-
1
-
-
43249108164
-
Nanotechnologies and cancer: diagnosis and therapeutic future
-
Lansiaux A. Nanotechnologies and cancer: diagnosis and therapeutic future. Bull. Cancer 2008, 95:391-391.
-
(2008)
Bull. Cancer
, vol.95
, pp. 391-391
-
-
Lansiaux, A.1
-
2
-
-
78650039534
-
Preliminary evaluation of a nanotechnology-based approach for the more effective diagnosis of colon cancers
-
Lue N., Ganta S., Hammer D.X., Mujat M., Stevens A.E., Harrison L., Ferguson R.D., Rosen D., Amiji M., Iftimia N. Preliminary evaluation of a nanotechnology-based approach for the more effective diagnosis of colon cancers. Nanomedicine 2010, 5:1467-1479.
-
(2010)
Nanomedicine
, vol.5
, pp. 1467-1479
-
-
Lue, N.1
Ganta, S.2
Hammer, D.X.3
Mujat, M.4
Stevens, A.E.5
Harrison, L.6
Ferguson, R.D.7
Rosen, D.8
Amiji, M.9
Iftimia, N.10
-
3
-
-
77955209935
-
In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles
-
Koo H., Lee H., Lee S., Min K.H., Kim M.S., Lee D.S., Choi Y., Kwon I.C., Kim K., Jeong S.Y. In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles. Chem. Commun. (Camb.) 2010, 46:5668-5670.
-
(2010)
Chem. Commun. (Camb.)
, vol.46
, pp. 5668-5670
-
-
Koo, H.1
Lee, H.2
Lee, S.3
Min, K.H.4
Kim, M.S.5
Lee, D.S.6
Choi, Y.7
Kwon, I.C.8
Kim, K.9
Jeong, S.Y.10
-
4
-
-
84896709687
-
Nanoparticle 'fingerprinting' technique could improve cancer diagnosis
-
Nanoparticle 'fingerprinting' technique could improve cancer diagnosis. Bioanalysis 2009, 1:270-270.
-
(2009)
Bioanalysis
, vol.1
, pp. 270-270
-
-
-
5
-
-
84896722079
-
The potential of targeting nanoparticle for breast cancer diagnosis
-
Iwakuma N., Toh U., Grobmyer S.R., Koura K., Takenaka M., Otsuka H., Takahashi R., Shirouzu K. The potential of targeting nanoparticle for breast cancer diagnosis. Eur. J. Cancer 2012, 48:S62-S62.
-
(2012)
Eur. J. Cancer
, vol.48
-
-
Iwakuma, N.1
Toh, U.2
Grobmyer, S.R.3
Koura, K.4
Takenaka, M.5
Otsuka, H.6
Takahashi, R.7
Shirouzu, K.8
-
6
-
-
84864129727
-
Toward a siRNA-containing nanoparticle targeted to breast cancer cells and the tumor microenvironment
-
Gomes-da-Silva L.C., Santos A.O., Bimbo L.M., Moura V., Ramalho J.S., de Lima M.C.P., Simoes S., Moreira J.N. Toward a siRNA-containing nanoparticle targeted to breast cancer cells and the tumor microenvironment. Int. J. Pharm. 2012, 434:9-19.
-
(2012)
Int. J. Pharm.
, vol.434
, pp. 9-19
-
-
Gomes-da-Silva, L.C.1
Santos, A.O.2
Bimbo, L.M.3
Moura, V.4
Ramalho, J.S.5
de Lima, M.C.P.6
Simoes, S.7
Moreira, J.N.8
-
7
-
-
84865328172
-
The effect of mechanical properties of iron oxide nanoparticle-loaded functional nano-carrier on tumor targeting and imaging
-
Choi W.I., Kim J.Y., Heo S.U., Jeong Y.Y., Kim Y.H., Tae G. The effect of mechanical properties of iron oxide nanoparticle-loaded functional nano-carrier on tumor targeting and imaging. J. Control. Release 2012, 162:267-275.
-
(2012)
J. Control. Release
, vol.162
, pp. 267-275
-
-
Choi, W.I.1
Kim, J.Y.2
Heo, S.U.3
Jeong, Y.Y.4
Kim, Y.H.5
Tae, G.6
-
8
-
-
84857512892
-
The ligand nanoparticle conjugation approach for targeted cancer therapy
-
Karra N., Benita S. The ligand nanoparticle conjugation approach for targeted cancer therapy. Curr. Drug Metab. 2012, 13:22-41.
-
(2012)
Curr. Drug Metab.
, vol.13
, pp. 22-41
-
-
Karra, N.1
Benita, S.2
-
9
-
-
81855218249
-
Nanoparticle-mediated measurement of target-drug binding in cancer cells
-
Ullal A.V., Reiner T., Yang K.S., Gorbatov R., Min C., Issadore D., Lee H., Weissleder R. Nanoparticle-mediated measurement of target-drug binding in cancer cells. ACS Nano 2011, 5:9216-9224.
-
(2011)
ACS Nano
, vol.5
, pp. 9216-9224
-
-
Ullal, A.V.1
Reiner, T.2
Yang, K.S.3
Gorbatov, R.4
Min, C.5
Issadore, D.6
Lee, H.7
Weissleder, R.8
-
10
-
-
84865998674
-
PH and redox dual responsive nanoparticle for nuclear targeted drug delivery
-
Bahadur K.C.R., Thapa B., Xu P.S. pH and redox dual responsive nanoparticle for nuclear targeted drug delivery. Mol. Pharm. 2012, 9:2719-2729.
-
(2012)
Mol. Pharm.
, vol.9
, pp. 2719-2729
-
-
Bahadur, K.C.R.1
Thapa, B.2
Xu, P.S.3
-
11
-
-
80052950773
-
Simultaneous detection of intracellular tumor mrna with bi-color imaging based on a gold nanoparticle/molecular beacon
-
Qiao G.M., Gao Y., Li N., Yu Z.Z., Zhuo L.H., Tang B. Simultaneous detection of intracellular tumor mrna with bi-color imaging based on a gold nanoparticle/molecular beacon. Chem. Eur. J. 2011, 17:11210-11215.
-
(2011)
Chem. Eur. J.
