In vitro and in vivo genotoxicity assessment of HI-6 dimethanesulfonate/oxime

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 762, Issue , 2014, Pages 30-38

  Nakab, Lauren ^a   Bardot, Isabelle ^c   Bardot, Sébastien ^c   Simar, Sophie ^a   Marzin, Daniel ^a,b   Nesslany, Fabrice ^a,b  

^a INSTITUT PASTEUR DE LILLE   (France)

^b UFR3S Pharmacie   (France)

^c TSA 30004 ^*  (France)

Author keywords

Genotoxicity; Organophosphate poisoning; Oxime

Indexed keywords

1 (4 CARBAMOYLPYRIDINIO) 1' (2 HYDROXYIMINOMETHYLPYRIDINIO)DIMETHYL ETHER; ACETYLCHOLINESTERASE;

AMES TEST; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE MARROW; COMET ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DNA STRAND BREAKAGE; DOSE RESPONSE; DRUG POTENCY; DRUG SOLUBILITY; GENOTOXICITY; IN VITRO STUDY; IN VIVO STUDY; MALE; METABOLIC ACTIVATION; MICRONUCLEUS TEST; MOUSE; MUTAGENIC ACTIVITY; MUTAGENICITY; MUTATION RATE; NONHUMAN; PRIORITY JOURNAL; RAT;

GENOTOXICITY; ORGANOPHOSPHATE POISONING; OXIME;

ANIMALS; BONE MARROW CELLS; CELL LINE, TUMOR; COMET ASSAY; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; INJECTIONS, INTRAPERITONEAL; LIVER; MALE; METHYL METHANESULFONATE; MICE; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MOLECULAR STRUCTURE; MUTAGENS; OXIMES; PYRIDINIUM COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY; SALMONELLA TYPHIMURIUM;

EID: 84896776274     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2013.11.006     Document Type: Article

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