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Volumn 28, Issue 2, 2014, Pages 181-198

Ischemia-reperfusion injury in sickle cell anemia: Relationship to acute chest syndrome, endothelial dysfunction, arterial vasculopathy, and inflammatory pain

Author keywords

Endothelial dysfunction; Inflammation; Ischemia reperfusion; Sickle

Indexed keywords

ACUTE CHEST SYNDROME; BIOMEDICINE; ENVIRONMENTAL STRESS; EPIGENETICS; GENETIC POLYMORPHISM; HEMOLYTIC ANEMIA; HUMAN; INFLAMMATORY PAIN; ISCHEMIC PRECONDITIONING; MICROVASCULATURE; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY; REVIEW; SICKLE CELL ANEMIA; VASCULAR DISEASE; ANIMAL; BIOLOGICAL MODEL; INFLAMMATION; PAIN; PATHOPHYSIOLOGY; VASCULAR ENDOTHELIUM;

EID: 84896849171     PISSN: 08898588     EISSN: 15581977     Source Type: Journal    
DOI: 10.1016/j.hoc.2013.11.005     Document Type: Review
Times cited : (104)

References (90)
  • 1
    • 0034053099 scopus 로고    scopus 로고
    • Pathophysiology of ischaemia-reperfusion injury
    • Carden D.L., Granger D.N. Pathophysiology of ischaemia-reperfusion injury. JPathol 2000, 190:255-266.
    • (2000) JPathol , vol.190 , pp. 255-266
    • Carden, D.L.1    Granger, D.N.2
  • 3
    • 0021984681 scopus 로고
    • Oxygen-derived free radicals in postischemic tissue injury
    • McCord J.M. Oxygen-derived free radicals in postischemic tissue injury. NEngl J Med 1985, 312:159-163.
    • (1985) NEngl J Med , vol.312 , pp. 159-163
    • McCord, J.M.1
  • 4
    • 84856295303 scopus 로고    scopus 로고
    • Role of reactive oxygen and nitrogen species in the vascular responses to inflammation
    • Kvietys P.R., Granger D.N. Role of reactive oxygen and nitrogen species in the vascular responses to inflammation. Free Radic Biol Med 2012, 52:556-592.
    • (2012) Free Radic Biol Med , vol.52 , pp. 556-592
    • Kvietys, P.R.1    Granger, D.N.2
  • 5
    • 34548230927 scopus 로고    scopus 로고
    • Getting to the site of inflammation: the leukocyte adhesion cascade updated
    • Ley K., Laudanna C., Cybulsky M.I., et al. Getting to the site of inflammation: the leukocyte adhesion cascade updated. Nat Rev Immunol 2007, 7:678-689.
    • (2007) Nat Rev Immunol , vol.7 , pp. 678-689
    • Ley, K.1    Laudanna, C.2    Cybulsky, M.I.3
  • 6
    • 0036689830 scopus 로고    scopus 로고
    • NF-kappaB activation and inhibition: a review
    • Sun Z., Andersson R. NF-kappaB activation and inhibition: a review. Shock 2002, 18:99-106.
    • (2002) Shock , vol.18 , pp. 99-106
    • Sun, Z.1    Andersson, R.2
  • 7
    • 67749102142 scopus 로고    scopus 로고
    • Toll-like receptors in ischemia-reperfusion injury
    • Arumugam T.V., Okun E., Tang S.C., et al. Toll-like receptors in ischemia-reperfusion injury. Shock 2009, 32:4-16.
    • (2009) Shock , vol.32 , pp. 4-16
    • Arumugam, T.V.1    Okun, E.2    Tang, S.C.3
  • 8
    • 70350518440 scopus 로고    scopus 로고
    • An emerging role of mast cells in cerebral ischemia and hemorrhage
    • Strbian D., Kovanen P.T., Karjalainen-Lindsberg M.L., et al. An emerging role of mast cells in cerebral ischemia and hemorrhage. Ann Med 2009, 41:438-450.
    • (2009) Ann Med , vol.41 , pp. 438-450
    • Strbian, D.1    Kovanen, P.T.2    Karjalainen-Lindsberg, M.L.3
  • 9
    • 84879175504 scopus 로고    scopus 로고
    • Heme oxygenase-1 and gut ischemia/reperfusion injury: a short review
    • Liao Y.F., Zhu W., Li D.P., et al. Heme oxygenase-1 and gut ischemia/reperfusion injury: a short review. World J Gastroenterol 2013, 19:3555-3561.
    • (2013) World J Gastroenterol , vol.19 , pp. 3555-3561
    • Liao, Y.F.1    Zhu, W.2    Li, D.P.3
  • 10
    • 0026568232 scopus 로고
    • Sepsis and coagulation. An important link
    • Bone R.C. Sepsis and coagulation. An important link. Chest 1992, 101:594-596.
    • (1992) Chest , vol.101 , pp. 594-596
    • Bone, R.C.1
  • 11
    • 84870439456 scopus 로고    scopus 로고
    • Platelets: key players in vascular inflammation
    • Projahn D., Koenen R.R. Platelets: key players in vascular inflammation. JLeukoc Biol 2012, 92:1167-1175.
    • (2012) JLeukoc Biol , vol.92 , pp. 1167-1175
    • Projahn, D.1    Koenen, R.R.2
  • 12
    • 60749137151 scopus 로고    scopus 로고
    • NADPH oxidase-dependent signaling in endothelial cells: role in physiology and pathophysiology
    • Frey R.S., Ushio-Fukai M., Malik A.B. NADPH oxidase-dependent signaling in endothelial cells: role in physiology and pathophysiology. Antioxid Redox Signal 2009, 11:791-810.
