메뉴 건너뛰기




Volumn 74, Issue 5, 2014, Pages 1371-1378

P14ARF suppresses tumor-induced thrombosis by regulating the tissue factor pathway

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN C JUN; PROTEIN P53; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR SP1;

EID: 84896511397     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-1951     Document Type: Article
Times cited : (13)

References (49)
  • 2
    • 0842325802 scopus 로고    scopus 로고
    • Pseudopalisades in glioblastoma are hypoxic, express extracellular matrix proteases, and are formed by an actively migrating cell population
    • Brat DJ, Castellano-Sanchez AA, Hunter SB, Pecot M, Cohen C, Hammond EH, et al. Pseudopalisades in glioblastoma are hypoxic, express extracellular matrix proteases, and are formed by an actively migrating cell population. Cancer Res 2004;64:920-7.
    • (2004) Cancer Res , vol.64 , pp. 920-927
    • Brat, D.J.1    Castellano-Sanchez, A.A.2    Hunter, S.B.3    Pecot, M.4    Cohen, C.5    Hammond, E.H.6
  • 3
    • 2342588221 scopus 로고    scopus 로고
    • Vaso-occlusive and prothrombotic mechanisms associated with tumor hypoxia, necrosis, and accelerated growth in glioblastoma
    • Brat DJ, Van Meir EG. Vaso-occlusive and prothrombotic mechanisms associated with tumor hypoxia, necrosis, and accelerated growth in glioblastoma. Lab Invest 2004;84:397-405.
    • (2004) Lab Invest , vol.84 , pp. 397-405
    • Brat, D.J.1    Van Meir, E.G.2
  • 4
    • 0026446102 scopus 로고
    • Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo
    • Plate KH, Breier G, Weich HA, Risau W. Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature 1992;359:845-48.
    • (1992) Nature , vol.359 , pp. 845-848
    • Plate, K.H.1    Breier, G.2    Weich, H.A.3    Risau, W.4
  • 5
    • 0028174337 scopus 로고
    • Glioblastoma growth inhibited in vivo by a dominant-negative flk-1 mutant
    • Millauer B, Shawver LK, Plate KH, Risau W, Ullrich A. Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant. Nature 1994;367:576-9.
    • (1994) Nature , vol.367 , pp. 576-579
    • Millauer, B.1    Shawver, L.K.2    Plate, K.H.3    Risau, W.4    Ullrich, A.5
  • 6
    • 0026485002 scopus 로고
    • Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
    • Shweiki D, Itin A, Soffer D, Keshet E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 1992;359:843-5.
    • (1992) Nature , vol.359 , pp. 843-845
    • Shweiki, D.1    Itin, A.2    Soffer, D.3    Keshet, E.4
  • 8
    • 0034088477 scopus 로고    scopus 로고
    • Tissue factor and cancer procoagulant expressed by glioma cells participate in their thrombin-mediated proliferation
    • Ogiichi T, Hirashima Y, Nakamura S, Endo S, Kurimoto M, Takaku A. Tissue factor and cancer procoagulant expressed by glioma cells participate in their thrombin-mediated proliferation. J Neurooncol 2000;46:1-9.
    • (2000) J Neurooncol , vol.46 , pp. 1-9
    • Ogiichi, T.1    Hirashima, Y.2    Nakamura, S.3    Endo, S.4    Kurimoto, M.5    Takaku, A.6
  • 9
    • 0022456082 scopus 로고
    • Activation of human factor vii in the initiation of tissue factor-dependent coagulation
    • Rao LV, Rapaport SI, Bajaj SP. Activation of human factor VII in the initiation of tissue factor-dependent coagulation. Blood 1986;68: 685-91.
    • (1986) Blood , vol.68 , pp. 685-691
    • Rao, L.V.1    Rapaport, S.I.2    Bajaj, S.P.3
  • 10
    • 65549089078 scopus 로고    scopus 로고
    • Epidermal growth factor receptor and pten modulate tissue factor expression in glioblastoma through jund/activator protein-1 transcriptional activity
    • Rong Y, Belozerov VE, Tucker-Burden C, Chen G, Durden DL, Olson JJ, et al. Epidermal growth factor receptor and PTEN modulate tissue factor expression in glioblastoma through JunD/activator protein-1 transcriptional activity. Cancer Res 2009;69:2540-9.
