Hypoxia enhances the senescence effect of bortezomib - The proteasome inhibitor - On human skin fibroblasts

BioMed Research International

Volumn 2014, Issue , 2014, Pages

  Krȩtowski, Rafał ^a   Borzym Kluczyk, Małgorzata ^a   Cechowska Pasko, Marzanna ^a  

^a MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

BORTEZOMIB; OXYGEN REGULATED PROTEIN 150; BETA GALACTOSIDASE; BORONIC ACID DERIVATIVE; HEAT SHOCK PROTEIN 70; HIF1A PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; OXYGEN-REGULATED PROTEINS; PROTEASOME INHIBITOR; PYRAZINE DERIVATIVE;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL LINE; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; ENVIRONMENTAL STRESS; HUMAN; HUMAN CELL; HYPOXIA; IC 50; INCUBATION TIME; NORMAL HUMAN; PROTEIN EXPRESSION; PROTEIN INDUCTION; SENESCENCE; SKIN FIBROBLAST; CELL AGING; CELL HYPOXIA; CELL SURVIVAL; CYTOLOGY; DRUG EFFECTS; ENZYMOLOGY; FIBROBLAST; METABOLISM; SKIN; WESTERN BLOTTING;

APOPTOSIS; BETA-GALACTOSIDASE; BLOTTING, WESTERN; BORONIC ACIDS; CELL AGING; CELL HYPOXIA; CELL SURVIVAL; FIBROBLASTS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; PROTEASOME INHIBITORS; PYRAZINES; SKIN;

EID: 84896895421     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2014/196249     Document Type: Article

References (42)

