-
1
-
-
84872967522
-
Cancer statistics, 2013
-
Siegel, R., Naishadham, D. & Jemal, A. Cancer statistics, 2013. CA: A Cancer Journal for Clinicians 63, 11-30 (2013).
-
(2013)
CA: A Cancer Journal for Clinicians
, vol.63
, pp. 11-30
-
-
Siegel, R.1
Naishadham, D.2
Jemal, A.3
-
3
-
-
0028113345
-
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
-
Miki, Y. et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 266, 66-71 (1994).
-
(1994)
Science
, vol.266
, pp. 66-71
-
-
Miki, Y.1
-
4
-
-
0006713602
-
Identification of the breast cancer susceptibility gene BRCA2
-
Wooster, R. et al. Identification of the breast cancer susceptibility gene BRCA2. Nature 378, 789-792 (1995).
-
(1995)
Nature
, vol.378
, pp. 789-792
-
-
Wooster, R.1
-
5
-
-
0029585997
-
Life-time risk of different cancers in hereditary non-polyposis colorectal cancer (HNPCC) syndrome
-
Aarnio, M., Mecklin, J. P., Aaltonen, L. A., Nystrom-Lahti, M. & Jarvinen, H. J. Life-time risk of different cancers in hereditary non-polyposis colorectal cancer (HNPCC) syndrome. Int J Cancer. 64, 430-433 (1995).
-
(1995)
Int J Cancer
, vol.64
, pp. 430-433
-
-
Aarnio, M.1
Mecklin, J.P.2
Aaltonen, L.A.3
Nystrom-Lahti, M.4
Jarvinen, H.J.5
-
6
-
-
77951720395
-
Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene
-
Meindl, A. et al. Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene. Nat Genet. 42, 410-414 (2010).
-
(2010)
Nat Genet
, vol.42
, pp. 410-414
-
-
Meindl, A.1
-
7
-
-
79960330300
-
Hereditary breast and ovarian cancer: New genes, new treatments, new concepts
-
Meindl, A., Ditsch, N., Kast, K., Rhiem, K. & Schmutzler, R. K. Hereditary breast and ovarian cancer: new genes, new treatments, new concepts. Dtsch Arztebl Int. 108, 323-330 (2011).
-
(2011)
Dtsch Arztebl Int
, vol.108
, pp. 323-330
-
-
Meindl, A.1
Ditsch, N.2
Kast, K.3
Rhiem, K.4
Schmutzler, R.K.5
-
8
-
-
80052264429
-
Germline mutations in RAD51D confer susceptibility to ovarian cancer
-
Loveday, C. et al. Germline mutations in RAD51D confer susceptibility to ovarian cancer. Nat Genet. 43, 879-882 (2011).
-
(2011)
Nat Genet
, vol.43
, pp. 879-882
-
-
Loveday, C.1
-
9
-
-
84875717832
-
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
-
Bojesen, S. E. et al.Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nat Genet. 45, 371-384 (2013).
-
(2013)
Nat Genet
, vol.45
, pp. 371-384
-
-
Bojesen, S.E.1
-
10
-
-
84875908264
-
Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31
-
Permuth-Wey, J. et al. Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31. Nat Commun. 4, 1627 (2013).
-
(2013)
Nat Commun.
, vol.4
, pp. 1627
-
-
Permuth-Wey, J.1
-
11
-
-
84875707717
-
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer
-
Pharoah, P. D. et al. GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. Nat Genet. 45, 362-370 (2013).
-
(2013)
Nat Genet
, vol.45
, pp. 362-370
-
-
Pharoah, P.D.1
-
12
-
-
84875904387
-
Epigenetic analysis leads to identification of HNF1B as a subtypespecific susceptibility gene for ovarian cancer
-
Shen, H. et al. Epigenetic analysis leads to identification of HNF1B as a subtypespecific susceptibility gene for ovarian cancer. Nat Commun. 4, 1628 (2013).
-
(2013)
Nat Commun.
, vol.4
, pp. 1628
-
-
Shen, H.1
-
13
-
-
77957584092
-
Common variants at 19p13 are associated with susceptibility to ovarian cancer
-
Bolton, K. L. et al. Common variants at 19p13 are associated with susceptibility to ovarian cancer. Nat Genet. 42, 880-884 (2010).
-
(2010)
Nat Genet
, vol.42
, pp. 880-884
-
-
Bolton, K.L.1
-
14
-
-
77957571905
-
A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24
-
Goode, E. L. et al. A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24. Nat Genet. 42, 874-879 (2010).
-
(2010)
Nat Genet.
, vol.42
, pp. 874-879
-
-
Goode, E.L.1
-
15
-
-
69349102630
-
A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2
-
Song, H. et al. A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. Nat Genet. 41, 996-1000 (2009).
