The metabolic origins of mannose in glycoproteins

Journal of Biological Chemistry

Volumn 289, Issue 10, 2014, Pages 6751-6761

  Ichikawa, Mie ^a   Scott, David A ^a   Losfeld, Marie Estelle ^a   Freeze, Hudson H ^a  

^a BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLYCOPROTEINS; POLYSACCHARIDES;

GLUCONEOGENESIS; N-GLYCAN; N-GLYCANS;

METABOLISM;

CARBON 13; GLUCOSE; GLYCAN; GLYCOGEN; GLYCOPROTEIN; MANNOSE; MANNOSE PHOSPHATE ISOMERASE;

ANIMAL CELL; ARTICLE; CARBOHYDRATE ANALYSIS; CARBOHYDRATE SYNTHESIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; FIBROBLAST; GLUCONEOGENESIS; GLUCOSE TRANSPORT; GLYCOSYLATION; HUMAN; HUMAN CELL; MASS FRAGMENTOGRAPHY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; QUANTITATIVE ANALYSIS; SENSITIVITY ANALYSIS;

GC-MS; GENETIC DISEASES; GLUCOSE METABOLISM; GLYCOCONJUGATE; METABOLIC TRACERS;

CELLS, CULTURED; FIBROBLASTS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GLUCONEOGENESIS; GLUCOSE; GLYCOGEN; GLYCOPROTEINS; GLYCOSYLATION; HUMANS; MANNOSE; PROTEOLYSIS;

EID: 84896784459     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.544064     Document Type: Article

References (26)