, vol.17
, pp. 11210-11215
-
-
Qiao, G.M.1
Gao, Y.2
Li, N.3
Yu, Z.Z.4
Zhuo, L.H.5
Tang, B.6
-
12
-
-
84855807815
-
A novel clinically translatable fluorescent nanoparticle for targeted molecular imaging of tumors in living subjects
-
Gao J.H., Chen K., Luong R., Bouley D.M., Mao H., Qiao T.C., Gambhir S.S., Cheng Z. A novel clinically translatable fluorescent nanoparticle for targeted molecular imaging of tumors in living subjects. Nano Lett. 2012, 12:281-286.
-
(2012)
Nano Lett.
, vol.12
, pp. 281-286
-
-
Gao, J.H.1
Chen, K.2
Luong, R.3
Bouley, D.M.4
Mao, H.5
Qiao, T.C.6
Gambhir, S.S.7
Cheng, Z.8
-
13
-
-
61549111300
-
Nanoparticle-enabled terahertz imaging for cancer diagnosis
-
Oh S.J., Kang J., Maeng I., Suh J.S., Huh Y.M., Haam S., Son J.H. Nanoparticle-enabled terahertz imaging for cancer diagnosis. Opt. Express 2009, 17:3469-3475.
-
(2009)
Opt. Express
, vol.17
, pp. 3469-3475
-
-
Oh, S.J.1
Kang, J.2
Maeng, I.3
Suh, J.S.4
Huh, Y.M.5
Haam, S.6
Son, J.H.7
-
14
-
-
67649813881
-
Current status of nanoparticle-based imaging agents for early diagnosis of cancer and atherosclerosis
-
Saravanakumar G., Kim K., Park J.H., Rhee K., Kwon I.C. Current status of nanoparticle-based imaging agents for early diagnosis of cancer and atherosclerosis. J. Biomed. Nanotechnol. 2009, 5:20-35.
-
(2009)
J. Biomed. Nanotechnol.
, vol.5
, pp. 20-35
-
-
Saravanakumar, G.1
Kim, K.2
Park, J.H.3
Rhee, K.4
Kwon, I.C.5
-
15
-
-
84867673182
-
Applications of polymeric micelles with tumor targeted in chemotherapy
-
Ding H., Wang X.J., Zhang S., Liu X.L. Applications of polymeric micelles with tumor targeted in chemotherapy. J. Nanopart. Res. 2012, 14.
-
(2012)
J. Nanopart. Res.
, vol.14
-
-
Ding, H.1
Wang, X.J.2
Zhang, S.3
Liu, X.L.4
-
16
-
-
84870380689
-
Multi-dye theranostic nanoparticle platform for bioimaging and cancer therapy
-
Singh A.K., Hahn M.A., Gutwein L.G., Rule M.C., Knapik J.A., Moudgil B.M., Grobmyer S.R., Brown S.C. Multi-dye theranostic nanoparticle platform for bioimaging and cancer therapy. Int. J. Nanomedicine 2012, 7:2739-2750.
-
(2012)
Int. J. Nanomedicine
, vol.7
, pp. 2739-2750
-
-
Singh, A.K.1
Hahn, M.A.2
Gutwein, L.G.3
Rule, M.C.4
Knapik, J.A.5
Moudgil, B.M.6
Grobmyer, S.R.7
Brown, S.C.8
-
17
-
-
84866756419
-
Preclinical evaluation of injectable sirolimus formulated with polymeric nanoparticle for cancer therapy
-
Woo H.N., Chung H.K., Ju E.J., Jung J., Kang H.W., Lee S.W., Seo M.H., Lee J.S., Lee J.S., Park H.J., Song S.Y., Jeong S.Y., Choi E.K. Preclinical evaluation of injectable sirolimus formulated with polymeric nanoparticle for cancer therapy. Int. J. Nanomedicine 2012, 7:2197-2208.
-
(2012)
Int. J. Nanomedicine
, vol.7
, pp. 2197-2208
-
-
Woo, H.N.1
Chung, H.K.2
Ju, E.J.3
Jung, J.4
Kang, H.W.5
Lee, S.W.6
Seo, M.H.7
Lee, J.S.8
Lee, J.S.9
Park, H.J.10
Song, S.Y.11
Jeong, S.Y.12
Choi, E.K.13
-
18
-
-
79954579637
-
Design of biocompatible dendrimers for cancer diagnosis and therapy: current status and future perspectives
-
Cheng Y.Y., Zhao L.B., Li Y.W., Xu T.W. Design of biocompatible dendrimers for cancer diagnosis and therapy: current status and future perspectives. Chem. Soc. Rev. 2011, 40:2673-2703.
-
(2011)
Chem. Soc. Rev.
, vol.40
, pp. 2673-2703
-
-
Cheng, Y.Y.1
Zhao, L.B.2
Li, Y.W.3
Xu, T.W.4
-
19
-
-
80054766164
-
Application of near-infrared fluorescence imaging using a polymeric nanoparticle-based probe for the diagnosis and therapeutic monitoring of colon cancer
-
Yoon S.M., Myung S.J., Kim I.W., Do E.J., Ye B.D., Ryu J.H., Park K., Kim K., Kwon I.C., Kim M.J., Moon D.H., Yang D.H., Kim K.J., Byeon J.S., Yang S.K., Kim J.H. Application of near-infrared fluorescence imaging using a polymeric nanoparticle-based probe for the diagnosis and therapeutic monitoring of colon cancer. Dig. Dis. Sci. 2011, 56:3005-3013.
-
(2011)
Dig. Dis. Sci.
, vol.56
, pp. 3005-3013
-
-
Yoon, S.M.1
Myung, S.J.2
Kim, I.W.3
Do, E.J.4
Ye, B.D.5
Ryu, J.H.6
Park, K.7
Kim, K.8
Kwon, I.C.9
Kim, M.J.10
Moon, D.H.11
Yang, D.H.12
Kim, K.J.13
Byeon, J.S.14
Yang, S.K.15
Kim, J.H.16
-
20
-
-
84896721322
-
-
Kong X.G., Liu X.M., Sun Y.J., Yu Y., Zhang Y.L. Aoe, Multifunctional Nanoparticle with Diagnosis and Therapeutics for Tumour 2009.
-
(2009)
Aoe, Multifunctional Nanoparticle with Diagnosis and Therapeutics for Tumour
-
-
Kong, X.G.1
Liu, X.M.2
Sun, Y.J.3
Yu, Y.4
Zhang, Y.L.5
-
21
-
-
35348882024
-
Nanotechnology applications in cancer
-
Nie S., Xing Y., Kim G.J., Simons J.W. Nanotechnology applications in cancer. Annu. Rev. Biomed. Eng. 2007, 9:257-288.