    • (2009) Antioxid Redox Signal , vol.11 , pp. 791-810
    • Frey, R.S.1    Ushio-Fukai, M.2    Malik, A.B.3
  • 13
    • 84871887089 scopus 로고    scopus 로고
    • Recoupling the cardiac nitric oxide synthases: tetrahydrobiopterin synthesis and recycling
    • Alkaitis M.S., Crabtree M.J. Recoupling the cardiac nitric oxide synthases: tetrahydrobiopterin synthesis and recycling. Curr Heart Fail Rep 2012, 9:200-210.
    • (2012) Curr Heart Fail Rep , vol.9 , pp. 200-210
    • Alkaitis, M.S.1    Crabtree, M.J.2
  • 15
    • 82855167276 scopus 로고    scopus 로고
    • Shedding of the endothelial glycocalyx in arterioles, capillaries, and venules and its effect on capillary hemodynamics during inflammation
    • Lipowsky H.H., Gao L., Lescanic A. Shedding of the endothelial glycocalyx in arterioles, capillaries, and venules and its effect on capillary hemodynamics during inflammation. Am J Physiol Heart Circ Physiol 2011, 301:H2235-H2245.
    • (2011) Am J Physiol Heart Circ Physiol , vol.301
    • Lipowsky, H.H.1    Gao, L.2    Lescanic, A.3
  • 16
    • 0018846847 scopus 로고
    • Organization of microcirculation in the lung
    • Gil J. Organization of microcirculation in the lung. Annu Rev Physiol 1980, 42:177-186.
    • (1980) Annu Rev Physiol , vol.42 , pp. 177-186
    • Gil, J.1
  • 17
    • 0037378123 scopus 로고    scopus 로고
    • Unique structural features that influence neutrophil emigration into the lung
    • Burns A.R., Smith C.W., Walker D.C. Unique structural features that influence neutrophil emigration into the lung. Physiol Rev 2003, 83:309-336.
    • (2003) Physiol Rev , vol.83 , pp. 309-336
    • Burns, A.R.1    Smith, C.W.2    Walker, D.C.3
  • 18
    • 84865708223 scopus 로고    scopus 로고
    • Remote ischemic preconditioning prevents reduction in brachial artery flow-mediated dilation after strenuous exercise
    • Bailey T.G., Birk G.K., Cable N.T., et al. Remote ischemic preconditioning prevents reduction in brachial artery flow-mediated dilation after strenuous exercise. Am J Physiol Heart Circ Physiol 2012, 303:H533-H538.
    • (2012) Am J Physiol Heart Circ Physiol , vol.303
    • Bailey, T.G.1    Birk, G.K.2    Cable, N.T.3
  • 19
    • 84886297249 scopus 로고    scopus 로고
    • Ischemic preconditioning alters the epigenetic profile of the brain from ischemic intolerance to ischemic tolerance
    • Thompson J.W., Dave K.R., Young J.I., et al. Ischemic preconditioning alters the epigenetic profile of the brain from ischemic intolerance to ischemic tolerance. Neurotherapeutics 2013, 10(4):789-797.
    • (2013) Neurotherapeutics , vol.10 , Issue.4 , pp. 789-797
    • Thompson, J.W.1    Dave, K.R.2    Young, J.I.3
  • 20
    • 78149362183 scopus 로고    scopus 로고
    • Postconditioning in reperfusion injury: a status report (invited review)
    • Zhao Z.Q. Postconditioning in reperfusion injury: a status report (invited review). Cardiovasc Drugs Ther 2010, 24:265-279.
    • (2010) Cardiovasc Drugs Ther , vol.24 , pp. 265-279
    • Zhao, Z.Q.1
  • 21
    • 81255195550 scopus 로고    scopus 로고
    • Ischemia and reperfusion-from mechanism to translation
    • Eltzschig H.K., Eckle T. Ischemia and reperfusion-from mechanism to translation. Nat Med 2011, 17:1391-1401.
    • (2011) Nat Med , vol.17 , pp. 1391-1401
    • Eltzschig, H.K.1    Eckle, T.2
  • 22
    • 34548746306 scopus 로고    scopus 로고
    • Myocardial reperfusion injury
    • Yellon D.M., Hausenloy D.J. Myocardial reperfusion injury. NEngl J Med 2007, 357:1121-1135.
    • (2007) NEngl J Med , vol.357 , pp. 1121-1135
    • Yellon, D.M.1    Hausenloy, D.J.2
  • 23
    • 84882759058 scopus 로고    scopus 로고
    • Oxidative stress and pathophysiology of ischemic stroke: novel therapeutic opportunities
    • Rodrigo R., Fernandez-Gajardo R., Gutierrez R., et al. Oxidative stress and pathophysiology of ischemic stroke: novel therapeutic opportunities. CNS Neurol Disord Drug Targets 2013, 12:698-714.
    • (2013) CNS Neurol Disord Drug Targets , vol.12 , pp. 698-714
    • Rodrigo, R.1    Fernandez-Gajardo, R.2    Gutierrez, R.3
  • 24
    • 78650945976 scopus 로고    scopus 로고
    • Intestinal ischemia/reperfusion: microcirculatory pathology and functional consequences
    • Vollmar B., Menger M.D. Intestinal ischemia/reperfusion: microcirculatory pathology and functional consequences. Langenbecks Arch Surg 2011, 396:13-29.
    • (2011) Langenbecks Arch Surg , vol.396 , pp. 13-29
    • Vollmar, B.1    Menger, M.D.2
  • 25
    • 0033624253 scopus 로고    scopus 로고
    • Hypoxia/reoxygenation causes inflammatory response in transgenic sickle mice but not in normal mice
    • Kaul D.K., Hebbel R.P. Hypoxia/reoxygenation causes inflammatory response in transgenic sickle mice but not in normal mice. JClin Invest 2000, 106:411-420.
