Induction of Gsk3β-β-TrCP interaction is required for late phase stabilization of β-catenin in canonical wnt signaling

Journal of Biological Chemistry

Volumn 289, Issue 10, 2014, Pages 7099-7108

  Gao, Chenxi ^a   Chen, Guangming ^a   Romero, Guillermo ^a   Moschos, Stergios ^a,b   Xu, Xiang ^a   Hu, Jing ^a  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

STABILIZATION;

CANONICAL WNT SIGNALING; PHASE STABILIZATION; WNT PATHWAY; WNT SIGNALING;

SIGNALING;

BETA CATENIN; BETA TRANSDUCIN REPEAT CONTAINING PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; WNT PROTEIN;

ARTICLE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN TARGETING; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; UBIQUITINATION;

BETA-CATENIN; GLYCOGEN SYNTHASE KINASE 3; UBIQUITIN LIGASE; UBIQUITINATION; WNT SIGNALING;

AMINO ACID SEQUENCE; ANIMALS; BETA CATENIN; BETA-TRANSDUCIN REPEAT-CONTAINING PROTEINS; CELL LINE, TUMOR; ENZYME STABILITY; GENE KNOCKDOWN TECHNIQUES; GLYCOGEN SYNTHASE KINASE 3; HEK293 CELLS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION; WNT SIGNALING PATHWAY;

EID: 84896798019     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.532606     Document Type: Article

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