-
(2007)
Annu. Rev. Biomed. Eng.
, vol.9
, pp. 257-288
-
-
Nie, S.1
Xing, Y.2
Kim, G.J.3
Simons, J.W.4
-
22
-
-
0038197607
-
Diacyllipid-polymer micelles as nanocarriers for poorly soluble anticancer drugs
-
Gao Z.G., Lukyanov A.N., Singhal A., Torchilin V.P. Diacyllipid-polymer micelles as nanocarriers for poorly soluble anticancer drugs. Nano Lett. 2002, 2:979-982.
-
(2002)
Nano Lett.
, vol.2
, pp. 979-982
-
-
Gao, Z.G.1
Lukyanov, A.N.2
Singhal, A.3
Torchilin, V.P.4
-
23
-
-
51049090204
-
Nanoparticle therapeutics: an emerging treatment modality for cancer
-
Davis M.E., Chen Z.G., Shin D.M. Nanoparticle therapeutics: an emerging treatment modality for cancer. Nat. Rev. Drug. Discov. 2008, 7:771-782.
-
(2008)
Nat. Rev. Drug. Discov.
, vol.7
, pp. 771-782
-
-
Davis, M.E.1
Chen, Z.G.2
Shin, D.M.3
-
24
-
-
84868256944
-
Overcoming limitations in nanoparticle drug delivery: triggered, intravascular release to improve drug penetration into tumors
-
Manzoor A.A., Lindner L.H., Landon C.D., Park J.Y., Simnick A.J., Dreher M.R., Das S., Hanna G., Park W., Chilkoti A., Koning G.A., ten Hagen T.L.M., Needham D., Dewhirst M.W. Overcoming limitations in nanoparticle drug delivery: triggered, intravascular release to improve drug penetration into tumors. Cancer Res. 2012, 72:5566-5575.
-
(2012)
Cancer Res.
, vol.72
, pp. 5566-5575
-
-
Manzoor, A.A.1
Lindner, L.H.2
Landon, C.D.3
Park, J.Y.4
Simnick, A.J.5
Dreher, M.R.6
Das, S.7
Hanna, G.8
Park, W.9
Chilkoti, A.10
Koning, G.A.11
ten Hagen, T.L.M.12
Needham, D.13
Dewhirst, M.W.14
-
25
-
-
84870408164
-
Probing of the assembly structure and dynamics within nanoparticles during interaction with blood proteins
-
Li Y., Budamagunta M.S., Luo J., Xiao W., Voss J.C., Lam K.S. Probing of the assembly structure and dynamics within nanoparticles during interaction with blood proteins. ACS Nano 2012, 6:9485-9495.
-
(2012)
ACS Nano
, vol.6
, pp. 9485-9495
-
-
Li, Y.1
Budamagunta, M.S.2
Luo, J.3
Xiao, W.4
Voss, J.C.5
Lam, K.S.6
-
26
-
-
35349022545
-
Hydrolysable core-crosslinked thermosensitive polymeric micelles: synthesis, characterisation and in vivo studies
-
Rijcken C.J., Snel C.J., Schiffelers R.M., van Nostrum C.F., Hennink W.E. Hydrolysable core-crosslinked thermosensitive polymeric micelles: synthesis, characterisation and in vivo studies. Biomaterials 2007, 28:5581-5593.
-
(2007)
Biomaterials
, vol.28
, pp. 5581-5593
-
-
Rijcken, C.J.1
Snel, C.J.2
Schiffelers, R.M.3
van Nostrum, C.F.4
Hennink, W.E.5
-
27
-
-
84875647859
-
Making polymeric nanoparticles stimuli-responsive with dynamic covalent bonds
-
Jackson A.W., Fulton D.A. Making polymeric nanoparticles stimuli-responsive with dynamic covalent bonds. Polym. Chem. 2013, 4:31-45.
-
(2013)
Polym. Chem.
, vol.4
, pp. 31-45
-
-
Jackson, A.W.1
Fulton, D.A.2
-
28
-
-
84870538030
-
Lysine-block-tyrosine block copolypeptides: Self-assembly, cross-linking, and conjugation of targeted ligand for drug encapsulation
-
Huang Y.C., Yang Y.S., Lai T.Y., Jan J.S. Lysine-block-tyrosine block copolypeptides: Self-assembly, cross-linking, and conjugation of targeted ligand for drug encapsulation. Polymer 2012, 53:913-922.
-
(2012)
Polymer
, vol.53
, pp. 913-922
-
-
Huang, Y.C.1
Yang, Y.S.2
Lai, T.Y.3
Jan, J.S.4
-
29
-
-
72449122860
-
Reversibly stabilized multifunctional dextran nanoparticles efficiently deliver doxorubicin into the nuclei of cancer cells
-
Li Y.L., Zhu L., Liu Z.Z., Cheng R., Meng F.H., Cui J.H., Ji S.J., Zhong Z.Y. Reversibly stabilized multifunctional dextran nanoparticles efficiently deliver doxorubicin into the nuclei of cancer cells. Angew. Chem. Int. Edit. 2009, 48:9914-9918.
-
(2009)
Angew. Chem. Int. Edit.
, vol.48
, pp. 9914-9918
-
-
Li, Y.L.1
Zhu, L.2
Liu, Z.Z.3
Cheng, R.4
Meng, F.H.5
Cui, J.H.6
Ji, S.J.7
Zhong, Z.Y.8
-
30
-
-
84865788328
-
Biological stimuli responsive drug carriers based on keratin for triggerable drug delivery
-
Li Q.M., Zhu L.J., Liu R.G., Huang D., Jin X., Che N., Li Z., Qu X.Z., Kang H.L., Huang Y. Biological stimuli responsive drug carriers based on keratin for triggerable drug delivery. J. Mater. Chem. 2012, 22:19964-19973.
-
(2012)
J. Mater. Chem.
, vol.22
, pp. 19964-19973
-
-
Li, Q.M.1
Zhu, L.J.2
Liu, R.G.3
Huang, D.4
Jin, X.5
Che, N.6
Li, Z.7
Qu, X.Z.8
Kang, H.L.9
Huang, Y.10
-
31
-
-
84869038084
-
Intracellular drug release nanosystems
-
Meng F.H., Cheng R., Deng C., Zhong Z.Y. Intracellular drug release nanosystems. Mater. Today 2012, 15:436-442.
