Tetrahydrocurcumin induces G2/M cell cycle arrest and apoptosis involving p38 MAPK activation in human breast cancer cells

Food and Chemical Toxicology

Volumn 67, Issue , 2014, Pages 193-200

  Kang, Ning ^a,b   Wang, Miao Miao ^b   Wang, Ying Hui ^b   Zhang, Zhe Nan ^b   Cao, Hong Rui ^b   Lv, Yuan Hao ^b   Yang, Yang ^b   Fan, Peng Hui ^b   Qiu, Feng ^a   Gao, Xiu Mei ^a  

^a TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Breast cancer; Curcumin; G2 M cell cycle arrest; P38 MAPK; Tetrahydrocurcumin

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 9; CDC25C PROTEIN; CELL PROTEIN; CURCUMIN; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; CYTOCHROME C; MITOGEN ACTIVATED PROTEIN KINASE P38; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROTEIN BAX; PROTEIN BCL 2; PROTEIN ICAD; PROTEIN P21; TETRAHYDROCURCUMIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER INHIBITION; CELL PROLIFERATION; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG EFFICACY; ENZYME ACTIVATION; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PROTEIN EXPRESSION; UPREGULATION; ANALOGS AND DERIVATIVES; BREAST TUMOR; CELL CYCLE G2 PHASE; CELL DIVISION; DRUG EFFECTS; ENZYMOLOGY; MCF 7 CELL LINE; METABOLISM; PATHOLOGY;

APOPTOSIS; BREAST NEOPLASMS; CELL DIVISION; CURCUMIN; ENZYME ACTIVATION; G2 PHASE; HUMANS; MCF-7 CELLS; P38 MITOGEN-ACTIVATED PROTEIN KINASES;

EID: 84896525950     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2014.02.024     Document Type: Article

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