Hevin plays a pivotal role in corneal wound healing

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Chaurasia, Shyam S ^a,b,c   Perera, Promoda R ^a   Poh, Rebekah ^a   Lim, Rayne R ^a   Wong, Tina T ^a,d,e   Mehta, Jodhbir S ^a,b,d  

^a SINGAPORE EYE RESEARCH INSTITUTE   (Singapore)

^b DUKE NUS MEDICAL SCHOOL   (Singapore)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d SINGAPORE NATIONAL EYE CENTRE   (Singapore)

^e NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 4; HEVIN; MATRIX METALLOPROTEINASE; SCLEROPROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CHRONIC INFLAMMATION; CONTROLLED STUDY; CORNEA CELL; CORNEA INJURY; CORNEA NEOVASCULARIZATION; CORNEA STROMA; CORNEAL HAZE; FIBROSIS; KERATECTOMY; KERATITIS; MOUSE; MYOFIBROBLAST; NONHUMAN; OPHTHALMIC EXCIMER LASER; PROTEIN EXPRESSION; UPREGULATION; WOUND HEALING;

ANIMALS; APOPTOSIS; CALCIUM-BINDING PROTEINS; CORNEA; CORNEAL STROMA; EXTRACELLULAR MATRIX PROTEINS; FIBROBLASTS; FIBROSIS; GENE EXPRESSION; IN SITU NICK-END LABELING; INFLAMMATION; MICE; MICE, KNOCKOUT; NEOVASCULARIZATION, PATHOLOGIC; WOUND HEALING;

EID: 84896702673     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0081544     Document Type: Article

References (53)