-
(2012)
Mater. Today
, vol.15
, pp. 436-442
-
-
Meng, F.H.1
Cheng, R.2
Deng, C.3
Zhong, Z.Y.4
-
32
-
-
84860157388
-
Stimuli-responsive amphiphilic polyelectrolyte heptablock copolymer physical hydrogels: an unusual pH-response
-
Popescu M.T., Tsitsilianis C., Papadakis C.M., Adelsberger J., Balog S., Busch P., Hadjiantoniou N.A., Patrickios C.S. Stimuli-responsive amphiphilic polyelectrolyte heptablock copolymer physical hydrogels: an unusual pH-response. Macromolecules 2012, 45:3523-3530.
-
(2012)
Macromolecules
, vol.45
, pp. 3523-3530
-
-
Popescu, M.T.1
Tsitsilianis, C.2
Papadakis, C.M.3
Adelsberger, J.4
Balog, S.5
Busch, P.6
Hadjiantoniou, N.A.7
Patrickios, C.S.8
-
33
-
-
84871201938
-
Novel shell-cross-linked micelles with detachable PEG corona for glutathione-mediated intracellular drug delivery
-
Wang K., Liu Y., Yi W.J., Li C., Li Y.Y., Zhuo R.X., Zhang X.Z. Novel shell-cross-linked micelles with detachable PEG corona for glutathione-mediated intracellular drug delivery. Soft Matter 2013, 9:692-699.
-
(2013)
Soft Matter
, vol.9
, pp. 692-699
-
-
Wang, K.1
Liu, Y.2
Yi, W.J.3
Li, C.4
Li, Y.Y.5
Zhuo, R.X.6
Zhang, X.Z.7
-
34
-
-
64149094873
-
Stimuli-responsive polymersomes for programmed drug delivery
-
Meng F., Zhong Z., Feijen J. Stimuli-responsive polymersomes for programmed drug delivery. Biomacromolecules 2009, 10:197-209.
-
(2009)
Biomacromolecules
, vol.10
, pp. 197-209
-
-
Meng, F.1
Zhong, Z.2
Feijen, J.3
-
35
-
-
57349111147
-
Disulfide-cross-linked PEG-poly(amino acid)s copolymer micelles for glutathione-mediated intracellular drug delivery
-
Koo A.N., Lee H.J., Kim S.E., Chang J.H., Park C., Kim C., Park J.H., Lee S.C. Disulfide-cross-linked PEG-poly(amino acid)s copolymer micelles for glutathione-mediated intracellular drug delivery. Chem. Commun. (Camb.) 2008, 6570-6572.
-
(2008)
Chem. Commun. (Camb.)
, pp. 6570-6572
-
-
Koo, A.N.1
Lee, H.J.2
Kim, S.E.3
Chang, J.H.4
Park, C.5
Kim, C.6
Park, J.H.7
Lee, S.C.8
-
36
-
-
84870595778
-
PH-responsive peptide mimic shell cross-linked magnetic nanocarriers for combination therapy
-
Barick K.C., Singh S., Jadhav N.V., Bahadur D., Pandey B.N., Hassan P.A. pH-responsive peptide mimic shell cross-linked magnetic nanocarriers for combination therapy. Adv. Funct. Mater. 2012, 22:4975-4984.
-
(2012)
Adv. Funct. Mater.
, vol.22
, pp. 4975-4984
-
-
Barick, K.C.1
Singh, S.2
Jadhav, N.V.3
Bahadur, D.4
Pandey, B.N.5
Hassan, P.A.6
-
37
-
-
84859177827
-
Triggering polymeric nanoparticle disassembly through the simultaneous application of two different stimuli
-
Jackson A.W., Fulton D.A. Triggering polymeric nanoparticle disassembly through the simultaneous application of two different stimuli. Macromolecules 2012, 45:2699-2708.
-
(2012)
Macromolecules
, vol.45
, pp. 2699-2708
-
-
Jackson, A.W.1
Fulton, D.A.2
-
38
-
-
37549011782
-
Aldehyde surface-functionalized shell cross-linked micelles with pH-tunable core swellability and their bioconjugation with lysozyme
-
Liu H., Jiang X.Z., Fan J., Wang G.H., Liu S.Y. Aldehyde surface-functionalized shell cross-linked micelles with pH-tunable core swellability and their bioconjugation with lysozyme. Macromolecules 2007, 40:9074-9083.
-
(2007)
Macromolecules
, vol.40
, pp. 9074-9083
-
-
Liu, H.1
Jiang, X.Z.2
Fan, J.3
Wang, G.H.4
Liu, S.Y.5
-
39
-
-
2542551131
-
Determination of the bioavailability of biotin conjugated onto shell cross-linked (SCK) nanoparticles
-
Qi K., Ma Q.G., Remsen E.E., Clark C.G., Wooley K.L. Determination of the bioavailability of biotin conjugated onto shell cross-linked (SCK) nanoparticles. J. Am. Chem. Soc. 2004, 126:6599-6607.
-
(2004)
J. Am. Chem. Soc.
, vol.126
, pp. 6599-6607
-
-
Qi, K.1
Ma, Q.G.2
Remsen, E.E.3
Clark, C.G.4
Wooley, K.L.5
-
40
-
-
48449093298
-
Acid-labile core cross-linked micelles for pH-triggered release of antitumor drugs
-
Chan Y., Wong T., Byrne F., Kavallaris M., Bulmus V. Acid-labile core cross-linked micelles for pH-triggered release of antitumor drugs. Biomacromolecules 2008, 9:1826-1836.
-
(2008)
Biomacromolecules
, vol.9
, pp. 1826-1836
-
-
Chan, Y.1
Wong, T.2
Byrne, F.3
Kavallaris, M.4
Bulmus, V.5
-
41
-
-
71949095056
-
Degradable Thermo responsive Core Cross-Linked Micelles: Fabrication, Surface Functionalization, and Biorecognition
-
Jiang X.Z., Liu S.Y., Narain R. Degradable Thermo responsive Core Cross-Linked Micelles: Fabrication, Surface Functionalization, and Biorecognition. Langmuir 2009, 25:13344-13350.
