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Volumn 4, Issue , 2014, Pages

Dll4-containing exosomes induce capillary sprout retraction in a 3D microenvironment

Author keywords

[No Author keywords available]

Indexed keywords

DLL4 PROTEIN, HUMAN; NOTCH RECEPTOR; SIGNAL PEPTIDE; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2, HUMAN; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2, HUMAN; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2; VEGFA PROTEIN, HUMAN;

EID: 84896772471     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep04031     Document Type: Article
Times cited : (92)

References (37)
  • 1
    • 77957241701 scopus 로고    scopus 로고
    • Dynamics of endothelial cell behavior in sprouting angiogenesis
    • Eilken, H.M. & Adams, R. H. Dynamics of endothelial cell behavior in sprouting angiogenesis. Curr Opin Cell Biol. 22, 617-625 (2010).
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 617-625
    • Eilken, H.M.1    Adams, R.H.2
  • 2
    • 0037815292 scopus 로고    scopus 로고
    • VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia
    • Gerhardt, H. et al. VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia. J Cell Biol. 161, 1163-1177 (2003).
    • (2003) J Cell Biol. , vol.161 , pp. 1163-1177
    • Gerhardt, H.1
  • 3
    • 0037108152 scopus 로고    scopus 로고
    • Spatially restricted patterning cues provided by heparinbinding VEGF-A control blood vessel branching morphogenesis
    • Ruhrberg, C. et al. Spatially restricted patterning cues provided by heparinbinding VEGF-A control blood vessel branching morphogenesis. Genes Dev. 16, 2684-2698 (2002).
    • (2002) Genes Dev , vol.16 , pp. 2684-2698
    • Ruhrberg, C.1
  • 4
    • 35349012675 scopus 로고    scopus 로고
    • Regulation of vascular morphogenesis by Notch signaling
    • Roca, C. & Adams, R. H. Regulation of vascular morphogenesis by Notch signaling. Genes Dev. 21, 2511-2524 (2007).
    • (2007) Genes Dev , vol.21 , pp. 2511-2524
    • Roca, C.1    Adams, R.H.2
  • 5
    • 0030748716 scopus 로고    scopus 로고
    • The ins and outs of notch signaling
    • Weinmaster, G. The ins and outs of notch signaling. Mol Cell Neurosci. 9, 91-102 (1997).
    • (1997) Mol Cell Neurosci , vol.9 , pp. 91-102
    • Weinmaster, G.1
  • 6
    • 0142259346 scopus 로고    scopus 로고
    • The role of Notch in tumorigenesis: Oncogene or tumour suppressor?
    • Radtke, F. & Raj, K. The role of Notch in tumorigenesis: oncogene or tumour suppressor? Nat Rev Cancer. 3, 756-767 (2003).
    • (2003) Nat Rev Cancer , vol.3 , pp. 756-767
    • Radtke, F.1    Raj, K.2
  • 8
    • 59649085554 scopus 로고    scopus 로고
    • Angiogenesis: A team effort coordinated by notch
    • Phng, L. K. & Gerhardt, H. Angiogenesis: a team effort coordinated by notch. Dev Cell. 16, 196-208 (2009).
    • (2009) Dev Cell. , vol.16 , pp. 196-208
    • Phng, L.K.1    Gerhardt, H.2
  • 10
    • 33847607880 scopus 로고    scopus 로고
    • The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching
    • Suchting, S. et al. The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching. Proc Natl Acad Sci U S A. 104, 3225-3230 (2007).
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 3225-3230
    • Suchting, S.1
  • 11
    • 33845877157 scopus 로고    scopus 로고
    • Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis
    • Noguera-Troise, I. et al. Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis. Nature. 444, 1032-1037 (2006).
    • (2006) Nature , vol.444 , pp. 1032-1037
    • Noguera-Troise, I.1
  • 12
    • 33847046849 scopus 로고    scopus 로고
    • Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis
    • Hellstro?m,M. et al.Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature. 445, 776-780 (2007).
    • (2007) Nature , vol.445 , pp. 776-780
    • Hellstrom, M.1
  • 13
    • 77956335736 scopus 로고    scopus 로고
    • Novel insights into the differential functions ofNotch ligands in vascular formation
    • Kume, T.Novel insights into the differential functions ofNotch ligands in vascular formation. Journal of angiogenesis research. 1, 8 (2009).
    • (2009) Journal of Angiogenesis Research , vol.1 , pp. 8
    • Kume, T.1
  • 14
    • 77957607057 scopus 로고    scopus 로고
    • Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting
    • Jakobsson, L. et al. Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting. Nat Cell Biol. 12, 943-953 (2010).
    • (2010) Nat Cell Biol , vol.12 , pp. 943-953
    • Jakobsson, L.1
  • 15
    • 77957708340 scopus 로고    scopus 로고
    • New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes
    • Sheldon, H. et al. New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes. Blood. 116, 2385-2394 (2010).
    • (2010) Blood , vol.116 , pp. 2385-2394
    • Sheldon, H.1
  • 16
    • 77958098024 scopus 로고    scopus 로고
    • Exosomes/microvesicles as a mechanism of cell-to-cell communication
    • Camussi, G., Deregibus, M. C., Bruno, S., Cantaluppi, V. & Biancone, L. Exosomes/microvesicles as a mechanism of cell-to-cell communication. Kidney Int. 78, 838-848 (2010).
    • (2010) Kidney Int , vol.78 , pp. 838-848
    • Camussi, G.1    Deregibus, M.C.2    Bruno, S.3    Cantaluppi, V.4    Biancone, L.5
  • 18
    • 79551542416 scopus 로고    scopus 로고
    • Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis
    • Fitzner, D. et al. Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis. J Cell Sci. 124, 447-458 (2011).
    • (2011) J Cell Sci , vol.124 , pp. 447-458
    • Fitzner, D.1
  • 19
    • 71749102668 scopus 로고    scopus 로고
    • Microenvironmental pH is a key factor for exosome traffic in tumor cells
    • Parolini, I. et al. Microenvironmental pH is a key factor for exosome traffic in tumor cells. J Biol Chem. 284, 34211-34222 (2009).
    • (2009) J Biol Chem , vol.284 , pp. 34211-34222
    • Parolini, I.1
  • 20
    • 77953154769 scopus 로고    scopus 로고
    • Cellular internalization of exosomes occurs through phagocytosis
    • Feng, D. et al. Cellular internalization of exosomes occurs through phagocytosis. Traffic. 11, 675-687 (2010).
    • (2010) Traffic , vol.11 , pp. 675-687
    • Feng, D.1
  • 21
    • 8644286802 scopus 로고    scopus 로고
    • Endocytosis, intracellular sorting, and processing of exosomes by dendritic cells
    • Morelli, A. E. et al. Endocytosis, intracellular sorting, and processing of exosomes by dendritic cells. Blood. 104, 3257-3266 (2004).
    • (2004) Blood , vol.104 , pp. 3257-3266
    • Morelli, A.E.1
  • 22
    • 84879046970 scopus 로고    scopus 로고
    • Exosome uptake depends on ERK1/2-heat shock protein 27 signaling and lipid Raft-mediated endocytosis negatively regulated by caveolin-1
    • Svensson, K. J. et al. Exosome uptake depends on ERK1/2-heat shock protein 27 signaling and lipid Raft-mediated endocytosis negatively regulated by caveolin-1. J Biol Chem. 288, 17713-17724 (2013).
    • (2013) J Biol Chem , vol.288 , pp. 17713-17724
    • Svensson, K.J.1
  • 23
    • 84861467738 scopus 로고    scopus 로고
    • Ensemble analysis of angiogenic growth in three-dimensional microfluidic cell cultures
    • Farahat, W. A. et al. Ensemble analysis of angiogenic growth in three-dimensional microfluidic cell cultures. PloS one. 7, e37333 (2012).
    • (2012) PloS One , vol.7
    • Farahat, W.A.1
  • 24
    • 43249109372 scopus 로고    scopus 로고
    • Isolation and characterization of exosomes from cell culture supernatants and biological fluids
    • Chapter 3, Unit 3.22
    • The'ry, C., Amigorena, S., Raposo, G. & Clayton, A. Isolation and characterization of exosomes from cell culture supernatants and biological fluids. Curr Protoc Cell Biol. Chapter 3, Unit 3.22 (2006).
    • (2006) Curr Protoc Cell Biol.
    • The'Ry, C.1    Amigorena, S.2    Raposo, G.3    Clayton, A.4
  • 26
    • 39149123515 scopus 로고    scopus 로고
    • Regulation of multiple angiogenic pathways by Dll4 and Notch in human umbilical vein endothelial cells
    • Harrington, L. S. et al. Regulation of multiple angiogenic pathways by Dll4 and Notch in human umbilical vein endothelial cells. Microvasc Res. 75, 144-154 (2008).
    • (2008) Microvasc Res , vol.75 , pp. 144-154
    • Harrington, L.S.1
  • 27
    • 48249103470 scopus 로고    scopus 로고
    • Slug is a direct Notch target required for initiation of cardiac cushion cellularization
    • Niessen, K. et al. Slug is a direct Notch target required for initiation of cardiac cushion cellularization. J Cell Biol. 182, 315-325 (2008).