    • (2000) JClin Invest , vol.106 , pp. 411-420
    • Kaul, D.K.1    Hebbel, R.P.2
  • 26
    • 0037588990 scopus 로고    scopus 로고
    • Transgenic sickle mice have vascular inflammation
    • Belcher J.D., Bryant C.J., Nguyen J., et al. Transgenic sickle mice have vascular inflammation. Blood 2003, 101:3953-3959.
    • (2003) Blood , vol.101 , pp. 3953-3959
    • Belcher, J.D.1    Bryant, C.J.2    Nguyen, J.3
  • 27
    • 0034235705 scopus 로고    scopus 로고
    • Reperfusion injury pathophysiology in sickle transgenic mice
    • Osarogiagbon U.R., Choong S., Belcher J.D., et al. Reperfusion injury pathophysiology in sickle transgenic mice. Blood 2000, 96:314-320.
    • (2000) Blood , vol.96 , pp. 314-320
    • Osarogiagbon, U.R.1    Choong, S.2    Belcher, J.D.3
  • 28
    • 33751530487 scopus 로고    scopus 로고
    • Protective effect of arginine on oxidative stress in transgenic sickle mouse models
    • Dasgupta T., Hebbel R.P., Kaul D.K. Protective effect of arginine on oxidative stress in transgenic sickle mouse models. Free Radic Biol Med 2006, 41:1771-1780.
    • (2006) Free Radic Biol Med , vol.41 , pp. 1771-1780
    • Dasgupta, T.1    Hebbel, R.P.2    Kaul, D.K.3
  • 29
    • 35348950927 scopus 로고    scopus 로고
    • Redox-dependent impairment of vascular function in sickle cell disease
    • Aslan M., Freeman B.A. Redox-dependent impairment of vascular function in sickle cell disease. Free Radic Biol Med 2007, 43:1469-1483.
    • (2007) Free Radic Biol Med , vol.43 , pp. 1469-1483
    • Aslan, M.1    Freeman, B.A.2
  • 30
    • 0037986617 scopus 로고    scopus 로고
    • L-4F, an apolipoprotein A-1 mimetic, dramatically improves vasodilation in hypercholesterolemia and sickle cell disease
    • Ou J., Ou Z., Jones D.W., et al. L-4F, an apolipoprotein A-1 mimetic, dramatically improves vasodilation in hypercholesterolemia and sickle cell disease. Circulation 2003, 107:2337-2341.
    • (2003) Circulation , vol.107 , pp. 2337-2341
    • Ou, J.1    Ou, Z.2    Jones, D.W.3
  • 31
    • 78650419600 scopus 로고    scopus 로고
    • P-selectin-mediated platelet-neutrophil aggregate formation activates neutrophils in mouse and human sickle cell disease
    • Polanowska-Grabowska R., Wallace K., Field J.J., et al. P-selectin-mediated platelet-neutrophil aggregate formation activates neutrophils in mouse and human sickle cell disease. Arterioscler Thromb Vasc Biol 2010, 30:2392-2399.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 2392-2399
    • Polanowska-Grabowska, R.1    Wallace, K.2    Field, J.J.3
  • 32
    • 0035312965 scopus 로고    scopus 로고
    • Modulation of endothelial cell activation in sickle cell disease: a pilot study
    • Solovey A.A., Solovey A.N., Harkness J., et al. Modulation of endothelial cell activation in sickle cell disease: a pilot study. Blood 2001, 97:1937-1941.
    • (2001) Blood , vol.97 , pp. 1937-1941
    • Solovey, A.A.1    Solovey, A.N.2    Harkness, J.3
  • 33
    • 3242774630 scopus 로고    scopus 로고
    • Endothelial cell expression of tissue factor in sickle mice is augmented by hypoxia/reoxygenation and inhibited by lovastatin
    • Solovey A., Kollander R., Shet A., et al. Endothelial cell expression of tissue factor in sickle mice is augmented by hypoxia/reoxygenation and inhibited by lovastatin. Blood 2004, 104:840-846.
    • (2004) Blood , vol.104 , pp. 840-846
    • Solovey, A.1    Kollander, R.2    Shet, A.3
  • 34
    • 84875475916 scopus 로고    scopus 로고
    • Hemopexin therapy improves cardiovascular function by preventing heme-induced endothelial toxicity in mouse models of hemolytic diseases
    • Vinchi F., De Franceschi L., Ghigo A., et al. Hemopexin therapy improves cardiovascular function by preventing heme-induced endothelial toxicity in mouse models of hemolytic diseases. Circulation 2013, 127:1317-1329.
    • (2013) Circulation , vol.127 , pp. 1317-1329
    • Vinchi, F.1    De Franceschi, L.2    Ghigo, A.3
  • 35
    • 49849101277 scopus 로고    scopus 로고
    • Arginine therapy of transgenic-knockout sickle mice improves microvascular function by reducing non-nitric oxide vasodilators, hemolysis, and oxidative stress
    • Kaul D.K., Zhang X., Dasgupta T., et al. Arginine therapy of transgenic-knockout sickle mice improves microvascular function by reducing non-nitric oxide vasodilators, hemolysis, and oxidative stress. Am J Physiol Heart Circ Physiol 2008, 295:H39-H47.
    • (2008) Am J Physiol Heart Circ Physiol , vol.295
    • Kaul, D.K.1    Zhang, X.2    Dasgupta, T.3
  • 36
    • 0033637285 scopus 로고    scopus 로고
    • Mechanisms of vascular instability in a transgenic mouse model of sickle cell disease
    • Nath K.A., Shah V., Haggard J.J., et al. Mechanisms of vascular instability in a transgenic mouse model of sickle cell disease. Am J Physiol Regul Integr Comp Physiol 2000, 279:R1949-R1955.
