메뉴 건너뛰기




Volumn 9, Issue 2, 2014, Pages

Neuroprotective copper bis(thiosemicarbazonato) complexes promote neurite elongation

Author keywords

[No Author keywords available]

Indexed keywords

COPPER COMPLEX; DIACETYLBIS(N4 METHYLTHIOSEMICARBAZONATO)COPPER; GLYOXALBIS(N4 METHYLTHIOSEMICARBAZONATO)COPPER; PHOSPHATASE; TACROLIMUS; UNCLASSIFIED DRUG;

EID: 84896526305     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0090070     Document Type: Article
Times cited : (43)

References (57)
  • 1
    • 43049150678 scopus 로고    scopus 로고
    • Metals in Alzheimer's and Parkinson's diseases
    • Barnham KJ, Bush AI (2008) Metals in Alzheimer's and Parkinson's diseases. Curr Opin Chem Biol 12: 222-228.
    • (2008) Curr Opin Chem Biol , vol.12 , pp. 222-228
    • Barnham, K.J.1    Bush, A.I.2
  • 2
    • 79959395494 scopus 로고    scopus 로고
    • Iron, zinc and copper in the Alzheimer's disease brain: A quantitative meta-analysis. Some insight on the influence of citation bias on scientific opinion
    • Schrag M, Mueller C, Oyoyo U, Smith MA, Kirsch WM (2011) Iron, zinc and copper in the Alzheimer's disease brain: a quantitative meta-analysis. Some insight on the influence of citation bias on scientific opinion. Prog Neurobiol 94: 296-306.
    • (2011) Prog Neurobiol , vol.94 , pp. 296-306
    • Schrag, M.1    Mueller, C.2    Oyoyo, U.3    Smith, M.A.4    Kirsch, W.M.5
  • 3
    • 79960155322 scopus 로고    scopus 로고
    • Dynamic action of neurometals at the synapse
    • Tamano H, Takeda A (2011) Dynamic action of neurometals at the synapse. Metallomics 3: 656-661.
    • (2011) Metallomics , vol.3 , pp. 656-661
    • Tamano, H.1    Takeda, A.2
  • 4
    • 84896516742 scopus 로고    scopus 로고
    • Copper signaling in the mammalian nervous system: Synaptic effects
    • Gaier ED, Eipper BA, Mains RE (2012) Copper signaling in the mammalian nervous system: Synaptic effects. J Neurosci Res.
    • (2012) J Neurosci Res
    • Gaier, E.D.1    Eipper, B.A.2    Mains, R.E.3
  • 5
    • 20044367504 scopus 로고    scopus 로고
    • Zur bedeutung von kupfer für die pathophysiologie der Alzheimer-krankheit
    • DOI 10.1007/s00115-004-1849-6
    • Kessler H, Pajonk FG, Supprian T, Falkai P, Multhaup G, et al. (2005) [The role of copper in the pathophysiology of Alzheimer's disease]. Nervenarzt 76: 581-585. (Pubitemid 40768538)
    • (2005) Nervenarzt , vol.76 , Issue.5 , pp. 581-585
    • Kessler, H.1    Pajonk, F.-G.2    Supprian, T.3    Falkai, P.4    Multhaup, G.5    Bayer, T.A.6
  • 6
    • 77954344206 scopus 로고    scopus 로고
    • PBT2 rapidly improves cognition in Alzheimer's Disease: Additional phase II analyses
    • Faux NG, Ritchie CW, Gunn A, Rembach A, Tsatsanis A, et al. (2010) PBT2 rapidly improves cognition in Alzheimer's Disease: additional phase II analyses. J Alzheimers Dis 20: 509-516.
    • (2010) J Alzheimers Dis , vol.20 , pp. 509-516
    • Faux, N.G.1    Ritchie, C.W.2    Gunn, A.3    Rembach, A.4    Tsatsanis, A.5
  • 7
    • 48949098573 scopus 로고    scopus 로고
    • Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: A phase IIa, double-blind, randomised, placebocontrolled trial
    • Lannfelt L, Blennow K, Zetterberg H, Batsman S, Ames D, et al. (2008) Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebocontrolled trial. Lancet Neurol 7: 779-786.
