A mannosylated cell-penetrating peptide-graft-polyethylenimine as a gene delivery vector

Biomaterials

Volumn 35, Issue 13, 2014, Pages 4236-4246

  Hu, Ying ^a,b   Xu, Beihua ^b   Ji, Qixiong ^b   Shou, Dan ^c   Sun, Xiaoyi ^d   Xu, Jiaojiao ^b,e   Gao, Jianqing ^a   Liang, Wenquan ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b Zhejiang Pharmaceutical College   (China)

^c Institute of TCM Literature and Information   (China)

^d ZHEJIANG UNIVERSITY CITY COLLEGE   (China)

^e WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

APCs targeted gene delivery vector; Cell penetrating peptides (CPPs); Mannose; Polyethylenimine (PEI)

Indexed keywords

CYTOLOGY; EFFICIENCY; GENE THERAPY; GENE TRANSFER; MOLECULAR WEIGHT; PEPTIDES; VECTORS; VIRUSES;

ANTIGEN PRESENTING CELLS; CELL PENETRATING PEPTIDES (CPPS); CELL-PENETRATING PEPTIDE; MANNOSE; POLYETHYLENIMINES; SPHERICAL NANOPARTICLES; TARGETED GENE DELIVERY; TRANSFECTION EFFICIENCY;

MOLECULAR BIOLOGY;

CELL PENETRATING PEPTIDE; MANNOSE; MANNOSE RECEPTOR; PLASMID DNA; POLYETHYLENEIMINE;

ANIMAL EXPERIMENT; ANTIGEN PRESENTING CELL; ARTICLE; CELL VIABILITY; CELLULAR DISTRIBUTION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DRUG CYTOTOXICITY; FEMALE; FLOW CYTOMETRY; GENE DELIVERY SYSTEM; GENE TARGETING; GENE VECTOR; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INFRARED SPECTROSCOPY; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SPLEEN CELL; ZETA POTENTIAL; ANIMAL; BAGG ALBINO MOUSE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; GENE TRANSFER; HELA CELL LINE;

ANIMALS; CELL SURVIVAL; CELL-PENETRATING PEPTIDES; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HELA CELLS; HUMANS; MICE; MICE, INBRED BALB C; POLYETHYLENEIMINE;

EID: 84896708168     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.01.065     Document Type: Article

References (35)

