymphocytes in vitro
    • Bocelli-Tyndall C, Bracci L, Spagnoli G, et al. Bone marrow mesenchy-mal stromal cells (BM-MSCs) from healthy donors and auto-immune disease patients reduce the proliferation of autologous- and allogeneic-stimulated lymphocytes in vitro. Rheumatology (Oxford). 2007;46: 403-408.
    • (2007) Rheumatology (Oxford) , vol.46 , pp. 403-408
    • Bocelli-Tyndall, C.1    Bracci, L.2    Spagnoli, G.3
  • 28
    • 30144440925 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate B-cell functions
    • Corcione A, Benvenuto F, Ferretti E, et al. Human mesenchymal stem cells modulate B-cell functions. Blood. 2006;107:367-372.
    • (2006) Blood , vol.107 , pp. 367-372
    • Corcione, A.1    Benvenuto, F.2    Ferretti, E.3
  • 29
    • 33746514768 scopus 로고    scopus 로고
    • Donor-derived mesenchymal stem cells are immuno-genic in an allogeneic host and stimulate donor graft rejection in a nonmyeloablative setting
    • Nauta AJ, Westerhuis G, Kruisselbrink AB, Lurvink EG, Willemze R, Fibbe WE. Donor-derived mesenchymal stem cells are immuno-genic in an allogeneic host and stimulate donor graft rejection in a nonmyeloablative setting. Blood. 2006;108:2114-2120.
    • (2006) Blood , vol.108 , pp. 2114-2120
    • Nauta, A.J.1    Westerhuis, G.2    Kruisselbrink, A.B.3    Lurvink, E.G.4    Willemze, R.5    Fibbe, W.E.6
  • 30
    • 84872159367 scopus 로고    scopus 로고
    • Cellular and molecular interactions of mes-enchymal stem cells in innate immunity
    • Spaggiari GM, Moretta L. Cellular and molecular interactions of mes-enchymal stem cells in innate immunity. Immunol Cell Biol. 2013;91: 27-31.
    • (2013) Immunol Cell Biol , vol.91 , pp. 27-31
    • Spaggiari, G.M.1    Moretta, L.2
  • 31
    • 84875432362 scopus 로고    scopus 로고
    • Comparison of human mesenchymal stem cells derived from adipose and cord tissue
    • Choudhery MS, Badowski M, Muise A, Harris DT. Comparison of human mesenchymal stem cells derived from adipose and cord tissue. Cytotherapy. 2013;15:330-343.
    • (2013) Cytotherapy , vol.15 , pp. 330-343
    • Choudhery, M.S.1    Badowski, M.2    Muise, A.3    Harris, D.T.4
  • 32
    • 50249158511 scopus 로고    scopus 로고
    • Mesenchymal stem cells in health and disease
    • Uccelli A, Moretta L, Pistoia V. Mesenchymal stem cells in health and disease. Nat Rev Immunol. 2008;8:726-736.
    • (2008) Nat Rev Immunol , vol.8 , pp. 726-736
    • Uccelli, A.1    Moretta, L.2    Pistoia, V.3
  • 33
    • 78649733250 scopus 로고    scopus 로고
    • Bone marrow and umbilical cord blood human mesenchymal stem cells: State of the art
    • Malgieri A, Kantzari E, Patrizi MP, Gambardella S. Bone marrow and umbilical cord blood human mesenchymal stem cells: state of the art. Int J Clin Exp Med. 2010;3:248-269.
    • (2010) Int J Clin Exp Med , vol.3 , pp. 248-269
    • Malgieri, A.1    Kantzari, E.2    Patrizi, M.P.3    Gambardella, S.4
  • 34
    • 28244440913 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells
    • Kemp KC, Hows J, Donaldson C. Bone marrow-derived mesenchymal stem cells. Leuk Lymphoma. 2005;46:1531-1544.