    • (2000) Am J Physiol Regul Integr Comp Physiol , vol.279
    • Nath, K.A.1    Shah, V.2    Haggard, J.J.3
  • 37
    • 0033921542 scopus 로고    scopus 로고
    • Impaired nitric oxide-mediated vasodilation in transgenic sickle mouse
    • Kaul D.K., Liu X.D., Fabry M.E., et al. Impaired nitric oxide-mediated vasodilation in transgenic sickle mouse. Am J Physiol Heart Circ Physiol 2000, 278:H1799-H1806.
    • (2000) Am J Physiol Heart Circ Physiol , vol.278
    • Kaul, D.K.1    Liu, X.D.2    Fabry, M.E.3
  • 38
    • 4644226872 scopus 로고    scopus 로고
    • Microvascular blood flow and stasis in transgenic sickle mice: utility of a dorsal skin fold chamber for intravital microscopy
    • Kalambur V.S., Mahaseth H., Bischof J.C., et al. Microvascular blood flow and stasis in transgenic sickle mice: utility of a dorsal skin fold chamber for intravital microscopy. Am J Hematol 2004, 77:117-125.
    • (2004) Am J Hematol , vol.77 , pp. 117-125
    • Kalambur, V.S.1    Mahaseth, H.2    Bischof, J.C.3
  • 39
    • 21144440415 scopus 로고    scopus 로고
    • Critical role of endothelial cell activation in hypoxia-induced vasoocclusion in transgenic sickle mice
    • Belcher J.D., Mahaseth H., Welch T.E., et al. Critical role of endothelial cell activation in hypoxia-induced vasoocclusion in transgenic sickle mice. Am J Physiol Heart Circ Physiol 2005, 288:H2715-H2725.
    • (2005) Am J Physiol Heart Circ Physiol , vol.288
    • Belcher, J.D.1    Mahaseth, H.2    Welch, T.E.3
  • 40
    • 84880517586 scopus 로고    scopus 로고
    • Hypoxia/reoxygenation stress increases markers of vaso-occlusive crisis in sickle SAD mice
    • Aufradet E., DeSouza G., Bourgeaux V., et al. Hypoxia/reoxygenation stress increases markers of vaso-occlusive crisis in sickle SAD mice. Clin Hemorheol Microcirc 2013, 54:297-312.
    • (2013) Clin Hemorheol Microcirc , vol.54 , pp. 297-312
    • Aufradet, E.1    DeSouza, G.2    Bourgeaux, V.3
  • 41
    • 84856255925 scopus 로고    scopus 로고
    • Mouse models for studying pain in sickle disease: effects of strain, age, and acuteness
    • Cain D.M., Vang D., Simone D.A., et al. Mouse models for studying pain in sickle disease: effects of strain, age, and acuteness. Br J Haematol 2012, 156:535-544.
    • (2012) Br J Haematol , vol.156 , pp. 535-544
    • Cain, D.M.1    Vang, D.2    Simone, D.A.3
  • 42
    • 84887331111 scopus 로고    scopus 로고
    • Mast cell activation contributes to sickle cell pathobiology and pain
    • Vincent L., Vang D., Nguyen J., et al. Mast cell activation contributes to sickle cell pathobiology and pain. Blood 2013, 122(11):1853-1862.
    • (2013) Blood , vol.122 , Issue.11 , pp. 1853-1862
    • Vincent, L.1    Vang, D.2    Nguyen, J.3
  • 43
    • 3242792093 scopus 로고    scopus 로고
    • The endothelial biology of sickle cell disease: inflammation and a chronic vasculopathy
    • Hebbel R.P., Osarogiagbon R., Kaul D. The endothelial biology of sickle cell disease: inflammation and a chronic vasculopathy. Microcirculation 2004, 11:129-151.
    • (2004) Microcirculation , vol.11 , pp. 129-151
    • Hebbel, R.P.1    Osarogiagbon, R.2    Kaul, D.3
  • 44
    • 72449211881 scopus 로고    scopus 로고
    • Asystems biology consideration of the vasculopathy of sickle cell anemia: the need for multi-modality chemo-prophylaxis
    • Hebbel R.P., Vercellotti G., Nath K.A. Asystems biology consideration of the vasculopathy of sickle cell anemia: the need for multi-modality chemo-prophylaxis. Cardiovasc Hematol Disord Drug Targets 2009, 9:271-292.
    • (2009) Cardiovasc Hematol Disord Drug Targets , vol.9 , pp. 271-292
    • Hebbel, R.P.1    Vercellotti, G.2    Nath, K.A.3
  • 45
    • 0026463664 scopus 로고
    • Subclinical ischaemic episodes during the steady state of sickle cell anaemia
    • Akinola N.O., Stevens S.M., Franklin I.M., et al. Subclinical ischaemic episodes during the steady state of sickle cell anaemia. JClin Pathol 1992, 45:902-906.
    • (1992) JClin Pathol , vol.45 , pp. 902-906
    • Akinola, N.O.1    Stevens, S.M.2    Franklin, I.M.3
  • 46
    • 0027483349 scopus 로고
    • Is there an acute-phase response in steady-state sickle cell disease?
    • Singhal A., Doherty J.F., Raynes J.G., et al. Is there an acute-phase response in steady-state sickle cell disease?. Lancet 1993, 341:651-653.
    • (1993) Lancet , vol.341 , pp. 651-653
    • Singhal, A.1    Doherty, J.F.2    Raynes, J.G.3
  • 47
    • 0028347684 scopus 로고
    • Monitoring the acute phase response to vaso-occlusive crisis in sickle cell disease
    • Stuart J., Stone P.C., Akinola N.O., et al. Monitoring the acute phase response to vaso-occlusive crisis in sickle cell disease. JClin Pathol 1994, 47:166-169.
