Icariin attenuates angiotensin II-induced hypertrophy and apoptosis in H9c2 cardiomyocytes by inhibiting reactive oxygen species-dependent JNK and p38 pathways

Experimental and Therapeutic Medicine

Volumn 7, Issue 5, 2014, Pages 1116-1122

  Zhou, Heng ^a,b   Yuan, Yuan ^a,b   Liu, Yuan ^a,b   Deng, Wei ^a,b   Zong, Jing ^a,b   Bian, Zhou Yan ^a,b   Dai, Jia ^a,b   Tang, Qi Zhu ^a,b  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

^b WUHAN UNIVERSITY   (China)

Author keywords

Apoptosis; Hypertrophy; Icariin; Mitogen activated protein kinases; Reactive oxygen species

Indexed keywords

ANGIOTENSIN II; ATRIAL NATRIURETIC FACTOR; ATRIAL NATRIURETIC FACTOR B; CASPASE 3; DIMETHYL SULFOXIDE; HYDROGEN PEROXIDE; ICARIIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; NATRIURETIC FACTOR; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CARDIOMYOCYTE; CELL VIABILITY; CONTROLLED STUDY; EPIMEDIUM; FLUORESCENCE MICROSCOPE; HEART MUSCLE CELL; HYPERTROPHY; IN VITRO STUDY; INTRACELLULAR SIGNALING; MICROPLATE READER; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 84896882638     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2014.1598     Document Type: Article

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