Sedation during noninvasive mechanical ventilation with dexmedetomidine or midazolam: A randomized, double-blind, prospective study

Current Therapeutic Research - Clinical and Experimental

Volumn 71, Issue 3, 2010, Pages 141-153

  Senoglu, Nimet ^a   Oksuz, Hafize ^a   Dogan, Zafer ^a   Yildiz, Huseyin ^a   Demirkiran, Hilmi ^a   Ekerbicer, Hasan ^b  

^a KAHRAMANMARAS SUTCU IMAM UNIVERSITY   (Turkey)

^b Public Health Care Medicine Faculty of Medicine   (Turkey)

Author keywords

Bispectral index; Dexmedetomidine; Mechanical ventilation; Midazolam; Sedation

Indexed keywords

ANTIBIOTIC AGENT; BRONCHODILATING AGENT; DEXMEDETOMIDINE; MIDAZOLAM; MUCOLYTIC AGENT; STEROID;

ACUTE RESPIRATORY FAILURE; ADULT; ARTERIAL GAS; ARTICLE; ARTIFICIAL VENTILATION; BREATHING RATE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE EXACERBATION; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; GAS EXCHANGE; HEART RATE; HEMODYNAMICS; HUMAN; INTENSIVE CARE UNIT; LOADING DRUG DOSE; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEDATION; VITAL SIGN;

EID: 77954693379     PISSN: 0011393X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.curtheres.2010.06.003     Document Type: Article

References (30)

1. Kallet RH Noninvasive ventilation in acute care: Controversies and emerging concepts. Respir Care. 2009, 54:259-263.
2. Girault C, Briel A, Hellot MF, et al. Noninvasive mechanical ventilation in clinical practice: A 2-year experience in a medical intensive care unit. Crit Care Med. 2003, 31:552-559.
3. Nava S, Ceriana P Patient-ventilator interaction during noninvasive positive pressure ventilation. Respir Care Clin N Am. 2005, 11:281-293.
4. Jacobi J, Fraser GL, Coursin DB, et al. Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult [published correction appears in Crit Care Med. 2002;30:726]. Crit Care Med. 2002, 30:119-141. Task Force of the American College of Critical Care Medicine (ACCM) of the Society of Critical Care Medicine (SCCM), American Society of Health-System Pharmacists (ASHP)American Society of Health-System Pharmacists (ASHP), American College of Chest PhysiciansAmerican College of Chest Physicians.
5. Mattia C, Savoia G, Paoletti F, et al. SIAARTI recommendations for analgosedation in intensive care unit [in Italian]. Minerva Anestesiol. 2006, 72:769-805. SIAARTI.
6. Ostermann ME, Keenan SP, Seiferling RA, Sibbald WJ Sedation in the intensive care unit: A systematic review. JAMA. 2000, 283:1451-1459.
7. Izurieta R, Rabatin JT Sedation during mechanical ventilation: A systematic review. Crit Care Med. 2002, 30:2644-2648.
8. Devlin JW, Nava S, Fong JJ, et al. Survey of sedation practices during noninvasive positive-pressure ventilation to treat acute respiratory failure. Crit Care Med. 2007, 35:2298-2302.
9. Akada S, Takeda S, Yoshida Y, et al. The efficacy of dexmedetomidine in patients with noninvasive ventilation: A preliminary study. Anesth Analg. 2008, 107:167-170.
10. Takasaki Y, Kido T, Semba K Dexmedetomidine facilitates induction of noninvasive positive pressure ventilation for acute respiratory failure in patients with severe asthma [publshed correction appears in J Anesth. 2009;23:314]. J Anesth. 2009, 23:147-150.
11. Mehta S, Hill NS Noninvasive ventilation. Am J Respir Crit Care Med. 2001, 163:540-577.
12. Gay PC Complications of noninvasive ventilation in acute care. Respir Care. 2009, 54:246-257.
13. Gay PC Complications of noninvasive ventilation in acute care. Respir Care. 2009, 54:257-258.
14. Triltsch AE, Welte M, von Homeyer P, et al. Bispectral index-guided sedation with dexmedetomidine in intensive care: A prospective, randomized, double blind, placebo-controlled phase II study. Crit Care Med. 2002, 30:1007-1014.
15. Carollo DS, Nossaman BD, Ramadhyani U Dexmedetomidine: A review of clinical applications. Curr Opin Anaesthesiol. 2008, 21:457-461.
16. Gerlach AT, Dasta JF Dexmedetomidine: An updated review [published correction appears in Ann Pharmacother. 2007;41:530-531]. Ann Pharmacother. 2007, 41:245-252.
17. Venn RM, Hell J, Grounds RM Respiratory effects of dexmedetomidine in the surgical patient requiring intensive care. Crit Care. 2000, 4:302-308.
18. Brochard L, Mancebo J, Wysocki M, et al. Noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease. N Engl J Med. 1995, 333:817-822.
19. Plant PK, Owen JL, Elliott MW Early use of non-invasive ventilation for acute exacerbations of chronic obstructive pulmonary disease on general respiratory wards: A multicentre randomised controlled trial. Lancet. 2000, 355:1931-1935.
20. Ramsay M, Savege TM, Simpson BR, Goodwin R Controlled sedation with alphaxalone-alphadolone. Br Med J. 1974, 2:656-659.
21. Riker RR, Picard J, Fraser GL Prospective evaluation of the Sedation-Agitation Scale for adult critically ill patients. Crit Care Med. 1999, 27:1325-1329.
22. Glass PS, Bloom M, Kearse L, et al. Bispectral analysis measures sedation and memory effects of propofol, midazolam, isoflurane, and alfentanil in healthy volunteers. Anesthesiology. 1997, 86:836-847.
23. Hoste EA, Clermont G, Kersten A, et al. RIFLE criteria for acute kidney injury are associated with hospital mortality in critically ill patients: A cohort analysis. Crit Care. 2006, 10:R73.
24. Hoste EA, Clermont G, Kersten A, et al. RIFLE criteria for acute kidney injury are associated with hospital mortality in critically ill patients: A cohort analysis. Crit Care. 2006, 10:1-10.
25. Liu J, Singh H, White PF Electroencephalogram bispectral analysis predicts the depth of midazolam-induced sedation. Anesthesiology. 1996, 84:64-69.
26. Dasta JF, Kane-Gill SL, Durtschi AJ Comparing dexmedetomidine prescribing patterns and safety in the naturalistic setting versus published data. Ann Pharmacother. 2004, 38:1130-1135.
27. Groeben H, Mitzner W, Brown RH Effects of the alpha2-adrenoceptor agonist dexmedetomidine on bronchoconstriction in dogs. Anesthesiology. 2004, 100:359-363.
28. Shelly MP, Sultan MA, Bodenham A, Park GR Midazolam infusions in critically ill patients. Eur J Anaesthesiol. 1991, 8:21-27.
29. Boulieu R, Lehmann B, Salord F, et al. Pharmacokinetics of midazolam and its main metabolite 1-hydroxymidazolam in intensive care patients. Eur J Drug Metab Pharmacokinet. 1998, 23:255-258.
30. Arain SR, Ebert TJ The efficacy, side effects, and recovery characteristics of dexmedetomidine versus propofol when used for intraoperative sedation. Anesth Analg. 2002, 95:461-466. table of contents.