A behavioral comparison of the common laboratory rat strains Lister Hooded, Lewis, Fischer 344 and Wistar in an automated homecage system

Genes, Brain and Behavior

Volumn 13, Issue 3, 2014, Pages 305-321

  Clemens, L E ^a,b   Jansson, E K H ^a,b   Portal, E ^a,b   Riess, O ^a,b   Nguyen, H P ^a,b  

^a Institute of Medical Genetics and Applied Genomics   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Activity; Animal welfare; Automated homecage system; Exploratory behavior; Fischer 344; Lewis; Lister hooded; Metabolism; PhenoMaster; Rat strains; Social isolation; Standardization; Strain differences; Wistar

Indexed keywords

CARBON DIOXIDE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; BODY HEIGHT; BODY SIZE; BODY WEIGHT; CAGE; CIRCADIAN RHYTHM; COMPARATIVE STUDY; CONTROLLED STUDY; FISCHER 344 RAT; FLUID INTAKE; FOOD INTAKE; HABITUATION; HOMECAGE SYSTEM; LEWIS RAT; LIGHT DARK CYCLE; LISTER HOODED RAT; MALE; METABOLIC PARAMETERS; MOVEMENT (PHYSIOLOGY); NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RAT; RAT STRAIN; REARING; RESPIRATORY QUOTIENT; STRAIN DIFFERENCE; TIME SERIES ANALYSIS; WISTAR RAT;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

ACTIVITY; ANIMAL WELFARE; AUTOMATED HOMECAGE SYSTEM; EXPLORATORY BEHAVIOR; FISCHER 344; LEWIS; LISTER HOODED; METABOLISM; PHENOMASTER; RAT STRAINS; SOCIAL ISOLATION; STANDARDIZATION; STRAIN DIFFERENCES; WISTAR;

ANIMALS; AUTOMATION, LABORATORY; BEHAVIOR, ANIMAL; BODY WEIGHT; DRINKING; EATING; MOTOR ACTIVITY; PHENOTYPE; RATS; RATS, INBRED STRAINS; VIDEO RECORDING;

EID: 84896729266     PISSN: 16011848     EISSN: 1601183X     Source Type: Journal    
DOI: 10.1111/gbb.12093     Document Type: Article

References (46)