1. Zhang X. D., Hersey P., Tay K. H., Tseng H. Y., Jiang C. C., Dong L., Cao M. Y., Adaptation to ER stress as a mechanism of resistance of melanoma to treatment. Current Management of Malignant Melanoma 2011 Rijeka, Croatia InTech
2. Kusaczuk M., Cechowska-Pasko M., Molecular chaperone ORP150 in ER stress-related diseases. Current Pharmaceutical Design 2013 19 15 2807 2818 10.2174/1381612811319150016
3. Tamatani M., Matsuyama T., Yamaguchi A., Mitsuda N., Tsukamoto Y., Taniguchi M., Che Y. H., Ozawa K., Hori O., Nishimura H., Yamashita A., Okabe M., Yanagi H., Stern D. M., Ogawa S., Tohyama M., ORP150 protects against hypoxia/ischemia-induced neuronal death. Nature Medicine 2001 7 3 317 323 2-s2.0-0035108699 10.1038/85463
4. Ma Y., Hendershot L. M., The unfolding tale of the unfolded protein response. Cell 2001 107 7 827 830 2-s2.0-0035966320 10.1016/S0092-8674(01)00623- 7
5. Harding H. P., Calfon M., Urano F., Novoa I., Ron D., Transcriptional and translational control in the mammalian unfolded protein response. Annual Review of Cell and Developmental Biology 2002 18 575 599 2-s2.0-0036437307 10.1146/annurev.cellbio.18.011402.160624
6. Kaufman R. J., Scheuner D., Schröder M., Shen X., Lee K., Liu C. Y., Arnold S. M., The unfolded protein response in nutrient sensing and differentiation. Nature Reviews Molecular Cell Biology 2002 3 6 411 421 2-s2.0-0036086064 10.1038/nrm829
7. Yoshida H., ER stress and diseases. FEBS Journal 2007 274 3 630 658 2-s2.0-33846548110 10.1111/j.1742-4658.2007.05639.x
8. Crawford L. J., Irvine A. E., Gupta A., Proteasome inhibitors in the treatment of multiple myeloma. Multiple Myeloma-An Overview 2012 Rijeka, Croatia InTech
9. Ruschak A. M., Slassi M., Kay L. E., Schimmer A. D., Novel proteasome inhibitors to overcome bortezomib resistance. Journal of the National Cancer Institute 2011 103 13 1007 1017 2-s2.0-79960208716 10.1093/jnci/djr160
10. Frankland-Searby S., Bhaumik S. R., The 26 S proteasome complex: an attractive target for cancer therapy. Biochimica et Biophysica Acta 2012 1825 1 64 76 2-s2.0-81255179936 10.1016/j.bbcan.2011.10.003
11. Fribley A., Wang C., Proteasome inhibitor induces apoptosis through induction of endoplasmic reticulum stress. Cancer Biology and Therapy 2006 5 7 745 748 2-s2.0-33751189389
12. Han Y. H., Kim S. Z., Kim S. H., Park W. H., Reactive oxygen species and glutathione level changes by a proteasome inhibitor, MG132, partially affect calf pulmonary arterial endothelial cell death. Drug and Chemical Toxicology 2010 33 4 403 409 2-s2.0-77956165394 10.3109/01480540903524350
13. Han Y. H., Park W. H., The changes of reactive oxygen species and glutathione by MG132, a proteasome inhibitor affect As4.1 juxtaglomerular cell growth and death. Chemico-Biological Interactions 2010 184 3 319 327 2-s2.0-77949915298 10.1016/j.cbi.2010.01.033
14. Milani M., Rzymski T., Mellor H. R., Pike L., Bottini A., Generali D., Harris A. L., The role of ATF4 stabilization and autophagy in resistance of breast cancer cells treated with Bortezomib. Cancer Research 2009 69 10 4415 4423 2-s2.0-66249085237 10.1158/0008-5472.CAN-08-2839
15. Jänen S. B., Chaachouay H., Richter-Landsberg C., Autophagy is activated by proteasomal inhibition and involved in aggresome clearance in cultured astrocytes. GLIA 2010 58 14 1766 1774 2-s2.0-78349276861 10.1002/glia.21047
16. Ding W. X., Ni H. M., Gao W., Yoshimori T., Stolz D. B., Ron D., Yin X., Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability. American Journal of Pathology 2007 171 2 513 524 2-s2.0-34548299555 10.2353/ajpath.2007.070188
17. Sherman M., Multhoff G., Heat shock proteins in cancer. Annals of the New York Academy of Sciences 2007 1113 192 201 2-s2.0-35548970287 10.1196/annals.1391.030
18. Saretzki G., Cellular senescence in the development and treatment of cancer. Current Pharmaceutical Design 2010 16 1 79 100 2-s2.0-77949449274 10.2174/138161210789941874
19. Chang B. D., Broude E. V., Dokmanovic M., Zhu H., Ruth A., Xuan Y., Kandel E. S., Lausch E., Christov K., Roninson I. B., A senescence-like phenotype distinguishes tumor cells that undergo terminal proliferation arrest after exposure to anticancer agents. Cancer Research 1999 59 15 3761 3767 2-s2.0-17444388849
20. Chang B. D., Xuan Y., Broude E. V., Zhu H., Schott B., Fang J., Roninson I. B., Role of p53 and p21(waf1/cip1) in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs. Oncogene 1999 18 34 4808 4818 2-s2.0-0033606852 10.1038/sj.onc.1203078
21. Collado M., Blasco M. A., Serrano M., Cellular senescence in cancer and aging. Cell 2007 130 2 223 233 2-s2.0-34447543913 10.1016/j.cell.2007.07.003
