P-cadherin signals through the laminin receptor α6β4 integrin to induce stem cell and invasive properties to basal-like breast cancer cells

Oncotarget

Volumn 5, Issue 3, 2014, Pages 679-692

  Vieira, André Filipe ^a   Ribeiro, Ana Sofia ^a   Dionísio, Maria Rita ^a,b   Sousa, Bárbara ^a   Nobre, Ana Rita ^a   Albergaria, André ^a   Santiago Gómez, Angélica ^c   Mendes, Nuno ^a   Gerhard, Renê ^a   Schmitt, Fernando ^a,d   Clarke, Robert B ^c   Paredes, Joana ^a,d  

^a UNIVERSITY OF PORTO   (Portugal)

^b Gulbenkian Program for Advanced Medical Education   (Portugal)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

^d University of Porto   (Portugal)

Author keywords

Breast cancer; Cancer stem cells; FAK; Invasion; P cadherin; Src; 6 4 integrin

Indexed keywords

ALPHA6BETA4 INTEGRIN; FOCAL ADHESION KINASE; INTEGRIN; LAMININ; LAMININ RECEPTOR; P CADHERIN; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; CADHERIN;

ARTICLE; BASAL LIKE BREAST CANCER; BASEMENT MEMBRANE; CANCER GROWTH; CANCER PROGNOSIS; CANCER STEM CELL; CELL ADHESION; DOWNSTREAM PROCESSING; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; IN VIVO STUDY; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; TUMOR XENOGRAFT; ANIMAL; BREAST TUMOR; FEMALE; GENETICS; MCF 7 CELL LINE; METABOLISM; MOUSE; NUDE MOUSE; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE; TUMOR INVASION; UPREGULATION; XENOGRAFT;

ANIMALS; BREAST NEOPLASMS; CADHERINS; CELL ADHESION; CELL LINE, TUMOR; FEMALE; HETEROGRAFTS; HUMANS; INTEGRIN ALPHA6BETA4; MCF-7 CELLS; MICE; MICE, NUDE; NEOPLASM INVASIVENESS; NEOPLASTIC STEM CELLS; PHOSPHORYLATION; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84896821980     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.1459     Document Type: Article

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