    • (2009) Cancer Res , vol.69 , pp. 2540-2549
    • Rong, Y.1    Belozerov, V.E.2    Tucker-Burden, C.3    Chen, G.4    Durden, D.L.5    Olson, J.J.6
  • 11
    • 77249101567 scopus 로고    scopus 로고
    • Mutant egfr is required for maintenance of glioma growth in vivo, and its ablation leads to escape from receptor dependence
    • Mukasa A, Wykosky J, Ligon KL, Chin L, Cavenee WK, Furnari F. Mutant EGFR is required for maintenance of glioma growth in vivo, and its ablation leads to escape from receptor dependence. Proc Natl Acad Sci U S A 2010;107:2616-21.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 2616-2621
    • Mukasa, A.1    Wykosky, J.2    Ligon, K.L.3    Chin, L.4    Cavenee, W.K.5    Furnari, F.6
  • 12
    • 77956272974 scopus 로고    scopus 로고
    • Oncogenic epidermal growth factor receptor up-regulates multiple elements of the tissue factor signaling pathway in human glioma cells
    • Magnus N, Garnier D, Rak J. Oncogenic epidermal growth factor receptor up-regulates multiple elements of the tissue factor signaling pathway in human glioma cells. Blood 2010;116:815-8.
    • (2010) Blood , vol.116 , pp. 815-818
    • Magnus, N.1    Garnier, D.2    Rak, J.3
  • 13
    • 13944256192 scopus 로고    scopus 로고
    • Pten and hypoxia regulate tissue factor expression and plasma coagulation by glioblastoma
    • Rong Y, Post DE, Pieper RO, Durden DL, Van Meir EG, Brat DJ. PTEN and hypoxia regulate tissue factor expression and plasma coagulation by glioblastoma. Cancer Res 2005;65:1406-13.
    • (2005) Cancer Res , vol.65 , pp. 1406-1413
    • Rong, Y.1    Post, D.E.2    Pieper, R.O.3    Durden, D.L.4    Van Meir, E.G.5    Brat, D.J.6
  • 14
    • 51049106423 scopus 로고    scopus 로고
    • Aberrant nf-kappab activity is critical in focal necrosis formation of human glioblastoma by regulation of the expression of tissue factor
    • Xie TX, Aldape KD, Gong W, Kanzawa T, Suki D, Kondo S, et al. Aberrant NF-kappaB activity is critical in focal necrosis formation of human glioblastoma by regulation of the expression of tissue factor. Int J Oncol 2008;33:5-15.
    • (2008) Int J Oncol , vol.33 , pp. 5-15
    • Xie, T.X.1    Aldape, K.D.2    Gong, W.3    Kanzawa, T.4    Suki, D.5    Kondo, S.6
  • 15
    • 0037394911 scopus 로고    scopus 로고
    • Procoagulant and anticoagulant mechanisms in human placenta
    • Lanir N, Aharon A, Brenner B. Procoagulant and anticoagulant mechanisms in human placenta. Semin Thromb Hemost 2003;29: 175-84.
    • (2003) Semin Thromb Hemost , vol.29 , pp. 175-184
    • Lanir, N.1    Aharon, A.2    Brenner, B.3
  • 16
    • 74749100743 scopus 로고    scopus 로고
    • Tissue factor pathway inhibitor 2 (tfpi2) is frequently silenced by aberrant promoter hypermethylation in gastric cancer
    • Takada H, Wakabayashi N, Dohi O, Yasui K, Sakakura C, Mitsufuji S, et al. Tissue factor pathway inhibitor 2 (TFPI2) is frequently silenced by aberrant promoter hypermethylation in gastric cancer. Cancer Genet Cytogenet 2010;197:16-24.
    • (2010) Cancer Genet Cytogenet , vol.197 , pp. 16-24
    • Takada, H.1    Wakabayashi, N.2    Dohi, O.3    Yasui, K.4    Sakakura, C.5    Mitsufuji, S.6
  • 17
    • 0042168731 scopus 로고    scopus 로고
    • Promoter methylation and silencing of the tissue factor pathway inhibitor-2 (tfpi-2), a gene encoding an inhibitor of matrix metalloproteinases in human gliomacells
    • Konduri SD, Srivenugopal KS, Yanamandra N, Dinh DH, Olivero WC, Gujrati M, et al. Promoter methylation and silencing of the tissue factor pathway inhibitor-2 (TFPI-2), a gene encoding an inhibitor of matrix metalloproteinases in human gliomacells. Oncogene 2003;22:4509-16.
