Cardiovascular dysfunction in infants with neonatal encephalopathy

Archives of Disease in Childhood

Volumn 97, Issue 4, 2012, Pages 372-375

  Armstrong, Katey ^a,b,c   Franklin, Orla ^b   Sweetman, Deirdre ^a,c   Molloy, Eleanor J ^a,c,d,e  

^a NATIONAL MATERNITY HOSPITAL   (Ireland)

^b OUR LADY S CHILDREN S HOSPITAL   (Ireland)

^c NATIONAL CHILDREN S RESEARCH CENTRE   (Ireland)

^d ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^e UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; BRAIN NATRIURETIC PEPTIDE; CREATINE KINASE BB; CREATINE KINASE MB; CREATINE KINASE MM; DOBUTAMINE; DOPAMINE; MILRINONE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PLACEBO; TROPONIN C; TROPONIN I; TROPONIN T;

APOPTOSIS; BONE MARROW TRANSPLANTATION; BRAIN DISEASE; CARDIOVASCULAR SYSTEM EXAMINATION; CELL DEATH; CELL LINEAGE; CELL TRANSPLANTATION; CREATINE KINASE BLOOD LEVEL; CYTOSOL; DISEASE SEVERITY; ECHOCARDIOGRAPHY; FETUS HEART RATE; FOLLOW UP; HEART ARRHYTHMIA; HEART DISEASE; HEART EJECTION FRACTION; HEART FUNCTION; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE CONTRACTILITY; HEART MUSCLE INJURY; HEART MUSCLE ISCHEMIA; HEART OUTPUT; HEART RATE VARIABILITY; HEART STROKE VOLUME; HEART VENTRICLE ARRHYTHMIA; HUMAN; HYPERTENSION; HYPOTHERMIA; LOW DRUG DOSE; LUNG BLOOD VESSEL; M MODE ECHOCARDIOGRAPHY; NEWBORN DISEASE; NEWBORN HYPOXIA; NEWBORN MORTALITY; PERSISTENT PULMONARY HYPERTENSION; PRIORITY JOURNAL; PROGNOSIS; PULMONARY HYPERTENSION; Q WAVE; REVIEW; SIDE EFFECT; ST SEGMENT; STEM CELL; STEM CELL RESEARCH; SYSTEMIC VASCULAR RESISTANCE; T WAVE; TACHYCARDIA; TISSUE DOPPLER IMAGING; TISSUE NECROSIS; UMBILICAL CORD BLOOD; VASOCONSTRICTION;

ASPHYXIA NEONATORUM; BIOLOGICAL MARKERS; CARDIOVASCULAR DISEASES; HUMANS; HYPOTHERMIA, INDUCED; HYPOXIA-ISCHEMIA, BRAIN; INFANT, NEWBORN;

EID: 84859158635     PISSN: 00039888     EISSN: 14682044     Source Type: Journal    
DOI: 10.1136/adc.2011.214205     Document Type: Review

References (66)

