Thromboresistance comparison of the heartmate II ventricular assist device with the device thrombogenicity emulation-optimized heartassist 5 VAD

Journal of Biomechanical Engineering

Volumn 136, Issue 2, 2014, Pages

  Chiu, Wei Che ^a   Girdhar, Gaurav ^a   Xenos, Michalis ^a   Alemu, Yared ^a   Einav, Shmuel ^a   Slepian, Marvin ^a   Bluestein, Danny ^a  

^a St Francis Hospital The Heart Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOVASCULAR DEVICES; COMPARATIVE STUDIES; DESTINATION THERAPY; MECHANICAL DURABILITY; NUMERICAL FLOW SIMULATIONS; OPTIMIZATION METHODOLOGY; RE-CIRCULATION FLOW; VENTRICULAR ASSIST DEVICE;

FIBER OPTIC SENSORS; PLATELETS; PROBABILITY DENSITY FUNCTION;

OPTIMIZATION;

ARTICLE; BLOOD CLOTTING; BLOOD FLOW; COMPARATIVE STUDY; CONTROLLED STUDY; IN VITRO STUDY; SIMULATION; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOGENICITY; VENTRICULAR ASSIST DEVICE; BIOLOGICAL MODEL; BLOOD FLOW VELOCITY; BLOOD PRESSURE; COMPUTER SIMULATION; DEVICE FAILURE ANALYSIS; HEART ASSIST DEVICE; HEART VENTRICLE; HUMAN; PATHOPHYSIOLOGY; PROSTHESIS; SURGERY; THROMBOSIS;

BLOOD FLOW VELOCITY; BLOOD PRESSURE; COMPUTER SIMULATION; EQUIPMENT FAILURE ANALYSIS; HEART VENTRICLES; HEART-ASSIST DEVICES; HUMANS; MODELS, CARDIOVASCULAR; PROSTHESIS DESIGN; THROMBOSIS;

EID: 84896743761     PISSN: 01480731     EISSN: 15288951     Source Type: Journal    
DOI: 10.1115/1.4026254     Document Type: Article

References (31)

