Anti-obesity effect of Lactobacillus gasseri SBT2055 accompanied by inhibition of pro-inflammatory gene expression in the visceral adipose tissue in diet-induced obese mice

European Journal of Nutrition

Volumn 53, Issue 2, 2014, Pages 599-606

  Miyoshi, Masaya ^a   Ogawa, Akihiro ^a   Higurashi, Satoshi ^a   Kadooka, Yukio ^a  

^a SNOW BRAND MILK PRODUCTS CO LTD   (Japan)

Author keywords

Anti obesity; Gene expression; Inflammation; Metabolism; Mice; Probiotics

Indexed keywords

ACETYL COA CARBOXYLASE 1; ACETYL COENZYME A CARBOXYLASE; ANTIOBESITY AGENT; CHEMOKINE RECEPTOR CCR2; FAS ANTIGEN; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; SBT 2055; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA MICROARRAY; DRUG EFFECT; DRUG INHIBITION; EXPERIMENTAL OBESITY; GENE EXPRESSION; INTRAABDOMINAL FAT; LACTOBACILLUS GASSERI; LIPID LIVER LEVEL; MALE; MOUSE; NONHUMAN; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WEIGHT REDUCTION;

LACTOBACILLUS GASSERI; MUS;

ADIPOSITY; ANIMALS; BODY COMPOSITION; BODY WEIGHT; CHEMOKINE CCL2; DIET; DIETARY FATS; EPIDIDYMIS; FATTY ACID SYNTHASES; GENE EXPRESSION REGULATION; INFLAMMATION; INTRA-ABDOMINAL FAT; LACTOBACILLUS; LIPID METABOLISM; LIVER; MALE; MICE; MICE, INBRED C57BL; OBESITY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROBIOTICS; RNA, MESSENGER; TRIGLYCERIDES;

EID: 84896691358     PISSN: 14366207     EISSN: 14366215     Source Type: Journal    
DOI: 10.1007/s00394-013-0568-9     Document Type: Article

References (50)