    • (2003) Oncogene , vol.22 , pp. 4509-4516
    • Konduri, S.D.1    Srivenugopal, K.S.2    Yanamandra, N.3    Dinh, D.H.4    Olivero, W.C.5    Gujrati, M.6
  • 18
    • 77950937747 scopus 로고    scopus 로고
    • Epigenetic inactivation of the placentally imprinted tumor suppressor gene tfpi2 in prostate carcinoma
    • Ribarska T, Ingenwerth M, Goering W, Engers R, Schulz WA. Epigenetic inactivation of the placentally imprinted tumor suppressor gene TFPI2 in prostate carcinoma. Cancer Genomics Proteomics 2010;7: 51-60.
    • (2010) Cancer Genomics Proteomics , vol.7 , pp. 51-60
    • Ribarska, T.1    Ingenwerth, M.2    Goering, W.3    Engers, R.4    Schulz, W.A.5
  • 19
    • 0029587551 scopus 로고
    • Alternative reading frames of the ink4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
    • Quelle DE, Zindy F, Ashmun RA, Sherr CJ. Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest. Cell 1995;83:993-1000.
    • (1995) Cell , vol.83 , pp. 993-1000
    • Quelle, D.E.1    Zindy, F.2    Ashmun, R.A.3    Sherr, C.J.4
  • 20
    • 0032549704 scopus 로고    scopus 로고
    • The ink4a tumor suppressor gene product, p19arf, interacts with mdm2 and neutralizes mdm2's inhibition of p53
    • Pomerantz J, Schreiber-Agus N, Liegeois NJ, Silverman A, Alland L, Chin L, et al. The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53. Cell 1998;92:713-23.
    • (1998) Cell , vol.92 , pp. 713-723
    • Pomerantz, J.1    Schreiber-Agus, N.2    Liegeois, N.J.3    Silverman, A.4    Alland, L.5    Chin, L.6
  • 21
    • 0030728468 scopus 로고    scopus 로고
    • Tumor suppression at the mouse ink4a locus mediated by the alternative reading frame product p19arf
    • Kamijo T, Zindy F, Roussel MF, Quelle DE, Downing JR, Ashmun RA, et al. Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF. Cell 1997;91:649-59.
    • (1997) Cell , vol.91 , pp. 649-659
    • Kamijo, T.1    Zindy, F.2    Roussel, M.F.3    Quelle, D.E.4    Downing, J.R.5    Ashmun, R.A.6
  • 22
    • 85047700405 scopus 로고    scopus 로고
    • Human p14(arf)-mediated cell cycle arrest strictly depends on intact p53 signaling pathways
    • Weber HO, Samuel T, Rauch P, Funk JO. Human p14(ARF)-mediated cell cycle arrest strictly depends on intact p53 signaling pathways. Oncogene 2002;21:3207-12.
    • (2002) Oncogene , vol.21 , pp. 3207-3212
    • Weber, H.O.1    Samuel, T.2    Rauch, P.3    Funk, J.O.4
  • 23
    • 19344364856 scopus 로고    scopus 로고
    • Kemp cj. P19arf suppresses growth, progression, and metastasis of hras-driven carcinomas through p53-dependent and -independent pathways
    • Kelly-Spratt KS, Gurley KE, Yasui Y, Kemp CJ. p19Arf suppresses growth, progression, and metastasis of Hras-driven carcinomas through p53-dependent and -independent pathways. PLoS Biol 2004;2:E242.
    • (2004) PLoS Biol , vol.2
    • Kelly-Spratt, K.S.1    Gurley, K.E.2    Yasui, Y.3
  • 24
    • 0033562997 scopus 로고    scopus 로고
    • Loss of the arf tumor suppressor reverses premature replicative arrest but not radiation hypersensitivity arising from disabled atm function
    • Kamijo T, van de Kamp E, Chong MJ, Zindy F, Diehl JA, Sherr CJ, et al. Loss of the ARF tumor suppressor reverses premature replicative arrest but not radiation hypersensitivity arising from disabled atm function. Cancer Res 1999;59:2464-9.