    • (2008) J Cell Biol , vol.182 , pp. 315-325
    • Niessen, K.1
  • 28
    • 4744358492 scopus 로고    scopus 로고
    • Notch activation induces endothelial cell cycle arrest and participates in contact inhibition: Role of p21Cip1 repression
    • Noseda, M. et al. Notch activation induces endothelial cell cycle arrest and participates in contact inhibition: role of p21Cip1 repression. Mol Cell Biol. 24, 8813-8822 (2004).
    • (2004) Mol Cell Biol , vol.24 , pp. 8813-8822
    • Noseda, M.1
  • 29
    • 31544448010 scopus 로고    scopus 로고
    • Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell function
    • Williams, C. K., Li, J. L.,Murga, M.,Harris, A. L.&Tosato,G. Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell function. Blood. 107, 931-939 (2006).
    • (2006) Blood , vol.107 , pp. 931-939
    • Williams, C.K.1    Li, J.L.2    Murga, M.3    Harris, A.L.4    Tosato, G.5
  • 30
    • 79955481749 scopus 로고    scopus 로고
    • Exosomes as intercellular signalosomes and pharmacological effectors
    • Record, M., Subra, C., Silvente-Poirot, S. & Poirot, M. Exosomes as intercellular signalosomes and pharmacological effectors. Biochem Pharmacol. 81, 1171-1182 (2011).
    • (2011) Biochem Pharmacol , vol.81 , pp. 1171-1182
    • Record, M.1    Subra, C.2    Silvente-Poirot, S.3    Poirot, M.4
  • 31
    • 48349129069 scopus 로고    scopus 로고
    • Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation
    • Tammela, T. et al. Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation. Nature. 454, 656-660 (2008).
    • (2008) Nature , vol.454 , pp. 656-660
    • Tammela, T.1
  • 32
    • 0036433637 scopus 로고    scopus 로고
    • Notch activation during endothelial cell network formation in vitro targets the basic HLH transcription factor HESR-1 and downregulates VEGFR-2/KDR expression
    • Taylor, K. L., Henderson, A. M. & Hughes, C. C. W. Notch activation during endothelial cell network formation in vitro targets the basic HLH transcription factor HESR-1 and downregulates VEGFR-2/KDR expression. Microvasc Res. 64, 372-383 (2002).
    • (2002) Microvasc Res , vol.64 , pp. 372-383
    • Taylor, K.L.1    Henderson, A.M.2    Hughes, C.C.W.3
  • 33
    • 0034212710 scopus 로고    scopus 로고
    • Notch signaling is essential for vascular morphogenesis in mice
    • Krebs, L. T. et al. Notch signaling is essential for vascular morphogenesis in mice. Genes Dev. 14, 1343-1352 (2000).
    • (2000) Genes Dev , vol.14 , pp. 1343-1352
    • Krebs, L.T.1
  • 34
    • 84876927914 scopus 로고    scopus 로고
    • Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development
    • Kucharzewska, P. et al. Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development. Proc Natl Acad Sci U S A. 110, 7312-7317 (2013).
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 7312-7317
    • Kucharzewska, P.1
  • 35
    • 58849144604 scopus 로고    scopus 로고
    • Tumor-induced upregulation of Twist, Snail, and Slug represses the activity of the human VE-cadherin promoter
    • Lopez, D., Niu, G., Huber, P. & Carter, W. B. Tumor-induced upregulation of Twist, Snail, and Slug represses the activity of the human VE-cadherin promoter. Arch Biochem Biophys. 482, 77-82 (2009).
    • (2009) Arch Biochem Biophys , vol.482 , pp. 77-82
    • Lopez, D.1    Niu, G.2    Huber, P.3    Carter, W.B.4
  • 36
    • 44349119736 scopus 로고    scopus 로고
    • Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration
    • Graupera, M. et al. Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration. Nature. 453, 662-666 (2008).
    • (2008) Nature , vol.453 , pp. 662-666
    • Graupera, M.1
  • 37
    • 1542571789 scopus 로고    scopus 로고
    • Neuropilin-1-mediated vascular permeability factor/vascular endothelial growth factordependent endothelial cell migration
    • Wang, L., Zeng, H., Wang, P., Soker, S. & Mukhopadhyay, D. Neuropilin-1- mediated vascular permeability factor/vascular endothelial growth factordependent endothelial cell migration. J Biol Chem. 278, 48848-48860 (2003).
    • (2003) J Biol Chem , vol.278 , pp. 48848-48860
    • Wang, L.1    Zeng, H.2    Wang, P.3    Soker, S.4    Mukhopadhyay, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.