22. Dimri G. P., What has senescence got to do with cancer? Cancer Cell 2005 7 6 505 512 2-s2.0-20444370974 10.1016/j.ccr.2005.05.025
23. Palaniyappan A., Cyclophosphamide induces premature senescence in normal human fibroblasts by activating MAP kinases. Biogerontology 2009 10 6 677 682 2-s2.0-71349084136 10.1007/s10522-009-9215-5
24. Roninson I. B., Tumor cell senescence in cancer treatment. Cancer Research 2003 63 11 2705 2715 2-s2.0-0038277105
25. Sõti C., Sreedhar A. S., Csermely P., Apoptosis, necrosis and cellular senescence: chaperone occupancy as a potential switch. Aging Cell 2003 2 1 39 45 2-s2.0-0042330311
26. Carmichael J., DeGraff W. G., Gazdar A. F., Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing. Cancer Research 1987 47 4 936 942 2-s2.0-0023130372
27. Laemmli U. K., Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970 227 5259 680 685 2-s2.0-0014949207 10.1038/227680a0
28. Smith P. K., Krohn R. I., Hermanson G. T., Measurement of protein using bicinchoninic acid. Analytical Biochemistry 1985 150 1 76 85 2-s2.0-0022186670
29. Luster T. A., Carrell J. A., McCormick K., Sun D., Humphreys R., Mapatumumab and lexatumumab induce apoptosis in TRAIL-R1 and TRAIL-R2 antibody-resistant NSCLC cell lines when treated in combination with bortezomib. Molecular Cancer Therapeutics 2009 8 2 292 302 2-s2.0-60849086467 10.1158/1535-7163.MCT-08-0918
30. Obeng E. A., Carlson L. M., Gutman D. M., Harrington W. J. Jr., Lee K. P., Boise L. H., Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells. Blood 2006 107 12 4907 4916 2-s2.0-33744539521 10.1182/blood-2005-08-3531
31. Nawrocki S. T., Carew J. S., Pino M. S., Highshaw R. A., Dunner K. Jr., Huang P., Abbruzzese J. L., McConkey D. J., Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis. Cancer Research 2005 65 24 11658 11666 2-s2.0-29244454269 10.1158/0008-5472.CAN-05-2370
32. Fribley A., Wang C. Y., Proteasome inhibitor induces apoptosis through induction of endoplasmic reticulum stress. Cancer Biology and Therapy 2006 5 7 745 748 2-s2.0-33751189389
33. Morgillo F., D'Aiuto E., Troiani T., Martinelli E., Cascone T., De Palma R., Orditura M., De Vita F., Ciardiello F., Antitumor activity of bortezomib in human cancer cells with acquired resistance to anti-epidermal growth factor receptor tyrosine kinase inhibitors. Lung Cancer 2011 71 3 283 290 2-s2.0-79851516240 10.1016/j.lungcan.2010.06.005
34. Laussmann M. A., Passante E., Düssmann H., Rauen J. A., Würstle M. L., Delgado M. E., Devocelle M., Prehn J. H. M., Rehm M., Proteasome inhibition can induce an autophagy-dependent apical activation of caspase-8. Cell Death and Differentiation 2011 18 10 1584 1597 2-s2.0-80052750534 10.1038/cdd.2011.27
35. Brenner D., Mak T. W., Mitochondrial cell death effectors. Current Opinion in Cell Biology 2009 21 6 871 877 2-s2.0-70549107710 10.1016/j.ceb.2009.09.004
36. Qin J. Z., Ziffra J., Stennett L., Bodner B., Bonish B. K., Chaturvedi V., Bennett F., Pollock P. M., Trent J. M., Hendrix M. J. C., Rizzo P., Miele L., Nickoloff B. J., Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma cells. Cancer Research 2005 65 14 6282 6293 2-s2.0-22244452016 10.1158/0008-5472.CAN-05-0676
37. Gomez-Bougie P., Wuillème-Toumi S., Ménoret E., Trichet V., Robillard N., Philippe M., Bataille R., Amiot M., Noxa up-regulation and Mcl-1 cleavage are associated to apoptosis induction by bortezomib in multiple myeloma. Cancer Research 2007 67 11 5418 5424 2-s2.0-34347256390 10.1158/0008-5472.CAN-06-4322
38. Nikiforov M. A., Riblett M., Tang W., Gratchouck V., Zhuang D., Fernandez Y., Verhaegen M., Varambally S., Chinnaiyan A. M., Jakubowiak A. J., Soengas M. S., Tumor cell-selective regulation of NOXA by c-MYC in response to proteasome inhibition. Proceedings of the National Academy of Sciences of the United States of America 2007 104 49 19488 19493 2-s2.0-37649000950 10.1073/pnas.0708380104
39. Fennell D. A., Chacko A., Mutti L., BCL-2 family regulation by the 20 S proteasome inhibitor bortezomib. Oncogene 2008 27 9 1189 1197 2-s2.0-39749136204 10.1038/sj.onc.1210744
40. Mosser D. D., Morimoto R. I., Molecular chaperones and the stress of oncogenesis. Oncogene 2004 23 16 2907 2918 2-s2.0-2342651518 10.1038/sj.onc.1207529
41. Gabai V. L., Yaglom J. A., Waldman T., Sherman M. Y., Heat shock protein Hsp72 controls oncogene-induced senescence pathways in cancer cells. Molecular and Cellular Biology 2009 29 2 559 569 2-s2.0-58249110557 10.1128/MCB.01041-08
42. Cechowska-Pasko M., Bańkowski E., Chene P., The effect of hypoxia on the expression of 150 kDa oxygen-regulated protein (ORP 150) in HeLa cells. Cellular Physiology and Biochemistry 2006 17 1-2 89 96 2-s2.0-33645009879 10.1159/000091467