1. Azzopardi D, Brocklehurst P, Edwards D, et al. The TOBY Study. Whole body hypothermia for the treatment of perinatal asphyxial encephalopathy: a randomised controlled trial. BMC Pediatr 2008;8:17.
2. Martín-Ancel A, García-Alix A, Gayá F, e t al. M ultiple organ involvement in perinatal asphyxia. J Pediatr 1995;127:786-93.
3. Shah P, Riphagen S, Beyene J, et al. M ultiorgan dysfunction in infants with postasphyxial hypoxic-ischaemic encephalopathy. Arch Dis Child Fetal Neonatal Ed 2004;89:F152-5.
4. Evans N. W hich inotrope for which baby? Arch Dis Child Fetal Neonatal Ed 2006;91:F213-20
5. Barberi I, Calabrò MP, Cordaro S, et al. Myocardial ischaemia in neonates with perinatal asphyxia. Electrocardiographic, echocardiographic and enzymatic correlations. Eur J Pediatr 1999;158:742-7. (Pubitemid 29390115)
6. Fatemi A, Wilson MA, Johnston MV. Hypoxic-ischemic encephalopathy in the term infant. Clin Perinatol 2009;36:835-58, vii.
7. Evans N, Kluckow M, Currie A. Range of echocardiographic fi ndings in term neonates with high oxygen requirements. Arch Dis Child Fetal Neonatal Ed 1998;78:F105-11.
8. Calbet JA, Robach P, Lundby C. The exercising heart at altitude. Cell Mol Life Sci 2009;66:3601-13.
9. Abdel-Aleem S, St Louis JD, Hughes GC, et al. Metabolic changes in the normal and hypoxic neonatal myocardium. Ann N Y Acad Sci 1999;874:254-61. (Pubitemid 29351946)
10. Asano G, Takashi E, Ishiwata T, et al. Pathogenesis and protection of ischemia and reperfusion injury in myocardium. J Nippon Med Sch 2003;70:384-92. (Pubitemid 37372854)
11. Dakshinamurti S. Pathophysiologic mechanisms of persistent pulmonary hypertension of the newborn. Pediatr Pulmonol 2005;39:492-503. (Pubitemid 40696319)
12. Davidson D, Barefi eld ES, Kattwinkel J, et al. Inhaled nitric oxide for the early treatment of persistent pulmonary hypertension of the term newborn: a randomized, double-masked, placebo-controlled, dose-response, multicenter study. The I-NO/ PPHN Study Group. Pediatrics 1998;101:325-34.
13. Kodama Y, Sameshima H, Ikeda T, et al. Intrapartum fetal heart rate patterns in infants (> or =34 weeks) with poor neurological outcome. Early Hum Dev 2009; 85:235-8.
14. Leutmezer F, Schernthaner C, Lurger S, et al. Electrocardiographic changes at the onset of epileptic seizures. Epilepsia 2003;44:348-54. (Pubitemid 36343765)
15. Cherian PJ, Blok JH, Swarte RM, et al. Heart rate changes are insensitive for detecting postasphyxial seizures in neonates. Neurology 2006;67:2221-3. (Pubitemid 46035481)
16. Jedeikin R, Primhak A, Shennan AT, et al. Serial electrocardiographic changes in healthy and stressed neonates. Arch Dis Child 1983;58:605-11. (Pubitemid 13035706)
17. Kanik E, Ozer EA, Bakiler AR, et al. Assessment of myocardial dysfunction in neonates with hypoxic-ischemic encephalopathy: is it a significant predictor of mortality? J Matern Fetal Neonatal Med 2009;22:239-42.
18. Kadivar M, Kiani A, Kocharian A, et al. Echocardiography and management of sick neonates in the intensive care unit. Congenit Heart Dis 2008;3:325-9.
19. Lopez L, Colan SD, Frommelt PC, et al. Recommendations for quantification methods during the performance of a pediatric echocardiogram: a report from the Pediatric Measurements Writing Group of the American Society of Echocardiography Pediatric and Congenital Heart Disease Council. J Am Soc Echocardiogr 2010; 23:465- 95; quiz 576-7.
20. Wei Y, Xu J, Xu T, et al. Left ventricular systolic function of newborns with asphyxia evaluated by tissue Doppler imaging. Pediatr Cardiol 2009;30:741-6.
21. Negrine RJ, Chikermane A, Wright JG, et al. Assessment of myocardial function in neonates using tissue Doppler imaging. Arch Dis Child Fetal Neonatal Ed Published Online First: 30 October 2010 doi:10.1136/adc.2009.175109.
