Simultaneous quantification of the glucagon-like peptide-1 (GLP-1) and cholecystokinin (CCK) receptor agonists in rodent plasma by on-line solid phase extraction and LC-MS/MS

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 957, Issue , 2014, Pages 24-29

  Wang, Yan ^a,b   Roth, Jonathan D ^a,c   Taylor, Steven W ^a,d  

^a BRISTOL MYERS SQUIBB   (United States)

^b REGULUS THERAPEUTICS   (United States)

^c ZensunUSA Inc   (United States)

^d QUEST DIAGNOSTICS NICHOLS INSTITUTE   (United States)

Author keywords

Cholecystokinin 1 receptor; Glucagon like peptide 1 receptor; LC MS MS; Pharmacodynamics; Pharmacokinetics; Solid phase extraction

Indexed keywords

DRUG PRODUCTS; LIQUID CHROMATOGRAPHY; MAMMALS; MASS SPECTROMETRY; PHARMACODYNAMICS; PHARMACOKINETICS; PHASE SEPARATION; PLASMAS;

CHOLECYSTOKININ-1 RECEPTORS; GLUCAGON-LIKE PEPTIDE-1; LC-MS/MS; LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY (LC MS/MS); ON-LINE SOLID PHASE EXTRACTION; SELECTED REACTION MONITORING; SIMULTANEOUS DETERMINATIONS; SOLID-PHASE EXTRACTION;

PEPTIDES;

AC 170222; AC 3174; CHOLECYSTOKININ RECEPTOR; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; HORMONE RECEPTOR STIMULATING AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANION EXCHANGE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG EXPOSURE; DRUG ISOLATION; DRUG MONITORING; DRUG STRUCTURE; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; MALE; MOUSE; NONHUMAN; OBESITY; OSMOTIC MINIPUMP; PRIORITY JOURNAL; RAT; SIGNAL NOISE RATIO; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

CHOLECYSTOKININ-1 RECEPTOR; GLUCAGON-LIKE PEPTIDE-1 RECEPTOR; LC-MS/MS; PHARMACODYNAMICS; PHARMACOKINETICS; SOLID PHASE EXTRACTION;

ANIMALS; APPETITE DEPRESSANTS; CHROMATOGRAPHY, LIQUID; LIMIT OF DETECTION; MALE; PEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CHOLECYSTOKININ; RECEPTORS, GLUCAGON; REPRODUCIBILITY OF RESULTS; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

EID: 84896526643     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2014.02.040     Document Type: Article

References (27)

1. Hayes M.R., Kanoski S.E., Alhadeff A.L., Grill H.J. Obesity (Silver Spring) 2011, 19:1342-1349.
2. Mack C., Wilson J., Athanacio J., Reynolds J., Laugero K., Guss S., Vu C., Roth J., Parkes D. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007, 293:R1855-R1863.
3. Geary N., Kissileff H.R., Pi-Sunyer F.X., Hinton V. Am. J. Physiol. 1992, 262:R975-R980.
4. MacIntosh C.G., Morley J.E., Wishart J., Morris H., Jansen J.B., Horowitz M., Chapman I.M. J. Clin. Endocrinol. Metab. 2001, 86:5830-5837.
5. Jordan J., Greenway F.L., Leiter L.A., Li Z., Jacobson P., Murphy K., Hill J., Kler L., Aftring R.P. Clin. Pharmacol. Ther. 2008, 83:281-287.
6. Trevaskis J.L., Lei C., Koda J.E., Weyer C., Parkes D.G., Roth J.D. Obesity (Silver Spring) 2010, 18:21-26.
7. Trevaskis J.L., Turek V.F., Griffin P.S., Wittmer C., Parkes D.G., Roth J.D. Physiol. Behav. 2010, 100:187-195.
8. Irwin N., Hunter K., Montgomery I.A., Flatt P.R. Diabetes Obes. Metab. 2013.
9. Beglinger S., Drewe J., Schirra J., Goke B., D'Amato M., Beglinger C. J. Clin. Endocrinol. Metab. 2010, 95:879-886.
10. Hargrove D.M., Kendall E.S., Reynolds J.M., Lwin A.N., Herich J.P., Smith P.A., Gedulin B.R., Flanagan S.D., Jodka C.M., Hoyt J.A., McCowen K.M., Parkes D.G., Anderson C.M. Regul. Pept. 2007, 141:113-119.
11. Pierson M.E., Comstock J.M., Simmons R.D., Julien R., Kaiser F., Rosamond J.D. J. Med. Chem. 2000, 43:2350-2355.
12. Becher F., Pruvost A., Clement G., Tabet J.C., Ezan E. Anal. Chem. 2006, 78:2306-2313.
13. Ji Q.C., Rodila R., Gage E.M., El-Shourbagy T.A. Anal. Chem. 2003, 75:7008-7014.
14. van den Broek I., Sparidans R.W., Schellens J.H., Beijnen J.H. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2008, 872:1-22.
15. Tamvakopoulos C. Mass Spectrom. Rev. 2007, 26:389-402.
16. Cuyckens F., Dillen L., Cools W., Bockx M., Vereyken L., de Vries R., Mortishire-Smith R.J. Bioanalysis 2012, 4:595-604.
17. Olah E., Bacsoi G., Fekete J., Sharma V.K. J. Chromatogr. Sci. 2012, 50:253-258.
18. Olah T.V. Ernst Schering Res. Found. Workshop 2002, 155-183.
19. van den Broek I., Sparidans R.W., Schellens J.H., Beijnen J.H. Rapid Commun. Mass Spectrom. 2008, 22:2915-2928.
20. Kehler J.R., Bowen C.L., Boram S.L., Evans C.A. Bioanalysis 2010, 2:1461-1468.
21. Zhang H., Xin B., Caporuscio C., Olah T.V. Rapid Commun. Mass Spectrom. 2011, 25:3427-3435.
22. Wang S.J., Wu S.T., Gokemeijer J., Fura A., Krishna M., Morin P., Chen G., Price K., Wang-Iverson D., Olah T., Weiner R., Tymiak A., Jemal M. Anal. Bioanal. Chem. 2012, 402:1229-1239.
23. Furlong M.T., Ouyang Z., Wu S., Tamura J., Olah T., Tymiak A., Jemal M. Biomed. Chromatogr. 2012, 26:1024-1032.
24. Dillen L., Cools W., Vereyken L., Lorreyne W., Huybrechts T., de Vries R., Ghobarah H., Cuyckens F. Bioanalysis 2012, 4:565-579.
25. Wang Y., Qu Y., Bellows C.L., Ahn J.S., Burkey J.L., Taylor S.W. Bioanalysis 2012, 4:2141-2152.
26. Wang Y., Heilig J.S. J. Pharm. Biomed. Anal. 2012, 70:440-446.
27. Sleczka B.G., D'Arienzo C.J., Tymiak A.A., Olah T.V. Bioanalysis 2012, 4:29-40.