-
(2009)
Langmuir
, vol.25
, pp. 13344-13350
-
-
Jiang, X.Z.1
Liu, S.Y.2
Narain, R.3
-
42
-
-
33750960634
-
Supramolecular assemblies of block copolymers in aqueous media as nanocontainers relevant to biological applications
-
Harada A., Kataoka K. Supramolecular assemblies of block copolymers in aqueous media as nanocontainers relevant to biological applications. Prog. Polym. Sci. 2006, 31:949-982.
-
(2006)
Prog. Polym. Sci.
, vol.31
, pp. 949-982
-
-
Harada, A.1
Kataoka, K.2
-
43
-
-
84863230233
-
Well-defined, reversible boronate crosslinked nanocarriers for targeted drug delivery in response to acidic pH values and cis-diols
-
Li Y., Xiao W., Xiao K., Berti L., Luo J., Tseng H.P., Fung G., Lam K.S. Well-defined, reversible boronate crosslinked nanocarriers for targeted drug delivery in response to acidic pH values and cis-diols. Angew. Chem. Int. Ed. Engl. 2012, 51:2864-2869.
-
(2012)
Angew. Chem. Int. Ed. Engl.
, vol.51
, pp. 2864-2869
-
-
Li, Y.1
Xiao, W.2
Xiao, K.3
Berti, L.4
Luo, J.5
Tseng, H.P.6
Fung, G.7
Lam, K.S.8
-
44
-
-
79960086599
-
Well-defined, reversible disulfide cross-linked micelles for on-demand paclitaxel delivery
-
Li Y., Xiao K., Luo J., Xiao W., Lee J.S., Gonik A.M., Kato J., Dong T.A., Lam K.S. Well-defined, reversible disulfide cross-linked micelles for on-demand paclitaxel delivery. Biomaterials 2011, 32:6633-6645.
-
(2011)
Biomaterials
, vol.32
, pp. 6633-6645
-
-
Li, Y.1
Xiao, K.2
Luo, J.3
Xiao, W.4
Lee, J.S.5
Gonik, A.M.6
Kato, J.7
Dong, T.A.8
Lam, K.S.9
-
45
-
-
69849089755
-
Biodegradable micelles with sheddable poly(ethylene glycol) shells for triggered intracellular release of doxorubicin
-
Sun H., Guo B., Cheng R., Meng F., Liu H., Zhong Z. Biodegradable micelles with sheddable poly(ethylene glycol) shells for triggered intracellular release of doxorubicin. Biomaterials 2009, 30:6358-6366.
-
(2009)
Biomaterials
, vol.30
, pp. 6358-6366
-
-
Sun, H.1
Guo, B.2
Cheng, R.3
Meng, F.4
Liu, H.5
Zhong, Z.6
-
46
-
-
77955768765
-
Core-crosslinked polymeric micelles with controlled release of covalently entrapped doxorubicin
-
Talelli M., Iman M., Varkouhi A.K., Rijcken C.J., Schiffelers R.M., Etrych T., Ulbrich K., van Nostrum C.F., Lammers T., Storm G., Hennink W.E. Core-crosslinked polymeric micelles with controlled release of covalently entrapped doxorubicin. Biomaterials 2010, 31:7797-7804.
-
(2010)
Biomaterials
, vol.31
, pp. 7797-7804
-
-
Talelli, M.1
Iman, M.2
Varkouhi, A.K.3
Rijcken, C.J.4
Schiffelers, R.M.5
Etrych, T.6
Ulbrich, K.7
van Nostrum, C.F.8
Lammers, T.9
Storm, G.10
Hennink, W.E.11
-
47
-
-
77951611392
-
Reduction-sensitive self-aggregates as a novel delivery system
-
Kim J.E., Cha E.J., Ahn C.H. Reduction-sensitive self-aggregates as a novel delivery system. Macromol. Chem. Phys. 2010, 211:956-961.
-
(2010)
Macromol. Chem. Phys.
, vol.211
, pp. 956-961
-
-
Kim, J.E.1
Cha, E.J.2
Ahn, C.H.3
-
48
-
-
78751702186
-
Shell cross-linked and hepatocyte-targeting nanoparticles containing doxorubicin via acid-cleavable linkage
-
Xing M.M.Q., Lu C.H., Zhong W. Shell cross-linked and hepatocyte-targeting nanoparticles containing doxorubicin via acid-cleavable linkage. Nanomedicine Nanotechnol. 2011, 7:80-87.
-
(2011)
Nanomedicine Nanotechnol.
, vol.7
, pp. 80-87
-
-
Xing, M.M.Q.1
Lu, C.H.2
Zhong, W.3
-
49
-
-
80052149525
-
Targeted core-crosslinked polymeric micelles with controlled release of covalently entrapped doxorubicin
-
Talelli M., Iman M., Rijcken C.J., van Nostrum C.F., Hennink W.E. Targeted core-crosslinked polymeric micelles with controlled release of covalently entrapped doxorubicin. J. Control. Release 2010, 148:e121-e122.
-
(2010)
J. Control. Release
, vol.148
-
-
Talelli, M.1
Iman, M.2
Rijcken, C.J.3
van Nostrum, C.F.4
Hennink, W.E.5
-
50
-
-
79953854925
-
Ketal cross-linked poly(ethylene glycol)-poly(amino acid)s copolymer micelles for efficient intracellular delivery of doxorubicin
-
Lee S.J., Min K.H., Lee H.J., Koo A.N., Rim H.P., Jeon B.J., Jeong S.Y., Heo J.S., Lee S.C. Ketal cross-linked poly(ethylene glycol)-poly(amino acid)s copolymer micelles for efficient intracellular delivery of doxorubicin. Biomacromolecules 2011, 12:1224-1233.
-
(2011)
Biomacromolecules
, vol.12
, pp. 1224-1233
-
-
Lee, S.J.1
Min, K.H.2
Lee, H.J.3
Koo, A.N.4
Rim, H.P.5
Jeon, B.J.6
Jeong, S.Y.7
Heo, J.S.8
Lee, S.C.9
-
51
-
-
42949103542
-
PEG-detachable polyplex micelles based on disulfide-linked block catiomers as bioresponsive nonviral gene vectors
-
Takae S., Miyata K., Oba M., Ishii T., Nishiyama N., Itaka K., Yamasaki Y., Koyama H., Kataoka K. PEG-detachable polyplex micelles based on disulfide-linked block catiomers as bioresponsive nonviral gene vectors. J. Am. Chem. Soc. 2008, 130:6001-6009.