1. WHO (2012) WHO | obesity and overweight. http://www.who.int/mediacentre/ factsheets/fs311/en/index.html. Accessed 21 Feb 2013
2. Fox CS, Massaro JM, Hoffmann U et al (2007) Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham heart study. Circulation 116:39-48
3. Ford ES, Williamson DF, Liu S (1997) Weight change and diabetes incidence: findings from a national cohort of US adults. Am J Epidemiol 146:214-222
4. Liu B, Balkwill A, Reeves G, Beral V (2010) Body mass index and risk of liver cirrhosis in middle aged UK women: prospective study. BMJ 340:c912
5. Hubert HB, Feinleib M, McNamara PM, Castelli WP (1983) Obesity as an independent risk factor for cardiovascular disease: a 26-year follow-up of participants in the Framingham heart study. Circulation 67:968-977
6. Huffman D, Barzilai N (2009) Role of visceral adipose tissue in aging. Biochim Biophys Acta 1790:1117-1123
7. Gupta A, Gupta V (2010) Metabolic syndrome: what are the risks for humans? Biosci Trends 4:204-212
8. Horton ES (2009) Effects of lifestyle changes to reduce risks of diabetes and associated cardiovascular risks: results from large scale efficacy trials. Obesity (Silver Spring) 17(Suppl 3):S43-S48
9. Thomas CM, Versalovic J (2010) Probiotics-host communication: modulation of signaling pathways in the intestine. Gut microbes 1:148-163
10. Lye HS, Kuan CY, Ewe JA, Fung WY, Liong MT (2009) The improvement of hypertension by probiotics: effects on cholesterol, diabetes, renin, and phytoestrogens. Int J Mol Sci 10:3755-3775
11. Mallappa RH, Rokana N, Duary RK, Panwar H, Batish VK, Grover S (2012) Management of metabolic syndrome through probiotic and prebiotic interventions. Indian J Endocrinol Metab 16:20-27
12. Lee HY, Park JH, Seok SH, Baek MW, Kim DJ, Lee KE, Paek KS, Lee Y, Park JH (2006) Human originated bacteria, Lactobacillus rhamnosus PL60, produce conjugated linoleic acid and show anti-obesity effects in diet-induced obese mice. Biochim Biophys Acta 1761:736-744
13. Lee K, Paek K, Lee HY, Park JH, Lee Y (2007) Antiobesity effect of trans-10, cis-12-conjugated linoleic acid-producing Lactobacillus plantarum PL62 on diet-induced obese mice. J Appl Microbiol 103:1140-1146
14. Kondo S, Xiao J, Satoh T, Odamaki T, Takahashi S, Sugahara H, Yaeshima T, Iwatsuki K, Kamei A, Abe K (2010) Antiobesity effects of Bifidobacterium breve strain b-3 supplementation in a mouse model with high-fat diet-induced obesity. Biosci Biotechnol Biochem 74:1656-1661
15. Aronsson L, Huang Y, Parini P, Korach-André M, Håkansson J, Gustafsson J-Å, Pettersson S, Arulampalam V, Rafter J (2010) Decreased fat storage by Lactobacillus paracasei is associated with increased levels of angiopoietin-like 4 protein (ANGPTL4). PLoS One 5:e13087
16. Sato M, Uzu K, Yoshida T, Hamad EM, Kawakami H, Matsuyama H, Abd El-Gawad IA, Imaizumi K (2008) Effects of milk fermented by Lactobacillus gasseri SBT2055 on adipocyte size in rats. Br J Nutr 99:1013-1017
17. Hamad EM, Sato M, Uzu K, Yoshida T, Higashi S, Kawakami H, Kadooka Y, Matsuyama H, Abd El-Gawad IA, Imaizumi K (2009) Milk fermented by Lactobacillus gasseri SBT2055 influences adipocyte size via inhibition of dietary fat absorption in Zucker rats. Br J Nutr 101:716-724
18. Kadooka Y, Ogawa A, Ikuyama K, Sato M (2011) The probiotic Lactobacillus gasseri SBT2055 inhibits enlargement of visceral adipocytes and upregulation of serum soluble adhesion molecule (sICAM-1) in rats. Int Dairy J 21:623-627
19. Kadooka Y, Sato M, Imaizumi K, Ogawa A, Ikuyama K, Akai Y, Okano M, Kagoshima M, Tsuchida T (2010) Regulation of abdominal adiposity by probiotics (Lactobacillus gasseri SBT2055) in adults with obese tendencies in a randomized controlled trial. Eur J Clin Nutr 64:636-643
20. Fujiwara S, Seto Y, Kimura A, Hashiba H (2001) Establishment of orally-administered Lactobacillus gasseri SBT2055SR in the gastrointestinal tract of humans and its influence on intestinal microflora and. J Appl Microbiol 90:343-352
21. Imai E, Fukui K, Ohta N, Tomitsuka T (2002) Effects of Lactobacillus gasseri SBT2055 on dextran sulfate sodium-induced ulcerative colitis model in rats. Biosci Microflora 21:179-183
22. Bastard J, Maachi M, Lagathu C, Kim MJ, Caron M, Vidal H, Capeau J, Feve B (2006) Recent advances in the relationship between obesity, inflammation, and insulin resistance. Eur Cytokine Netw 17:4-12
23. Hotamisligil GS (2006) Inflammation and metabolic disorders. Nature 444:860-867
24. Ding S, Chi MM, Scull BP, Rigby R, Schwerbrock NMJ, Magness S, Jobin C, Lund PK (2010) High-fat diet: bacteria interactions promote intestinal inflammation which precedes and correlates with obesity and insulin resistance in mouse. PLoS One 5:e12191