22. Mori K, Nakagawa R, Nii M, et al. Pulsed wave Doppler tissue echocardiography assessment of the long axis function of the right and left ventricles during the early neonatal period. Heart 2004;90:175-80. (Pubitemid 38147153)
23. Wei Y, Xu T, Xu JX, et al. [Evaluation of cardiac function after neonatal asphyxia by Doppler tissue imaging]. Zhonghua Yi Xue Za Zhi 2009;89:117-20.
24. Tsutsumi T, Ishii M, Eto G, et al. Serial evaluation for myocardial performance in fetuses and neonates using a new Doppler index. Pediatr Int 1999;41:722-7. (Pubitemid 30004379)
25. Ichihashi K, Yada Y, Takahashi N, et al. Utility of a Doppler-derived index combining systolic and diastolic performance (Tei index) for detecting hypoxic cardiac damage in newborns. J Perinat Med 2005;33:549-52. (Pubitemid 41769717)
26. Matter M, Abdel-Hady H, Attia G, et al. Myocardial performance in asphyxiated fullterm infants assessed by Doppler tissue imaging. Pediatr Cardiol 2010;31:634-42.
27. Greenough A, Khetriwal B. Pulmonary hypertension in the newborn. Paediatr Respir Rev 2005;6:111-16. (Pubitemid 40692048)
28. Thoresen M, Whitelaw A. Cardiovascular changes during mild therapeutic hypothermia and rewarming in infants with hypoxic-ischemic encephalopathy. Pediatrics 2000;106:92-9. (Pubitemid 30436878)
29. Osborn DA. Diagnosis and treatment of preterm transitional circulatory compromise. Early Hum Dev 2005;81:413-22. (Pubitemid 40791131)
30. Spies C, Haude V, Fitzner R, et al. Serum cardiac troponin T as a prognostic marker in early sepsis. Chest 1998;113:1055-63. (Pubitemid 28216454)
31. El-Khuffash A, Davis PG, Walsh K, et al. Cardiac troponin T and N-terminal-pro-B type natriuretic peptide refl ect myocardial function in preterm infants. J Perinatol 2008;28:482-6. (Pubitemid 351973990)
32. Fromm RE, Jr. Cardiac troponins in the intensive care unit: common causes of increased levels and interpretation. Crit Care Med 2007;35:584-8.
33. Trevisanuto D, Doglioni N, Altinier S, et al. Cardiac troponin I at birth is of fetalneonatal origin. Arch Dis Child Fetal Neonatal Ed 2009;94:F464-6.
34. Børke WB, Munkeby BH, Mørkrid L, et al. Resuscitation with 100% O(2) does not protect the myocardium in hypoxic newborn piglets. Arch Dis Child Fetal Neonatal Ed 2004;89:F156-60.
35. Günes T, Oztürk MA, Köklü SM, et al. Troponin-T levels in perinatally asphyxiated infants during the fi rst 15 days of life. Acta Paediatr 2005;94:1638-43.
36. Szymankiewicz M, Matuszczak-Wleklak M, Vidyasagar D, et al. Retrospective diagnosis of hypoxic myocardial injury in premature newborns. J Perinat Med 2006;34:220-5.
37. de Winter RJ, Koster RW, Sturk A, et al. Value of myoglobin, troponin T, and CK-MBmass in ruling out an acute myocardial infarction in the emergency room. Circulation 1995;92:3401-7.
38. Ellis AK. Serum protein measurements and the diagnosis of acute myocardial infarction. Circulation 1991;83:1107-9.
39. El-Khuffash A, Molloy EJ. Are B-type natriuretic peptide (BNP) and N-terminal-pro- BNP useful in neonates? Arch Dis Child Fetal Neonatal Ed 2007; 92:320-4.
40. El-Khuffash AF, Slevin M, McNamara PJ, et al. Troponin T, N-terminal pro natriuretic peptide and a patent ductus arteriosus scoring system predict death before discharge or neurodevelopmental outcome at 2 years in preterm infants. Arch Dis Child Fetal Neonatal Ed 2011;96:F133-7.
41. Koch A, Singer H. Normal values of B type natriuretic peptide in infants, children, and adolescents. Heart 2003;89:875-8. (Pubitemid 36920810)
42. Brierley J, Carcillo JA, Choong K, et al. Clinical practice parameters for hemodynamic support of pediatric and neonatal septic shock: 2007 update from the American College of Critical Care Medicine. Crit Care Med 2009;37:666-88.
43. Biban P, Filipovic-Grcic B, Biarent D, et al. New cardiopulmonary resuscitation guidelines 2010: managing the newly born in delivery room. Early Hum Dev 2011;87:9-11.