-
(2009)
Nat Genet.
, vol.41
, pp. 996-1000
-
-
Song, H.1
-
16
-
-
63549126247
-
The contribution of BRCA1 and BRCA2 to ovarian cancer
-
Ramus, S. J. & Gayther, S. A. The contribution of BRCA1 and BRCA2 to ovarian cancer. Mol Oncol. 3, 138-150 (2009).
-
(2009)
Mol Oncol
, vol.3
, pp. 138-150
-
-
Ramus, S.J.1
Gayther, S.A.2
-
17
-
-
0031755914
-
Frequency of germline and somatic BRCA1 mutations in ovarian cancer
-
Berchuck, A. et al. Frequency of germline and somatic BRCA1 mutations in ovarian cancer. Clin Cancer Res. 4, 2433-2437 (1998).
-
(1998)
Clin Cancer Res
, vol.4
, pp. 2433-2437
-
-
Berchuck, A.1
-
18
-
-
9444222467
-
Somatic and germlinemutations of the BRCA2 gene in sporadic ovarian cancer
-
Foster, K. A. et al. Somatic and germlinemutations of the BRCA2 gene in sporadic ovarian cancer. Cancer Res. 56, 3622-3625 (1996).
-
(1996)
Cancer Res
, vol.56
, pp. 3622-3625
-
-
Foster, K.A.1
-
19
-
-
79959838081
-
Integrated genomic analyses of ovarian carcinoma
-
Integrated genomic analyses of ovarian carcinoma. Nature 474, 609-615 (2011).
-
(2011)
Nature
, vol.474
, pp. 609-615
-
-
-
20
-
-
0034307160
-
BRCA1 promoter region hypermethylation in ovarian carcinoma: A population-based study
-
Baldwin, R. L. et al. BRCA1 promoter region hypermethylation in ovarian carcinoma: a population-based study. Cancer Res. 60, 5329-5333 (2000).
-
(2000)
Cancer Res
, vol.60
, pp. 5329-5333
-
-
Baldwin, R.L.1
-
21
-
-
77956645106
-
Methylation profiles of hereditary and sporadic ovarian cancer
-
Bol, G. M. et al. Methylation profiles of hereditary and sporadic ovarian cancer. Histopathology 57, 363-370 (2010).
-
(2010)
Histopathology
, vol.57
, pp. 363-370
-
-
Bol, G.M.1
-
22
-
-
0033970096
-
Tumour-specific distribution of BRCA1 promoter region methylation supports a pathogenetic role in breast and ovarian cancer
-
Bianco, T., Chenevix-Trench, G., Walsh, D. C., Cooper, J. E. & Dobrovic, A. Tumour-specific distribution of BRCA1 promoter region methylation supports a pathogenetic role in breast and ovarian cancer. Carcinogenesis 21, 147-151 (2000).
-
(2000)
Carcinogenesis
, vol.21
, pp. 147-151
-
-
Bianco, T.1
Chenevix-Trench, G.2
Walsh, D.C.3
Cooper, J.E.4
Dobrovic, A.5
-
23
-
-
84880298290
-
Keeping it simple: Genetics referrals for all invasive serous ovarian cancers
-
Demsky, R. et al. Keeping it simple: Genetics referrals for all invasive serous ovarian cancers. Gynecol Oncol. 130, 329-333 (2013).
-
(2013)
Gynecol Oncol
, vol.130
, pp. 329-333
-
-
Demsky, R.1
-
24
-
-
0033558282
-
Survival in familial, BRCA1-associated, and BRCA2-associated epithelial ovarian cancer
-
United Kingdom Coordinating Committee for Cancer Research (UKCCCR) Familial Ovarian Cancer Study Group
-
Pharoah, P. D., Easton, D. F., Stockton, D. L., Gayther, S. & Ponder, B. A. Survival in familial, BRCA1-associated, and BRCA2-associated epithelial ovarian cancer. United Kingdom Coordinating Committee for Cancer Research (UKCCCR) Familial Ovarian Cancer Study Group. Cancer Res. 59, 868-871 (1999).
-
(1999)
Cancer Res.
, vol.59
, pp. 868-871
-
-
Pharoah, P.D.1
Easton, D.F.2
Stockton, D.L.3
Gayther, S.4
Ponder, B.A.5
-
25
-
-
84860230447
-
Clinical characteristics and outcomes of BRCA-associated ovarian cancer: Genotype and survival
-
Liu, J. et al. Clinical characteristics and outcomes of BRCA-associated ovarian cancer: genotype and survival. Cancer Genet. 205, 34-41 (2012).
