A guanidinylated bioreducible polymer with high nuclear localization ability for gene delivery systems

Biomaterials

Volumn 31, Issue 7, 2010, Pages 1798-1804

  Kim, Tae il ^a   Lee, Minhyung ^b   Kim, Sung Wan ^a,b  

^a UNIVERSITY OF UTAH   (United States)

^b Hanyang University   (South Korea)

Author keywords

Bioreducible polymer; Cytotoxicity; Gene transfer; Guanidinylation; Nuclear localization ability

Indexed keywords

AGAROSE GEL ELECTROPHORESIS; BIOREDUCIBLE POLYMER; CELLULAR UPTAKE EFFICIENCY; GENE DELIVERY SYSTEMS; MAMMALIAN CELL LINES; NUCLEAR LOCALIZATION; POLYPLEXES; POSITIVELY CHARGED; REDUCING CONDITIONS; STRUCTURAL ADVANTAGE; TRANSFECTION EFFICIENCY; WEIGHT RATIOS;

BIODEGRADATION; CELL CULTURE; ELECTROPHORESIS; MAMMALS; NUCLEIC ACIDS;

GENE TRANSFER;

CELL PENETRATING PEPTIDE; GUANIDINE; GUANIDINYLATED BIOREDUCIBLE POLYMER; NANOPARTICLE; PLASMID DNA; POLY(CYSTAMINEBISACRYLAMIDE DIAMINOHEXANE); POLYMER; UNCLASSIFIED DRUG;

AGAR GEL ELECTROPHORESIS; ANIMAL CELL; ARTICLE; BIODEGRADABILITY; CELL NUCLEUS; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; IN VITRO GENE TRANSFER; INTERNALIZATION; INTRACELLULAR TRANSPORT; MOLECULAR SIZE; MOLECULAR WEIGHT; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; ZETA POTENTIAL;

ANIMALS; BIOCOMPATIBLE MATERIALS; BIOLOGICAL ASSAY; BIOLOGICAL TRANSPORT; CELL DEATH; CELL LINE; CELL NUCLEUS; ELECTROPHORESIS, AGAR GEL; FLOW CYTOMETRY; GENE TRANSFER TECHNIQUES; GUANIDINE; HUMANS; INTRACELLULAR SPACE; MICE; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, TRANSMISSION; PARTICLE SIZE; POLYMERS; TRANSFECTION;

MAMMALIA;

EID: 73249136229     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.10.034     Document Type: Article

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