The function of ORAOV1/LTO1, a gene that is overexpressed frequently in cancer: Essential roles in the function and biogenesis of the ribosome

Oncogene

Volumn 33, Issue 4, 2014, Pages 484-494

  Zhai, C ^a,d   Li, Y ^a   Mascarenhas, C ^b   Lin, Q ^a   Li, K ^a,c   Vyrides, I ^a,e   Grant, C M ^b   Panaretou, B ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c INSTITUTE OF HYDROBIOLOGY   (China)

^d HUBEI UNIVERSITY   (China)

^e CYPRUS UNIVERSITY OF TECHNOLOGY   (Cyprus)

Author keywords

Fe S cluster; Ribosome biogenesis; Squamous cell carcinoma; Translation

Indexed keywords

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATASE; HYDROPEROXIDE; OXIDIZING AGENT; OXYGEN; REACTIVE OXYGEN METABOLITE; ORAOV1 PROTEIN, HUMAN; SACCHAROMYCES CEREVISIAE PROTEIN; TUMOR PROTEIN;

AEROBIC METABOLISM; ARTICLE; BIOGENESIS; CONTROLLED STUDY; ESSENTIAL GENE; GENE FUNCTION; GENE INTERACTION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; LARGE RIBOSOMAL SUBUNIT; MATURATION; MOUTH CANCER; ORAL CANCER OVEREXPRESSED; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; RIBOSOME; RIBOSOME SUBUNIT; TUMOR GENE; YEAST; YEAST CELL; GENETICS; METABOLISM; MOLECULAR GENETICS; NEOPLASM; OPEN READING FRAME; PHYSIOLOGY; PROTEIN SYNTHESIS; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS;

HUMANS; IMMUNOPRECIPITATION; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NEOPLASM PROTEINS; NEOPLASMS; OPEN READING FRAMES; PROTEIN BIOSYNTHESIS; REACTIVE OXYGEN SPECIES; RIBOSOMES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84896616484     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2012.604     Document Type: Article

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