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Volumn 43, Issue 3, 2014, Pages 470-477

Increased intratumoral interleukin 22 levels and frequencies of interleukin 22-producing CD4+ T cells correlate with pancreatic cancer progression

Author keywords

Pancreatic cancer; STAT 3

Indexed keywords

CYCLIN D1; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 22; PROTEIN BCL 2; STAT3 PROTEIN; INTERLEUKIN DERIVATIVE; INTERLEUKIN-22;

EID: 84896688553     PISSN: 08853177     EISSN: 15364828     Source Type: Journal    
DOI: 10.1097/MPA.0000000000000055     Document Type: Article
Times cited : (33)

References (36)
  • 2
    • 79960117061 scopus 로고    scopus 로고
    • Environmental risk factors for chronic pancreatitis and pancreatic cancer
    • Nitsche C, Simon P, Weiss FU, et al. Environmental risk factors for chronic pancreatitis and pancreatic cancer. Dig Dis. 2011;29:235-242.
    • (2011) Dig Dis , vol.29 , pp. 235-242
    • Nitsche, C.1    Simon, P.2    Weiss, F.U.3
  • 3
    • 33645907503 scopus 로고    scopus 로고
    • Inflammation and cancer: The role of the immune response and angiogenesis
    • Dalgleish AG, O'Byrne K. Inflammation and cancer: The role of the immune response and angiogenesis. Cancer Treat Res. 2006;130:1-38.
    • (2006) Cancer Treat Res , vol.130 , pp. 1-38
    • Dalgleish, A.G.1    O'Byrne, K.2
  • 4
    • 34248141100 scopus 로고    scopus 로고
    • A cytokine-mediated link between innate immunity, inflammation, and cancer
    • Lin WW, Karin M. A cytokine-mediated link between innate immunity, inflammation, and cancer. J Clin Invest. 2007;117:1175-1183.
    • (2007) J Clin Invest , vol.117 , pp. 1175-1183
    • Lin, W.W.1    Karin, M.2
  • 5
    • 78649757427 scopus 로고    scopus 로고
    • Interleukin-22: A cytokine produced by T, NK and NKT cell subsets, with importance in the innate immune defense and tissue protection
    • Witte E, Witte K, Warszawska K, et al. Interleukin-22: A cytokine produced by T, NK and NKT cell subsets, with importance in the innate immune defense and tissue protection. Cytokine Growth Factor Rev. 2010;21:365-379.
    • (2010) Cytokine Growth Factor Rev , vol.21 , pp. 365-379
    • Witte, E.1    Witte, K.2    Warszawska, K.3
  • 6
    • 51349156105 scopus 로고    scopus 로고
    • IL-22R, IL-10-2, and IL-22BP binding sites are topologically juxtaposed on adjacent and overlapping surfaces of IL-22
    • Wu PW, Li J, Kodangattil SR, et al. IL-22R, IL-10-2, and IL-22BP binding sites are topologically juxtaposed on adjacent and overlapping surfaces of IL-22. J Mol Biol. 2008;382:1168-1183.
    • (2008) J Mol Biol , vol.382 , pp. 1168-1183
    • Wu, P.W.1    Li, J.2    Kodangattil, S.R.3
  • 7
    • 2342462460 scopus 로고    scopus 로고
    • Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation
    • Radaeva S, Sun R, Pan HN, et al. Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation. Hepatology. 2004;39:1332-1342.
    • (2004) Hepatology , vol.39 , pp. 1332-1342
    • Radaeva, S.1    Sun, R.2    Pan, H.N.3
  • 8
    • 77958489808 scopus 로고    scopus 로고
    • Functional biology of the IL-22YIL-22r pathway in regulating immunity and inflammation at barrier surfaces
    • Sonnenberg GF, Fouser LA, Artis D. Functional biology of the IL-22YIL-22r pathway in regulating immunity and inflammation at barrier surfaces. Adv Immunol. 2010;107:1-29.
    • (2010) Adv Immunol , vol.107 , pp. 1-29
    • Sonnenberg, G.F.1    Fouser, L.A.2    Artis, D.3
  • 9
    • 2142717328 scopus 로고    scopus 로고