1. Wilson SE, Mohan RR, Mohan RR, Ambrósio R Jr, Hong J et al. (2001) The corneal wound healing response: cytokine-mediated interaction of the epithelium, stroma, and inflammatory cells. Prog Retin Eye Res 20: 625-637. doi:10.1016/S1350-9462(01)00008-8. PubMed: 11470453. (Pubitemid 32695343)
2. Jester JV, Petroll WM, Cavanagh HD (1999) Corneal stromal wound healing in refractive surgery: the role of myofibroblasts. Prog Retin Eye Res 18: 311-356. doi:10.1016/S1350-9462(98)00021-4. PubMed: 10192516. (Pubitemid 29092610)
3. Nishida T, Tanaka T (1996) Extracellular matrix and growth factors in corneal wound healing. Curr Opin Ophthalmol 7: 2-11. doi:10.1097/00055735- 199608000-00002. PubMed: 10163634. (Pubitemid 26396537)
4. Kuo IC (2004) Corneal wound healing. Curr Opin Ophthalmol 15: 311-315. doi:10.1097/00055735-200408000-00006. PubMed: 15232470.
5. Gabison EE, Huet E, Baudouin C, Menashi S (2009) Direct epithelial-stromal interaction in corneal wound healing: Role of EMMPRIN/CD147 in MMPs induction and beyond. Prog Retin Eye Res 28: 19-33. doi:10.1016/j. preteyeres.2008.11.001. PubMed: 19056510.
6. Jester JV, Barry-Lane PA, Cavanagh HD, Petroll WM (1996) Induction of alpha-smooth muscle actin expression and myofibroblast transformation in cultured corneal keratocytes. Cornea 15: 505-516. PubMed: 8862928. (Pubitemid 26271790)
7. Beales MP, Funderburgh JL, Jester JV, Hassell JR (1999) Proteoglycan synthesis by bovine keratocytes and corneal fibroblasts: Maintenance of the keratocyte phenotype in culture. Invest Ophthalmol Vis Sci 40: 1658-1663. PubMed: 10393032. (Pubitemid 29297138)
8. Jester JV, Petroll M, Cavanagh D (1999) Corneal stromal wound healing in refractive surgery: the role of myofibroblasts. Prog Retin Eye Res 18: 311-356. doi:10.1016/S1350-9462(98)00021-4. PubMed: 10192516. (Pubitemid 29092610)
9. Tomasek JJ, Gabbiani G, Hinz B, Chaponnier C, Brown RA (2002) Myofibroblast and mechanoregulation of connective tissue remodelling. Nature Rev Mol Cell Biol 3: 349-363. doi:10.1038/nrm809. (Pubitemid 34619269)
10. Hinz B (2007) Formation and function of the myofibroblast during tissue repair. J Invest Dermatol 127: 526-537. doi:10.1038/sj.jid.5700613. PubMed: 17299435.
11. Chaurasia SS, Kaur H, de Medeiros FW, Smith SD, Wilson SE (2009) Dynamics of the expression of intermediate filaments vimentin and desmin during myofibroblast differentiation after corneal injury. Exp Eye Res 89: 590-596. doi:10.1016/S0014-4835(09)00247-4. PubMed: 19747592.
12. Fini ME, Stramer BM (2005) How the cornea heals: Cornea-specific repair mechanisms affecting surgical outcomes. Cornea 24: S2-S11. doi:10.1097/01.ico. 0000178743.06340.2c. PubMed: 16227819. (Pubitemid 41688549)
13. Wilson SE, Chaurasia SS, Medeiros FW (2007) Apoptosis in the initiation, modulation and termination of the corneal wound healing response. Exp Eye Res 85: 305-311. doi:10.1016/j.exer.2007.06.009. PubMed: 17655845. (Pubitemid 47259060)
14. Jester JV, Moller-Pedersen T, Huang J, Sax CM, Kays WT et al. (1999) The cellular basis of corneal transparency: evidence for 'corneal crystallin'. J Cell Sci 112: 613-622. PubMed: 9973596. (Pubitemid 29141981)
15. Midwood KS, Williams LV, Schwarzbauer JE (2004) Tissue repair and the dynamics of the extracellular matrix. Int J Biochem Cell Biol 36: 1031-1037. doi:10.1016/j.biocel.2003.12.003. PubMed: 15094118. (Pubitemid 38501555)
16. Yan Q, Sage EH (1999) SPARC, a matricellular glycoprotein with important biological functions. J Histochem Cytochem 47: 1495-1505. doi:10.1177/ 002215549904701201. PubMed: 10567433.
17. Soderling JA, Reed MJ, Corsa A, Sage EH (1997) Cloning and expression of murine SC1, a gene product homologous to SPARC. J Histochem Cytochem 45: 823-835. doi:10.1177/002215549704500607. PubMed: 9199668.
18. Sullivan MM, Sage EH (2004) Hevin/SC1, a matricellular glycoprotein and potential tumor-suppressor of the SPARC/BM-40/Osteonectin family. Int J Biochem Cell Biol 36: 991-996. doi:10.1016/j.biocel.2004.01.017. PubMed: 15094114. (Pubitemid 38501551)