    • (1999) Cancer Res , vol.59 , pp. 2464-2469
    • Kamijo, T.1    Van De Kamp, E.2    Chong, M.J.3    Zindy, F.4    Diehl, J.A.5    Sherr, C.J.6
  • 26
    • 0032573088 scopus 로고    scopus 로고
    • Rosenberg n. P19(arf) induces p53-dependent apoptosis during abelson virus-mediated pre-b cell transformation
    • Radfar A, Unnikrishnan I, Lee HW, DePinho RA, Rosenberg N. p19(Arf) induces p53-dependent apoptosis during abelson virus-mediated pre-B cell transformation. Proc Natl Acad Sci U S A 1998;95:13194-9.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 13194-13199
    • Radfar, A.1    Unnikrishnan, I.2    Lee, H.W.3    DePinho, R.A.4
  • 28
    • 84859733234 scopus 로고    scopus 로고
    • P14arf inhibits human glioblastoma-induced angiogenesis by upregulating the expression of timp3
    • Zerrouqi A, Pyrzynska B, Febbraio M, Brat DJ, Van Meir EG. P14ARF inhibits human glioblastoma-induced angiogenesis by upregulating the expression of TIMP3. J Clin Invest 2012;122:1283-95.
    • (2012) J Clin Invest , vol.122 , pp. 1283-1295
    • Zerrouqi, A.1    Pyrzynska, B.2    Febbraio, M.3    Brat, D.J.4    Van Meir, E.G.5
  • 29
    • 0032977124 scopus 로고    scopus 로고
    • Frequent co-Alterations of tp53, p16/cdkn2a, p14arf, pten tumor suppressor genes in human glioma cell lines
    • Ishii N, Maier D, Merlo A, Tada M, Sawamura Y, Diserens AC, et al. Frequent co-Alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines. Brain Pathol 1999;9: 469-79.
    • (1999) Brain Pathol , vol.9 , pp. 469-479
    • Ishii, N.1    Maier, D.2    Merlo, A.3    Tada, M.4    Sawamura, Y.5    Diserens, A.C.6
  • 30
    • 19944379133 scopus 로고    scopus 로고
    • Vasculostatin, a proteolytic fragment of brain angiogenesis inhibitor 1, is an antiangiogenic and antitumorigenic factor
    • Kaur B, Brat DJ, Devi NS, Van Meir EG. Vasculostatin, a proteolytic fragment of brain angiogenesis inhibitor 1, is an antiangiogenic and antitumorigenic factor. Oncogene 2005;24:3632-42.
    • (2005) Oncogene , vol.24 , pp. 3632-3642
    • Kaur, B.1    Brat, D.J.2    Devi, N.S.3    Van Meir, E.G.4
  • 31
    • 0037142612 scopus 로고    scopus 로고
    • Anoxia induces macrophage inhibitory cytokine-1 (mic-1) in glioblastoma cells independently of p53 and hif-1
    • Albertoni M, Shaw PH, Nozaki M, Godard S, Tenan M,Hamou MF, et al. Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1. Oncogene 2002;21: 4212-9.
    • (2002) Oncogene , vol.21 , pp. 4212-4219
    • Albertoni, M.1    Shaw, P.H.2    Nozaki, M.3    Godard, S.4    Tenan, M.5    Hamou, M.F.6
  • 32
    • 0035392982 scopus 로고    scopus 로고
    • Formation of intracranial tumors by genetically modified human astrocytes defines four pathways critical in the development of human anaplastic astrocytoma
    • Sonoda Y, Ozawa T, Hirose Y, Aldape KD, McMahon M, Berger MS, et al. Formation of intracranial tumors by genetically modified human astrocytes defines four pathways critical in the development of human anaplastic astrocytoma. Cancer Res 2001;61:4956-60.
    • (2001) Cancer Res , vol.61 , pp. 4956-4960
    • Sonoda, Y.1    Ozawa, T.2    Hirose, Y.3    Aldape, K.D.4    McMahon, M.5    Berger, M.S.6
  • 33
    • 19944431335 scopus 로고    scopus 로고
    • Identification of a novel small-molecule inhibitor of the hypoxiainducible factor 1 pathway
    • Tan C, de Noronha RG, Roecker AJ, Pyrzynska B, Khwaja F, Zhang Z, et al. Identification of a novel small-molecule inhibitor of the hypoxiainducible factor 1 pathway. Cancer Res 2005;65:605-12.
    • (2005) Cancer Res , vol.65 , pp. 605-612
    • Tan, C.1    De Noronha, R.G.2    Roecker, A.J.3    Pyrzynska, B.4    Khwaja, F.5    Zhang, Z.6
  • 34
    • 0037470141 scopus 로고    scopus 로고
    • The erk/mapk pathway regulates the activity of the human tissue factor pathway inhibitor-2 promoter
    • Kast C, Wang M, Whiteway M. The ERK/MAPK pathway regulates the activity of the human tissue factor pathway inhibitor-2 promoter. J Biol Chem 2003;278:6787-94.