1. Berton, O., De, P.M., Chaouloff, F., Ramos, A. & Mormède, P. (1997) A multiple-test study of anxiety-related behaviours in six inbred rat strains. Behav Brain Res 85, 57-69.
2. Broersen, L.M. & Uylings, H.B.M. (1999) Visual attention task performance in Wistar and Lister Hooded rats: response inhibition deficits after medial prefrontal cortex lesions. Neuroscience 94, 47-57.
3. Brooks, S.P., Pask, T., Jones, L. & Dunnett, S.B. (2004) Behavioural profiles of inbred mouse strains used as transgenic backgrounds. I: motor tests. Genes. Brain Behav 3, 206-215.
4. Brooks, S.P., Pask, T., Jones, L. & Dunnett, S.B. (2005) Behavioural profiles of inbred mouse strains used as transgenic backgrounds. II: cognitive tests. Genes. Brain Behav 4, 307-317.
5. Chaouloff, F., Kulikov, A., Sarrieau, A., Castanon, N., Mormède, P. & De, P.M. (1995) Male Fischer 344 and Lewis rats display differences in locomotor reactivity, but not in anxiety-related behaviours: relationship with the hippocampal serotonergic system. Brain Res 693, 169-178.
6. Chesler, E.J., Wilson, S.G., Lariviere, W.R., Rodriguez-Zas, S.L. & Mogil, J.S. (2002) Identification and ranking of genetic and laboratory environment factors influencing a behavioral trait, thermal nociception, via computational analysis of a large data archive. Neurosci Biobehav Rev 26, 907-923.
7. Crabbe, J.C., Wahlsten, D. & Dudek, B.C. (1999) Genetics of mouse behavior: interactions with laboratory environment. Science 284, 1670-1672.
8. Daenen, E.W., Van der Heyden, J.A., Kruse, C.G., Wolterink, G. & Van Ree, J.M. (2001) Adaptation and habituation to an open field and responses to various stressful events in animals with neonatal lesions in the amygdala or ventral hippocampus. Brain Res 918, 153-165.
9. De Visser, L., Van den Bos, R., Kuurman, W.W., Kas, M.J.H. & Spruijt, B.M. (2006) Novel approach to the behavioural characterization of inbred mice: automated home cage observations. Genes Brain Behav 5, 458-466.
10. Dhabhar, F.S., Mcewen, B.S. & Spencer, R.L. (1993) Stress response, adrenal steroid receptor levels and corticosteroid-binding globulin levels--a comparison between Sprague-Dawley, Fischer 344 and Lewis rats. Brain Res 616, 89-98.
11. Eilam, D. (2003) Open-field behavior withstands drastic changes in arena size. Behav Brain Res 142, 53-62.
12. Fonio, E., Benjamini, Y. & Golani, I. (2012) Short and long term measures of anxiety exhibit opposite results. PLoS One 7, e48414.
13. Gil, M.C., Aguirre, J.A., Lemoine, A.P., Segura, E.T., Barontini, M. & Armando, I. (1999) Influence of age on stress responses to metabolic cage housing in rats. Cell Mol Neurobiol 19, 625-633.
14. Goulding, E.H., Schenk, A.K., Juneja, P., MacKay, A.W., Wade, J.M. & Tecott, L.H. (2008) A robust automated system elucidates mouse home cage behavioral structure. Proc Natl Acad Sci USA 30, 20575-20582.
15. Hall, F.S. (1998) Social deprivation of neonatal, adolescent, and adult rats has distinct neurochemical and behavioral consequences. Crit Rev Neurobiol 12, 129-162.
16. Hoy, J.B., Cody, B.A., Karlix, J.L., Schmidt, C.J., Tebbett, I.R., Toffollo, S., Van Haaren, F. & Wielbo, D. (1999) Pyridostigmine bromide alters locomotion and thigmotaxis of rats: gender effects. Pharmacol Biochem Behav 63, 401-406.
17. Hübener, J., Vauti, F., Funke, C., Wolburg, H., Ye, Y., Schmidt, T., Wolburg-Buchholz, K., Schmitt, I., Gardyan, A., Driessen, S., Arnold, H.H., Nguyen, H.P. & Riess, O. (2011) N-terminal ataxin-3 causes neurological symptoms with inclusions, endoplasmic reticulum stress and ribosomal dislocation. Brain 134, 1925-1942.
18. Izídio, G.S., Lopes, D.M., Spricigo, L. & Ramos, A. (2005) Common variations in the pretest environment influence genotypic comparisons in models of anxiety. Genes Brain Behav 4, 412-419.
19. Jhuang, H., Garrote, E., Mutch, J., Yu, X., Khilnani, V., Poggio, T., Steele, A.D. & Serre, T. (2010) Automated home-cage behavioural phenotyping of mice. Nat Commun 7, 1-68.
20. Kalliokoski, O., Jacobsen, K.R., Darusman, H.S., Henriksen, T., Weimann, A., Poulsen, H.E., Hau, J. & Abelson, K.S.P. (2013) Mice do not habituate to metabolism cage housing - a three week study of male BALB/c mice. PLoS One 8, e58460.
21. Kas, M.J. & van Ree, J.M. (2004) Dissecting complex behaviours in the post-genomic era. Trends Neurosci 27, 366-369.
22. Lipp, H., Litvin, O., Galsworthy, M., Vyssotski, D.L., Vyssotski, A.L., Zinn, P. & Rau, A.E. (2005) Automated behavioral analysis of mice using INTELLICAGE: inter-laboratory comparisons and validation with exploratory behavior and spatial learning. In Noldus, L.P.J.J., Grieco, F., Loijens, L.W.S. & Zimmerman, H.P. (eds), Proceedings of Measuring Behavior 2005. Fifth International Conference on Methods and Techniques in Behavioral Research. Noldus Information Technology, Wageningen, Netherlands, pp. 66-69.
