Pyruvate administration reduces recurrent/moderate hypoglycemia-induced cortical neuron death in diabetic rats

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Choi, Bo Young ^a   Kim, Jin Hee ^a   Kim, Hyun Jung ^a   Yoo, Jin Hyuk ^a   Song, Hong Ki ^a   Sohn, Min ^b   Won, Seok Joon ^c   Suh, Sang Won ^a  

^a Hallym University   (South Korea)

^b Inha University   (South Korea)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PYRUVIC ACID; STREPTOZOCIN; ZINC; GLUTATHIONE; NEUROPROTECTIVE AGENT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;

ADJUVANT THERAPY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BRAIN CORTEX; CELL ACTIVATION; CONTROLLED STUDY; DISEASE SEVERITY; DRUG HALF LIFE; ENZYME ACTIVATION; HYPOGLYCEMIA; MALE; MICROGLIA; MONOTHERAPY; NERVE CELL NECROSIS; NONHUMAN; OXIDATIVE STRESS; RAT; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; ANIMAL; CELL DEATH; DENDRITE; DISEASE MODEL; DRUG EFFECTS; EXPERIMENTAL DIABETES MELLITUS; INSULIN DEPENDENT DIABETES MELLITUS; METABOLISM; NERVE CELL; PATHOLOGY; VASCULARIZATION;

ANIMALS; CELL DEATH; CEREBRAL CORTEX; DENDRITES; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; DISEASE MODELS, ANIMAL; GLUTATHIONE; HYPOGLYCEMIA; MALE; MICROGLIA; NEURONS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; POLY(ADP-RIBOSE) POLYMERASES; PYRUVIC ACID; RATS; ZINC;

EID: 84896703569     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0081523     Document Type: Article

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