    • (2003) J Biol Chem , vol.278 , pp. 6787-6794
    • Kast, C.1    Wang, M.2    Whiteway, M.3
  • 35
    • 0032549711 scopus 로고    scopus 로고
    • Arf promotes mdm2 degradation and stabilizes p53: Arf-ink4a locus deletion impairs both the rb and p53 tumor suppression pathways
    • Zhang Y, Xiong Y, Yarbrough WG. ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways. Cell 1998;92:725-34.
    • (1998) Cell , vol.92 , pp. 725-734
    • Zhang, Y.1    Xiong, Y.2    Yarbrough, W.G.3
  • 36
    • 0038513758 scopus 로고    scopus 로고
    • Characterization and functional analysis of tfpi-2 gene promoter in a human choriocarcinoma cell line
    • Hube F, Reverdiau P, Iochmann S, Cherpi-Antar C, Gruel Y. Characterization and functional analysis of TFPI-2 gene promoter in a human choriocarcinoma cell line. Thromb Res 2003;109:207-15.
    • (2003) Thromb Res , vol.109 , pp. 207-215
    • Hube, F.1    Reverdiau, P.2    Iochmann, S.3    Cherpi-Antar, C.4    Gruel, Y.5
  • 37
    • 0035895809 scopus 로고    scopus 로고
    • Genomic structure and promoter activity of the human tissue factor pathway inhibitor-2 gene
    • Kamei S, Kazama Y, Kuijper JL, Foster DC, Kisiel W. Genomic structure and promoter activity of the human tissue factor pathway inhibitor-2 gene. Biochim Biophys Acta 2001;1517:430-5.
    • (2001) Biochim Biophys Acta , vol.1517 , pp. 430-435
    • Kamei, S.1    Kazama, Y.2    Kuijper, J.L.3    Foster, D.C.4    Kisiel, W.5
  • 38
    • 0027938445 scopus 로고
    • C-jun nterminal phosphorylation correlates with activation of the jnk subgroup but not the erk subgroup of mitogen-Activated protein kinases
    • Minden A, Lin A, Smeal T, Derijard B, Cobb M, Davis R, et al. c-Jun Nterminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-Activated protein kinases. Mol Cell Biol 1994;14:6683-8.
    • (1994) Mol Cell Biol , vol.14 , pp. 6683-6688
    • Minden, A.1    Lin, A.2    Smeal, T.3    Derijard, B.4    Cobb, M.5    Davis, R.6
  • 39
    • 0031882775 scopus 로고    scopus 로고
    • Activation of coagulation and angiogenesis in cancer: Immunohistochemical localization in situ of clotting proteins and vascular endothelial growth factor in human cancer
    • Shoji M, Hancock WW, Abe K, Micko C, Casper KA, Baine RM, et al. Activation of coagulation and angiogenesis in cancer: immunohistochemical localization in situ of clotting proteins and vascular endothelial growth factor in human cancer. Am J Pathol 1998;152:399-411.
    • (1998) Am J Pathol , vol.152 , pp. 399-411
    • Shoji, M.1    Hancock, W.W.2    Abe, K.3    Micko, C.4    Casper, K.A.5    Baine, R.M.6
  • 40
    • 33746696738 scopus 로고    scopus 로고
    • Pseudopalisading necrosis in glioblastoma: A familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis
    • Rong Y, Durden DL, Van Meir EG, Brat DJ. 'Pseudopalisading' necrosis in glioblastoma: a familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis. J Neuropathol Exp Neurol 2006;65:529-39.
    • (2006) J Neuropathol Exp Neurol , vol.65 , pp. 529-539
    • Rong, Y.1    Durden, D.L.2    Van Meir, E.G.3    Brat, D.J.4
  • 41
    • 0028343509 scopus 로고
    • Molecular cloning, expression, and partial characterization of a second human tissue-factor-pathway inhibitor
    • Sprecher CA, Kisiel W, Mathewes S, Foster DC. Molecular cloning, expression, and partial characterization of a second human tissue-factor-pathway inhibitor. Proc Natl Acad Sci U S A 1994; 91:3353-7.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 3353-3357
    • Sprecher, C.A.1    Kisiel, W.2    Mathewes, S.3    Foster, D.C.4
  • 42
    • 0034895082 scopus 로고    scopus 로고
    • Expression of tissue factor pathway inhibitor 2 inversely correlates during the progression of human gliomas
    • Rao CN, Lakka SS, Kin Y, Konduri SD, Fuller GN, Mohanam S, et al. Expression of tissue factor pathway inhibitor 2 inversely correlates during the progression of human gliomas. Clin Cancer Res 2001; 7:570-6.
