Short communication: The neuropeptide substance P mediates adventitial mast cell activation and induces intraplaque hemorrhage in advanced atherosclerosis

Circulation Research

Volumn 106, Issue 1, 2010, Pages 89-92

  Bot, Ilze ^a   De Jager, Saskia C A ^a   Bot, Martine ^a   Van Heiningen, Sandra H ^a   De Groot, Paul ^b   Veldhuizen, Roel W ^b   Van Berkel, Theo J C ^c   Von Der Thüsen, Jan H ^a   Biessen, Erik A L ^a,d  

^a LEIDEN UNIVERSITY   (Netherlands)

^b MEDICAL CENTER HAAGLANDEN   (Netherlands)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

^d MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Atherosclerosis; Hemorrhage; Mast cells; Neuropeptides; Substance P

Indexed keywords

APOLIPOPROTEIN E; SPANTIDE; STEM CELL FACTOR RECEPTOR; SUBSTANCE P; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; ANALGESIC AGENT; DRUG DERIVATIVE; NEUROKININ 1 RECEPTOR;

ADVENTITIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; BLEEDING; CELL MIGRATION; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; INFLAMMATION; MALE; MAST CELL; MOUSE; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; AGED; ANIMAL; CAROTID ARTERY; CONNECTIVE TISSUE; CORONARY ARTERY DISEASE; DRUG ANTAGONISM; FEMALE; GENETICS; METABOLISM; MOUSE MUTANT; PATHOLOGY; VASCULITIS;

AGED; ANALGESICS; ANIMALS; APOLIPOPROTEINS E; CAROTID ARTERIES; CONNECTIVE TISSUE; CORONARY ARTERY DISEASE; FEMALE; HEMORRHAGE; HUMANS; MALE; MAST CELLS; MICE; MICE, KNOCKOUT; NEUROTRANSMITTER AGENTS; RECEPTORS, NEUROKININ-1; SUBSTANCE P; VASCULITIS;

EID: 74049118506     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.109.204875     Document Type: Article

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