19. Johnston IG, Paladino T, Gurd JW, Brown IR (1990) Molecular cloning of SC1-a putative brain extracellularmatrix glycoprotein showing partial similarity to osteonectin/BM-40/SPARC. Neuron 4: 165-176. doi:10.1016/0896-6273(90)90452- L. PubMed: 1690015. (Pubitemid 20149764)
20. Mothe AJ, Brown IR (2002) Effect of hyperthermia on the transport of mRNA encoding the extracellular matrix glycoprotein SC1 into Bergmann glial cell processes. Brain Res 931: 146-158. doi:10.1016/S0006-8993(02)02270-9. PubMed: 11897100. (Pubitemid 34230518)
21. Maak S, Jaesert S, Neumann K, Yerle M, von Lengerken G (2001) Isolation of expressed sequence tags of skeletal muscle of neonatal healthy and splay leg piglets and mapping by somatic cell hybrid analysis. Anim Genet 32: 303-307. doi:10.1046/j.1365-2052.2001.00778.x. PubMed: 11683718. (Pubitemid 33011524)
22. Girard JP, Springer TA (1995) Cloning from purified high endothelial venule cells of hevin, a close relative of the antiadhesive extracellular matrix protein SPARC. Immunity 2: 113-123. doi:10.1016/1074-7613(95)90083-7. PubMed: 7600298.
23. Mendis DB, Shahin S, Gurd JW, Brown IR (1994) Developmental expression in the rat cerebellum of SC1, a putative brain extracellular-matrix glycoprotein related to SPARC. Brain Res 633: 197-205. doi:10.1016/0006-8993(94)91540-7. PubMed: 8137157. (Pubitemid 24021262)
24. Mothe AJ, Brown IR (2000) Selective transport of SC1 mRNA, encoding a putative extracellular matrix glycoprotein, during postnatal development of the rat cerebellum and retina. Brain Res Mol Brain Res 76: 73-84. doi:10.1016/S0169-328X(99)00336-8. PubMed: 10719217.
25. Mothe AJ, Brown IR (2001) Differential mRNA expression of the related extracellular matrix glycoproteins SC1 and SPARC in the rat embryonic nervous system and skeletal structure. Brain Res 892: 27-41. doi:10.1016/S0006-8993(00) 03141-3. PubMed: 11172746. (Pubitemid 32126564)
26. Gongidi V, Ring C, Brekken RA, Sage EH, Rakic P et al. (2003) SPARC-like 1 is a radial glia-associated terminator of neuronal migration in cerebral cortex. Neuron 41: 57-69.
27. Girard J-P, Springer TA (1996) Modulation of endothelial cell adhesion by hevin, an acidic protein associated with high endothelial venules. J Biol Chem 271: 4511-4517. doi:10.1074/jbc.271.8.4511. PubMed: 8626806. (Pubitemid 26074151)
28. Hambrock HO, Nitsche DP, Hansen U, Bruckner P, Paulsson M et al. (2003) SC1/Hevin. An extracellular calcium-modulated protein that binds collagen I. J Biol Chem 278: 11351-11358. (Pubitemid 36792693)
29. Sullivan MM, Barker TH, Funk SE, Karchin A, Seo NS et al. (2006) Matricellular Hevin Regulates Decorin Production and Collagen Assembly. J Biol Chem 281: 27621-27632. doi:10.1074/jbc.M510507200. PubMed: 16844696. (Pubitemid 44401787)
30. Li Y, Aroca-Aguilar JD, Ghosh S, Sánchez-Sánchez F, Escribano J et al. (2006) Interaction of myocilin with the C-terminal region of hevin. Biochem Biophys Res Commun 339: 797-804. doi:10.1016/j.bbrc.2005.11.082. PubMed: 16316624. (Pubitemid 41772884)
31. Nelson PS, Plymate SR, Wang K, True LD, Ware JL et al. (1998) Hevin, an antiadhesive extracellular matrix protein, is down-regulated in metastatic prostate adenocarcinoma. Cancer Res 58: 232-236. PubMed: 9443398. (Pubitemid 28047060)
32. Esposito I, Kayed H, Keleg S, Giese T, Sage EH et al. (2007) Tumor-suppressor function of SPARC-like protein 1/Hevin in pancreatic cancer. Neoplasia 9: 8-17. doi:10.1593/neo.06646. PubMed: 17325739. (Pubitemid 46203930)
33. Kang MH, Oh DJ, Rhee DJ (2011) Effect of hevin deletion in mice and characterization in trabecular meshwork. Invest Ophthalmol Vis Sci 52: 2187-2193. doi:10.1167/iovs.10-5428. PubMed: 21220554.
34. Sullivan MM, Puolakkainen PA, Barker TH, Funk SE, Sage EH (2008) Altered tissue repair in hevin-null mice: inhibition of fibroblast migration by a matricellular SPARC homolog. Wound Repair Regen 16: 310-319. doi:10.1111/j.1524-475X.2008.00370.x. PubMed: 18318815. (Pubitemid 351342139)