23. Lukkes, J.L., Watt, M.J., Lowry, C.A. & Forster, G.L. (2009) Consequences of post-weaning social isolation on anxiety behavior and related neural circuits in rodents. Front Behav Neurosci 3, 18.
24. Mandillo, S., Tucci, V., Hölter, S.M. et al. (2008) Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory study. Physiol Genomics 34, 243-255.
25. McDermott, C. & Kelly, J.P. (2008) Comparison of the behavioural pharmacology of the Lister-Hooded with 2 commonly utilised albino rat strains. Prog Neuropsychopharmacol Biol Psychiatry 32, 1816-1823.
26. Onaivi, E.S., Maguire, P.A., Tsai, N.F., Davies, M.F. & Loew, G.H. (1992) Comparison of behavioral and central BDZ binding profile in three rat lines. Pharmacol Biochem Behav 43, 825-831.
27. Ossenkopp, K.-P., Sorenson, L. & Mazmanian, D.S. (1994) Factor analysis of open-field behavior in the rat (Rattus norvegicus): application of the three-way PARAFAC model to a longitudinal data set. Behav Process 31, 129-144.
28. Painsipp, E., Wultsch, T., Edelsbrunner, M.E., Tasan, R.O., Singewald, N., Herzog, H. & Holzer, P. (2008) Reduced anxiety-like and depression-related behavior in neuropeptide Y Y4 receptor knockout mice. Genes Brain Behav 7, 532-542.
29. Ramos, A., Berton, O., Mormède, P. & Chaouloff, F. (1997) A multiple-test study of anxiety-related behaviours in six inbred rat strains. Behav Brain Res 85, 57-69.
30. Rex, A., Sondern, U., Voigt, J.P., Franck, S. & Fink, H. (1996) Strain differences in fear-motivated behavior of rats. Pharmacol Biochem Behav 54, 107-111.
31. Richards, J.B., Lloyd, D.R., Kuehlewind, B., Militello, L., Paredez, M., Solberg Woods, L. & Palmer, A.A. (2013) Strong genetic influence on measures of behavioral-regulation among inbred rat strains. Genes Brain Behav 12, 490-502.
32. Russell, P.A. & Williams, D.I. (1973) Effects of repeated testing on rats' locomotor activity in the open-field. Anim Behav 21, 109-111.
33. Simon, P., Dupuis, R. & Costentin, J. (1994) Thigmotaxis as an index of anxiety in mice. Influence of dopaminergic transmissions. Behav Brain Res 61, 59-64.
34. Tecott, L.H. & Nestler, E.J. (2004) Neurobehavioral assessment in the information age. Nat Neurosci 7, 462-466.
35. Thiel, C.M., Müller, C.P., Huston, J.P. & Schwarting, R.K. (1999) High versus low reactivity to a novel environment: behavioural, pharmacological and neurochemical assessments. Neuroscience 93, 243-251.
36. Tucci, V., Lad, H.V., Parker, A., Polley, S., Brown, S.D.M. & Nolan, P.M. (2006) Gene-environment interactions differentially affect mouse strain behavioral parameters. Mamm Genome 17, 1113-1120.
37. Van der Staay, F.J. & Steckler, T. (2002) The fallacy of behavioral phenotyping without standardisation. Genes Brain Behav 1, 9-13.
38. Van der Staay, F.J., Blokland, A. & Ring, N. (1996) Behavioral differences between outbred Wistar, inbred Fischer 344, brown Norway, and hybrid Fischer 344 x brown Norway rats. Physiol Behav 60, 97-109.
39. Van der Staay, F.J., Schuurman, T., Van Reenen, C.G. & Korte, S.M. (2009) Emotional reactivity and cognitive performance in aversively motivated tasks: a comparison between four rat strains. Behav Brain Funct 5, 50.
40. Voikar, V., Colacicco, G., Gruber, O., Vannoni, E., Lipp, H.-P. & Wolfer, D.P. (2010) Conditioned response suppression in the IntelliCage: assessment of mouse strain differences and effects of hippocampal and striatal lesions on acquisition and retention of memory. Behav Brain Res 213, 304-312.
41. Vyssotski, Alexei L., Omo, G.D., Poletaeva, I.I., Vyssotski, Dmitri L., Minichiello, L., Wolfer, D.P., Lipp, H.-P., Dell'Omo, G., Vyssotski, D.L. & Klein, R. (2002) Long-term monitoring of hippocampus-dependent behavior in naturalistic settings: mutant mice lacking neurotrophin receptor TrkB in the forebrain show spatial learning but impaired behavioral flexibility. Hippocampus 12, 27-38.
42. Wahlsten, D., Metten, P., Phillips, T.J. et al. (2003a) Different data from different labs: lessons from studies of gene-environment interaction. J Neurobiol 54, 283-311.
43. Wahlsten, D., Rustay, N.R., Metten, P. & Crabbe, John C. (2003b) In search of a better mouse test. Trends Neurosci 26, 132-136.
44. Weiss, I.C., Di Iorio, L., Feldon, J., Domeney, A.M., Di, L. & Annette, M. (2000) Strain differences in the isolation-induced effects on prepulse inhibition of the acoustic startle response and on locomotor activity. Behav Neurosci 114, 364-373.
45. Wilhelm, C.J. & Mitchell, S.H. (2009) Strain differences in delay discounting using inbred rats. Genes Brain Behav 8, 426-434.
46. Zarringhalam, K., Ka, M., Kook, Y.-H., Terranova, J.I., Suh, Y., King, O.D. & Um, M. (2012) An open system for automatic home-cage behavioral analysis and its application to male and female mouse models of Huntington's disease. Behav Brain Res 229, 216-225.