1. Go, A. S., Mozaffarian, D., Roger, V. L., Benjamin, E. J., Berry, J. D., Borden, W. B., Bravata, D. M., Dai, S., Ford, E. S., Fox, C. S., Franco, S., Fullerton, H. J., Gillespie, C., Hailpern, S. M., Heit, J. A., Howard, V. J., Huffman, M. D., Kissela, B. M., Kittner, S. J., Lackland, D. T., Lichtman, J. H., Lisabeth, L. D., Magid, D., Marcus, G. M., Marelli, A., Matchar, D. B., Mcguire, D. K., Mohler, E. R., Moy, C. S., Mussolino, M. E., Nichol, G., Paynter, N. P., Schreiner, P. J., Sorlie, P. D., Stein, J., Turan, T. N., Virani, S. S., Wong, N. D., Woo, D., and Turner, M. B., 2013, "Heart Disease and Stroke Statistics-2013 Update: A Report from the American Heart Association," Circulation, 127(1), pp. e6-e245.
2. Kurihara, C., Ono, M., Nishimura, T., Nawata, K., Kinoshita, O., Hisagi, M., Motomura, N., and Kyo, S., 2011, "Prolonged Biventricular Assist Device Support as a Bridge to Heart Transplantation," Int. J. Artif. Organs, 14(4), pp. 367-370.
3. Copeland, J. G., Copeland, H., Gustafson, M., Mineburg, N., Covington, D., Smith, R. G., and Friedman, M., 2012, "Experience With More Than 100 Total Artificial Heart Implants," J Thorac. Cardiovasc. Surg., 143(3), pp. 727-734.
4. Srtr, 2011, Optn/Srtr 2011, "Annual Data Report: Heart." Available at: http://srtr.transplant.hrsa.gov/annual-reports/2011/
5. Kirklin, J. K., Naftel, D. C., Kormos, R. L., Stevenson, L. W., Pagani, F. D., Miller, M. A., Baldwin, J. T., and Young, J. B., 2012, "The Fourth Intermacs Annual Report: 4,000 Implants and Counting," J. Heart Lung Transplant, 31(2), pp. 117-126.
6. Slaughter, M. S., Rogers, J. G., Milano, C. A., Russell, S. D., Conte, J. V., Feldman, D., Sun, B., Tatooles, A. J., Delgado, R. M. III, Long, J. W., Wozniak, T. C., Ghumman, W., Farrar, D. J., and Frazier, O. H., 2009, "Advanced Heart Failure Treated With Continuous-Flow Left Ventricular Assist Device," N. Engl. J. Med., 361(23), pp. 2241-2251.
7. Lahpor, J. R., 2009, "State of the Art: Implantable Ventricular Assist Devices," Curr. Opin. Organ Transplant, 14(5), pp. 554-559.
8. Carrel, T., Englberger, L., Martinelli, M. V., Takala, J., Boesch, C., Sigurdadottir, V., Gygax, E., Kadner, A., and Mohacsi, P., 2012, "Continuous Flow Left Ventricular Assist Devices: A Valid Option for Heart Failure Patients," Swiss Med. Wkly., 142, pp. w13701.
9. Heilmann, C., Geisen, U., Benk, C., Berchtold-Herz, M., Trummer, G., Schlensak, C., Zieger, B., and Beyersdorf, F., 2009, "Haemolysis in Patients With Ventricular Assist Devices: Major Differences Between Systems," Eur. J. Cardiothorac. Surg., 3636, pp. 580-584.
10. Snyder, T. A., Watach, M. J., Litwak, K. N., and Wagner, W. R., 2002, "Platelet Activation, Aggregation, and Life Span in Calves Implanted With Axial Flow Ventricular Assist Devices," Ann. Thorac. Surg., 73, pp. 1933-1938. (Pubitemid 34596744)
11. Girdhar, G., Xenos, M., Alemu, Y., Chiu, W. C., Lynch, B. E., Jesty, J., Einav, S., Slepian, M. J., and Bluestein, D., 2012, "Device Thrombogenicity Emulation: A Novel Method for Optimizing Mechanical Circulatory Support Device Thromboresistance," PLoS ONE, 7(3), p. e32463.
12. Mokadam, N. A., Andrus, S., and Ungerleider, A., 2011, "Thrombus Formation in a Heartmate Ii," Eur. J. Cardiothorac. Surg., 39(3), p. 414.
13. Meyer, A. L., Kuehn, C.,Weidemann, J.,Malehsa, D., Bara, C., Fischer, S., Haverich, A., and Struber, M., 2008, "Thrombus Formation in a Heartmate Ii Left Ventricular Assist Device," J. Thorac. Cardiovasc. Surg., 135(1), pp. 203-204.
14. Najib, M. Q., Wong, R. K., Pierce, C. N., Devaleria, P. A., and Chaliki, H. P., 2012, "An Unusual Presentation of Left Ventricular Assist Device Thrombus," Eur. Heart J. Cardiovasc. Imaging, 13(6), p. 532.
