Acute lymphoblastic leukemia developing in a patient with noonan syndrome harboring a PTPN11 germline mutation

Journal of Pediatric Hematology/Oncology

Volumn 36, Issue 2, 2014, Pages

  Sakamoto, Kenichi ^a   Imamura, Toshihiko ^a   Asai, Daisuke ^a   Goto Kawashima, Sachiko ^a   Yoshida, Hideki ^a   Fujiki, Atsushi ^a   Furutani, Akiyo ^b   Ishida, Hiroyuki ^a   Aoki, Yoko ^c   Hosoi, Hajime ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b KYOTO SECOND RED CROSS HOSPITAL   (Japan)

^c TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

acute lymphoblastic leukemia; hyperdiploid karyotype; Noonan syndrome; PTPN11; RAS MAPK syndromes

Indexed keywords

ASPARAGINASE; CYCLOPHOSPHAMIDE; CYTARABINE; DEXAMETHASONE; GENOMIC DNA; K RAS PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PIRARUBICIN; PREDNISOLONE; PROTEIN TYROSINE PHOSPHATASE SHP 2; RAF PROTEIN; VINCRISTINE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; BLOOD ANALYSIS; BONE MARROW BIOPSY; CANCER REGRESSION; CASE REPORT; CHILD; CHROMOSOME G BAND; DIPLOIDY; DNA EXTRACTION; DOWNWARD PALPEBRAL SLANT; EXON; FEMALE; FEVER; FLUORESCENCE IN SITU HYBRIDIZATION; GENE; GENE MUTATION; GERM LINE; HEART ATRIUM SEPTUM DEFECT; HEPATOMEGALY; HUMAN; HYPERTELORISM; IMMUNOPHENOTYPING; JAPANESE; KARYOTYPE; LEUKEMOGENESIS; MISSENSE MUTATION; MUTATIONAL ANALYSIS; NOONAN SYNDROME; ONCOGENE K RAS; PALLOR; PHYSICAL EXAMINATION; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PRIORITY JOURNAL; PTPN11 GENE; RAF1 GENE; SHOC2 GENE; SHORT STATURE; TETRASOMY;

ABNORMAL KARYOTYPE; CHILD; DNA MUTATIONAL ANALYSIS; FEMALE; GERM-LINE MUTATION; HUMANS; NOONAN SYNDROME; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11;

EID: 84896722673     PISSN: 10774114     EISSN: 15363678     Source Type: Journal    
DOI: 10.1097/MPH.0000000000000002     Document Type: Article

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