    • (2005) Leuk Lymphoma , vol.46 , pp. 1531-1544
    • Kemp, K.C.1    Hows, J.2    Donaldson, C.3
  • 35
    • 36348946918 scopus 로고    scopus 로고
    • No alloantibodies against mesenchymal stromal cells, but presence of anti-fetal calf serum antibodies, after transplantation in allogeneic hematopoietic stem cell recipients
    • Sundin M, Ringden O, Sundberg B, Nava S, Gotherstrom C, Le Blanc K. No alloantibodies against mesenchymal stromal cells, but presence of anti-fetal calf serum antibodies, after transplantation in allogeneic hematopoietic stem cell recipients. Haematologica. 2007;92:1208-1215.
    • (2007) Haematologica , vol.92 , pp. 1208-1215
    • Sundin, M.1    Ringden, O.2    Sundberg, B.3    Nava, S.4    Gotherstrom, C.5    Le Blanc, K.6
  • 36
    • 2442713904 scopus 로고    scopus 로고
    • Internalized antigens must be removed to prepare hypoimmunogenic mesenchymal stem cells for cell and gene therapy
    • Spees JL, Gregory CA, Singh H, et al. Internalized antigens must be removed to prepare hypoimmunogenic mesenchymal stem cells for cell and gene therapy. Mol Ther. 2004;9:747-756.
    • (2004) Mol Ther , vol.9 , pp. 747-756
    • Spees, J.L.1    Gregory, C.A.2    Singh, H.3
  • 37
    • 33847652908 scopus 로고    scopus 로고
    • Optimization of in vitro expansion of human multipotent mesenchymal stromal cells for cell-therapy approaches: Further insights in the search for a fetal calf serum substitute
    • Bernardo ME, Avanzini MA, Perotti C, et al. Optimization of in vitro expansion of human multipotent mesenchymal stromal cells for cell-therapy approaches: further insights in the search for a fetal calf serum substitute. J Cell Physiol. 2007;211:121-130.
    • (2007) J Cell Physiol , vol.211 , pp. 121-130
    • Bernardo, M.E.1    Avanzini, M.A.2    Perotti, C.3
  • 38
    • 84859745736 scopus 로고    scopus 로고
    • Platelet lysate from whole blood-derived pooled platelet concentrates and apheresis-derived platelet concentrates for the isolation and expansion of human bone marrow mesenchymal stromal cells: Production process, content and identifca-tion of active components
    • Fekete N, Gadelorge M, Furst D, et al. Platelet lysate from whole blood-derived pooled platelet concentrates and apheresis-derived platelet concentrates for the isolation and expansion of human bone marrow mesenchymal stromal cells: production process, content and identifca-tion of active components. Cytotherapy. 2012;14:540-554.
    • (2012) Cytotherapy , vol.14 , pp. 540-554
    • Fekete, N.1    Gadelorge, M.2    Furst, D.3
  • 39
    • 84858163803 scopus 로고    scopus 로고
    • Optimising human mesenchymal stem cell numbers for clinical application: A literature review
    • Fossett E, Khan WS. Optimising human mesenchymal stem cell numbers for clinical application: a literature review. Stem Cells Int. 2012;2012:465259.
    • (2012) Stem Cells Int , vol.2012 , pp. 465259
    • Fossett, E.1    Khan, W.S.2
  • 40
    • 81355134650 scopus 로고    scopus 로고
    • Toward a clinical-grade expansion of mesenchymal stem cells from human sources: A microcarrier-based culture system under xeno-free conditions
    • Santos F, Andrade PZ, Abecasis MM, et al. Toward a clinical-grade expansion of mesenchymal stem cells from human sources: a microcarrier-based culture system under xeno-free conditions. Tissue Eng Part C Methods. 2011;17:1201-1210.
    • (2011) Tissue Eng Part C Methods , vol.17 , pp. 1201-1210
    • Santos, F.1    Andrade, P.Z.2    Abecasis, M.M.3
  • 41
    • 84855745736 scopus 로고    scopus 로고
    • Tear physiology in dry eye associated with chronic GVHD
    • Khanal S, Tomlinson A. Tear physiology in dry eye associated with chronic GVHD. Bone Marrow Transplant. 2012;47:115-119.