    • (1994) JClin Pathol , vol.47 , pp. 166-169
    • Stuart, J.1    Stone, P.C.2    Akinola, N.O.3
  • 48
    • 8644241558 scopus 로고    scopus 로고
    • The not-so-simple process of sickle cell vasoocclusion
    • Embury S.H. The not-so-simple process of sickle cell vasoocclusion. Microcirculation 2004, 11:101-113.
    • (2004) Microcirculation , vol.11 , pp. 101-113
    • Embury, S.H.1
  • 49
    • 0036908599 scopus 로고    scopus 로고
    • Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease
    • Reiter C.D., Wang X., Tanus-Santos J.E., et al. Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease. Nat Med 2002, 8:1383-1389.
    • (2002) Nat Med , vol.8 , pp. 1383-1389
    • Reiter, C.D.1    Wang, X.2    Tanus-Santos, J.E.3
  • 50
    • 34547120742 scopus 로고    scopus 로고
    • Characterization of heme as activator of Toll-like receptor 4
    • Figueiredo R.T., Fernandez P.L., Mourao-Sa D.S., et al. Characterization of heme as activator of Toll-like receptor 4. JBiol Chem 2007, 282:20221-20229.
    • (2007) JBiol Chem , vol.282 , pp. 20221-20229
    • Figueiredo, R.T.1    Fernandez, P.L.2    Mourao-Sa, D.S.3
  • 51
    • 84882741604 scopus 로고    scopus 로고
    • Epo and non-hematopoietic cells: what do we know?
    • Ogunshola O.O., Bogdanova A.Y. Epo and non-hematopoietic cells: what do we know?. Methods Mol Biol 2013, 982:13-41.
    • (2013) Methods Mol Biol , vol.982 , pp. 13-41
    • Ogunshola, O.O.1    Bogdanova, A.Y.2
  • 52
    • 0043156081 scopus 로고    scopus 로고
    • Mechanism of monocyte activation and expression of proinflammatory cytochemokines by placenta growth factor
    • Selvaraj S.K., Giri R.K., Perelman N., et al. Mechanism of monocyte activation and expression of proinflammatory cytochemokines by placenta growth factor. Blood 2003, 102:1515-1524.
    • (2003) Blood , vol.102 , pp. 1515-1524
    • Selvaraj, S.K.1    Giri, R.K.2    Perelman, N.3
  • 53
    • 44649115688 scopus 로고    scopus 로고
    • Functional consequences of toll-like receptor 4 polymorphisms
    • Ferwerda B., McCall M.B., Verheijen K., et al. Functional consequences of toll-like receptor 4 polymorphisms. Mol Med 2008, 14:346-352.
    • (2008) Mol Med , vol.14 , pp. 346-352
    • Ferwerda, B.1    McCall, M.B.2    Verheijen, K.3
  • 54
    • 77955897953 scopus 로고    scopus 로고
    • Duffy antigen receptor for chemokines (Darc) polymorphism regulates circulating concentrations of monocyte chemoattractant protein-1 and other inflammatory mediators
    • Schnabel R.B., Baumert J., Barbalic M., et al. Duffy antigen receptor for chemokines (Darc) polymorphism regulates circulating concentrations of monocyte chemoattractant protein-1 and other inflammatory mediators. Blood 2010, 115:5289-5299.
    • (2010) Blood , vol.115 , pp. 5289-5299
    • Schnabel, R.B.1    Baumert, J.2    Barbalic, M.3
  • 55
    • 84860561123 scopus 로고    scopus 로고
    • The association between a Darc gene polymorphism and clinical outcomes in African American patients with acute lung injury
    • Kangelaris K.N., Sapru A., Calfee C.S., et al. The association between a Darc gene polymorphism and clinical outcomes in African American patients with acute lung injury. Chest 2012, 141:1160-1169.
    • (2012) Chest , vol.141 , pp. 1160-1169
    • Kangelaris, K.N.1    Sapru, A.2    Calfee, C.S.3
  • 56
    • 0030024151 scopus 로고    scopus 로고
    • Passive smoking and impaired endothelium-dependent arterial dilatation in healthy young adults
    • Celermajer D.S., Adams M.R., Clarkson P., et al. Passive smoking and impaired endothelium-dependent arterial dilatation in healthy young adults. NEngl J Med 1996, 334:150-154.
    • (1996) NEngl J Med , vol.334 , pp. 150-154
    • Celermajer, D.S.1    Adams, M.R.2    Clarkson, P.3
  • 57
    • 84860524435 scopus 로고    scopus 로고
    • Carbon monoxide in acute lung injury
    • Faller S., Hoetzel A. Carbon monoxide in acute lung injury. Curr Pharm Biotechnol 2012, 13:777-786.
    • (2012) Curr Pharm Biotechnol , vol.13 , pp. 777-786
    • Faller, S.1    Hoetzel, A.2
  • 58
    • 0035869387 scopus 로고    scopus 로고
    • Endothelial dysfunction in patients with sickle cell disease is related to selective impairment of shear stress-mediated vasodilation
    • Belhassen L., Pelle G., Sediame S., et al. Endothelial dysfunction in patients with sickle cell disease is related to selective impairment of shear stress-mediated vasodilation. Blood 2001, 97:1584-1589.
    • (2001) Blood , vol.97 , pp. 1584-1589
    • Belhassen, L.1    Pelle, G.2    Sediame, S.3
  • 59
    • 0037458069 scopus 로고    scopus 로고
    • Divergent nitric oxide bioavailability in men and women with sickle cell disease
    • Gladwin M.T., Schechter A.N., Ognibene F.P., et al. Divergent nitric oxide bioavailability in men and women with sickle cell disease. Circulation 2003, 107:271-278.
