Immunization using GroEL decreases Clostridium difficile intestinal colonization

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Péchiné, Séverine ^a   Hennequin, Claire ^b   Boursier, Céline ^a   Hoys, Sandra ^a   Collignon, Anne ^a  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b UNIVERSITÉ CLERMONT AUVERGNE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONIN 60; PROTEIN ANTIBODY;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL STRAIN; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM DIFFICILE INFECTION; CONTROLLED STUDY; FEMALE; HAMSTER; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOBLOTTING; MOUSE; NONHUMAN; PROTECTION; PROTEIN ANALYSIS; PROTEOMICS; TWO DIMENSIONAL GEL ELECTROPHORESIS;

ANIMALS; ANTIBODIES, BACTERIAL; ANTIBODY SPECIFICITY; BACTERIAL PROTEINS; BACTERIAL VACCINES; CELL WALL; CHAPERONIN 60; CLOSTRIDIUM DIFFICILE; CRICETINAE; DISEASE MODELS, ANIMAL; ENTEROCOLITIS, PSEUDOMEMBRANOUS; FEMALE; IMMUNIZATION; INTESTINES; MICE; PROTEOMICS; RECOMBINANT PROTEINS;

EID: 84896729137     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0081112     Document Type: Article

References (37)

1. Kelly CP, LaMont JT (1998) Clostridium difficile infection. Annu Rev Med 49: 375-390.
2. Bartlett JG (1990) Clostridium difficile: clinical considerations. Rev Infect Dis 12 Suppl 2: S243-251.
3. Rupnik M, Wilcox MH, Gerding DN (2009) Clostridium difficile infection: new developments in epidemiology and pathogenesis. Nat Rev Microbiol 7: 526-536.
4. McFarland LV, Mulligan ME, Kwok RY, Stamm WE (1989) Nosocomial acquisition of Clostridium difficile infection. N Engl J Med 320: 204-210.
5. Kyne L, Warny M, Qamar A, Kelly CP (2001) Association between antibody response to toxin A and protection against recurrent Clostridium difficile diarrhoea. Lancet 357: 189-193.
6. Sougioultzis S, Kyne L, Drudy D, Keates S, Maroo S, et al. (2005) Clostridium difficile toxoid vaccine in recurrent C. difficile-associated diarrhea. Gastroenterology 128: 764-770.
7. Wright A, Wait R, Begum S, Crossett B, Nagy J, et al. (2005) Proteomic analysis of cell surface proteins from Clostridium difficile . Proteomics 5: 2443-2452.
8. Calabi E, Calabi F, Phillips AD, Fairweather NF (2002) Binding of Clostridium difficile surface layer proteins to gastrointestinal tissues. Infect Immun 70: 5770-5778.
9. Drudy D, O'Donoghue DP, Baird A, Fenelon L, O'Farrelly C (2001) Flow cytometric analysis of Clostridium difficile adherence to human intestinal epithelial cells. J Med Microbiol 50: 526-534.
10. Cerquetti M, Serafino A, Sebastianelli A, Mastrantonio P (2002) Binding of Clostridium difficile to Caco-2 epithelial cell line and to extracellular matrix proteins. FEMS Immunol Med Microbiol 32: 211-218.
11. O'Brien JB, McCabe MS, Athie-Morales V, McDonald GS, Ni Eidhin DB, et al. (2005) Passive immunisation of hamsters against Clostridium difficile infection using antibodies to surface layer proteins. FEMS Microbiol Lett 246: 199-205.
12. Ni Eidhin DB, O'Brien JB, McCabe MS, Athie-Morales V, Kelleher DP (2008) Active immunization of hamsters against Clostridium difficile infection using surface-layer protein. FEMS Immunol Med Microbiol 52: 207-218.
13. Pechine S, Janoir C, Boureau H, Gleizes A, Tsapis N, et al. (2007) Diminished intestinal colonization by Clostridium difficile and immune response in mice after mucosal immunization with surface proteins of Clostridium difficile. Vaccine 25: 3946-3954.
14. Wexler H, Mulligan ME, Finegold SM (1984) Polyacrylamide gel electrophoresis patterns produced by Clostridium difficile. Rev Infect Dis 6 Suppl 1: S229-234.
15. Hennequin C, Porcheray F, Waligora-Dupriet A, Collignon A, Barc M, et al. (2001) GroEL (Hsp60) of Clostridium difficile is involved in cell adherence. Microbiology 147: 87-96.
16. Sandolo C, Pechine S, Le Monnier A, Hoys S, Janoir C, et al. (2011) Encapsulation of Cwp84 into pectin beads for oral vaccination against Clostridium difficile. Eur J Pharm Biopharm 79: 566-573.