    • (2008) Lancet Neurol , vol.7 , pp. 779-786
    • Lannfelt, L.1    Blennow, K.2    Zetterberg, H.3    Batsman, S.4    Ames, D.5
  • 9
    • 80052684579 scopus 로고    scopus 로고
    • The Alzheimer's therapeutic PBT2 promotes amyloid-beta degradation and GSK3 phosphorylation via a metal chaperone activity
    • Crouch PJ, Savva MS, Hung LW, Donnelly PS, Mot AI, et al. (2011) The Alzheimer's therapeutic PBT2 promotes amyloid-beta degradation and GSK3 phosphorylation via a metal chaperone activity. J Neurochem 119: 220-230.
    • (2011) J Neurochem , vol.119 , pp. 220-230
    • Crouch, P.J.1    Savva, M.S.2    Hung, L.W.3    Donnelly, P.S.4    Mot, A.I.5
  • 12
    • 58849090893 scopus 로고    scopus 로고
    • Increasing Cu bioavailability inhibits Abeta oligomers and tau phosphorylation
    • Crouch PJ, Hung LW, Adlard PA, Cortes M, Lal V, et al. (2009) Increasing Cu bioavailability inhibits Abeta oligomers and tau phosphorylation. Proc Natl Acad Sci U S A 106: 381-386.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 381-386
    • Crouch, P.J.1    Hung, L.W.2    Adlard, P.A.3    Cortes, M.4    Lal, V.5
  • 14
    • 84861728900 scopus 로고    scopus 로고
    • The hypoxia imaging agent CuII(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease
    • Hung LW, Villemagne VL, Cheng L, Sherratt NA, Ayton S, et al. (2012) The hypoxia imaging agent CuII(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease. J Exp Med 209: 837-854.
    • (2012) J Exp Med , vol.209 , pp. 837-854
    • Hung, L.W.1    Villemagne, V.L.2    Cheng, L.3    Sherratt, N.A.4    Ayton, S.5
  • 15
    • 83755181392 scopus 로고    scopus 로고
    • Diacetylbis(N(4)-methylthiosemicarbazonato) copper(II) (CuII(atsm)) protects against peroxynitrite-induced nitrosative damage and prolongs survival in amyotrophic lateral sclerosis mouse model
    • Soon CP, Donnelly PS, Turner BJ, Hung LW, Crouch PJ, et al. (2011) Diacetylbis(N(4)-methylthiosemicarbazonato) copper(II) (CuII(atsm)) protects against peroxynitrite-induced nitrosative damage and prolongs survival in amyotrophic lateral sclerosis mouse model. J Biol Chem 286: 44035-44044.
    • (2011) J Biol Chem , vol.286 , pp. 44035-44044
    • Soon, C.P.1    Donnelly, P.S.2    Turner, B.J.3    Hung, L.W.4    Crouch, P.J.5
  • 16
    • 84864551164 scopus 로고    scopus 로고
    • Inhibition of TDP-43 accumulation by bis(thiosemicarbazonato)-copper complexes
    • Parker SJ, Meyerowitz J, James JL, Liddell JR, Nonaka T, et al. (2012) Inhibition of TDP-43 accumulation by bis(thiosemicarbazonato)-copper complexes. PLoS One 7: e42277.
    • (2012) PLoS One , vol.7
    • Parker, S.J.1    Meyerowitz, J.2    James, J.L.3    Liddell, J.R.4    Nonaka, T.5
  • 17
    • 79952610782 scopus 로고    scopus 로고
    • Metal ionophore treatment restores dendritic spine density and synaptic protein levels in a mouse model of Alzheimer's disease
    • Adlard PA, Bica L, White AR, Nurjono M, Filiz G, et al. (2011) Metal ionophore treatment restores dendritic spine density and synaptic protein levels in a mouse model of Alzheimer's disease. PLoS One 6: e17669.
    • (2011) PLoS One , vol.6
    • Adlard, P.A.1    Bica, L.2    White, A.R.3    Nurjono, M.4    Filiz, G.5
  • 18
    • 41949115990 scopus 로고    scopus 로고
    • Selective intracellular release of copper and zinc ions from bis(thiosemicarbazonato) complexes reduces levels of Alzheimer disease amyloid-beta peptide
    • Donnelly PS, Caragounis A, Du T, Laughton KM, Volitakis I, et al. (2008) Selective intracellular release of copper and zinc ions from bis(thiosemicarbazonato) complexes reduces levels of Alzheimer disease amyloid-beta peptide. J Biol Chem 283: 4568-4577.