-
(2008)
J. Am. Chem. Soc.
, vol.130
, pp. 6001-6009
-
-
Takae, S.1
Miyata, K.2
Oba, M.3
Ishii, T.4
Nishiyama, N.5
Itaka, K.6
Yamasaki, Y.7
Koyama, H.8
Kataoka, K.9
-
52
-
-
0025941693
-
The role of glutathione-dependent enzymes in drug resistance
-
Black S.M., Wolf C.R. The role of glutathione-dependent enzymes in drug resistance. Pharmacol. Ther. 1991, 51:139-154.
-
(1991)
Pharmacol. Ther.
, vol.51
, pp. 139-154
-
-
Black, S.M.1
Wolf, C.R.2
-
53
-
-
0035400270
-
Mechanisms of resistance to cisplatin
-
Kartalou M., Essigmann J.M. Mechanisms of resistance to cisplatin. Mutat. Res. 2001, 478:23-43.
-
(2001)
Mutat. Res.
, vol.478
, pp. 23-43
-
-
Kartalou, M.1
Essigmann, J.M.2
-
54
-
-
77954209302
-
Core-shell-corona micelle stabilized by reversible cross-linkage for intracellular drug delivery
-
Wang Y.C., Li Y., Sun T.M., Xiong M.H., Wu J., Yang Y.Y., Wang J. Core-shell-corona micelle stabilized by reversible cross-linkage for intracellular drug delivery. Macromol. Rapid Commun. 2010, 31:1201-1206.
-
(2010)
Macromol. Rapid Commun.
, vol.31
, pp. 1201-1206
-
-
Wang, Y.C.1
Li, Y.2
Sun, T.M.3
Xiong, M.H.4
Wu, J.5
Yang, Y.Y.6
Wang, J.7
-
55
-
-
84862023516
-
Disulfide cross-linked micelles for the targeted delivery of vincristine to B-cell lymphoma
-
Kato J., Li Y., Xiao K., Lee J.S., Luo J., Tuscano J.M., O'Donnell R.T., Lam K.S. Disulfide cross-linked micelles for the targeted delivery of vincristine to B-cell lymphoma. Mol. Pharm. 2012, 9:1727-1735.
-
(2012)
Mol. Pharm.
, vol.9
, pp. 1727-1735
-
-
Kato, J.1
Li, Y.2
Xiao, K.3
Lee, J.S.4
Luo, J.5
Tuscano, J.M.6
O'Donnell, R.T.7
Lam, K.S.8
-
56
-
-
0035214028
-
Efficient gene transfer using reversibly cross-linked low molecular weight polyethylenimine
-
Gosselin M.A., Guo W., Lee R.J. Efficient gene transfer using reversibly cross-linked low molecular weight polyethylenimine. Bioconjug. Chem. 2001, 12:989-994.
-
(2001)
Bioconjug. Chem.
, vol.12
, pp. 989-994
-
-
Gosselin, M.A.1
Guo, W.2
Lee, R.J.3
-
57
-
-
0033537026
-
Environment-sensitive stabilization of core-shell structured polyion complex micelle by reversible cross-linking of the core through disulfide bond
-
Kakizawa Y., Harada A., Kataoka K. Environment-sensitive stabilization of core-shell structured polyion complex micelle by reversible cross-linking of the core through disulfide bond. J. Am. Chem. Soc. 1999, 121:11247-11248.
-
(1999)
J. Am. Chem. Soc.
, vol.121
, pp. 11247-11248
-
-
Kakizawa, Y.1
Harada, A.2
Kataoka, K.3
-
58
-
-
58549112795
-
Environment-responsive block copolymer micelles with a disulfide cross-linked core for enhanced siRNA delivery
-
Matsumoto S., Christie R.J., Nishiyama N., Miyata K., Ishii A., Oba M., Koyama H., Yamasaki Y., Kataoka K. Environment-responsive block copolymer micelles with a disulfide cross-linked core for enhanced siRNA delivery. Biomacromolecules 2009, 10:119-127.
-
(2009)
Biomacromolecules
, vol.10
, pp. 119-127
-
-
Matsumoto, S.1
Christie, R.J.2
Nishiyama, N.3
Miyata, K.4
Ishii, A.5
Oba, M.6
Koyama, H.7
Yamasaki, Y.8
Kataoka, K.9
-
59
-
-
77950819407
-
Polymeric micelles with ionic cores containing biodegradable cross-links for delivery of chemotherapeutic agents
-
Kim J.O., Sahay G., Kabanov A.V., Bronich T.K. Polymeric micelles with ionic cores containing biodegradable cross-links for delivery of chemotherapeutic agents. Biomacromolecules 2010, 11:919-926.
-
(2010)
Biomacromolecules
, vol.11
, pp. 919-926
-
-
Kim, J.O.1
Sahay, G.2
Kabanov, A.V.3
Bronich, T.K.4
-
60
-
-
77956402895
-
Reversible interpolyelectrolyte shell cross-linked micelles from pH/salt-responsive diblock copolymers synthesized via RAFT in aqueous solution
-
Kellum M.G., Smith A.E., York S.K., McCormick C.L. Reversible interpolyelectrolyte shell cross-linked micelles from pH/salt-responsive diblock copolymers synthesized via RAFT in aqueous solution. Macromolecules 2010, 43:7033-7040.
-
(2010)
Macromolecules
, vol.43
, pp. 7033-7040
-
-
Kellum, M.G.1
Smith, A.E.2
York, S.K.3
McCormick, C.L.4
-
61
-
-
79952766615
-
Reversible imine shell cross-linked micelles from aqueous RAFT-synthesized thermoresponsive triblock copolymers as potential nanocarriers for "pH-Triggered" drug release
-
Xu X.W., Flores J.D., McCormick C.L. Reversible imine shell cross-linked micelles from aqueous RAFT-synthesized thermoresponsive triblock copolymers as potential nanocarriers for "pH-Triggered" drug release. Macromolecules 2011, 44:1327-1334.