    • Interleukin-22 activates STAT3 and induces IL-10 by colon epithelial cells
    • Nagalakshmi ML, Rascle A, Zurawski S, et al. Interleukin-22 activates STAT3 and induces IL-10 by colon epithelial cells. Int Immunopharmacal. 2004;4:679-691.
    • (2004) Int Immunopharmacal , vol.4 , pp. 679-691
    • Nagalakshmi, M.L.1    Rascle, A.2    Zurawski, S.3
  • 10
    • 79952217505 scopus 로고    scopus 로고
    • Protective properties of inhaled IL-22 in a model of ventilator-induced lung injury
    • Hoegl S, Bachmann M, Scheiermann P, et al. Protective properties of inhaled IL-22 in a model of ventilator-induced lung injury. Am J Resp Cell Mol. 2011;44:369-376.
    • (2011) Am J Resp Cell Mol , vol.44 , pp. 369-376
    • Hoegl, S.1    Bachmann, M.2    Scheiermann, P.3
  • 11
    • 45549092326 scopus 로고    scopus 로고
    • Interleukin 22 receptor 1 expression in pancreas islets
    • Shioya M, Andoh A, Kakinoki S, et al. Interleukin 22 receptor 1 expression in pancreas islets. Pancreas. 2008;36:197-199.
    • (2008) Pancreas , vol.36 , pp. 197-199
    • Shioya, M.1    Andoh, A.2    Kakinoki, S.3
  • 12
    • 0037072796 scopus 로고    scopus 로고
    • Interleukin-22 (IL-22) activates the JAK/STAT, ERK, JNK, and p38 MAP kinase pathways in a rat hepatoma cell line. Pathways that are shared with and distinct from IL-10
    • Lejeune D, Dumoutier L, Constantinescu S, et al. Interleukin-22 (IL-22) activates the JAK/STAT, ERK, JNK, and p38 MAP kinase pathways in a rat hepatoma cell line. Pathways that are shared with and distinct from IL-10. J Biol Chem. 2002;277:33676-33682.
    • (2002) J Biol Chem , vol.277 , pp. 33676-33682
    • Lejeune, D.1    Dumoutier, L.2    Constantinescu, S.3
  • 13
    • 33845865825 scopus 로고    scopus 로고
    • Crosstalk between cancer and immune cells: Role of STAT3 in the tumour microenvironment
    • Yu H, Kortylewski M, Pardoll D. Crosstalk between cancer and immune cells: Role of STAT3 in the tumour microenvironment. Nat Rev Immunol. 2007;7:41-51.
    • (2007) Nat Rev Immunol , vol.7 , pp. 41-51
    • Yu, H.1    Kortylewski, M.2    Pardoll, D.3
  • 14
    • 78650859531 scopus 로고    scopus 로고
    • NF-kappab and STAT3 - key players in liver inflammation and cancer
    • He G, Karin M. NF-kappab and STAT3 - key players in liver inflammation and cancer. Cell Res. 2011;21:159-168.
    • (2011) Cell Res , vol.21 , pp. 159-168
    • He, G.1    Karin, M.2
  • 15
    • 35348983341 scopus 로고    scopus 로고
    • Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation
    • Zenewicz LA, Yancopoulos GD, Valenzuela DM, et al. Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation. Immunity. 2007;27:647-659.
    • (2007) Immunity , vol.27 , pp. 647-659
    • Zenewicz, L.A.1    Yancopoulos, G.D.2    Valenzuela, D.M.3
  • 16
    • 80052023399 scopus 로고    scopus 로고
    • Interleukin-22 promotes human hepatocellular carcinoma by activation of STAT3
    • Jiang R, Tan Z, Deng L, et al. Interleukin-22 promotes human hepatocellular carcinoma by activation of STAT3. Hepatology. 2011;54:900-909.
    • (2011) Hepatology , vol.54 , pp. 900-909
    • Jiang, R.1    Tan, Z.2    Deng, L.3
  • 17
    • 77956494792 scopus 로고    scopus 로고
    • IL-22Yproducing CD4+ T cells: Middle-men between the immune system and its environment
    • Trifari S, Spits H. IL-22Yproducing CD4+ T cells: Middle-men between the immune system and its environment. Eur J Immunol. 2010;40:2369-2371.
    • (2010) Eur J Immunol , vol.40 , pp. 2369-2371
    • Trifari, S.1    Spits, H.2
  • 18