    • (2001) Clin Cancer Res , vol.7 , pp. 570-576
    • Rao, C.N.1    Lakka, S.S.2    Kin, Y.3    Konduri, S.D.4    Fuller, G.N.5    Mohanam, S.6
  • 43
    • 84872567667 scopus 로고    scopus 로고
    • Associations between tfpi-2 methylation and poor prognosis in glioblastomas
    • Vaitkiene P, Skiriute D, Skauminas K, Tamasauskas A. Associations between TFPI-2 methylation and poor prognosis in glioblastomas. Medicina (Kaunas) 2012;48:345-9.
    • (2012) Medicina (Kaunas , vol.48 , pp. 345-349
    • Vaitkiene, P.1    Skiriute, D.2    Skauminas, K.3    Tamasauskas, A.4
  • 44
    • 13444291198 scopus 로고    scopus 로고
    • Epigenetic inactivation of tfpi-2 as a common mechanism associated with growth and invasion of pancreatic ductal adenocarcinoma
    • Sato N, Parker AR, Fukushima N, Miyagi Y, Iacobuzio-Donahue CA, Eshleman JR, et al. Epigenetic inactivation of TFPI-2 as a common mechanism associated with growth and invasion of pancreatic ductal adenocarcinoma. Oncogene 2005;24:850-8.
    • (2005) Oncogene , vol.24 , pp. 850-858
    • Sato, N.1    Parker, A.R.2    Fukushima, N.3    Miyagi, Y.4    Iacobuzio-Donahue, C.A.5    Eshleman, J.R.6
  • 45
    • 64049109677 scopus 로고    scopus 로고
    • Identification of genes epigenetically silenced by cpg methylation in human gastric carcinoma
    • Jee CD, Kim MA, Jung EJ, Kim J, Kim WH. Identification of genes epigenetically silenced by CpG methylation in human gastric carcinoma. Eur J Cancer 2009;45:1282-93.
    • (2009) Eur J Cancer , vol.45 , pp. 1282-1293
    • Jee, C.D.1    Kim, M.A.2    Jung, E.J.3    Kim, J.4    Kim, W.H.5
  • 46
    • 84859198864 scopus 로고    scopus 로고
    • Methylation of tfpi-2 is an early event of esophageal carcinogenesis
    • Jia Y, Yang Y, Brock MV, Cao B, Zhan Q, Li Y, et al. Methylation of TFPI-2 is an early event of esophageal carcinogenesis. Epigenomics 2012;4:135-46.
    • (2012) Epigenomics , vol.4 , pp. 135-146
    • Jia, Y.1    Yang, Y.2    Brock, M.V.3    Cao, B.4    Zhan, Q.5    Li, Y.6
  • 47
    • 85047696388 scopus 로고    scopus 로고
    • Minimal and inducible regulation of tissue factor pathway inhibitor-2 in human gliomas
    • Konduri SD, Osman FA, Rao CN, Srinivas H, Yanamandra N, Tasiou A, et al. Minimal and inducible regulation of tissue factor pathway inhibitor-2 in human gliomas. Oncogene 2002;21:921-8.
    • (2002) Oncogene , vol.21 , pp. 921-928
    • Konduri, S.D.1    Osman, F.A.2    Rao, C.N.3    Srinivas, H.4    Yanamandra, N.5    Tasiou, A.6
  • 48
    • 0030605403 scopus 로고    scopus 로고
    • The regulation of ap-1 activity by mitogen-Activated protein kinases
    • Karin M. The regulation of AP-1 activity by mitogen-Activated protein kinases. Philos Trans R Soc Lond B Biol Sci 1996;351:127-34.
    • (1996) Philos Trans R Soc Lond B Biol Sci , vol.351 , pp. 127-134
    • Karin, M.1
  • 49
    • 1842476109 scopus 로고    scopus 로고
    • Activation mechanism and physiological roles of stress-Activated protein kinase/c-jun nh2-Terminal kinase in mammalian cells
    • Nishina H, Nakagawa K, Azuma N, Katada T. Activation mechanism and physiological roles of stress-Activated protein kinase/c-Jun NH2-Terminal kinase in mammalian cells. J Biol Regul Homeost Agents 2003;17:295-302.
    • (2003) J Biol Regul Homeost Agents , vol.17 , pp. 295-302
    • Nishina, H.1    Nakagawa, K.2    Azuma, N.3    Katada, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.