    • (2008) J Biol Chem , vol.283 , pp. 4568-4577
    • Donnelly, P.S.1    Caragounis, A.2    Du, T.3    Laughton, K.M.4    Volitakis, I.5
  • 19
    • 84856009969 scopus 로고    scopus 로고
    • An impaired mitochondrial electron transport chain increases retention of the hypoxia imaging agent diacetylbis(4-methylthiosemicarbazonato)copperII
    • Donnelly PS, Liddell JR, Lim S, Paterson BM, Cater MA, et al. (2012) An impaired mitochondrial electron transport chain increases retention of the hypoxia imaging agent diacetylbis(4-methylthiosemicarbazonato)copperII. Proc Natl Acad Sci U S A 109: 47-52.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 47-52
    • Donnelly, P.S.1    Liddell, J.R.2    Lim, S.3    Paterson, B.M.4    Cater, M.A.5
  • 20
    • 2342537758 scopus 로고    scopus 로고
    • Copper(II) and nickel(II) complexes of glyoxaldehyde bis{N(3)-substituted thiosemicarbazones}
    • Beraldo H, Boyd L, West D (1997) Copper(II) and nickel(II) complexes of glyoxaldehyde bis{N(3)-substituted thiosemicarbazones}. Transition Metal Chemistry 23: 67-71.
    • (1997) Transition Metal Chemistry , vol.23 , pp. 67-71
    • Beraldo, H.1    Boyd, L.2    West, D.3
  • 22
    • 0001032885 scopus 로고
    • The preparation of some thiosemicarbazones and their copper complexes: Part iii
    • Gingras BA, Suprunchuk T, Bayley CH (1962) The preparation of some thiosemicarbazones and their copper complexes: part iii. Canadian Journal of Chemistry 40: 1053-1059.
    • (1962) Canadian Journal of Chemistry , vol.40 , pp. 1053-1059
    • Gingras, B.A.1    Suprunchuk, T.2    Bayley, C.H.3
  • 24
    • 80053340219 scopus 로고    scopus 로고
    • Mechanisms controlling the cellular accumulation of copper bis(thiosemicarbazonato) complexes
    • Price KA, Crouch PJ, Volitakis I, Paterson BM, Lim S, et al. (2011) Mechanisms controlling the cellular accumulation of copper bis(thiosemicarbazonato) complexes. Inorg Chem 50: 9594-9605.
    • (2011) Inorg Chem , vol.50 , pp. 9594-9605
    • Price, K.A.1    Crouch, P.J.2    Volitakis, I.3    Paterson, B.M.4    Lim, S.5
  • 25
    • 82455186198 scopus 로고    scopus 로고
    • Subcellular localization of a fluorescent derivative of CuII(atsm) offers insight into the neuroprotective action of CuII(atsm)
    • Price KA, Crouch PJ, Lim S, Paterson BM, Liddell JR, et al. (2011) Subcellular localization of a fluorescent derivative of CuII(atsm) offers insight into the neuroprotective action of CuII(atsm). Metallomics 3: 1280-1290.
    • (2011) Metallomics , vol.3 , pp. 1280-1290
    • Price, K.A.1    Crouch, P.J.2    Lim, S.3    Paterson, B.M.4    Liddell, J.R.5
  • 26
    • 79551681223 scopus 로고    scopus 로고
    • Internal radiotherapy with copper-64-diacetyl-bis (N4- methylthiosemicarbazone) reduces CD133+ highly tumorigenic cells and metastatic ability of mouse colon carcinoma
    • Yoshii Y, Furukawa T, Kiyono Y, Watanabe R, Mori T, et al. (2011) Internal radiotherapy with copper-64-diacetyl-bis (N4-methylthiosemicarbazone) reduces CD133+ highly tumorigenic cells and metastatic ability of mouse colon carcinoma. Nucl Med Biol 38: 151-157.
    • (2011) Nucl Med Biol , vol.38 , pp. 151-157
    • Yoshii, Y.1    Furukawa, T.2    Kiyono, Y.3    Watanabe, R.4    Mori, T.5
  • 27
    • 84864449619 scopus 로고    scopus 로고
    • The challenges of using a copper fluorescent sensor (CS1) to track intracellular distributions of copper in neuronal and glial cells
    • Price KA (2012) The challenges of using a copper fluorescent sensor (CS1) to track intracellular distributions of copper in neuronal and glial cells. Chemical Science 3: 2748-2759.