-
(2011)
Macromolecules
, vol.44
, pp. 1327-1334
-
-
Xu, X.W.1
Flores, J.D.2
McCormick, C.L.3
-
62
-
-
80053165533
-
Interlayer-crosslinked micelle with partially hydrated core showing reduction and pH dual sensitivity for pinpointed intracellular drug release
-
Dai J., Lin S., Cheng D., Zou S., Shuai X. Interlayer-crosslinked micelle with partially hydrated core showing reduction and pH dual sensitivity for pinpointed intracellular drug release. Angew. Chem. Int. Ed. Engl. 2011, 50:9404-9408.
-
(2011)
Angew. Chem. Int. Ed. Engl.
, vol.50
, pp. 9404-9408
-
-
Dai, J.1
Lin, S.2
Cheng, D.3
Zou, S.4
Shuai, X.5
-
63
-
-
70749125578
-
Facile 'one-pot' preparation of reversible, disulfide-containing shell cross-linked micelles from a RAFT-synthesized, pH-responsive triblock copolymer in water at room temperature
-
Xu X.W., Smith A.E., McCormick C.L. Facile 'one-pot' preparation of reversible, disulfide-containing shell cross-linked micelles from a RAFT-synthesized, pH-responsive triblock copolymer in water at room temperature. Aust. J. Chem. 2009, 62:1520-1527.
-
(2009)
Aust. J. Chem.
, vol.62
, pp. 1520-1527
-
-
Xu, X.W.1
Smith, A.E.2
McCormick, C.L.3
-
64
-
-
25144505800
-
PH-responsive vesicles based on a hydrolytically self-cross-linkable copolymer
-
Du J., Armes S.P. pH-responsive vesicles based on a hydrolytically self-cross-linkable copolymer. J. Am. Chem. Soc. 2005, 127:12800-12801.
-
(2005)
J. Am. Chem. Soc.
, vol.127
, pp. 12800-12801
-
-
Du, J.1
Armes, S.P.2
-
65
-
-
80053997746
-
PH and reduction dual-sensitive copolymeric micelles for intracellular doxorubicin delivery
-
Chen J., Qiu X., Ouyang J., Kong J., Zhong W., Xing M.M. pH and reduction dual-sensitive copolymeric micelles for intracellular doxorubicin delivery. Biomacromolecules 2011, 12:3601-3611.
-
(2011)
Biomacromolecules
, vol.12
, pp. 3601-3611
-
-
Chen, J.1
Qiu, X.2
Ouyang, J.3
Kong, J.4
Zhong, W.5
Xing, M.M.6
-
66
-
-
40549133869
-
"Decoration" of shell cross-linked reverse polymer micelles using ATRP: a new route to stimuli-responsive nanoparticles
-
Babin J., Lepage M., Zhao Y. "Decoration" of shell cross-linked reverse polymer micelles using ATRP: a new route to stimuli-responsive nanoparticles. Macromolecules 2008, 41:1246-1253.
-
(2008)
Macromolecules
, vol.41
, pp. 1246-1253
-
-
Babin, J.1
Lepage, M.2
Zhao, Y.3
-
67
-
-
38649107346
-
Acid-degradable core-crosslinked micelles prepared from thermosensitive glycopolymers synthesized via RAFT polymerization
-
Zhang L., Bernard J., Davis T.P., Barner-Kowollik C., Stenzel M.H. Acid-degradable core-crosslinked micelles prepared from thermosensitive glycopolymers synthesized via RAFT polymerization. Macromol. Rapid Commun. 2008, 29:123-129.
-
(2008)
Macromol. Rapid Commun.
, vol.29
, pp. 123-129
-
-
Zhang, L.1
Bernard, J.2
Davis, T.P.3
Barner-Kowollik, C.4
Stenzel, M.H.5
-
68
-
-
0037167074
-
A detailed examination of boronic acid-diol complexation
-
Springsteen G., Wang B.H. A detailed examination of boronic acid-diol complexation. Tetrahedron 2002, 58:5291-5300.
-
(2002)
Tetrahedron
, vol.58
, pp. 5291-5300
-
-
Springsteen, G.1
Wang, B.H.2
-
69
-
-
31944449355
-
A structural investigation of the N-B interaction in an o-(N, N-dialkylaminomethyl)arylboronate system
-
Zhu L., Shabbir S.H., Gray M., Lynch V.M., Sorey S., Anslyn E.V. A structural investigation of the N-B interaction in an o-(N, N-dialkylaminomethyl)arylboronate system. J. Am. Chem. Soc. 2006, 128:1222-1232.
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 1222-1232
-
-
Zhu, L.1
Shabbir, S.H.2
Gray, M.3
Lynch, V.M.4
Sorey, S.5
Anslyn, E.V.6
-
70
-
-
27744603504
-
Preparation of organoboron block copolymers via ATRP of silicon and boron-functionalized monomers
-
Qin Y., Sukul V., Pagakos D., Cui C.Z., Jakle F. Preparation of organoboron block copolymers via ATRP of silicon and boron-functionalized monomers. Macromolecules 2005, 38:8987-8990.
-
(2005)
Macromolecules
, vol.38
, pp. 8987-8990
-
-
Qin, Y.1
Sukul, V.2
Pagakos, D.3
Cui, C.Z.4
Jakle, F.5
-
71
-
-
44049094022
-
Sugar-responsive block copolymers by direct RAFT polymerization of unprotected boronic acid monomers
-
Roy D., Cambre J.N., Sumerlin B.S. Sugar-responsive block copolymers by direct RAFT polymerization of unprotected boronic acid monomers. Chem. Commun. (Camb.) 2008, 2477-2479.
-
(2008)
Chem. Commun. (Camb.)
, pp. 2477-2479
-
-
Roy, D.1
Cambre, J.N.2
Sumerlin, B.S.3
-
72
-
-
33748175137
-
Polymer micelles with cross-linked ionic cores for delivery of anticancer drugs
-
Bontha S., Kabanov A.V., Bronich T.K. Polymer micelles with cross-linked ionic cores for delivery of anticancer drugs. J. Control. Release 2006, 114:163-174.
-
(2006)
J. Control. Release
, vol.114
, pp. 163-174
-
-
Bontha, S.1
Kabanov, A.V.2
Bronich, T.K.3
-
73
-
-
79960099888
-
Core cross-linked block ionomer micelles as pH-responsive carriers for cis-diamminedichloroplatinum(II)
-
Oberoi H.S., Laquer F.C., Marky L.A., Kabanov A.V., Bronich T.K. Core cross-linked block ionomer micelles as pH-responsive carriers for cis-diamminedichloroplatinum(II). J. Control. Release 2011, 153:64-72.