    • (2003) Circulation , vol.107 , pp. 271-278
    • Gladwin, M.T.1    Schechter, A.N.2    Ognibene, F.P.3
  • 60
    • 78851468762 scopus 로고    scopus 로고
    • Reconstructing sickle cell disease: a data-based analysis of the "hyperhemolysis paradigm" for pulmonary hypertension from the perspective of evidence-based medicine
    • Hebbel R.P. Reconstructing sickle cell disease: a data-based analysis of the "hyperhemolysis paradigm" for pulmonary hypertension from the perspective of evidence-based medicine. Am J Hematol 2011, 86:123-154.
    • (2011) Am J Hematol , vol.86 , pp. 123-154
    • Hebbel, R.P.1
  • 61
    • 0034702282 scopus 로고    scopus 로고
    • Causes and outcomes of the acute chest syndrome in sickle cell disease. National Acute Chest Syndrome Study Group
    • Vichinsky E.P., Neumayr L.D., Earles A.N., et al. Causes and outcomes of the acute chest syndrome in sickle cell disease. National Acute Chest Syndrome Study Group. NEngl J Med 2000, 342:1855-1865.
    • (2000) NEngl J Med , vol.342 , pp. 1855-1865
    • Vichinsky, E.P.1    Neumayr, L.D.2    Earles, A.N.3
  • 62
    • 33747479576 scopus 로고    scopus 로고
    • Asthma is associated with acute chest syndrome and pain in children with sickle cell anemia
    • Boyd J.H., Macklin E.A., Strunk R.C., et al. Asthma is associated with acute chest syndrome and pain in children with sickle cell anemia. Blood 2006, 108:2923-2927.
    • (2006) Blood , vol.108 , pp. 2923-2927
    • Boyd, J.H.1    Macklin, E.A.2    Strunk, R.C.3
  • 63
    • 77952556114 scopus 로고    scopus 로고
    • Smoking is associated with an increased risk of acute chest syndrome and pain among adults with sickle cell disease
    • Cohen R.T., DeBaun M.R., Blinder M.A., et al. Smoking is associated with an increased risk of acute chest syndrome and pain among adults with sickle cell disease. Blood 2010, 115:3852-3854.
    • (2010) Blood , vol.115 , pp. 3852-3854
    • Cohen, R.T.1    DeBaun, M.R.2    Blinder, M.A.3
  • 64
    • 0023924297 scopus 로고
    • Platelet-activating factor primes neutrophil responses to agonists: role in promoting neutrophil-mediated endothelial damage
    • Vercellotti G.M., Yin H.Q., Gustafson K.S., et al. Platelet-activating factor primes neutrophil responses to agonists: role in promoting neutrophil-mediated endothelial damage. Blood 1988, 71:1100-1107.
    • (1988) Blood , vol.71 , pp. 1100-1107
    • Vercellotti, G.M.1    Yin, H.Q.2    Gustafson, K.S.3
  • 65
    • 0028567275 scopus 로고
    • The postischemic gut serves as a priming bed for circulating neutrophils that provoke multiple organ failure
    • Moore E.E., Moore F.A., Franciose R.J., et al. The postischemic gut serves as a priming bed for circulating neutrophils that provoke multiple organ failure. JTrauma 1994, 37:881-887.
    • (1994) JTrauma , vol.37 , pp. 881-887
    • Moore, E.E.1    Moore, F.A.2    Franciose, R.J.3
  • 66
    • 33745528048 scopus 로고    scopus 로고
    • Secretory phospholipase A2 levels in patients with sickle cell disease and acute chest syndrome
    • Ballas S.K., Files B., Luchtman-Jones L., et al. Secretory phospholipase A2 levels in patients with sickle cell disease and acute chest syndrome. Hemoglobin 2006, 30:165-170.
    • (2006) Hemoglobin , vol.30 , pp. 165-170
    • Ballas, S.K.1    Files, B.2    Luchtman-Jones, L.3
  • 67
    • 80052367667 scopus 로고    scopus 로고
    • Ethnic variability in persistent asthma after in utero tobacco exposure
    • Akuete K., Oh S.S., Thyne S., et al. Ethnic variability in persistent asthma after in utero tobacco exposure. Pediatrics 2011, 128:e623-e630.
    • (2011) Pediatrics , vol.128
    • Akuete, K.1    Oh, S.S.2    Thyne, S.3
  • 68
    • 79957852121 scopus 로고    scopus 로고
    • Elevation of IgE in children with sickle cell disease is associated with doctor diagnosis of asthma and increased morbidity
    • An P., Barron-Casella E.A., Strunk R.C., et al. Elevation of IgE in children with sickle cell disease is associated with doctor diagnosis of asthma and increased morbidity. JAllergy Clin Immunol 2011, 127:1440-1446.
    • (2011) JAllergy Clin Immunol , vol.127 , pp. 1440-1446
    • An, P.1    Barron-Casella, E.A.2    Strunk, R.C.3
  • 69
    • 84874206492 scopus 로고    scopus 로고
    • Cytokinergic IgE action in mast cell activation
    • Bax H.J., Keeble A.H., Gould H.J. Cytokinergic IgE action in mast cell activation. Front Immunol 2012, 3:229.
    • (2012) Front Immunol , vol.3 , pp. 229
    • Bax, H.J.1    Keeble, A.H.2    Gould, H.J.3
  • 70
    • 84873589349 scopus 로고    scopus 로고
    • TLR signaling in mast cells: common and unique features
    • Sandig H., Bulfone-Paus S. TLR signaling in mast cells: common and unique features. Front Immunol 2012, 3:185.