1. Sharma, V., Ichikawa, M., He, P., Scott, D. A., Bravo, Y., Dahl, R., Ng, B. G., Cosford, N. D., and Freeze, H. H. (2011) Phosphomannose isomerase inhibitors improve N-glycosylation in selected phosphomannomutase-deficient fibroblasts. J. Biol. Chem. 286, 39431-39438
2. Panneerselvam, K., and Freeze, H. H. (1996) Mannose corrects altered N-glycosylation in carbohydrate-deficient glycoprotein syndrome fibroblasts. J. Clin. Invest. 97, 1478-1487
3. Schneider, A., Thiel, C., Rindermann, J., DeRossi, C., Popovici, D., Hoffmann, G. F., Gröne, H. J., and Körner, C. (2012) Successful prenatal mannose treatment for congenital disorder of glycosylation-Ia in mice. Nat. Med. 18, 71-73
4. Niehues, R., Hasilik, M., Alton, G., Körner, C., Schiebe-Sukumar, M., Koch, H. G., Zimmer, K. P., Wu, R., Harms, E., Reiter, K., von Figura, K., Freeze, H. H., Harms, H. K., and Marquardt, T. (1998) Carbohydratedeficient glycoprotein syndrome type Ib. Phosphomannose isomerase deficiency and mannose therapy. J. Clin. Invest. 101, 1414-1420
5. Harms, H. K., Zimmer, K. P., Kurnik, K., Bertele-Harms, R. M., Weidinger, S., and Reiter, K. (2002) Oral mannose therapy persistently corrects the severe clinical symptoms and biochemical abnormalities of phosphomannose isomerase deficiency. Acta Paediatr. 91, 1065-1072
6. Kjaergaard, S., Kristiansson, B., Stibler, H., Freeze, H. H., Schwartz, M., Martinsson, T., and Skovby, F. (1998) Failure of short-term mannose therapy of patients with carbohydrate-deficient glycoprotein syndrome type 1A. Acta Paediatr. 87, 884-888
7. Mayatepek, E., and Kohlmüller, D. (1998) Mannose supplementation in carbohydrate-deficient glycoprotein syndrome type I and phosphomannomutase deficiency. Eur. J. Pediatr. 157, 605-606
8. Nakajima, K., Ito, E., Ohtsubo, K., Shirato, K., Takamiya, R., Kitazume, S., Angata, T., and Taniguchi, N. (2013) Mass isotopomer analysis of metabolically labeled nucleotide sugars and N-and O-glycans for tracing nucleotide sugar metabolisms. Mol. Cell. Proteomics 12, 2468-2480
9. Sharma, V., and Freeze, H. H. (2011) Mannose efflux from the cells: a potential source of mannose in blood. J. Biol. Chem. 286, 10193-10200
10. Passonneau, J. V., and Lauderdale, V. R. (1974) A comparison of three methods of glycogen measurement in tissues. Anal. Biochem. 60, 405-412
11. Price, N. P. (2004) Acylic sugar derivatives forGC/MSanalysis of 13C-enrichment during carbohydrate metabolism. Anal. Chem. 76, 6566-6574
12. Scott, D. A., Richardson, A. D., Filipp, F. V., Knutzen, C. A., Chiang, G. G., Ronai, Z. A., Osterman, A. L., and Smith, J. W. (2011) Comparative metabolic flux profiling of melanoma cell lines: beyond the Warburg effect. J. Biol. Chem. 286, 42626-42634
13. Nanchen, A., Fuhrer, T., and Sauer, U. (2007) Determination of metabolic flux ratios from 13C-experiments and gas chromatography-mass spectrometry data: protocol and principles. Methods Mol. Biol. 358, 177-197
14. van Winden, W. A., Wittmann, C., Heinzle, E., and Heijnen, J. J. (2002) Correcting mass isotopomer distributions for naturally occurring isotopes. Biotechnol. Bioeng. 80, 477-479
15. Portnoy, V. A., Scott, D. A., Lewis, N. E., Tarasova, Y., Osterman, A. L., and Palsson, B. Ø. (2010) Deletion of genes encoding cytochrome oxidases and quinol monooxygenase blocks the aerobic-anaerobic shift in Escherichia coli K-12 MG1655. Appl. Environ. Microbiol. 76, 6529-6540
16. Sickmann, H. M., Schousboe, A., Fosgerau, K., and Waagepetersen, H. S. (2005) Compartmentation of lactate originating from glycogen and glucose in cultured astrocytes. Neurochem. Res. 30, 1295-1304
17. Halket, J. M., and Zaikin, V. G. (2003) Derivatization in mass spectrometry-1. Silylation. Eur. J. Mass Spectrom. (Chichester, Eng.) 9, 1-21
18. Lehrman, M. A. (2006) Stimulation of N-linked glycosylation and lipidlinked oligosaccharide synthesis by stress responses in metazoan cells. Crit. Rev. Biochem. Mol. Biol. 41, 51-75
19. Shang, J., and Lehrman, M. A. (2004) Activation of glycogen phosphorylase with 5-aminoimidazole-4-carboxamide riboside (AICAR). Assessment of glycogen as a precursor of mannosyl residues in glycoconjugates. J. Biol. Chem. 279, 12076-12080
20. Moore, S. E., Bauvy, C., and Codogno, P. (1995) Endoplasmic reticulumto-cytosol transport of free polymannose oligosaccharides in permeabilized HepG2 cells. EMBO J. 14, 6034-6042
21. Gill, A., Gao, N., and Lehrman, M. A. (2002) Rapid activation of glycogen phosphorylase by the endoplasmic reticulum unfolded protein response. J. Biol. Chem. 277, 44747-44753
22. McMahon, R. J., and Frost, S. C. (1996) Glycogen: a carbohydrate source for GLUT-1 glycosylation during glucose deprivation of 3T3-L1 adipocytes. Am. J. Physiol. 270, E640-645
23. Panneerselvam, K., Etchison, J. R., and Freeze, H. H. (1997) Human fibroblasts prefer mannose over glucose as a source of mannose for N-glycosylation: evidence for the functional importance of transported mannose. J. Biol. Chem. 272, 23123-23129
24. Grempler, R., Augustin, R., Froehner, S., Hildebrandt, T., Simon, E., Mark, M., and Eickelmann, P. (2012) Functional characterisation of human SGLT-5 as a novel kidney-specific sodium-dependent sugar transporter. FEBS Lett. 586, 248-253
25. Malaisse, W. J., Zhang, Y., and Sener, A. (2004) Enzyme-to-enzyme channeling in the early steps of glycolysis in rat pancreatic islets. Endocrine 24, 105-109
26. Rose, I. A., O'Connell, E. L., and Schray, K. J. (1973) Mannose 6-phosphate: anomeric form used by phosphomannose isomerase and its 1-epimerization by phosphoglucose isomerase. J. Biol. Chem. 248, 2232-2234