    • 67649161002 scopus 로고    scopus 로고
    • IL-22Yproducing ''t22 T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17Yproducing TH17 T cells
    • e1242
    • Nograles KE, Zaba LC, Shemer A, et al. IL-22Yproducing ''t22'' T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17Yproducing TH17 T cells. J Allergy Clin Immun. 2009;123:1244-1252 e1242.
    • (2009) J Allergy Clin Immun , vol.123 , pp. 1244-1252
    • Nograles, K.E.1    Zaba, L.C.2    Shemer, A.3
  • 19
    • 76049091500 scopus 로고    scopus 로고
    • Human langerhans cells induce distinct IL-22Yproducing CD4+ T cells lacking IL-17 production
    • Fujita H, Nograles KE, Kikuchi T, et al. Human langerhans cells induce distinct IL-22Yproducing CD4+ T cells lacking IL-17 production. P Natl Acan SCI USA. 2009;106:21795-21800.
    • (2009) P Natl Acan SCI USA , vol.106 , pp. 21795-21800
    • Fujita, H.1    Nograles, K.E.2    Kikuchi, T.3
  • 20
    • 0036604122 scopus 로고    scopus 로고
    • Cutting edge Immune cells as sources and targets of the IL-10 family members?
    • Wolk K, Kunz S, Asadullah K, et al. Cutting edge: Immune cells as sources and targets of the IL-10 family members?. J Immunol. 2002;168:5397-5402.
    • (2002) J Immunol , vol.168 , pp. 5397-5402
    • Wolk, K.1    Kunz, S.2    Asadullah, K.3
  • 21
    • 33751120140 scopus 로고    scopus 로고
    • Expression and regulation of IL-22 in the IL-17Yproducing CD4+ T lymphocytes
    • Chung Y, Yang X, Chang SH, et al. Expression and regulation of IL-22 in the IL-17Yproducing CD4+ T lymphocytes. Cell Res. 2006;16:902-907.
    • (2006) Cell Res , vol.16 , pp. 902-907
    • Chung, Y.1    Yang, X.2    Chang, S.H.3
  • 22
    • 33846906224 scopus 로고    scopus 로고
    • Interleukin-22, a t(h)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
    • Zheng Y, Danilenko DM, Valdez P, et al. Interleukin-22, a t(h)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis. Nature. 2007;445:648-651.
    • (2007) Nature , vol.445 , pp. 648-651
    • Zheng, Y.1    Danilenko, D.M.2    Valdez, P.3
  • 23
    • 67651154105 scopus 로고    scopus 로고
    • Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells
    • Duhen T, Geiger R, Jarrossay D, et al. Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells. Nat Immunol. 2009;10:857-863.
    • (2009) Nat Immunol , vol.10 , pp. 857-863
    • Duhen, T.1    Geiger, R.2    Jarrossay, D.3
  • 24
    • 72849131815 scopus 로고    scopus 로고
    • TH22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling
    • Eyerich S, Eyerich K, Pennino D, et al. TH22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling. J Clin Invest. 2009;119:3573-3585.
    • (2009) J Clin Invest , vol.119 , pp. 3573-3585
    • Eyerich, S.1    Eyerich, K.2    Pennino, D.3
  • 25
    • 67651171182 scopus 로고    scopus 로고
    • Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from t(h)-17, t(h)1 and t(h)2 cells
    • Trifari S, Kaplan CD, Tran EH, et al. Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from t(h)-17, t(h)1 and t(h)2 cells. Nat Immunol. 2009;10:864-871.
    • (2009) Nat Immunol , vol.10 , pp. 864-871
    • Trifari, S.1    Kaplan, C.D.2    Tran, E.H.3
  • 26
    • 77951091571 scopus 로고    scopus 로고
    • Circulating TH17, TH22, and TH1 cells are increased in psoriasis
    • Kagami S, Rizzo HL, Lee JJ, et al. Circulating TH17, TH22, and TH1 cells are increased in psoriasis. J Invest Dermatol. 2010;130:1373-1383.
    • (2010) J Invest Dermatol , vol.130 , pp. 1373-1383
    • Kagami, S.1    Rizzo, H.L.2    Lee, J.J.3
