Circulating immunoglobulins are not associated with intraplaque mast cell number and other vulnerable plaque characteristics in patients with carotid artery stenosis

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Willems, Sanne ^a   Van Velden, Daniël Der ^b   Quax, Paul H A ^c   De Borst, Gert Jan ^a   De Vries, Jean Paul P M ^d   Moll, Frans L ^a   Kuiper, Johan ^b   Toes, René E M ^c   De Jager, Saskia C A ^a   De Kleijn, Dominique P V ^a,e,f   Hoefer, Imo E ^a   Pasterkamp, Gerard ^a   Bot, Ilze ^b,c  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^d ST ANTONIUS HOSPITAL   (Netherlands)

^e ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

^f NATIONAL UNIVERSITY HOSPITAL   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; OXIDIZED LOW DENSITY LIPOPROTEIN ANTIBODY; TRYPTASE; LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN;

AGED; ARTICLE; ATHEROSCLEROTIC PLAQUE; CAPILLARY DENSITY; CAROTID ARTERY OBSTRUCTION; CAROTID ENDARTERECTOMY; CELL ACTIVATION; CELL COUNT; ENZYME BLOOD LEVEL; FEMALE; HUMAN; HUMAN CELL; IMMUNOGLOBULIN BLOOD LEVEL; LIPID STORAGE; MACROPHAGE; MAJOR CLINICAL STUDY; MALE; MAST CELL; MAST CELL DEGRANULATION; SMOOTH MUSCLE FIBER; BLOOD; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; NONPARAMETRIC TEST; PATHOLOGY;

CAROTID STENOSIS; ENDARTERECTOMY, CAROTID; HUMANS; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOHISTOCHEMISTRY; LIPOPROTEINS, LDL; MAST CELLS; STATISTICS, NONPARAMETRIC;

EID: 84896764534     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0088984     Document Type: Article

References (25)