-
(2012)
Cancer Genet
, vol.205
, pp. 34-41
-
-
Liu, J.1
-
26
-
-
84856158117
-
Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer
-
Bolton, K. L. et al. Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer. Jama 307, 382-390 (2012).
-
(2012)
Jama
, vol.307
, pp. 382-390
-
-
Bolton, K.L.1
-
27
-
-
84864026311
-
BRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: A report from the Australian Ovarian Cancer Study Group
-
Alsop, K. et al. BRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group. J Clin Oncol. 30, 2654-2663 (2012).
-
(2012)
J Clin Oncol.
, vol.30
, pp. 2654-2663
-
-
Alsop, K.1
-
28
-
-
0036893150
-
The relationship between the roles of BRCA genes in DNA repair and cancer predisposition
-
Tutt, A. & Ashworth, A. The relationship between the roles of BRCA genes in DNA repair and cancer predisposition. Trends Mol Med. 8, 571-576 (2002).
-
(2002)
Trends Mol Med
, vol.8
, pp. 571-576
-
-
Tutt, A.1
Ashworth, A.2
-
29
-
-
77954032829
-
Poly(ADP)-ribose polymerase inhibition: Frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval
-
Fong, P. C. et al. Poly(ADP)-ribose polymerase inhibition: frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval. J Clin Oncol. 28, 2512-2519 (2010).
-
(2010)
J Clin Oncol
, vol.28
, pp. 2512-2519
-
-
Fong, P.C.1
-
30
-
-
84867547677
-
The role of PARP inhibitors in the treatment of ovarian carcinomas
-
Tinker, A. V. & Gelmon, K. The role of PARP inhibitors in the treatment of ovarian carcinomas. Curr Pharm Des. 18, 3770-3774 (2012).
-
(2012)
Curr Pharm des
, vol.18
, pp. 3770-3774
-
-
Tinker, A.V.1
Gelmon, K.2
-
31
-
-
81055126264
-
Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing
-
Walsh, T. et al. Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing. Proc Natl Acad Sci U.S.A. 108, 18032-18037 (2011).
-
(2011)
Proc Natl Acad Sci U.S.A
, vol.108
, pp. 18032-18037
-
-
Walsh, T.1
-
32
-
-
84891369796
-
Sytematic screen identifies miRNAs that target RAD51C and RAD51D to enhance chemotherapy
-
Huang, J. -W., Wang, Y., Dhillon, K. K., Calses, P., Villegas, E., Mitchell, P. S., Tewari,M., Kemp, C. J. & Tanaguchi, T. Sytematic screen identifies miRNAs that target RAD51C and RAD51D to enhance chemotherapy. Mol Cancer Res. 11, 1-10 (2013).
-
(2013)
Mol Cancer Res
, vol.11
, pp. 1-10
-
-
Huang, J.-W.1
Wang, Y.2
Dhillon, K.K.3
Calses, P.4
Villegas, E.5
Mitchell, P.S.6
Tewari, M.7
Kemp, C.J.8
Tanaguchi, T.9
-
33
-
-
84886376233
-
Biomarker-based ovarian carcinoma typing: A histologic investigation in the ovarian tumor tissue analysis consortium
-
Kobel, M. et al. Biomarker-based ovarian carcinoma typing: a histologic investigation in the ovarian tumor tissue analysis consortium. Cancer Epidemiol Biomarkers Prev. 22, 1677-1686 (2013).
-
(2013)
Cancer Epidemiol Biomarkers Prev
, vol.22
, pp. 1677-1686
-
-
Kobel, M.1
-
34
-
-
4944229642
-
Hallmarks of 'BRCAness' in sporadic cancers
-
Turner, N., Tutt, A.& Ashworth, A. Hallmarks of 'BRCAness' in sporadic cancers. Nat Rev Cancer 4, 814-819 (2004).
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 814-819
-
-
Turner, N.1
Tutt, A.2
Ashworth, A.3
-
35
-
-
57149093237
-
"BRCAness" syndrome in ovarian cancer: A case-control study describing the clinical features and outcome of patients with epithelial ovarian cancer associated with BRCA1 and BRCA2 mutations
-
Tan, D. S. et al. "BRCAness" syndrome in ovarian cancer: a case-control study describing the clinical features and outcome of patients with epithelial ovarian cancer associated with BRCA1 and BRCA2 mutations. J Clin Oncol. 26, 5530-5536 (2008).
-
(2008)
J Clin Oncol
, vol.26
, pp. 5530-5536
-
-
Tan, D.S.1
-
36
-
-
80053259851
-
RAD51C germline mutations in breast and ovarian cancer cases from high-risk families
-
Clague, J. et al. RAD51C germline mutations in breast and ovarian cancer cases from high-risk families. PLoS One 6, e25632 (2011).