    • (2012) Chemical Science , vol.3 , pp. 2748-2759
    • Price, K.A.1
  • 28
    • 0028228616 scopus 로고
    • Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
    • DOI 10.1016/0092-8674(94)90133-3
    • Cowley S, Paterson H, Kemp P, Marshall CJ (1994) Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell 77: 841-852. (Pubitemid 24187682)
    • (1994) Cell , vol.77 , Issue.6 , pp. 841-852
    • Cowley, S.1    Paterson, H.2    Kemp, P.3    Marshall, C.J.4
  • 29
    • 0029034774 scopus 로고
    • Inhibition of MAP kinase kinase blocks the differentiation of PC-12 cells induced by nerve growth factor
    • Pang L, Sawada T, Decker SJ, Saltiel AR (1995) Inhibition of MAP kinase kinase blocks the differentiation of PC-12 cells induced by nerve growth factor. J Biol Chem 270: 13585-13588.
    • (1995) J Biol Chem , vol.270 , pp. 13585-13588
    • Pang, L.1    Sawada, T.2    Decker, S.J.3    Saltiel, A.R.4
  • 30
    • 0032544550 scopus 로고    scopus 로고
    • Requirement of p38 mitogen-activated protein kinase for neuronal differentiation in PC12 cells
    • DOI 10.1074/jbc.273.38.24285
    • Morooka T, Nishida E (1998) Requirement of p38 mitogen-activated protein kinase for neuronal differentiation in PC12 cells. J Biol Chem 273: 24285-24288. (Pubitemid 28454911)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.38 , pp. 24285-24288
    • Morooka, T.1    Nishida, E.2
  • 31
    • 79951725943 scopus 로고    scopus 로고
    • Cell cycle arrest in cultured neuroblastoma cells exposed to a bis(thiosemicarbazonato) metal complex
    • Bica L, Meyerowitz J, Parker SJ, Caragounis A, Du T, et al. (2011) Cell cycle arrest in cultured neuroblastoma cells exposed to a bis(thiosemicarbazonato) metal complex. Biometals 24: 117-133.
    • (2011) Biometals , vol.24 , pp. 117-133
    • Bica, L.1    Meyerowitz, J.2    Parker, S.J.3    Caragounis, A.4    Du, T.5
  • 32
    • 79961117695 scopus 로고    scopus 로고
    • C-Jun Nterminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stress
    • Meyerowitz J, Parker SJ, Vella LJ, Ng D, Price KA, et al. (2011) C-Jun Nterminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stress. Mol Neurodegener 6: 57.
    • (2011) Mol Neurodegener , vol.6 , pp. 57
    • Meyerowitz, J.1    Parker, S.J.2    Vella, L.J.3    Ng, D.4    Price, K.A.5
  • 33
    • 0141726829 scopus 로고    scopus 로고
    • The concerted signaling of ERK1/2 and JNKs is essential for PC12 cell neuritogenesis and converges at the level of target proteins
    • DOI 10.1016/S1044-7431(03)00126-X
    • Waetzig V, Herdegen T (2003) The concerted signaling of ERK1/2 and JNKs is essential for PC12 cell neuritogenesis and converges at the level of target proteins. Mol Cell Neurosci 24: 238-249. (Pubitemid 37194548)
    • (2003) Molecular and Cellular Neuroscience , vol.24 , Issue.1 , pp. 238-249
    • Waetzig, V.1    Herdegen, T.2
  • 34
    • 0347004650 scopus 로고    scopus 로고
    • Bcl-2 enhances neurite extension via activation of c-Jun N-terminal kinase
    • DOI 10.1016/j.bbrc.2003.12.094
    • Eom DS, Choi WS, Oh YJ (2004) Bcl-2 enhances neurite extension via activation of c-Jun N-terminal kinase. Biochem Biophys Res Commun 314: 377-381. (Pubitemid 38084727)
    • (2004) Biochemical and Biophysical Research Communications , vol.314 , Issue.2 , pp. 377-381
    • Eom, D.-S.1    Choi, W.-S.2    Oh, Y.J.3
  • 36
    • 79151481130 scopus 로고    scopus 로고
    • Calcineurin inhibition with FK506 ameliorates dendritic spine density deficits in plaque-bearing Alzheimer model mice
    • Rozkalne A, Hyman BT, Spires-Jones TL (2011) Calcineurin inhibition with FK506 ameliorates dendritic spine density deficits in plaque-bearing Alzheimer model mice. Neurobiol Dis 41: 650-654.