    • (2012) Front Immunol , vol.3 , pp. 185
    • Sandig, H.1    Bulfone-Paus, S.2
  • 71
    • 84880555809 scopus 로고    scopus 로고
    • The role of TLR4 in the pathogenesis of indirect acute lung injury
    • Hu R., Xu H., Jiang H., et al. The role of TLR4 in the pathogenesis of indirect acute lung injury. Front Biosci (Landmark Ed) 2013, 18:1244-1255.
    • (2013) Front Biosci (Landmark Ed) , vol.18 , pp. 1244-1255
    • Hu, R.1    Xu, H.2    Jiang, H.3
  • 72
    • 1542511749 scopus 로고    scopus 로고
    • Enhanced pulmonary and systemic response to endotoxin in transgenic sickle mice
    • Holtzclaw J.D., Jack D., Aguayo S.M., et al. Enhanced pulmonary and systemic response to endotoxin in transgenic sickle mice. Am J Respir Crit Care Med 2004, 169:687-695.
    • (2004) Am J Respir Crit Care Med , vol.169 , pp. 687-695
    • Holtzclaw, J.D.1    Jack, D.2    Aguayo, S.M.3
  • 73
    • 0033152361 scopus 로고    scopus 로고
    • Sickle cell anemia as a possible state of enhanced anti-apoptotic tone: survival effect of vascular endothelial growth factor on circulating and unanchored endothelial cells
    • Solovey A., Gui L., Ramakrishnan S., et al. Sickle cell anemia as a possible state of enhanced anti-apoptotic tone: survival effect of vascular endothelial growth factor on circulating and unanchored endothelial cells. Blood 1999, 93:3824-3830.
    • (1999) Blood , vol.93 , pp. 3824-3830
    • Solovey, A.1    Gui, L.2    Ramakrishnan, S.3
  • 74
    • 78651111054 scopus 로고    scopus 로고
    • Differential endothelial cell gene expression by African Americans versus Caucasian Americans: a possible contribution to health disparity in vascular disease and cancer
    • Wei P., Milbauer L.C., Enenstein J., et al. Differential endothelial cell gene expression by African Americans versus Caucasian Americans: a possible contribution to health disparity in vascular disease and cancer. BMC Med 2011, 9:2.
    • (2011) BMC Med , vol.9 , pp. 2
    • Wei, P.1    Milbauer, L.C.2    Enenstein, J.3
  • 75
    • 84868582399 scopus 로고    scopus 로고
    • Sickle cell pain: a critical reappraisal
    • Ballas S.K., Gupta K., Adams-Graves P. Sickle cell pain: a critical reappraisal. Blood 2012, 120:3647-3656.
    • (2012) Blood , vol.120 , pp. 3647-3656
    • Ballas, S.K.1    Gupta, K.2    Adams-Graves, P.3
  • 76
    • 78649740275 scopus 로고    scopus 로고
    • Adenosine A2A receptors induced on iNKT and NK cells reduce pulmonary inflammation and injury in mice with sickle cell disease
    • Wallace K.L., Linden J. Adenosine A2A receptors induced on iNKT and NK cells reduce pulmonary inflammation and injury in mice with sickle cell disease. Blood 2010, 116:5010-5020.
    • (2010) Blood , vol.116 , pp. 5010-5020
    • Wallace, K.L.1    Linden, J.2
  • 77
    • 81155162494 scopus 로고    scopus 로고
    • Immunopathogenesis of ischemia/reperfusion-associated tissue damage
    • Ioannou A., Dalle Lucca J., Tsokos G.C. Immunopathogenesis of ischemia/reperfusion-associated tissue damage. Clin Immunol 2011, 141:3-14.
    • (2011) Clin Immunol , vol.141 , pp. 3-14
    • Ioannou, A.1    Dalle Lucca, J.2    Tsokos, G.C.3
  • 78
    • 84888260688 scopus 로고    scopus 로고
    • MP4CO, a pegylated hemoglobin saturated with carbon monoxide is a modulator of HO-1, inflammation and vaso-occlusion in transgenic sickle mice
    • Belcher J.D., Young M., Chen C., et al. MP4CO, a pegylated hemoglobin saturated with carbon monoxide is a modulator of HO-1, inflammation and vaso-occlusion in transgenic sickle mice. Blood 2013, 122(15):2757-2764.
    • (2013) Blood , vol.122 , Issue.15 , pp. 2757-2764
    • Belcher, J.D.1    Young, M.2    Chen, C.3
  • 79
    • 3042621306 scopus 로고    scopus 로고
    • Anti-inflammatory therapy ameliorates leukocyte adhesion and microvascular flow abnormalities in transgenic sickle mice
    • Kaul D.K., Liu X.D., Choong S., et al. Anti-inflammatory therapy ameliorates leukocyte adhesion and microvascular flow abnormalities in transgenic sickle mice. Am J Physiol Heart Circ Physiol 2004, 287:H293-H301.
    • (2004) Am J Physiol Heart Circ Physiol , vol.287
    • Kaul, D.K.1    Liu, X.D.2    Choong, S.3
  • 80
    • 21044448516 scopus 로고    scopus 로고
    • Polynitroxyl albumin inhibits inflammation and vasoocclusion in transgenic sickle mice
    • Mahaseth H., Vercellotti G.M., Welch T.E., et al. Polynitroxyl albumin inhibits inflammation and vasoocclusion in transgenic sickle mice. JLab Clin Med 2005, 145:204-211.
    • (2005) JLab Clin Med , vol.145 , pp. 204-211
    • Mahaseth, H.1    Vercellotti, G.M.2    Welch, T.E.3
  • 81
    • 33745712683 scopus 로고    scopus 로고
    • Inhibition of sickle red cell adhesion and vasoocclusion in the microcirculation by antioxidants
    • Kaul D.K., Liu X.D., Zhang X., et al. Inhibition of sickle red cell adhesion and vasoocclusion in the microcirculation by antioxidants. Am J Physiol Heart Circ Physiol 2006, 291:H167-H175.
