Grape seed proanthocyanidin extract prevents DDP-induced testicular toxicity in rats

Food and Function

Volumn 5, Issue 3, 2014, Pages 605-611

  Zhao, Yan Meng ^a   Gao, Li Ping ^a   Zhang, Hai Lian ^a   Guo, Jun Xia ^a   Guo, Pei Pei ^a  

^a BEIJING UNION UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

FLAVONOIDS; OXIDATIVE STRESS; PLATINUM COMPOUNDS; RATS;

DOSE-DEPENDENT; HARMFUL EFFECTS; INTRAPERITONEAL; LIPID PEROXIDATION; PROANTHOCYANIDINS; PROTECTIVE EFFECTS; REPRODUCTIVE ORGANS; SPERM COUNTS;

TOXICITY;

ANTINEOPLASTIC AGENT; CISPLATIN; GLUTATHIONE; GRAPE SEED EXTRACT; GRAPE SEED PROANTHOCYANIDINS; PROANTHOCYANIDIN;

ANIMAL; ARTICLE; CYTOLOGY; DRUG EFFECT; LIPID PEROXIDATION; MALE; METABOLISM; OXIDATIVE STRESS; RAT; SPERMATOZOON COUNT; SPERMATOZOON MOTILITY; SPRAGUE DAWLEY RAT; TESTIS;

ANIMALS; ANTINEOPLASTIC AGENTS; CISPLATIN; GLUTATHIONE; GRAPE SEED EXTRACT; LIPID PEROXIDATION; MALE; OXIDATIVE STRESS; PROANTHOCYANIDINS; RATS; RATS, SPRAGUE-DAWLEY; SPERM COUNT; SPERM MOTILITY; TESTIS;

EID: 84896869444     PISSN: 20426496     EISSN: 2042650X     Source Type: Journal    
DOI: 10.1039/c3fo60486a     Document Type: Article

References (29)