1. O'Connor T.P., Crystal R.G. Genetic medicines: treatment strategies for hereditary disorders. Nat Rev Genet 2006, 7:261-276.
2. Kim D.H., Rossi J.J. Strategies for silencing human disease using RNA interference. Nat Rev Genet 2007, 8:173-184.
3. Pan S., Cao D., Yi W., Huang H., Feng M. Abiodegradable and serum-resistant gene delivery carrier composed of polyamidoamine-poly N,N'-di-(2-aminoethyl) aminoethyl glutamine copolymer. Colloids Surf B Biointerfaces 2013, 104:294-302.
4. Kim T.I., Lee M., Kim S.W. Aguanidinylated bioreducible polymer with high nuclear localization ability for gene delivery systems. Biomaterials 2010, 31:1798-1804.
5. Song H.P., Yang J.Y., Lo S.L., Wang Y., Fan W.M., Tang X.S., et al. Gene transfer using self-assembled ternary complexes of cationic magnetic nanoparticles, plasmid DNA and cell-penetrating Tat peptide. Biomaterials 2010, 31:769-778.
6. Boussif O., Lezoualc'h F., Zanta M.A., Mergny M.D., Scherman D., Demeneix B., et al. Aversatile vector for gene and oligonucleotide transfer into cells in culture and invivo: polyethylenimine. Proc Natl Acad Sci U S A 1995, 92(16):7297-7301.
7. Schäfer J., Höbel S., Bakowsky U., Aigner A. Liposome-polyethylenimine complexes for enhanced DNA and siRNA delivery. Biomaterials 2010, 31:6892-6900.
8. Lungwitz U., Breunig M., Blunk T., Göpferich A. Polyethylenimine-based non-viral gene delivery systems. Eur J Pharm Biopharm 2005, 60:247-266.
9. Itaka K., Harada A., Yamasaki Y., Nakamura K., Kawaguchi H., Kataoka K. In situ single cell observation by fluorescence resonance energy transfer reveals fast intra-cytoplasmic delivery and easy release of plasmid DNA complexed with linear polyethylenimine. JGene Med 2004, 6:76-84.
10. Deng R., Yue Y., Jin F., Chen Y., Kung H.F., Lin M.C., et al. Revisit the complexation of PEI and DNA-how to make low cytotoxic and highly efficient PEI gene transfection non-viral vectors with a controllable chain length and structure?. JControl Release 2009, 140:40-46.
11. Merkel O.M., Librizzi D., Pfestroff A., Schurrat T., Buyens K., Sanders N.N., et al. Stability of siRNA polyplexes from poly(ethylenimine) and poly(ethylenimine)-g-poly(ethylene glycol) under invivo conditions: effects on pharmacokinetics and biodistribution measured by Fluorescence Fluctuation Spectroscopy and Single Photon Emission Computed Tomography (SPECT) imaging. JControl Release 2009, 138:148-159.
12. Mao S., Neu M., Germershaus O., Merkel O., Sitterberg J., Bakowsky U., et al. Infl{ligature}uence of polyethylene glycol chain length on the physicochemical and biological properties of poly(ethyleneimine)-graft-poly(ethylene glycol)blockcopolymer/SiRNA polyplexes. Bioconjug Chem 2006, 17:1209-1218.
13. Biswal B.K., Debata N.B., Verma R.S. Development of a targeted siRNA delivery system using FOL-PEG-PEI conjugate. Mol Biol Rep 2010, 37:2919-2926.
14. Kang J.H., Tachibana Y., Kamata W., Mahara A., Harada-Shiba M., Yamaoka T. Liver-targeted siRNA delivery by polyethylenimine (PEI)-pullulan carrier. Bioorg Med Chem 2010, 18:3946-3950.
15. Chen Y.J., Liu B.R., Dai Y.H., Lee C.Y., Chan M.H., Chen H.H., et al. Agene delivery system for insect cells mediated by arginine-rich cell-penetrating peptides. Gene 2012, 493:201-210.
16. Bolhassani A. Potential efficacy of cell-penetrating peptides for nucleic acid and drug delivery in cancer. Biochim Biophys Acta 2011, 1816:232-246.
17. Hamano N., Negishi Y., Fujisawa A., Manandhar M., Sato H., Katagiri F., et al. Modification of the C16Y peptide on nanoparticles is an effective approach to target endothelial and cancer cells via the integrin receptor. Int J Pharm 2012, 428:114-117.
18. Diebold S.S., Kursa M., Wagner E., Cotten M., Zenke M. Mannose polyethylenimine conjugates for targeted DNA delivery into dendritic cells. JBiol Chem 1999, 274:19087-19094.
19. Park I.Y., Kim I.Y., Yoo M.K., Choi Y.J., Cho M.H., Cho C.S. Mannosylated polyethylenimine coupled mesoporous silica nanoparticles for receptor-mediated gene delivery. Int J Pharm 2008, 359:280-287.
20. Chen Y.Z., Ruan G.X., Yao X.L., Li L.M., Hu Y., Tabata Y., et al. Co-transfection gene delivery of dendritic cells induced effective lymph node targeting and anti-tumor vaccination. Pharm Res 2013, 30:1502-1512.
21. Chen Y.Z., Yao X.L., Ruan G.X., Zhao Q.Q., Tang G.P., Tabata Y., et al. Gene-carried chitosan-linked polyethylenimine induced high gene transfection efficiency on dendritic cells. Biotechnol Appl Biochem 2012, 59:346-352.
22. Ding Z., Verbaan F.J., Bivas-Benita M., Bungener L., Huckriede A., van den Berg D.J., et al. Microneedle arrays for the transcutaneous immunization of diphtheria and influenza in BALB/c mice. JControl Release 2009, 136:71-78.
23. Wei H., Wang S., Zhang D., Hou S., Qian W., Li B., et al. Targeted delivery of tumor antigens to activated dendritic cells via CD11c molecules induces potent antitumor immunity in mice. Clin Cancer Res 2009, 15:4612-4621.
24. Jiang H.L., Kim Y.K., Arote R., Jere D., Quan J.S., Yu J.H., et al. Mannosylated chitosan-graft-polyethylenimine as a gene carrier for Raw 264.7 cell targeting. Int J Pharm 2009, 375:133-139.
25. Lai W.F., Tang G.P., Wang X., Li G., Yao H., Shen Z., et al. Cyclodextrin-pei-tat polymer as a vector for plasmid DNA delivery to Placenta Mesenchymal stem cells. Bionanoscience 2011, 1:89-96.
26. Guy J., Drabek D., Antoniou M. Delivery of DNA into mammalian cells by receptor-mediated endocytosis and gene therapy. Mol Biotechnol 1995, 3:237-248.
27. Nomura T., Nakjima S., Kawabata K., Yamashita F., Takakura Y., Hashida M. Intratumoral pharmacokinetics and invivo gene expression of naked plasmid DNA and its cationic liposome complexes after direct gene-transfer. Cancer Res 1997, 57:2681-2686.
28. Hee Ahn Hyun, Suk Lee Min, Hee Cho Mi, Na Shin Yu, Hwa Lee Jung, Sook Kim Kyung, et al. DNA/PEI nano-particles for gene delivery of rat bone marrow stem cells. Colloids Surfaces Physicochem Eng Aspects 2008, 313-314:116-120.
29. Liang W., Gong H., Yin D., Lu S., Fu Q. High-molecular-weight polyethyleneimine conjuncted pluronic for gene transfer agents. Chem Pharm Bull (Tokyo) 2011, 59:1094-1101.
30. Sun X., Chen S., Han J., Zhang Z. Mannosylated biodegradable polyethyleneimine for targeted DNA delivery to dendritic cells. Int J Nanomedicine 2012, 7:2929-2942.
31. Sahay G., Alakhova D.Y., Kabanov A.V. Endocytosis of nanomedicines. JControl Release 2010, 145(3):182-195.
32. Isaji K., Kawase A., Matono M., Guan X., Nishikawa M., Takakura Y. Enhanced CTL response by controlled intracellular trafficking of antigen in dendritic cells following DNA vaccination. JControl Release 2009, 135:227-233.
33. Mendoza L., Olaso E., Anasagasti M.J., Fuentes A.M., Vidal-Vanaclocha F. Mannose receptor-mediated endothelial cell activation contributes to HELA melanoma cell adhesion and metastasis in liver. JCell Physiol 1998, 174:322-330.
34. Mikszta J.A., Alarcon J.B., Brittingham J.M., Sutter D.E., Pettis R.J., Harvey N.G. Improved genetic immunization via micromechanical disruption of skin-barrier function and targeted epidermal delivery. Nat Med 2002, 8:415-419.
35. Laurent P.E., Bonnet S., Alchas P., Regolini P., Mikszta J.A., Pettis R., et al. Evaluation of the clinical performance of a new intradermal vaccine administration technique and associated delivery system. Vaccine 2007, 25:8833-8842.