-
(2011)
PLoS One
, vol.6
-
-
Clague, J.1
-
37
-
-
84874955840
-
Germline RAD51C mutations in ovarian cancer susceptibility
-
Coulet, F. et al.Germline RAD51C mutations in ovarian cancer susceptibility. Clin Genet. 83, 332-336 (2013).
-
(2013)
Clin Genet
, vol.83
, pp. 332-336
-
-
Coulet, F.1
-
38
-
-
84867784222
-
Constitutive promoter methylation of BRCA1 and RAD51C in patients with familial ovarian cancer and early-onset sporadic breast cancer
-
Hansmann, T. et al. Constitutive promoter methylation of BRCA1 and RAD51C in patients with familial ovarian cancer and early-onset sporadic breast cancer. Hum Mol Genet. 21, 4669-4679 (2012).
-
(2012)
Hum Mol Genet
, vol.21
, pp. 4669-4679
-
-
Hansmann, T.1
-
39
-
-
84860320440
-
Germline RAD51C mutations confer susceptibility to ovarian cancer
-
Loveday, C. et al. Germline RAD51C mutations confer susceptibility to ovarian cancer. Nat Genet. 44, 475-476 (2012).
-
(2012)
Nat Genet
, vol.44
, pp. 475-476
-
-
Loveday, C.1
-
40
-
-
84869079205
-
Patterns of genomic loss of heterozygosity predict homologous recombination repair defects in epithelial ovarian cancer
-
Abkevich, V. et al. Patterns of genomic loss of heterozygosity predict homologous recombination repair defects in epithelial ovarian cancer. Br J Cancer 107, 1776-1782 (2012).
-
(2012)
Br J Cancer
, vol.107
, pp. 1776-1782
-
-
Abkevich, V.1
-
41
-
-
84872517041
-
Long-term ovarian cancer survival associated with mutation in BRCA1 or BRCA2
-
McLaughlin, J. R. et al. Long-term ovarian cancer survival associated with mutation in BRCA1 or BRCA2. J Natl Cancer Inst. 105, 141-148 (2013).
-
(2013)
J Natl Cancer Inst
, vol.105
, pp. 141-148
-
-
McLaughlin, J.R.1
-
42
-
-
84864053120
-
BRCAness: Finding the achilles heel in ovarian cancer
-
Rigakos, G. & Razis, E. BRCAness: Finding the achilles heel in ovarian cancer. Oncologist 17, 956-962 (2012).
-
(2012)
Oncologist
, vol.17
, pp. 956-962
-
-
Rigakos, G.1
Razis, E.2
-
43
-
-
79961231255
-
Assessment of hepatocyte growth factor in ovarian cancer mortality
-
Goode, E. L. et al. Assessment of hepatocyte growth factor in ovarian cancer mortality. Cancer Epidemiol Biomarkers Prev. 20, 1638-1648 (2011).
-
(2011)
Cancer Epidemiol Biomarkers Prev
, vol.20
, pp. 1638-1648
-
-
Goode, E.L.1
-
44
-
-
77956295988
-
The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
-
McKenna, A. et al. The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data. Genome Res. 20, 1297-1303 (2010).
-
(2010)
Genome Res
, vol.20
, pp. 1297-1303
-
-
McKenna, A.1
-
45
-
-
84856565531
-
SomaticSniper: Identification of somatic point mutations in whole genome sequencing data
-
Larson, D. E. et al. SomaticSniper: identification of somatic point mutations in whole genome sequencing data. Bioinformatics 28, 311-317 (2012).
-
(2012)
Bioinformatics
, vol.28
, pp. 311-317
-
-
Larson, D.E.1
-
46
-
-
84862929636
-
TREAT: A bioinformatics tool for variant annotations and visualizations in targeted and exome sequencing data
-
Asmann, Y. W. et al. TREAT: a bioinformatics tool for variant annotations and visualizations in targeted and exome sequencing data. Bioinformatics 28, 277-278 (2012).
-
(2012)
Bioinformatics
, vol.28
, pp. 277-278
-
-
Asmann, Y.W.1
-
47
-
-
84879580092
-
Epigenome-wide ovarian cancer analysis identifies a methylation profile differentiating clear-cell histology with epigenetic silencing of the HERG K1 channel
-
Cicek, M. S. et al. Epigenome-wide ovarian cancer analysis identifies a methylation profile differentiating clear-cell histology with epigenetic silencing of the HERG K1 channel. Hum Mol Genet. 22, 3038-3047(2013).
-
(2013)
Hum Mol Genet
, vol.22
, pp. 3038-3047
-
-
Cicek, M.S.1
|