17. Lawley TD, Clare S, Walker AW, Goulding D, Stabler RA, et al. (2009) Antibiotic treatment of clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts. Infect Immun 77: 3661-3669.
18. Froidevaux-Klipfel L, Poirier F, Boursier C, Crepin R, Pous C, et al. (2011) Modulation of septin and molecular motor recruitment in the microtubule environment of the Taxol-resistant human breast cancer cell line MDA-MB-231. Proteomics 11: 3877-3886.
19. Pechine S, Janoir C, Collignon A (2005) Variability of Clostridium difficile surface proteins and specific serum antibody response in patients with Clostridium difficile-associated disease. J Clin Microbiol 43: 5018-5025.
20. Pechine S, Deneve C, Le Monnier A, Hoys S, Janoir C, et al. (2011) Immunization of hamsters against Clostridium difficile infection using the Cwp84 protease as an antigen. FEMS Immunol Med Microbiol 63: 73-81.
21. Tsuzuki T, Ina K, Ohta M, Hasegawa T, Nagasaka T, et al. (2002) Clarithromycin increases the release of heat shock protein B from Helicobacter pylori. Aliment Pharmacol Ther 16 Suppl 2: 217-228.
22. Frisk A, Ison CA, Lagergard T (1998) GroEL heat shock protein of Haemophilus ducreyi: association with cell surface and capacity to bind to eukaryotic cells. Infect Immun 66: 1252-1257.
23. Kaufmann SH (1990) Heat shock proteins and the immune response. Immunol Today 11: 129-136.
24. Young RA, Elliott TJ (1989) Stress proteins, infection, and immune surveillance. Cell 59: 5-8.
25. Ferrero RL, Thiberge JM, Kansau I, Wuscher N, Huerre M, et al. (1995) The GroES homolog of Helicobacter pylori confers protective immunity against mucosal infection in mice. Proc Natl Acad Sci U S A 92: 6499-6503.
26. Gomez FJ, Allendoerfer R, Deepe GS, Jr. (1995) Vaccination with recombinant heat shock protein 60 from Histoplasma capsulatum protects mice against pulmonary histoplasmosis. Infect Immun 63: 2587-2595.
27. van Eden W, van der Zee R, Prakken B (2005) Heat-shock proteins induce Tcell regulation of chronic inflammation. Nat Rev Immunol 5: 318-330.
28. Zugel U, Kaufmann SH (1999) Role of heat shock proteins in protection from and pathogenesis of infectious diseases. Clin Microbiol Rev 12: 19-39.
29. Detanico T, Rodrigues L, Sabritto AC, Keisermann M, Bauer ME, et al. (2004) Mycobacterial heat shock protein 70 induces interleukin-10 production: immunomodulation of synovial cell cytokine profile and dendritic cell maturation. Clin Exp Immunol 135: 336-342.
30. van Eden W, Koets A, van Kooten P, Prakken B, van der Zee R (2003) Immunopotentiating heat shock proteins: negotiators between innate danger and control of autoimmunity. Vaccine 21: 897-901.
31. Quintana FJ, Carmi P, Mor F, Cohen IR (2003) DNA fragments of the human 60-kDa heat shock protein (HSP60) vaccinate against adjuvant arthritis: identification of a regulatory HSP60 peptide. J Immunol 171: 3533-3541.
32. Quintana FJ, Carmi P, Cohen IR (2002) DNA vaccination with heat shock protein 60 inhibits cyclophosphamide-accelerated diabetes. J Immunol 169: 6030-6035.
33. Khan MN, Shukla D, Bansal A, Mustoori S, Ilavazhagan G (2009) Immunogenicity and protective efficacy of GroEL (hsp60) of Streptococcus pneumoniae against lethal infection in mice. FEMS Immunol Med Microbiol 56: 56-62.
34. Paliwal PK, Bansal A, Sagi SS, Mustoori S, Govindaswamy I (2008) Cloning, expression and characterization of heat shock protein 60 (groEL) of Salmonella enterica serovar Typhi and its role in protective immunity against lethal Salmonella infection in mice. Clin Immunol 126: 89-96.
35. Sinha K, Bhatnagar R (2010) GroEL provides protection against Bacillus anthracis infection in BALB/c mice. Mol Immunol 48: 264-271.
36. Forrest BD, Shearman DJ, LaBrooy JT (1990) Specific immune response in humans following rectal delivery of live typhoid vaccine. Vaccine 8: 209-212.
37. Kantele A, Hakkinen M, Moldoveanu Z, Lu A, Savilahti E, et al. (1998) Differences in immune responses induced by oral and rectal immunizations with Salmonella typhi Ty21a: evidence for compartmentalization within the common mucosal immune system in humans. Infect Immun 66: 5630-5635.