25. Cani PD, Amar J, Iglesias MA et al (2007) Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes 56:1761-1772
26. Yang ZH, Miyahara H, Takeo J, Katayama M (2012) Diet high in fat and sucrose induces rapid onset of obesity-related metabolic syndrome partly through rapid response of genes involved in lipogenesis, insulin signalling and inflammation in mice. Diabetol Metab Syndr 4:32
27. American Institute of Nutrition (1977) Report of the American Institute of Nutrition ad hoc committee on standards for nutritional studies. J Nutr 107:1340-1348
28. Folch J, Lees M, Sloane-Stanley G (1957) A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226:497-509
29. Lumeng CN, Bodzin JL, Saltiel AR (2007) Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest 117:175-184
30. Kanda H, Tateya S, Tamori Y et al (2006) MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity. J Clin Invest 116:1494-1505
31. Weisberg S, Hunter D, Huber R, Lemieux J, Slaymaker S, Vaddi K, Charo I, Leibel RL, Ferrante AWJ (2006) CCR2 modulates inflammatory and metabolic effects of high-fat feeding. J Clin Invest 116:115-124
32. Wellen K, Hotamisligil G (2003) Obesity-induced inflammatory changes in adipose tissue. J Clin Invest 112:1785-1788
33. Suganami T, Nishida J, Ogawa Y (2005) A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha. Arterioscler Thromb Vasc Biol 25:2062-2068
34. Shoelson SSE, Lee J, Goldfine AB (2006) Inflammation and insulin resistance. J Clin Invest 116:1793-1801
35. Tamura Y, Sugimoto M, Murayama T, Minami M, Nishikaze Y, Ariyasu H, Akamizu T, Kita T, Yokode M, Arai H (2010) C-C chemokine receptor 2 inhibitor improves diet-induced development of insulin resistance and hepatic steatosis in mice. J Atheroscler Thromb 17:219-228
36. Li H, Lelliott C, Håkansson P, Ploj K, Tuneld A, Verolin-Johansson M, Benthem L, Carlsson B, Storlien L, Michaëlsson E (2008) Intestinal, adipose, and liver inflammation in diet-induced obese mice. Metabolism 57:1704-1710
37. DeLany JP, Windhauser MM, Champagne CM, Bray GA (2000) Differential oxidation of individual dietary fatty acids in humans. Am J Clin Nutr 72:905-911
38. Tjonneland A, Overvad K, Bergmann MM et al (2009) Linoleic acid, a dietary n-6 polyunsaturated fatty acid, and the aetiology of ulcerative colitis: a nested case-control study within a European prospective cohort study. Gut 58:1606-1611
39. Postic C, Girard J (2008) Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice. J Clin Invest 118:829-838
40. Mao J, DeMayo FJ, Li H, Abu-Elheiga L, Gu Z, Shaikenov TE, Kordari P, Chirala SS, Heird WC, Wakil SJ (2006) Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis. Proc Natl Acad Sci USA 103:8552-8557
41. Ntambi JM, Miyazaki M, Stoehr JP, Lan H, Kendziorski CM, Yandell BS, Song Y, Cohen P, Friedman JM, Attie AD (2002) Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity. Proc Natl Acad Sci USA 99:11482-11486
42. Jiang G, Li Z, Liu F et al (2005) Prevention of obesity in mice by antisense oligonucleotide inhibitors of stearoyl-CoA desaturase-1. J Clin Invest 115:1030-1038
43. Guerre-Millo M, Gervois P (2000) Peroxisome proliferator-activated receptor α activators improve insulin sensitivity and reduce adiposity. J Biol Chem 275:16638-16642
44. Donnelly KL, Smith CI, Schwarzenberg SJ, Jessurun J, Boldt MD, Parks EJ (2005) Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J Clin Invest 115:1343-1351
45. Sanal MG (2008) The blind men "see" the elephant-the many faces of fatty liver disease. World J Gastroenterol 14:831-844
46. Gibbons GF (1990) Assembly and secretion of hepatic very-low-density lipoprotein. Biochem J 268:1-13
47. Wolfe RR, Durkot MJ (1985) Role of very low density lipoproteins in the energy metabolism of the rat. J Lipid Res 26:210-217
48. Raabe M, Véniant MM, Sullivan MA, Zlot CH, Björkegren J, Nielsen LB, Wong JS, Hamilton RL, Young SG (1999) Analysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice. J Clin Invest 103:1287-1298
49. Hoffmann M, Rath E, Hölzlwimmer G, Quintanilla-Martinez L, Loach D, Tannock G, Haller D (2008) Lactobacillus reuteri 100-23 transiently activates intestinal epithelial cells of mice that have a complex microbiota during early stages of colonization. J Nutr 138:1684-1691
50. Li N, Russell WM, Douglas-escobar M, Hauser N, Lopez M, Neu J (2009) Live and heat-killed Lactobacillus rhamnosus GG: effects on proinflammatory and anti-inflammatory cytokines/chemokines in gastrostomy-fed infant rats. Pediatr Res 66:203-207