    • (2012) Bone Marrow Transplant , vol.47 , pp. 115-119
    • Khanal, S.1    Tomlinson, A.2
  • 42
    • 84881092225 scopus 로고    scopus 로고
    • Immunological characterization of multipotent mesenchymal stromal cells - The International Society for Cellular Therapy (ISCT) working proposal
    • Krampera M, Galipeau J, Shi Y, Tarte K, Sensebe L. Immunological characterization of multipotent mesenchymal stromal cells - The International Society for Cellular Therapy (ISCT) working proposal. Cytotherapy. 2013;15:1054-1061.
    • (2013) Cytotherapy , vol.15 , pp. 1054-1061
    • Krampera, M.1    Galipeau, J.2    Shi, Y.3    Tarte, K.4    Sensebe, L.5
  • 43
    • 77954220716 scopus 로고    scopus 로고
    • Defning the probability that a cell therapy will produce a malignancy
    • Prockop DJ. Defning the probability that a cell therapy will produce a malignancy. Mol Ther. 2010;18:1249-1250.
    • (2010) Mol Ther , vol.18 , pp. 1249-1250
    • Prockop, D.J.1
  • 44
    • 84873713507 scopus 로고    scopus 로고
    • Multipotent mesenchymal stromal cell therapy and risk of malignancies
    • Casiraghi F, Remuzzi G, Abbate M, Perico N. Multipotent mesenchymal stromal cell therapy and risk of malignancies. Stem Cell Rev. 2013;9: 65-79.
    • (2013) Stem Cell Rev , vol.9 , pp. 65-79
    • Casiraghi, F.1    Remuzzi, G.2    Abbate, M.3    Perico, N.4
  • 45
    • 84862835586 scopus 로고    scopus 로고
    • Analysis of tissues following mes-enchymal stromal cell therapy in humans indicate limited long-term engraftment and no ectopic tissue formation
    • von Bahr L, Batsis I, Moll G, et al. Analysis of tissues following mes-enchymal stromal cell therapy in humans indicate limited long-term engraftment and no ectopic tissue formation. Stem Cells. 2012;30: 1575-1578.
    • (2012) Stem Cells , vol.30 , pp. 1575-1578
    • von Bahr, L.1    Batsis, I.2    Moll, G.3
  • 46
    • 84862296213 scopus 로고    scopus 로고
    • Mesenchymal stromal cells do not increase the risk of viral reactivation nor the severity of viral events in recipients of allogeneic stem cell transplantation
    • Lucchini G, Dander E, Pavan F, et al. Mesenchymal stromal cells do not increase the risk of viral reactivation nor the severity of viral events in recipients of allogeneic stem cell transplantation. Stem Cells Int. 2012;2012:690236.
    • (2012) Stem Cells Int , vol.2012 , pp. 690236
    • Lucchini, G.1    Dander, E.2    Pavan, F.3
  • 47
    • 85027941877 scopus 로고    scopus 로고
    • Human but not murine multipo-tent mesenchymal stromal cells exhibit broad-spectrum antimicrobial effector function mediated by indoleamine 2,3-dioxygenase
    • Meisel R, Brockers S, Heseler K, et al. Human but not murine multipo-tent mesenchymal stromal cells exhibit broad-spectrum antimicrobial effector function mediated by indoleamine 2,3-dioxygenase. Leukemia. 2011;25:648-654.
    • (2011) Leukemia , vol.25 , pp. 648-654
    • Meisel, R.1    Brockers, S.2    Heseler, K.3
  • 48
    • 84893510346 scopus 로고    scopus 로고
    • Cell therapy with autologous mesenchy-mal stem cells - how the disease process impacts clinical considerations
    • Wang J, Liao L, Wang S, Tan J. Cell therapy with autologous mesenchy-mal stem cells - how the disease process impacts clinical considerations. Cytotherapy. 2013;15:893-904.
    • (2013) Cytotherapy , vol.15 , pp. 893-904
    • Wang, J.1    Liao, L.2    Wang, S.3    Tan, J.4
  • 49
    • 2342482526 scopus 로고    scopus 로고
    • Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells
    • Le Blanc K, Rasmusson I, Sundberg B, et al. Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells. Lancet. 2004;363:1439-1441.