    • (2006) Am J Physiol Heart Circ Physiol , vol.291
    • Kaul, D.K.1    Liu, X.D.2    Zhang, X.3
  • 82
    • 33748329451 scopus 로고    scopus 로고
    • Robust vascular protective effect of hydroxamic acid derivatives in a sickle mouse model of inflammation
    • Kaul D.K., Kollander R., Mahaseth H., et al. Robust vascular protective effect of hydroxamic acid derivatives in a sickle mouse model of inflammation. Microcirculation 2006, 13:489-497.
    • (2006) Microcirculation , vol.13 , pp. 489-497
    • Kaul, D.K.1    Kollander, R.2    Mahaseth, H.3
  • 83
    • 77950549033 scopus 로고    scopus 로고
    • The HDAC inhibitors trichostatin A and suberoylanilide hydroxamic acid exhibit multiple modalities of benefit for the vascular pathobiology of sickle transgenic mice
    • Hebbel R.P., Vercellotti G.M., Pace B.S., et al. The HDAC inhibitors trichostatin A and suberoylanilide hydroxamic acid exhibit multiple modalities of benefit for the vascular pathobiology of sickle transgenic mice. Blood 2010, 115:2483-2490.
    • (2010) Blood , vol.115 , pp. 2483-2490
    • Hebbel, R.P.1    Vercellotti, G.M.2    Pace, B.S.3
  • 84
    • 77949448669 scopus 로고    scopus 로고
    • Nuclear factor-kappa B (NFkappaB) component p50 in blood mononuclear cells regulates endothelial tissue factor expression in sickle transgenic mice: implications for the coagulopathy of sickle cell disease
    • Kollander R., Solovey A., Milbauer L.C., et al. Nuclear factor-kappa B (NFkappaB) component p50 in blood mononuclear cells regulates endothelial tissue factor expression in sickle transgenic mice: implications for the coagulopathy of sickle cell disease. Transl Res 2010, 155:170-177.
    • (2010) Transl Res , vol.155 , pp. 170-177
    • Kollander, R.1    Solovey, A.2    Milbauer, L.C.3
  • 85
    • 77954541322 scopus 로고    scopus 로고
    • Heme oxygenase-1 gene delivery by Sleeping Beauty inhibits vascular stasis in a murine model of sickle cell disease
    • Belcher J.D., Vineyard J.V., Bruzzone C.M., et al. Heme oxygenase-1 gene delivery by Sleeping Beauty inhibits vascular stasis in a murine model of sickle cell disease. JMol Med (Berl) 2010, 88:665-675.
    • (2010) JMol Med (Berl) , vol.88 , pp. 665-675
    • Belcher, J.D.1    Vineyard, J.V.2    Bruzzone, C.M.3
  • 86
    • 84874424153 scopus 로고    scopus 로고
    • Plasma hemoglobin and heme trigger Weibel Palade body exocytosis and vaso-occlusion in transgenic sickle mice
    • [abstract]
    • Belcher J., Nguyen J., Chen C., et al. Plasma hemoglobin and heme trigger Weibel Palade body exocytosis and vaso-occlusion in transgenic sickle mice. Blood 2011, 118:896. [abstract].
    • (2011) Blood , vol.118 , pp. 896
    • Belcher, J.1    Nguyen, J.2    Chen, C.3
  • 87
    • 0023180456 scopus 로고
    • Pluronic F-68 reduces the endothelial adherence and improves the rheology of liganded sickle erythrocytes
    • Smith C.M., Hebbel R.P., Tukey D.P., et al. Pluronic F-68 reduces the endothelial adherence and improves the rheology of liganded sickle erythrocytes. Blood 1987, 69:1631-1636.
    • (1987) Blood , vol.69 , pp. 1631-1636
    • Smith, C.M.1    Hebbel, R.P.2    Tukey, D.P.3
  • 88
    • 74049088214 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase and nitric oxide regulate endothelial tissue factor expression invivo in the sickle transgenic mouse
    • Solovey A., Kollander R., Milbauer L.C., et al. Endothelial nitric oxide synthase and nitric oxide regulate endothelial tissue factor expression invivo in the sickle transgenic mouse. Am J Hematol 2010, 85:41-45.
    • (2010) Am J Hematol , vol.85 , pp. 41-45
    • Solovey, A.1    Kollander, R.2    Milbauer, L.C.3
  • 89
    • 84896829319 scopus 로고    scopus 로고
    • Interference with TNF-alpha using long-term Etanercept in S+SAntilles sickle transgenic mice ameliorates abnormal endothelial activation, vasoocclusion, and pulmonary hypertension including its pulmonary aterial wall remodeling
    • [Abstract]
    • Solovey A., Somani A., Chen C., et al. Interference with TNF-alpha using long-term Etanercept in S+SAntilles sickle transgenic mice ameliorates abnormal endothelial activation, vasoocclusion, and pulmonary hypertension including its pulmonary aterial wall remodeling. Blood 2013, 122:728. [Abstract].
    • (2013) Blood , vol.122 , pp. 728
    • Solovey, A.1    Somani, A.2    Chen, C.3
  • 90
    • 12144291636 scopus 로고    scopus 로고
    • Hypoxia-induced acute lung injury in murine models of sickle cell disease
    • Pritchard K.A., Ou J., Ou Z., et al. Hypoxia-induced acute lung injury in murine models of sickle cell disease. Am J Physiol Lung Cell Mol Physiol 2004, 286:L705-L714.
    • (2004) Am J Physiol Lung Cell Mol Physiol , vol.286
    • Pritchard, K.A.1    Ou, J.2    Ou, Z.3


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