1. Kaartinen M, Penttilä A, Kovanen PT (1994) Accumulation of activated mast cells in the shoulder region of human coronary atheroma, the predilection site of atheromatous rupture. Circulation 90: 1669-1678. (Pubitemid 24320913)
2. Kovanen P, Kaartinen M, Paavonen T (1995) Infiltrates of activated mast cells at the site of coronary atheromatous erosion or rupture in myocardial infarction. Circulation 92: 1084-1088.
3. Laine P, Kaartinen M, Penttilä A, Panula P, Paavonen T, et al. (1999) Association between myocardial infarction and the mast cells in the adventitia of the infarct-related coronary artery. Circulation 124: 297-303.
4. Willems S, Vink A, Bot I, Quax PH, de Borst GJ, et al. (2013) Mast cells in human carotid atherosclerotic plaques are associated with intraplaque microvessel density and the occurrence of future cardiovascular events. Eur Heart J 34: 3699-3706.
5. Bot I, de Jager SC, Bot M, van Heiningen SH, de Groot P, et al. (2010) The neuropeptide Substance P mediates adventitial mast cell activation and induces intraplaque hemorrhage in advanced atherosclerosis. Circ Res 106: 89-92.
6. De Vries MR, Wezel A, Schepers A, van Santbrink PJ, Woodruff TM, et al. (2013) Complement factor C5a as mast cell activator mediates vascular remodelling in vein graft disease. Cardiovasc Res 97: 311-320.
7. Bot M, de Jager SC, MacAleese L, Lagraauw HM, van Berkel TJ, et al. (2013) Lysophosphatidic acid triggers mast cell-driven atherosclerotic plaque destabilization by increasing vascular inflammation. J Lipid Res 54: 1265-1274.
8. Kalesnikoff J, Galli SJ (2008) New developments in mast cell biology. Nat Immunol 9: 1215-1223.
9. Malbec O, Daëron M (2007) The mast cell IgG receptors and their roles in tissue inflammation. Immunol Rev 217: 206-221.
10. Korkmaz ME, Oto A, Saraçlar Y, Oram E, Oram A, et al. (1991) Levels of IgE in the serum of patients with coronary arterial disease. Int J Cardiol 31: 199-204.
11. Kovanen PT, Mänttäri M, Palosuo T, Manninen V, Aho K (1998) Prediction of myocardial infarction in dyslipidemic men by elevated levels of immunoglobulin classes A, E, and G, but not M. Arch Intern Med 13: 1434-1439. (Pubitemid 28317759)
12. Lappalainen J, Lindstedt KA, Oksjoki R, Kovanen PT (2011) OxLDL-IgG immune complexes induce expression and secretion of proatherogenic cytokines by cultured human mast cells. Atherosclerosis 214: 357-363.
13. Verhoeven BA, Velema E, Schoneveld AH, de Vries JP, de Bruin P, et al. (2004) Athero-express: differential atherosclerotic plaque expression of mRNA and protein in relation to cardiovascular events and patient characteristics. Rationale and design. Eur J Epidemiol 19: 1127-1133. (Pubitemid 40228502)
14. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study (1995) Endarterectomy for asymptomatic carotid artery stenosis. Executive committee for the asymptomatic carotid atherosclerosis study. JAMA 273: 1421-1428.
15. Toole JF (1996) ACAS recommendations for carotid endarterectomy. ACAS Executive Committee. Lancet 347: 12.
16. Halliday A, Mansfield A, Marro J, Peto C, Peto R, et al. (2004) Prevention of disabling and fatal strokes by succesful carotid endarterectomy in patients without recent neurological symptoms. Randomised controlled trial. Lancet 363: 1491-1502.
17. Rothwell PM, Eliasziw M, Gutnikov SA, Fox AJ, Taylor DW, et al. (2003) Analysis of pooled data from the randomised controlled trials of endarterectomy for symptomatic carotid stenosis. Lancet 361: 107-116. (Pubitemid 36092014)
18. Coyne TJ, Wallace MC (1994) Surgical referral for carotid artery stenosis-the influence of NASCET. North American Symptomatic Carotid Endarterectomy Trial. Can J Neurol Sci 21: 129-132. (Pubitemid 24174902)
19. Hellings WE, Peeters W, Moll FL, Piers SR, van Setten J, et al. (2010) Composition of carotid atherosclerotic plaque is associated with cardiovascular outcome: a prognostic study. Circulation 121: 1941-1950.
20. Bot I, de Jager SC, Zernecke A, Lindstedt KA, van Berkel TJ, et al. (2007) Perivascular mast cells promote atherogenesis and induce plaque destabilization in apolipoprotein E-deficient mice. Circulation 115: 2516-25. (Pubitemid 46763225)
21. Sun J, Sukhova GK, Wolters PJ, Yang M, Kitamoto S, et al. (2007) Mast cells promote atherosclerosis by releasing proinflammatory cytokines. Nat Med 13: 719-24. (Pubitemid 46889760)
22. Wang J, Cheng X, Xiang MX, Alanne-Kinnunen M, Wang JA, et al. (2011) IgE stimulates human and mouse arterial cell apoptosis and cytokine expression and promotes atherogenesis in Apoe2/2 mice. J Clin Invest 121: 3564-3577.
23. Ylä-Herttuala S, Palinski W, Butler SW, Picard S, Steinberg D, et al. (1994) Rabbit and human atherosclerotic lesions contain IgG that recognizes epitopes of oxidized LDL. Atheroscl Thromb Vasc Biol 14: 32-40.
24. Criqui MH, Lee ER, Hamburger RN, Klauber MR, Coughlin SS (1987) IgE and cardiovascular disease. Results from a population-based study. Am J Med 82: 964-968.
25. Laczik R, Szodoray P, Veres K, Szomják E, Csípo I, et al. (2011) Assessment of IgG antibodies to oxidized LDL in patients with acute coronary syndrome. Lupus 20: 730-735.