    • (2004) Lancet , vol.363 , pp. 1439-1441
    • Le Blanc, K.1    Rasmusson, I.2    Sundberg, B.3
  • 50
    • 43049103438 scopus 로고    scopus 로고
    • Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: A phase II study
    • Le Blanc K, Frassoni F, Ball L, et al. Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study. Lancet. 2008;371:1579-1586.
    • (2008) Lancet , vol.371 , pp. 1579-1586
    • Le Blanc, K.1    Frassoni, F.2    Ball, L.3
  • 51
    • 84896888257 scopus 로고    scopus 로고
    • Efficacy and safety of adult human mesenchymal stem cells to treat steroid refractory acute graft versus host disease
    • ClinicalTrials.Gov, Accessed December 22
    • ClinicalTrials.Gov. Efficacy and safety of adult human mesenchymal stem cells to treat steroid refractory acute graft versus host disease. Osiris Therapeutics. Available from: http://www.clinicaltrials.gov/ct2/show/NCT00366145?term=mesenchymal+stem+cells+AND+bone+marrow+transplantation&rank=16. Accessed December 22, 2013.
    • (2013) Osiris Therapeutics
  • 52
    • 84875468183 scopus 로고    scopus 로고
    • The mesenchymal stromal cells dilemma-does a negative phase III trial of random donor mesenchymal stromal cells in steroid-resistant graft-versus-host disease represent a death knell or a bump in the road?
    • Galipeau J. The mesenchymal stromal cells dilemma-does a negative phase III trial of random donor mesenchymal stromal cells in steroid-resistant graft-versus-host disease represent a death knell or a bump in the road? Cytotherapy. 2013;15:2-8.
    • (2013) Cytotherapy , vol.15 , pp. 2-8
    • Galipeau, J.1
  • 53
    • 84855552728 scopus 로고    scopus 로고
    • Multipotent mesenchymal stromal cells for the prophylaxis of acute graft-versus-host disease - a Phase II study
    • Kuzmina LA, Petinati NA, Parovichnikova EN, et al. Multipotent mesenchymal stromal cells for the prophylaxis of acute graft-versus-host disease - a Phase II study. Stem Cells Int. 2012;2012:968213.
    • (2012) Stem Cells Int , vol.2012 , pp. 968213
    • Kuzmina, L.A.1    Petinati, N.A.2    Parovichnikova, E.N.3
  • 55
    • 33746889097 scopus 로고    scopus 로고
    • Role for interferon-gamma in the immunomodulatory activity of human bone marrow mesenchymal stem cells
    • Krampera M, Cosmi L, Angeli R, et al. Role for interferon-gamma in the immunomodulatory activity of human bone marrow mesenchymal stem cells. Stem Cells. 2006;24:386-398.
    • (2006) Stem Cells , vol.24 , pp. 386-398
    • Krampera, M.1    Cosmi, L.2    Angeli, R.3
  • 56
    • 80052487336 scopus 로고    scopus 로고
    • Mesenchymal stromal cell 'licensing': A multistep process
    • Krampera M. Mesenchymal stromal cell 'licensing': a multistep process. Leukemia. 2011;25:1408-1414.
    • (2011) Leukemia , vol.25 , pp. 1408-1414
    • Krampera, M.1
  • 57
    • 75949085506 scopus 로고    scopus 로고
    • Efficacy of bone marrow-derived mesenchymal stem cells in the treatment of sclerodermatous chronic graft-versus-host disease: Clinical report
    • Zhou H, Guo M, Bian C, et al. Efficacy of bone marrow-derived mesenchymal stem cells in the treatment of sclerodermatous chronic graft-versus-host disease: clinical report. Biol Blood Marrow Transplant. 2010;16:403-412.
    • (2010) Biol Blood Marrow Transplant , vol.16 , pp. 403-412
    • Zhou, H.1    Guo, M.2    Bian, C.3
  • 58
    • 84870606505 scopus 로고    scopus 로고
    • Mesenchymal stromal cells treatment attenuates dry eye in patients with chronic graft-versus-host disease
    • Weng J, He C, Lai P, et al. Mesenchymal stromal cells treatment attenuates dry eye in patients with chronic graft-versus-host disease. Mol Ther. 2012;20:2347-2354.