  • 27
    • 80555150814 scopus 로고    scopus 로고
    • Elevated TH22 cells correlated with TH17 cells in patients with rheumatoid arthritis
    • Zhang L, Li JM, Liu XG, et al. Elevated TH22 cells correlated with TH17 cells in patients with rheumatoid arthritis. J Clin Immunol. 2011;31:606-614.
    • (2011) J Clin Immunol , vol.31 , pp. 606-614
    • Zhang, L.1    Li, J.M.2    Liu, X.G.3
  • 28
    • 84871018340 scopus 로고    scopus 로고
    • Increased intratumoral IL-22Yproducing CD4(+) T cells and TH22 cells correlate with gastric cancer progression and predict poor patient survival
    • Zhuang Y, Peng LS, Zhao YL, et al. Increased intratumoral IL-22Yproducing CD4(+) T cells and TH22 cells correlate with gastric cancer progression and predict poor patient survival. Cancer Immunol ImmunI. 2012;61(11):1965-1975.
    • (2012) Cancer Immunol ImmunI , vol.61 , Issue.11 , pp. 1965-1975
    • Zhuang, Y.1    Peng, L.S.2    Zhao, Y.L.3
  • 29
    • 84859244400 scopus 로고    scopus 로고
    • Pro-Tumour activity of interleukin-22 in hpafii human pancreatic cancer cells
    • Curd LM, Favors SE, Gregg RK. Pro-Tumour activity of interleukin-22 in hpafii human pancreatic cancer cells. Clin Exp Immunol. 2012;168:192-199.
    • (2012) Clin Exp Immunol , vol.168 , pp. 192-199
    • Curd, L.M.1    Favors, S.E.2    Gregg, R.K.3
  • 31
    • 4143095716 scopus 로고    scopus 로고
    • IL-22 increases the innate immunity of tissues
    • Wolk K, Kunz S, Witte E, et al. IL-22 increases the innate immunity of tissues. Immunity. 2004;21:241-254.
    • (2004) Immunity , vol.21 , pp. 241-254
    • Wolk, K.1    Kunz, S.2    Witte, E.3
  • 32
    • 77953128344 scopus 로고    scopus 로고
    • Serum IL-22 correlates with psoriatic severity and serum IL-6 correlates with susceptibility to phototherapy
    • Lo YH, Torii K, Saito C, et al. Serum IL-22 correlates with psoriatic severity and serum IL-6 correlates with susceptibility to phototherapy. J Dermatol Sci. 2010;58:225-227.
    • (2010) J Dermatol Sci , vol.58 , pp. 225-227
    • Lo, Y.H.1    Torii, K.2    Saito, C.3
  • 33
    • 2142659288 scopus 로고    scopus 로고
    • IL-22, a TH1 cytokine that targets the pancreas and select other peripheral tissues
    • Gurney AL. IL-22, a TH1 cytokine that targets the pancreas and select other peripheral tissues. Int Immunopharmacol. 2004;4:669-677.
    • (2004) Int Immunopharmacol , vol.4 , pp. 669-677
    • Gurney, A.L.1
  • 34
    • 40049103352 scopus 로고    scopus 로고
    • IL-22 is expressed by TH17 cells in an IL-23Ydependent fashion, but not required for the development of autoimmune encephalomyelitis
    • Kreymborg K, Etzensperger R, Dumoutier L, et al. IL-22 is expressed by TH17 cells in an IL-23Ydependent fashion, but not required for the development of autoimmune encephalomyelitis. J Immunol. 2007;179:8098-8104.
    • (2007) J Immunol , vol.179 , pp. 8098-8104
    • Kreymborg, K.1    Etzensperger, R.2    Dumoutier, L.3
  • 35
    • 77951755278 scopus 로고    scopus 로고
    • Pancreatic cancer
    • Hidalgo M. Pancreatic cancer. N Engl J Med. 2010;362:1605-1617.
    • (2010) N Engl J Med , vol.362 , pp. 1605-1617
    • Hidalgo, M.1
  • 36
    • 68949131070 scopus 로고    scopus 로고
    • Stat3 in CD4+ T helper cell differentiation and inflammatory diseases
    • Egwuagu CE. Stat3 in CD4+ T helper cell differentiation and inflammatory diseases. Cytokine. 2009;47:149-156.
    • (2009) Cytokine , vol.47 , pp. 149-156
    • Egwuagu, C.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.