35. Mohan RR, Stapleton WM, Sinha S, Netto MV, Wilson SE (2008) A novel method for generating corneal haze in anterior stroma of the mouse eye with the excimer laser. Exp Eye Res 86: 235-240. doi:10.1016/j.exer.2007.10.014. PubMed: 18068702.
36. Barbosa FL, Chaurasia SS, Cutler A, Asosingh K, Kaur H et al. (2010) Corneal myofibroblast generation from bone marrow-derived cells. Exp Eye Res 91: 92-96. doi:10.1016/j.exer.2010.04.007. PubMed: 20417632.
37. Angunawela RI, Poh R, Chaurasia SS, Tan DT, Mehta JS (2011) A mouse model of lamellar intrastromal femtosecond laser keratotomy: ultra-structural, inflammatory, and wound healing responses. Mol Vis 17: 3005-3012. PubMed: 22171154.
38. Han SB, Ang H, Balehosur D, Peh G, Chaurasia SS et al. (2013) A mouse model of corneal endothelial decompensation using cryoinjury. Mol Vis 19: 1222-1230. PubMed: 23761724.
39. Stapleton WM, Chaurasia SS, Medeiros FW, Mohan RR, Sinha S et al. (2008) Topical interleukin-1 receptor antagonist inhibits inflammatory cell infiltration into the cornea. Exp Eye Res 86: 753-757. doi:10.1016/j.exer.2008. 02.001. PubMed: 18346730.
40. Barker TH, Framson P, Puolakkainen P, Reed M, Funk SE et al. (2005) Matricellular homologs in the foreign body response. American J Pathol 166: 923-933. doi:10.1016/S0002-9440(10)62312-7.
41. Mohan RR, Hutcheon AE, Choi R, Hong J, Lee J et al. (2003) Apoptosis, necrosis, proliferation, and myofibroblast generation in the stroma following LASIK and PRK. Exp Eye Res 76: 71-87. doi:10.1016/S0014-4835(02)00251-8. PubMed: 12589777.
42. Hisatomi T, Nakao S, Murakami Y, Noda K, Nakazawa T et al. (2012) The regulatory roles of apoptosis-inducing factor in the formation and regression processes of ocular neovascularization. Am J Pathol 181: 53-61. doi:10.1016/j.ajpath.2012.03.022. PubMed: 22613025.
43. Gambato C, Ghirlando A, Moretto E, Busato F, Midena E (2005) Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes. Ophthalmology 112: 208-218. doi:10.1016/j.ophtha.2004.07.035. PubMed: 15691552.
44. Li Q, Ashraf MF, Bekoe NA, Stark WJ, Chan CC et al. (2000) The role of apoptosis in the early corneal wound healing after excimer laser keratectomy in the rat. Graefes Arch Clin Exp Ophthalmol 238: 853-860. doi:10.1007/ s004170000182. PubMed: 11127573.
45. Okanobo A, Chauhan SK, Dastjerdi MH, Kodati S, Dana R (2012) Efficacy of topical blockade of interleukin-1 in experimental dry eye disease. Am J Ophthalmol 154: 63-71. doi:10.1016/j.ajo.2011.10.002. PubMed: 22541929.
46. Saika S (2007) Yin and yang in cytokine regulation of corneal wound healing: roles of TNF-alpha. Cornea 26: S70-S74. doi:10.1097/ICO. 0b013e31812f6d14. PubMed: 17881920.
47. Kaur H, Chaurasia SS, Agrawal V, Suto C, Wilson SE (2009) Corneal myofibroblast viability: opposing effects of IL-1 and TGF beta1. Exp Eye Res 89: 152-158. doi:10.1016/j.exer.2009.03.001. PubMed: 19285499.
48. Bradshaw AD (2012) Diverse biological functions of the SPARC family of proteins. Int J Biochem Cell Biol 44: 480-488. doi:10.1016/j.biocel.2011.12.021. PubMed: 22249026.
49. Tervo T, Moilanen J (2003) In vivo confocal microscopy for evaluation of wound healing following corneal refractive surgery. Prog Retin Eye Res 22: 339-358. doi:10.1016/S1350-9462(02)00064-2. PubMed: 12852490.
50. Nakayasu K, Tanaka M, Konomi H, Hayashi T (1986) Distribution of types I, II, III, IV and V collagen in normal and keratoconus corneas. Ophthalmic Res 18: 1-10. doi:10.1159/000265406. PubMed: 3513078.
51. Girard J-P, Springer TA (1996) Modulation of endothelial cell adhesion by hevin, an acidic protein associated with high endothelial venules. J Biol Chem 271: 4511-4517. doi:10.1074/jbc.271.8.4511. PubMed: 8626806.
52. St Croix B, Rago C, Velculescu V, Traverso G, Romans KE et al. (2000) Genes expressed in human tumor endothelium. Science 289: 1197-1202. doi:10.1126/science.289.5482.1197. PubMed: 10947988.
53. Reed MJ, Puolakkainen P, Lane TF, Dickerson D, Bornstein P et al. (1993) Differential expression of SPARC and thrombospondin 1 in wound repair: immunolocalization and in situ hybridization. J Histochem Cytochem 41: 1467-1477. doi:10.1177/41.10.8245406. PubMed: 8245406.