    • (2011) Neurobiol Dis , vol.41 , pp. 650-654
    • Rozkalne, A.1    Hyman, B.T.2    Spires-Jones, T.L.3
  • 37
    • 0025893168 scopus 로고
    • Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
    • Liu J, Farmer JD Jr, Lane WS, Friedman J, Weissman I, et al. (1991) Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 66: 807-815. (Pubitemid 121001714)
    • (1991) Cell , vol.66 , Issue.4 , pp. 807-815
    • Liu, J.1    Farmer Jr., J.O.2    Lane, W.S.3    Friedman, J.4    Weissman, I.5    Schreiber, S.L.6
  • 38
    • 0026503434 scopus 로고
    • Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A
    • Fruman DA, Klee CB, Bierer BE, Burakoff SJ (1992) Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A. Proc Natl Acad Sci U S A 89: 3686-3690.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 3686-3690
    • Fruman, D.A.1    Klee, C.B.2    Bierer, B.E.3    Burakoff, S.J.4
  • 39
    • 84857264431 scopus 로고    scopus 로고
    • Copper complexes as therapeutic agents
    • Duncan C, White AR (2012) Copper complexes as therapeutic agents. Metallomics 4: 127-138.
    • (2012) Metallomics , vol.4 , pp. 127-138
    • Duncan, C.1    White, A.R.2
  • 41
    • 0141432134 scopus 로고    scopus 로고
    • Differential roles of ERK and JNK in early and late stages of neuritogenesis: A study in a novel PC12 model system
    • DOI 10.1046/j.1471-4159.2003.01961.x
    • Xiao J, Liu Y (2003) Differential roles of ERK and JNK in early and late stages of neuritogenesis: a study in a novel PC12 model system. J Neurochem 86: 1516-1523. (Pubitemid 37174268)
    • (2003) Journal of Neurochemistry , vol.86 , Issue.6 , pp. 1516-1523
    • Xiao, J.1    Liu, Y.2
  • 42
    • 78649420524 scopus 로고    scopus 로고
    • Neurites from PC12 cells are connected to each other by synapse-like structures
    • Jeon CY, Jin JK, Koh YH, Chun W, Choi IG, et al. (2010) Neurites from PC12 cells are connected to each other by synapse-like structures. Synapse 64: 765-772.
    • (2010) Synapse , vol.64 , pp. 765-772
    • Jeon, C.Y.1    Jin, J.K.2    Koh, Y.H.3    Chun, W.4    Choi, I.G.5
  • 43
    • 0345704610 scopus 로고
    • Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
    • Greene LA, Tischler AS (1976) Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci U S A 73: 2424-2428.
    • (1976) Proc Natl Acad Sci U S A , vol.73 , pp. 2424-2428
    • Greene, L.A.1    Tischler, A.S.2
  • 44
    • 33749017645 scopus 로고    scopus 로고
    • Axon pruning: An essential step underlying the developmental plasticity of neuronal connections
    • DOI 10.1098/rstb.2006.1883
    • Low LK, Cheng HJ (2006) Axon pruning: an essential step underlying the developmental plasticity of neuronal connections. Philos Trans R Soc Lond B Biol Sci 361: 1531-1544. (Pubitemid 44450209)
    • (2006) Philosophical Transactions of the Royal Society B: Biological Sciences , vol.361 , Issue.1473 , pp. 1531-1544
    • Low, L.K.1    Cheng, H.-J.2
  • 45
    • 0037180832 scopus 로고    scopus 로고
    • Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex
    • DOI 10.1038/nature01273
    • Trachtenberg JT, Chen BE, Knott GW, Feng G, Sanes JR, et al. (2002) Longterm in vivo imaging of experience-dependent synaptic plasticity in adult cortex. Nature 420: 788-794. (Pubitemid 36019621)
    • (2002) Nature , vol.420 , Issue.6917 , pp. 788-794
    • Trachtenberg, J.T.1    Chen, B.E.2    Knott, G.W.3    Feng, G.4    Sanes, J.R.5    Welker, E.6    Svoboda, K.7
  • 46
    • 0036774951 scopus 로고    scopus 로고
    • Axon pathology in neurological disease: A neglected therapeutic target
    • DOI 10.1016/S0166-2236(02)02255-5, PII S0166223602022555
    • Coleman MP, Perry VH (2002) Axon pathology in neurological disease: a neglected therapeutic target. Trends Neurosci 25: 532-537. (Pubitemid 35246324)
    • (2002) Trends in Neurosciences , vol.25 , Issue.10 , pp. 532-537
    • Coleman, M.P.1    Perry V.Hugh2