    • (2012) Mol Ther , vol.20 , pp. 2347-2354
    • Weng, J.1    He, C.2    Lai, P.3
  • 59
    • 77956052070 scopus 로고    scopus 로고
    • Defining the risks of mesenchymal stromal cell therapy
    • Prockop DJ, Brenner M, Fibbe WE, et al. Defining the risks of mesenchymal stromal cell therapy. Cytotherapy. 2010;12:576-578.
    • (2010) Cytotherapy , vol.12 , pp. 576-578
    • Prockop, D.J.1    Brenner, M.2    Fibbe, W.E.3
  • 60
    • 84877938781 scopus 로고    scopus 로고
    • Clinical-grade mesenchymal stromal cells produced under various good manufacturing practice processes differ in their immunomodulatory properties: Standardization of immune quality controls
    • Menard C, Pacelli L, Bassi G, et al. Clinical-grade mesenchymal stromal cells produced under various good manufacturing practice processes differ in their immunomodulatory properties: standardization of immune quality controls. Stem Cells Dev. 2013;22:1789-1801.
    • (2013) Stem Cells Dev , vol.22 , pp. 1789-1801
    • Menard, C.1    Pacelli, L.2    Bassi, G.3
  • 61
    • 34249290744 scopus 로고    scopus 로고
    • Recent advances into the understanding of mesenchymal stem cell traffcking
    • Fox JM, Chamberlain G, Ashton BA, Middleton J. Recent advances into the understanding of mesenchymal stem cell traffcking. Br J Haematol. 2007;137:491-502.
    • (2007) Br J Haematol , vol.137 , pp. 491-502
    • Fox, J.M.1    Chamberlain, G.2    Ashton, B.A.3    Middleton, J.4
  • 62
    • 77958572322 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Mechanisms of immunomodulation and homing
    • Yagi H, Soto-Gutierrez A, Parekkadan B, et al. Mesenchymal stem cells: mechanisms of immunomodulation and homing. Cell Transplant. 2010;19:667-679.
    • (2010) Cell Transplant , vol.19 , pp. 667-679
    • Yagi, H.1    Soto-Gutierrez, A.2    Parekkadan, B.3
  • 63
    • 84862696059 scopus 로고    scopus 로고
    • Mesenchymal stromal cell therapy for steroid-refractory acute and chronic graft versus host disease: A phase 1 study
    • Herrmann R, Sturm M, Shaw K, et al. Mesenchymal stromal cell therapy for steroid-refractory acute and chronic graft versus host disease: a phase 1 study. Int J Hematol. 2012;95:182-188.
    • (2012) Int J Hematol , vol.95 , pp. 182-188
    • Herrmann, R.1    Sturm, M.2    Shaw, K.3
  • 64
    • 84890190232 scopus 로고    scopus 로고
    • A Phase 2 study of allogeneic mesenchymal stromal cells for luminal Crohn's disease refractory to biologic therapy
    • Forbes GM, Sturm MJ, Leong RW, et al. A Phase 2 study of allogeneic mesenchymal stromal cells for luminal Crohn's disease refractory to biologic therapy. Clin Gastroenterol Hepatol. 2014;12:64-71.
    • (2014) Clin Gastroenterol Hepatol , vol.12 , pp. 64-71
    • Forbes, G.M.1    Sturm, M.J.2    Leong, R.W.3
  • 65
    • 33744913533 scopus 로고    scopus 로고
    • Mesenchymal stem cells for treatment of therapy-resistant graft-versus-host disease
    • Ringden O, Uzunel M, Rasmusson I, et al. Mesenchymal stem cells for treatment of therapy-resistant graft-versus-host disease. Transplantation. 2006;81:1390-1397.
    • (2006) Transplantation , vol.81 , pp. 1390-1397
    • Ringden, O.1    Uzunel, M.2    Rasmusson, I.3
  • 66
    • 37049028974 scopus 로고    scopus 로고
    • Favorable response to human adipose tissue-derived mesenchymal stem cells in steroid-refractory acute graft-versus-host disease
    • Fang B, Song Y, Liao L, Zhang Y, Zhao RC. Favorable response to human adipose tissue-derived mesenchymal stem cells in steroid-refractory acute graft-versus-host disease. Transplant Proc. 2007;39: 3358-3362.