44. Kecskes Z, Healy G, Jensen A. Fluid restriction for term infants with hypoxic-ischaemic encephalopathy following perinatal asphyxia. Cochrane Database Syst Rev 2005;3:CD004337.
45. Hunt R, Osborn D. Dopamine for prevention of morbidity and mortality in term newborn infants with suspected perinatal asphyxia. Cochrane Database Syst Rev 2002;3:CD003484.
46. Paradisis M, Osborn DA. Adrenaline for prevention of morbidity and mortality in preterm infants with cardiovascular compromise. Cochrane Database Syst Rev 2004;1:CD003958.
47. Chang AC, Atz AM, Wernovsky G, et al. Milrinone: systemic and pulmonary hemodynamic effects in neonates after cardiac surgery. Crit Care Med 1995;23:1907-14.
48. Joynt C, Bigam DL, Charrois G, et al. Milrinone, dobutamine or epinephrine use in asphyxiated newborn pigs resuscitated with 100% oxygen. Intensive Care Med 2010;36:1058-66.
49. Gebauer CM, Knuepfer M, Robel-Tillig E, et al. Hemodynamics among neonates with hypoxic-ischemic encephalopathy during whole-body hypothermia and passive rewarming. Pediatrics 2006;117:843-50. (Pubitemid 46063228)
50. Battin MR, Thoresen M, Robinson E, et al. Does head cooling with mild systemic hypothermia affect requirement for blood pressure support? Pediatrics 2009;123:1031-6.
51. Jacobs S, Hunt R, Tarnow-Mordi W, et al. Cooling for newborns with hypoxic ischaemic encephalopathy. Cochrane Database Syst Rev 2007;4:CD003311.
52. Singla DK. Embryonic stem cells in cardiac repair and regeneration. Antioxid Redox Signal 2009;11:1857-63.
53. Kaushal S, Jacobs JP, Gossett JG, et al. Innovation in basic science: stem cells and their role in the treatment of paediatric cardiac failure-opportunities and challenges. Cardiol Young 2009;19 (Suppl 2): 74-84.
54. Behfar A, Perez-Terzic C, Faustino RS, et al. Cardiopoietic programming of embryonic stem cells for tumor-free heart repair. J Exp Med 2007;204:405-20. (Pubitemid 46294555)
55. Dimmeler S, Zeiher AM. Cell therapy of acute myocardial infarction: open questions. Cardiology 2009;113:155-60.
56. Fernández-Avilés F, San Román JA, García-Frade J, et al. Experimental and clinical regenerative capability of human bone marrow cells after myocardial infarction. Circ Res 2004;95:742-8. (Pubitemid 39331935)
57. Wollert KC, Meyer GP, Lotz J, et al. Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial. Lancet 2004;364:141-8. (Pubitemid 38891685)
58. Losordo DW, Schatz RA, White CJ, et al. Intramyocardial transplantation of autologous CD34+ stem cells for intractable angina: a phase I/IIa double-blind, randomized controlled trial. Circulation 2007;115:3165-72. (Pubitemid 47018140)
59. Prat-Vidal C, Roura S, Farré J, et al. Umbilical cord blood-derived stem cells spontaneously express cardiomyogenic traits. Transplant Proc 2007;39:2434-7. (Pubitemid 47418128)
60. Davies B, Elwood NJ, Li S, et al. Human cord blood stem cells enhance neonatal right ventricular function in an ovine model of right ventricular training. Ann Thorac Surg 2010;89:585-93, 593.e1-4.
61. Subhedar NV, Shaw NJ. Dopamine versus dobutamine for hypotensive preterm infants. Cochrane Database Syst Rev 2003;3:CD001242.
62. Ohlsson A, Walia R, Shah SS. Ibuprofen for the treatment of patent ductus arteriosus in preterm and/or low birth weight infants. Cochrane Database Syst Rev 2010;4:CD003481.
63. Hirsch R, Landt Y, Porter S, et al. Cardiac troponin I in pediatrics: normal values and potential use in the assessment of cardiac injury. J Pediatr 1997;130:872-7. (Pubitemid 27495113)
64. Guller B, Fields AI, Coleman MG, et al. Changes in cardiac rhythm in children treated with dopamine. Crit Care Med 1978;6:151-4.
65. Seri I. Hydrocortisone and vasopressor-resistant shock in preterm neonates. Pediatrics 2006;117:516-18. (Pubitemid 46071614)
66. Tavares M, Rezlan E, Vostroknoutova I, et al. New pharmacologic therapies for acute heart failure. Crit Care Med 2008;36:S112-20.