Postresuscitation administration of doxycycline preserves cardiac contractile function in hypoxia-reoxygenation injury of newborn piglets

Critical Care Medicine

Volumn 42, Issue 4, 2014, Pages

  Labossiere, Joseph R ^a   Pelletier, Jean Sebastian ^a   Ali, Mohammad A ^a   Thiesen, Aducio ^a   Schulz, Richard ^a   Bigam, David L ^a   Cheung, Po Yin ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

asphyxia neonatorum; doxycycline; intensive care; matrix metalloproteinase inhibitors; matrix metalloproteinase 2; swine

Indexed keywords

DOXYCYCLINE; GELATIN; GELATINASE A; LACTIC ACID; LIPID HYDROPEROXIDE; TROPONIN I;

ACIDOSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; CARDIOGENIC SHOCK; CHRONOTROPISM; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GELATIN ZYMOGRAPHY; HEART FUNCTION; HEART INJURY; HEART MUSCLE CONTRACTILITY; HEART MUSCLE INJURY; HEART MUSCLE ISCHEMIA; HEART OUTPUT; HYPOTENSION; IMMUNOPRECIPITATION; LUNG ARTERY PRESSURE; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PIGLET; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; REOXYGENATION; RESUSCITATION; SHAM PROCEDURE; WESTERN BLOTTING; ZYMOGRAPHY;

ACIDOSIS; ANIMALS; ANIMALS, NEWBORN; CARDIAC OUTPUT; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXYCYCLINE; HEMODYNAMICS; HYPOTENSION; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE INHIBITORS; MYOCARDIAL REPERFUSION INJURY; OXIDATIVE STRESS; RANDOM ALLOCATION; RESUSCITATION; SHOCK, CARDIOGENIC; SWINE; TROPONIN I;

EID: 84896670112     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0000000000000135     Document Type: Article

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