    • (2007) Transplant Proc , vol.39 , pp. 3358-3362
    • Fang, B.1    Song, Y.2    Liao, L.3    Zhang, Y.4    Zhao, R.C.5
  • 67
    • 60349129494 scopus 로고    scopus 로고
    • Treatment of refractory acute GVHD with third-party MSC expanded in platelet lysate-containing medium
    • von Bonin M, Stolzel F, Goedecke A, et al. Treatment of refractory acute GVHD with third-party MSC expanded in platelet lysate-containing medium. Bone Marrow Transplant. 2009;43:245-251.
    • (2009) Bone Marrow Transplant , vol.43 , pp. 245-251
    • von Bonin, M.1    Stolzel, F.2    Goedecke, A.3
  • 68
    • 67149093649 scopus 로고    scopus 로고
    • Adult human mesenchymal stem cells added to corticosteroid therapy for the treatment of acute graft-versus-host disease
    • Kebriaei P, Isola L, Bahceci E, et al. Adult human mesenchymal stem cells added to corticosteroid therapy for the treatment of acute graft-versus-host disease. Biol Blood Marrow Transplant. 2009;15: 804-811.
    • (2009) Biol Blood Marrow Transplant , vol.15 , pp. 804-811
    • Kebriaei, P.1    Isola, L.2    Bahceci, E.3
  • 69
    • 79959932280 scopus 로고    scopus 로고
    • Mesenchymal stem cells expanded in vitro with human serum for the treatment of acute and chronic graft-versus-host disease: Results of a phase I/II clinical trial
    • Perez-Simon JA, Lopez-Villar O, Andreu EJ, et al. Mesenchymal stem cells expanded in vitro with human serum for the treatment of acute and chronic graft-versus-host disease: results of a phase I/II clinical trial. Haematologica. 2011;96:1072-1076.
    • (2011) Haematologica , vol.96 , pp. 1072-1076
    • Perez-Simon, J.A.1    Lopez-Villar, O.2    Andreu, E.J.3
  • 70
    • 84882246890 scopus 로고    scopus 로고
    • Unrelated allogeneic bone marrow-derived mesenchymal stem cells for steroid-refractory acute graft-versus-host disease: A phase I/II study
    • Muroi K, Miyamura K, Ohashi K, et al. Unrelated allogeneic bone marrow-derived mesenchymal stem cells for steroid-refractory acute graft-versus-host disease: a phase I/II study. Int J Hematol. 2013;98: 206-213.
    • (2013) Int J Hematol , vol.98 , pp. 206-213
    • Muroi, K.1    Miyamura, K.2    Ohashi, K.3
  • 71
    • 75649105772 scopus 로고    scopus 로고
    • Mesenchymal stem cells for treatment of steroid-resistant chronic graft-versus-host disease
    • Chinese
    • Zhang LS, Liu QF, Huang K, Zhang Y, Fan ZP, Huang SL. Mesenchymal stem cells for treatment of steroid-resistant chronic graft-versus-host disease. Zhonghua Nei Ke Za Zhi. 2009;48:542-546. Chinese.
    • (2009) Zhonghua Nei Ke Za Zhi , vol.48 , pp. 542-546
    • Zhang, L.S.1    Liu, Q.F.2    Huang, K.3    Zhang, Y.4    Fan, Z.P.5    Huang, S.L.6
  • 72
    • 78650208987 scopus 로고    scopus 로고
    • Mesenchymal stem cell as salvage treatment for refractory chronic GVHD
    • Weng JY, Du X, Geng SX, et al. Mesenchymal stem cell as salvage treatment for refractory chronic GVHD. Bone Marrow Transplant. 2010;45:1732-1740.
    • (2010) Bone Marrow Transplant , vol.45 , pp. 1732-1740
    • Weng, J.Y.1    Du, X.2    Geng, S.X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.