1. G. M. Colpi G. F. Contalbi F. Nerva P. Sagone G. Piediferro Testicular function following chemo-radiotherapy Eur. J. Obstet. Gynecol. Reprod. Biol. 2004 113 S2 S6
2. S. J. Howell S. M. Shalet Spermatogenesis after cancer treatment: damage and recovery J. Natl. Cancer Inst. Monogr. 2005 34 12 17
3. D. Wang S. J. Lippard Cellular processing of platinum anticancer drugs Nat. Rev. Drug Discovery 2005 4 307 320
4. S. M. Cherry P. A. Hunt T. J. Hassold Cisplatin disrupts mammalian spermatogenesis, but does not affect recombination or chromosome segregation Mutat. Res. 2004 564 115 128
5. T. Ishikawa S. Kamidono M. Fujisawa Fertility after high-dose chemotherapy for testicular cancer Urology 2004 63 137 140
6. E. A. Ahmed H. M. Omar S. K. A. Elghaffar S. M. Ragb A. Y. Nasser The antioxidant activity of vitamin C, DPPD and l-cysteine against cisplatin-induced testicular oxidative damage in rats Food Chem. Toxicol. 2011 49 1115 1121
7. J. M. Pérez-Rojas C. E. Guerrero-Beltrán C. Cruz D. J. Sánchez-González C. M. Martínez-Martínez J. Pedraza-Chaverri Preventive effect of tert-butylhydroquinone on cisplatin-induced nephrotoxicity in rats Food Chem. Toxicol. 2011 49 10 2631 2637
8. Y. I. Chirino J. Pedraza-Chaverri Role of oxidative and nitrosative stress in cisplatin-induced nephrotoxicity Exp. Toxicol. Pathol. 2009 61 3 223 242
9. E. A. Salem N. A. Salem A. M. Maarouf E. C. Serefoglu W. J. G. Hellstrom Selenium and Lycopene Attenuate Cisplatin-induced Testicular Toxicity Associated with Oxidative Stress in Wistar Rats Urology 2012 79 5 1184.e1 1184.e6
10. Y. O. Ilbey E. Ozbek A. Simsek A. Otunctemur M. Cekmen A. Somay Potential chemoprotective effect of melatonin in cyclophosphamide- and cisplatin-induced testicular damage in rats Fertil. Steril. 2009 92 3 1124 1132
11. G. Turk A. Atessahin M. Sonmez et al., Improvement of cisplatin-induced injuries to sperm quality, the oxidant-antioxidant system, and the histologic structure of the rat testis by ellagic acid Fertil. Steril. 2008 89 1474 1481
12. P. Vernet R. J. Aitken J. R. Drevet Antioxidant strategies in the epididymis Mol. Cell. Endocrinol. 2004 216 31 39
13. V. Houde D. Grenier F. Chandad Protective effects of grape seed proanthocyanidins against oxidative stress induced by lipopolysaccharides of periodontopathogens J. Periodontol. 2006 l77 1371 1379
14. Z. H. Shao L. B. Becker T. L. Vanden Hoek P. T. Schumacker C. Q. Li D. Zhao K. Wojcik T. Anderson Y. Qin L. Dey C. S. Yuan Grape seed proanthocyanidin extract attenuates oxidant injury in cardiomyocytes Pharmacol. Res. 2003 47 463 469
15. P. K. Vayalil A. Mittal S. K. Katiyar Proanthocyanidins from grape seeds inhibit expression of matrix metalloproteinases in human prostate carcinoma cells, which is associated with the inhibition of activation of MAPK and NF kappa B Carcinogenesis 2004 25 987 995
16. D. Bagchi A. Garg R. L. Krohn M. Bagchi M. X. Tran S. J. Stohs Oxygen free radical scavenging abilities of vitamins C and E, and a grape seed proanthocyanidin extract in vitro Res. Commun. Mol. Pathol. Pharmacol. 1997 93 179 189
17. M. Sato G. Maulik P. S. Ray D. Bagchi D. K. Das Cardioprotective effects of grape seed proanthocyanidin against ischemic reperfusion injury J. Mol. Cell. Cardiol. 1999 31 1289 1297
18. D. Bagchi A. Garg R. L. Krohn M. Bagchi D. J. Bagchi J. Balmoori S. J. Stohs Protective effects of grape seed proanthocyanidins and selected antioxidants against TPA-induced hepatic and brain lipid peroxidation and DNA fragmentation, and peritoneal macrophage activation in mice Gen. Pharmacol. 1998 30 771 776
19. S. Ray D. Bagchi P. M. Lim M. Bagchi S. M. Gross S. C. Kothari H. G. Preuss S. J. Stohs Acute and long-term safety evaluation of a novel IH636 grape seed proanthocyanidin extract Res. Commun. Mol. Pathol. Pharmacol. 2001 109 165 197
20. M. I. Yousef A. A. Saad L. K. EI-Shennawy Protective effect of grape seed proanthocyanidin extract against oxidative stress induced by cisplatin in rats Food Chem. Toxicol. 2009 47 1176 1183
21. A. S. Abir I. Y. Mokhtar K. E. Lamiaa Cisplatin induced damage in kidney genomic DNA and nephrotoxicity in male rats: the protective effect of grape seed proanthocyanidin extract Food Chem. Toxicol. 2009 47 1499 1506
22. K. Yokoi E. O. Uthus F. H. Nielsen Nickel deficiency diminishes sperm quantity and movement in rats Biol. Trace Elem. Res. 2003 93 141 153
23. A. Ateşşahin I. Karahan G. Turk S. Gür S. Yilmaz A. O. Çeribaşi Protective role of lycopene on cisplatin induced changes in sperm characteristics, testicular damage and oxidative stress in rats Reprod. Toxicol. 2006 21 42 47
24. S. J. Howell S. M. Shalet Testicular function following chemotherapy Hum. Reprod. Update 2001 7 36 39
25. R. H. Martin S. Ernst A. Rademaker L. Barclay E. Ko N. Summer Analysis of sperm chromosome complements before, during, and after chemotherapy Cancer Genet. Cytogenet. 1999 108 133 136
26. K. Boekelheide Mechanisms of toxic damage to spermatogenesis J. Natl. Cancer Inst. Monogr. 2005 34 6 8
27. M. A. Baker R. J. Aitken Reactive oxygen species in spermatozoa: methods for monitoring and significance for the origins of genetic disease and infertility Reprod. Biol. Endocrinol. 2005 3 67
28. D. Bagchi M. Bagchi S. J. Stohs S. D. Ray C. K. Sen H. G. Preuss Cellular protection with proanthocyanidins derived from grape seeds Ann. N. Y. Acad. Sci. 2002 957 260 270
29. M. Gemma B. Isabek V. Josep et al., Atrimer plus a dimer-gallate reproduce the bioactivity described for an extract of grape seed procyanidins Food Chem. 2009 116 265 270