15. Pappalardo, F., Scandroglio, A. M., Potapov, E., Stepanenko, A., Maj, G., Krabatsch, T., Zangrillo, A., Koster, A., and Hetzer, R., 2012, "Argatroban Anticoagulation for Heparin Induced Thrombocytopenia in Patients With Ventricular Assist Devices," Minerva Anestesiol., 78(3), pp. 330-335.
16. Geisen, U., Heilmann, C., Beyersdorf, F., Benk, C., Berchtold-Herz, M., Schlensak, C., Budde, U., and Zieger, B., 2008, "Non-Surgical Bleeding in Patients With Ventricular Assist Devices Could Be Explained by Acquired Von Willebrand Disease," Eur. J. Cardiothorac. Surg., 33(4), pp. 679-684.
17. Meyer, A. L., Malehsa, D., Bara, C., Budde, U., Slaughter, M. S., Haverich, A., and Strueber, M., 2010, "Acquired Von Willebrand Syndrome in Patients With an Axial Flow Left Ventricular Assist Device," Circ. Heart Fail, 3(6), pp. 675-681.
18. Malehsa, D., Meyer, A. L., Bara, C., and Struber, M., 2009, "Acquired Von Willebrand Syndrome after Exchange of the Heartmate Xve to the Heartmate Ii Ventricular Assist Device," Eur. J. Cardiothorac. Surg., 35(6), pp. 1091-1093.
19. Alemu, Y., Girdhar, G., Xenos, M., Sheriff, J., Jesty, J., Einav, S., and Bluestein, D., 2010, "Design Optimization of a Mechanical Heart Valve for Reducing Valve Thrombogenicity-A Case Study With Ats Valve," ASAIO J., 56(5), pp. 389-396.
20. Bluestein, D., Einav, S., and Slepian, M. J., 2013, "Device Thrombogenicity Emulation: A Novel Methodology for Optimizing the Thromboresistance of Cardiovascular Devices," J. Biomech., 46(2), pp. 338-344.
21. Xenos, M., Girdhar, G., Alemu, Y., Jesty, J., Slepian, M., Einav, S., and Bluestein, D., 2010, "Device Thrombogenicity Emulator (Dte)-Design Optimization Methodology for Cardiovascular Devices: A Study in Two Bileaflet Mhv Designs," J. Biomech., 43(12), pp. 2400-2409.
22. Stern, D. R., Kazam, J., Edwards, P., Maybaum, S., Bello, R. A., D'alessandro, D. A., and Goldstein, D. J., 2010, "Increased Incidence of Gastrointestinal Bleeding Following Implantation of the Heartmate Ii Lvad," J. Card. Surg., 25(3), pp. 352-356.
23. Sponga, S., Nalli, C., Casonato, A., and Charbonneau, E., 2012, "Severe Upper Gastrointestinal Bleeding in Heartmate Ii Induced by Acquired Von Willebrand Deficiency: Anticoagulation Management," Ann. Thorac. Surg., 94(2), pp. e41-e43.
24. Park, S. J., Milano, C. A., Tatooles, A. J., Rogers, J. G., Adamson, R. M., Steidley, D. E., Ewald, G. A., Sundareswaran, K. S., Farrar, D. J., Slaughter, M. S., and Heartmate, I. I. C. I., 2012, "Outcomes in Advanced Heart Failure Patients With Left Ventricular Assist Devices for Destination Therapy," Circ. Heart Fail, 5(2), pp. 241-248.
25. Bluestein, D., Rambod, E., and Gharib, M., 2000, "Vortex Shedding as a Mechanism for Free Emboli Formation in Mechanical Heart Valves," ASME J. Biomech. Eng., 122(2), pp. 125-134. (Pubitemid 30318336)
26. Bludszuweit, C., 1995, "Three-Dimensional Numerical Prediction of Stress Loading of Blood Particles in a Centrifugal Pump," Artif. Organs, 19(7), pp. 590-596.
27. Bludszuweit, C., 1995, "Model for a General Mechanical Blood Damage Prediction," Artif. Organs, 19(7), pp. 583-589.
28. Arora, D., Behr, M., and Pasquali, M., 2004, "A Tensor-Based Measure for Estimating Blood Damage," Artif. Organs, 28(11), pp. 1002-1015. (Pubitemid 40378877)
29. Alemu, Y., and Bluestein, D., 2007, "Flow-Induced Platelet Activation and Damage Accumulation in a Mechanical Heart Valve: Numerical Studies," Artif. Organs, 31(9), pp. 677-688. (Pubitemid 47304377)
30. Capoccia, M., Bowles, C. T., Sabashnikov, A., and Simon, A., 2013, "Recurrent Early Thrombus Formation in Heartmate Ii Left Ventricular Assist Device" J. Investig. Med. High Impact Case Reports, 1(2), pp. 1-3.
31. Jesty, J., and Bluestein, D., 1999, "Acetylated Prothrombin as a Substrate in the Measurement of the Procoagulant Activity of Platelets: Elimination of the Feedback Activation of Platelets by Thrombin," Anal. Biochem., 272(1), pp. 64-70. (Pubitemid 29343383)