Induction of Matrix Metalloproteinase-3 (MMP-3) Expression in the Microglia by Lipopolysaccharide (LPS) via Upregulation of Glycoprotein Nonmetastatic Melanoma B (GPNMB) Expression

Journal of Molecular Neuroscience

Volumn 54, Issue 2, 2014, Pages 234-242

  Shi, Fangyuan ^a   Duan, Shuangyan ^b   Cui, Jihong ^a   Yan, Xingrong ^a   Li, Hongmin ^a   Wang, Yingjuan ^a   Chen, Fulin ^a   Zhang, Lihua ^c   Liu, Jun ^c   Xie, Xin ^a,b  

^a NORTHWEST UNIVERSITY   (China)

^b Institute of Integrated Medical Information (IMI)   (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Glycoprotein nonmetastatic melanoma B; Lipopolysaccharide; Matrix metalloproteinase 3; Microglia

Indexed keywords

EYE PROTEIN; GPNMB PROTEIN, MOUSE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MEMBRANE PROTEIN; MMP3 PROTEIN, MOUSE; STROMELYSIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; CELL LINE; DRUG EFFECTS; GENETICS; METABOLISM; MICROGLIA; MOUSE; UPREGULATION;

ANIMALS; CELL LINE; EYE PROTEINS; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MATRIX METALLOPROTEINASE 3; MEMBRANE GLYCOPROTEINS; MICE; MICROGLIA; NITRIC OXIDE SYNTHASE TYPE II; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 84896689249     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-014-0280-0     Document Type: Article

References (28)