-
(2011)
J. Control. Release
, vol.153
, pp. 64-72
-
-
Oberoi, H.S.1
Laquer, F.C.2
Marky, L.A.3
Kabanov, A.V.4
Bronich, T.K.5
-
74
-
-
84870665846
-
Perspectives on clinical translation of smart nanotherapeutics
-
Lee J., Lam K.S. Perspectives on clinical translation of smart nanotherapeutics. Ther. Deliv. 2012, 3:1359-1362.
-
(2012)
Ther. Deliv.
, vol.3
, pp. 1359-1362
-
-
Lee, J.1
Lam, K.S.2
-
75
-
-
55049131168
-
Poly(amidoamine) conjugates with disulfide-linked cholesterol pendants self-assembling into redox-sensitive nanoparticles
-
Ranucci E., Suardi M.A., Annunziata R., Ferruti P., Chiellini F., Bartoli C. Poly(amidoamine) conjugates with disulfide-linked cholesterol pendants self-assembling into redox-sensitive nanoparticles. Biomacromolecules 2008, 9:2693-2704.
-
(2008)
Biomacromolecules
, vol.9
, pp. 2693-2704
-
-
Ranucci, E.1
Suardi, M.A.2
Annunziata, R.3
Ferruti, P.4
Chiellini, F.5
Bartoli, C.6
-
76
-
-
62549143061
-
Influence of Disulfide Density and Molecular Weight on Disulfide Cross-Linked Polyethylenimine as Gene Vectors
-
Peng Q., Hu C., Cheng J., Zhong Z.L., Zhuo R.X. Influence of Disulfide Density and Molecular Weight on Disulfide Cross-Linked Polyethylenimine as Gene Vectors. Bioconjug. Chem. 2009, 20:340-346.
-
(2009)
Bioconjug. Chem.
, vol.20
, pp. 340-346
-
-
Peng, Q.1
Hu, C.2
Cheng, J.3
Zhong, Z.L.4
Zhuo, R.X.5
-
77
-
-
1542306939
-
Block catiomer polyplexes with regulated densities of charge and disulfide cross-linking directed to enhance gene expression
-
Miyata K., Kakizawa Y., Nishiyama N., Harada A., Yamasaki Y., Koyama H., Kataoka K. Block catiomer polyplexes with regulated densities of charge and disulfide cross-linking directed to enhance gene expression. J. Am. Chem. Soc. 2004, 126:2355-2361.
-
(2004)
J. Am. Chem. Soc.
, vol.126
, pp. 2355-2361
-
-
Miyata, K.1
Kakizawa, Y.2
Nishiyama, N.3
Harada, A.4
Yamasaki, Y.5
Koyama, H.6
Kataoka, K.7
-
78
-
-
73649113198
-
Reduction-sensitive reversibly crosslinked biodegradable micelles for triggered release of doxorubicin
-
Xu Y., Meng F., Cheng R., Zhong Z. Reduction-sensitive reversibly crosslinked biodegradable micelles for triggered release of doxorubicin. Macromol. Biosci. 2009, 9:1254-1261.
-
(2009)
Macromol. Biosci.
, vol.9
, pp. 1254-1261
-
-
Xu, Y.1
Meng, F.2
Cheng, R.3
Zhong, Z.4
-
79
-
-
64649096911
-
Polyplex micelles with cyclic RGD peptide ligands and disulfide cross-links directing to the enhanced transfection via controlled intracellular trafficking
-
Oba M., Aoyagi K., Miyata K., Matsumoto Y., Itaka K., Nishiyama N., Yamasaki Y., Koyama H., Kataoka K. Polyplex micelles with cyclic RGD peptide ligands and disulfide cross-links directing to the enhanced transfection via controlled intracellular trafficking. Mol. Pharm. 2008, 5:1080-1092.
-
(2008)
Mol. Pharm.
, vol.5
, pp. 1080-1092
-
-
Oba, M.1
Aoyagi, K.2
Miyata, K.3
Matsumoto, Y.4
Itaka, K.5
Nishiyama, N.6
Yamasaki, Y.7
Koyama, H.8
Kataoka, K.9
-
80
-
-
52649117077
-
Formation of reversible shell cross-linked micelles from the biodegradable amphiphilic diblock copolymer poly(L-cysteine)-block-poly(L-lactide)
-
Sun J., Chen X., Lu T., Liu S., Tian H., Guo Z., Jing X. Formation of reversible shell cross-linked micelles from the biodegradable amphiphilic diblock copolymer poly(L-cysteine)-block-poly(L-lactide). Langmuir 2008, 24:10099-10106.
-
(2008)
Langmuir
, vol.24
, pp. 10099-10106
-
-
Sun, J.1
Chen, X.2
Lu, T.3
Liu, S.4
Tian, H.5
Guo, Z.6
Jing, X.7
-
81
-
-
67650458322
-
Temperature and pH double responsive hybrid cross-linked micelles based on P(NIPAAm-co-MPMA)-b-P(DEA): RAFT synthesis and "schizophrenic" micellization
-
Chang C., Wei H., Feng J., Wang Z.C., Wu X.J., Wu D.Q., Cheng S.X., Zhang X.Z., Zhuo R.X. Temperature and pH double responsive hybrid cross-linked micelles based on P(NIPAAm-co-MPMA)-b-P(DEA): RAFT synthesis and "schizophrenic" micellization. Macromolecules 2009, 42:4838-4844.
-
(2009)
Macromolecules
, vol.42
, pp. 4838-4844
-
-
Chang, C.1
Wei, H.2
Feng, J.3
Wang, Z.C.4
Wu, X.J.5
Wu, D.Q.6
Cheng, S.X.7
Zhang, X.Z.8
Zhuo, R.X.9
-
82
-
-
84886423792
-
Self-assembling nanoparticles containing dexamethasone as a novel therapy in allergic airways inflammation
-
Kenyon N.J., Bratt J.M., Lee J.S., Luo J., Franzi L.M., Zeki A.A., Lam K.S. Self-assembling nanoparticles containing dexamethasone as a novel therapy in allergic airways inflammation. PLOS one 2013.
-
(2013)
PLOS one
-
-
Kenyon, N.J.1
Bratt, J.M.2
Lee, J.S.3
Luo, J.4
Franzi, L.M.5
Zeki, A.A.6
Lam, K.S.7
|