Cardiac dysfunction in an animal model of neonatal asphyxia is associated with increased degradation of MLC1 by MMP-2

Basic Research in Cardiology

Volumn 104, Issue 6, 2009, Pages 669-679

  Doroszko, Adrian ^a   Polewicz, Dorota ^a   Sawicka, Jolanta ^a   Richardson, J Steven ^a   Sawicki, Grzegorz ^a,c   Cheung, Po Yin ^b  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

^c WROCLAW MEDICAL UNIVERSITY   (Poland)

Author keywords

Heart injury; Hypoxia reoxygenation; MLC1; MMP 2; Newborns; Peroxynitrite

Indexed keywords

GELATINASE A; MYOSIN LIGHT CHAIN; PEROXYNITRITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; CHEMICAL ANALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; HEART DISEASE; HEART FUNCTION; HEART OUTPUT; HEART STROKE VOLUME; MASS SPECTROMETRY; MEAN ARTERIAL PRESSURE; NEWBORN; NEWBORN HYPOXIA; NITRATION; NITROSYLATION; NONHUMAN; OXIDATIVE STRESS; PIGLET; PROGNOSIS; PROTEIN DEGRADATION; PROTEIN STRUCTURE; REOXYGENATION;

ANIMALS; ANIMALS, NEWBORN; ANOXIA; ASPHYXIA NEONATORUM; BLOTTING, WESTERN; DISEASE MODELS, ANIMAL; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; HEART DISEASES; HEART FUNCTION TESTS; HEMODYNAMICS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOPRECIPITATION; INFANT, NEWBORN; MATRIX METALLOPROTEINASE 2; MYOSIN LIGHT CHAINS; SWINE;

EID: 70349652283     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-009-0035-1     Document Type: Article

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