1. Carvey PM, Chang Q, Lipton JW, Ling Z (2003) Prenatal exposure to the bacteriotoxin lipopolysaccharide leads to long-term losses of dopamine neurons in offspring: a potential, new model of Parkinson’s disease. Frontiers in bioscience: a journal and virtual library 8:s826–s837
2. Chung J-S, Sato K, Dougherty II, Cruz PD, Ariizumi K (2007) DC-HIL is a negative regulator of T lymphocyte activation. Blood 109:4320–4327
3. Furochi H, Tamura S, Mameoka M, Yamada C, Ogawa T, Hirasaka K, Okumura Y, Imagawa T, Oguri S, Ishidoh K (2007) Osteoactivin fragments produced by ectodomain shedding induce MMP-3 expression via ERK pathway in mouse NIH-3T3 fibroblasts. FEBS letters 581:5743–5750
4. Gao HM, Jiang J, Wilson B, Zhang W, Hong JS, Liu B (2002) Microglial activation‐mediated delayed and progressive degeneration of rat nigral dopaminergic neurons: relevance to Parkinson’s disease. J Neurochem 81:1285–1297
5. Griffin W, Stanley L, Ling C, White L, MacLeod V, Perrot L, White C, Araoz C (1989) Brain interleukin 1 and S-100 immunoreactivity are elevated in down syndrome and Alzheimer disease. Proc Natl Acad Sci 86:7611–7615
6. Hinkerohe D, Smikalla D, Schoebel A, Haghikia A, Zoidl G, Haase CG, Schlegel U, Faustmann PM (2010) Dexamethasone prevents LPS-induced microglial activation and astroglial impairment in an experimental bacterial meningitis co-culture model. Brain research 1329:45–54
7. Huang JJ, Ma WJ, Yokoyama S (2012) Expression and immunolocalization of Gpnmb, a glioma‐associated glycoprotein, in normal and inflamed central nervous systems of adult rats. Brain and behavior 2:85–96
8. Kuan CT, Wakiya K, Keir ST, Li J, Herndon JE, Pastan I, Bigner DD (2011) Affinity‐matured anti‐glycoprotein NMB recombinant immunotoxins targeting malignant gliomas and melanomas. Int J Cancer 129:111–121
9. Liu B, Hong J-S (2003) Role of microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention. J Pharmacol Exp Ther 304:1–7
10. Livak, K., Schmittgen, T. (2009) Analysis of relative gene expression data using real-time quantitative PCR and the 2 −Delta Delta C (T) Method. Methods. 2001; 25 (4): 402–408. View this article via: PubMed CrossRef.
11. Lull ME, Block ML (2010) Microglial activation and chronic neurodegeneration. Neurotherapeutics 7:354–365
12. McDonald DR, Brunden KR, Landreth GE (1997) Amyloid fibrils activate tyrosine kinase-dependent signaling and superoxide production in microglia. J Neurosci 17:2284–2294
13. Minghetti L, Levi G (1998) Microglia as effector cells in brain damage and repair: focus on prostanoids and nitric oxide. Prog Neurobiol 54:99–125
14. Mun-Bryce S, Lukes A, Wallace J, Lukes-Marx M, Rosenberg GA (2002) Stromelysin-1 and gelatinase a are upregulated before TNF-α in LPS-stimulated neuroinflammation. Brain research 933:42–49
15. Nuttall RK, Silva C, Hader W, Bar‐Or A, Patel KD, Edwards DR, Yong VW (2007) Metalloproteinases are enriched in microglia compared with leukocytes and they regulate cytokine levels in activated microglia. Glia 55:516–526
16. Ogawa T, Nikawa T, Furochi H, Kosyoji M, Hirasaka K, Suzue N, Sairyo K, Nakano S, Yamaoka T, Itakura M (2005) Osteoactivin upregulates expression of MMP-3 and MMP-9 in fibroblasts infiltrated into denervated skeletal muscle in mice. Am J Physiol Cell Physiol 289:C697–C707
17. Owen, T.A., Smock, S.L., Prakash, S., Pinder, L., Brees, D., Krull, D., Castleberry, T., Clancy, Y., Marks Jr, S.C., Safadi, F.F. (2003) Identification and characterization of the genes encoding human and mouse osteoactivin. Critical Reviews™ in Eukaryotic Gene Expression. 13.
18. Pahl MV, Vaziri ND, Yuan J, Adler SG (2010) Upregulation of monocyte/macrophage HGFIN (Gpnmb/Osteoactivin) expression in end-stage renal disease. Clin J Am Soc Nephrol 5:56–61
19. Perry VH, Nicoll JA, Holmes C (2010) Microglia in neurodegenerative disease. Nat Rev Neurol 6:193–201
20. Punturee K, Wild CP, Vinitketkumneun U (2004) Thai medicinal plants modulate nitric oxide and tumor necrosis factor-α in J774. 2 mouse macrophages. J Ethnopharmacol 95:183–189
21. Qin L, Block ML, Liu Y, Bienstock RJ, Pei Z, Zhang W, Wu X, Wilson B, Burka T, Hong J-S (2005) Microglial NADPH oxidase is a novel target for femtomolar neuroprotection against oxidative stress. FASEB J 19:550–557
22. Rich JN, Shi Q, Hjelmeland M, Cummings TJ, Kuan C-T, Bigner DD, Counter CM, Wang X-F (2003) Bone-related genes expressed in advanced malignancies induce invasion and metastasis in a genetically defined human cancer model. J Biol Chem 278:15951–15957
23. Ripoll VM, Irvine KM, Ravasi T, Sweet MJ, Hume DA (2007) Gpnmb is induced in macrophages by IFN-γ and lipopolysaccharide and acts as a feedback regulator of proinflammatory responses. J Immunol 178:6557–6566
24. Rose AA, Siegel PM (2010) Emerging therapeutic targets in breast cancer bone metastasis. Future Oncol 6:55–74
25. Tanaka, H., Shimazawa, M., Kimura, M., Takata, M., Tsuruma, K., Yamada, M., Takahashi, H., Hozumi, I., Niwa, J.-i., Iguchi, Y. (2012) The potential of GPNMB as novel neuroprotective factor in amyotrophic lateral sclerosis. Scientific reports. 2.
26. Westermarck J, KÄHÄRI V-M (1999) Regulation of matrix metalloproteinase expression in tumor invasion. FASEB J 13:781–792
27. Weterman MAJ, Ajubi N, van Dinter IMR, Degen WGJ, van Muijen GNP, Ruiter DJ, Bloemers HPJ (1995) nmb, a novel gene, is expressed in low鈥恗etastatic human melanoma cell lines and xenografts. Int J cancer 60:73–81
28. Woo MS, Park JS, Choi IY, Kim WK, Kim HS (2008) Inhibition of MMP‐3 or‐9 suppresses lipopolysaccharide‐induced expression of proinflammatory cytokines and iNOS in microglia. J Neurochem 106:770–780