  • 47
    • 14844337444 scopus 로고    scopus 로고
    • NGF promotes copper accumulation required for optimum neurite outgrowth and protein methylation
    • DOI 10.1002/neu.20114
    • Birkaya B, Aletta JM (2005) NGF promotes copper accumulation required for optimum neurite outgrowth and protein methylation. J Neurobiol 63: 49-61. (Pubitemid 40344288)
    • (2005) Journal of Neurobiology , vol.63 , Issue.1 , pp. 49-61
    • Birkaya, B.1    Aletta, J.M.2
  • 49
    • 24144458246 scopus 로고    scopus 로고
    • The developmentally regulated expression of Menkes protein ATP7A suggests a role in axon extension and synaptogenesis
    • DOI 10.1159/000086713
    • El Meskini R, Cline LB, Eipper BA, Ronnett GV (2005) The developmentally regulated expression of Menkes protein ATP7A suggests a role in axon extension and synaptogenesis. Dev Neurosci 27: 333-348. (Pubitemid 41243221)
    • (2005) Developmental Neuroscience , vol.27 , Issue.5 , pp. 333-348
    • El Meskini, R.1    Cline, L.B.2    Eipper, B.A.3    Ronnett, G.V.4
  • 50
    • 0035798238 scopus 로고    scopus 로고
    • The molecular biology of memory storage: A dialogue between genes and synapses
    • DOI 10.1126/science.1067020
    • Kandel ER (2001) The molecular biology of memory storage: a dialogue between genes and synapses. Science 294: 1030-1038. (Pubitemid 33041851)
    • (2001) Science , vol.294 , Issue.5544 , pp. 1030-1038
    • Kandel, E.R.1
  • 51
    • 0035166616 scopus 로고    scopus 로고
    • The neuronal MAP kinase cascade: A biochemical signal integration system subserving synaptic plasticity and memory
    • Sweatt JD (2001) The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory. J Neurochem 76: 1-10.
    • (2001) J Neurochem , vol.76 , pp. 1-10
    • Sweatt, J.D.1
  • 52
    • 2942550646 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases in synaptic plasticity and memory
    • DOI 10.1016/j.conb.2004.04.001, PII S0959438804000649
    • Sweatt JD (2004) Mitogen-activated protein kinases in synaptic plasticity and memory. Curr Opin Neurobiol 14: 311-317. (Pubitemid 38759861)
    • (2004) Current Opinion in Neurobiology , vol.14 , Issue.3 , pp. 311-317
    • Sweatt, J.D.1
  • 53
    • 1342289413 scopus 로고    scopus 로고
    • MAPK cascade signalling and synaptic plasticity
    • Thomas GM, Huganir RL (2004) MAPK cascade signalling and synaptic plasticity. Nat Rev Neurosci 5: 173-183. (Pubitemid 38252474)
    • (2004) Nature Reviews Neuroscience , vol.5 , Issue.3 , pp. 173-183
    • Thomas, G.M.1    Huganir, R.L.2
  • 55
    • 77956190591 scopus 로고    scopus 로고
    • A calcineurin/AKAP complex is required for NMDA receptor-dependent long-term depression
    • Jurado S, Biou V, Malenka RC (2010) A calcineurin/AKAP complex is required for NMDA receptor-dependent long-term depression. Nat Neurosci 13: 1053-1055.
    • (2010) Nat Neurosci , vol.13 , pp. 1053-1055
    • Jurado, S.1    Biou, V.2    Malenka, R.C.3
  • 56
    • 33645022501 scopus 로고    scopus 로고
    • A role for the protein phosphatase 2B in altered hippocampal synaptic plasticity in the aged rat
    • Jouvenceau A, Dutar P (2006) A role for the protein phosphatase 2B in altered hippocampal synaptic plasticity in the aged rat. J Physiol Paris 99: 154-161.
    • (2006) J Physiol Paris , vol.99 , pp. 154-161
    • Jouvenceau, A.1    Dutar, P.2
  • 57
    • 0035872463 scopus 로고    scopus 로고
    • Roles of the metallothionein family of proteins in the central nervous system
    • DOI 10.1016/S0361-9230(01)00452-X, PII S036192300100452X
    • Hidalgo J, Aschner M, Zatta P, Vasak M (2001) Roles of the metallothionein family of proteins in the central nervous system. Brain Res Bull 55: 133-145. (Pubitemid 32722153)
    • (2001) Brain Research Bulletin , vol.55 , Issue.2 , pp. 133-145
    • Hidalgo, J.1    Aschner, M.2    Zatta, P.3    Vasak, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.