The acute-phase protein PTX3 is an essential mediator of glial scar formation and resolution of brain edema after ischemic injury

Journal of Cerebral Blood Flow and Metabolism

Volumn 34, Issue 3, 2014, Pages 480-488

  Rodriguez Grande, Beatriz ^a   Swana, Matimba ^a   Nguyen, Loan ^a   Englezou, Pavlos ^a   Maysami, Samaneh ^a   Allan, Stuart M ^a   Rothwell, Nancy J ^a   Garlanda, Cecilia ^b   Denes, Adam ^a,c   Pinteaux, Emmanuel ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^c INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

brain inflammation; cerebral ischemia; edema; glial scar; IL 1; pentraxin 3

Indexed keywords

INTERLEUKIN 1; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; PENTRAXIN 3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CELL CULTURE; BRAIN EDEMA; BRAIN ISCHEMIA; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; EXPERIMENTAL STROKE; EXTRACELLULAR MATRIX; GENE DELETION; GLIA; GLIA SCAR; IN VITRO STUDY; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCAR FORMATION; WILD TYPE;

ANIMALS; BRAIN EDEMA; BRAIN ISCHEMIA; C-REACTIVE PROTEIN; CELL PROLIFERATION; CICATRIX; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; INTERLEUKIN-1ALPHA; INTERLEUKIN-1BETA; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; NEUROGLIA;

EID: 84896700963     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2013.224     Document Type: Article

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