Heterogeneous susceptibility of valve endothelial cells to mesenchymal transformation in response to TNFα

Annals of Biomedical Engineering

Volumn 42, Issue 1, 2014, Pages 149-161

  Farrar, Emily J ^a   Butcher, Jonathan T ^a  

^a Cornell University   (United States)

Author keywords

Aortic valve; Calcification; EMT; Inflammation; Invasion; Membrane; Valve interstitial cells

Indexed keywords

AORTIC VALVES; EMT; INFLAMMATION; INVASION; VALVE INTERSTITIAL CELLS;

BIOMINERALIZATION; BONE; CALCIFICATION (BIOCHEMISTRY); CYTOLOGY; DIAGNOSIS; MEMBRANES; PATHOLOGY; PROTEINS;

ENDOTHELIAL CELLS;

ALPHA SMOOTH MUSCLE ACTIN; BONE MORPHOGENETIC PROTEIN 4; COLLAGEN FIBER; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GELATINASE B; INTERCELLULAR ADHESION MOLECULE 1; MESSENGER RNA; NOTCH1 RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; VASCULAR ENDOTHELIAL CADHERIN;

AMINO ACID SEQUENCE; ANIMAL CELL; AORTA VALVE; ARTICLE; CELL INVASION; CELL ISOLATION; CONTROLLED STUDY; ENDOTHELIUM CELL; EPITHELIAL MESENCHYMAL TRANSITION; EXTRACELLULAR MATRIX; HYDROGEL; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; TISSUE CULTURE; UPREGULATION;

ANIMALS; ANTIGENS, CD; AORTIC VALVE; CADHERINS; CELL TRANSDIFFERENTIATION; CELLS, CULTURED; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; MATRIX METALLOPROTEINASE 9; RECEPTOR, NOTCH1; SWINE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84896701678     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-013-0894-3     Document Type: Article

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